Cancer metastasis database

Annotation category 5

Gene information

Gene ID 643
Symbol

CXCR5

Synonymous

BLR1|CD185|MDR15

Full name

chemokine (C-X-C motif) receptor 5

Gene description

Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)|Burkitt lymphoma receptor 1, GTP-binding protein|C-X-C chemokine receptor type 5|CXC-R5|CXCR-5|MDR-15|monocyte-derived receptor 15

Cytoband

11q23.3

Gene type

protein-coding

Synonymous

MIM:601613; HGNC:HGNC:1060; HPRD:03367

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.258G>A; p.T86T; 11:118893802-118893802

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1048C>T; p.Q350*; 11:118894592-118894592

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Nonsense

c.3G>T; p.M1I; 11:118883944-118883944

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1067G>A; p.R356H; 11:118894611-118894611

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.439C>T; p.R147C; 11:118893983-118893983

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.782C>T; p.A261V; 11:118894326-118894326

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.902C>T; p.P301L; 11:118894446-118894446

 skinmalignant_melanomaSubstitution - Missense

c.602G>A; p.R201H; 11:118894146-118894146

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.151G>A; p.A51T; 11:118893695-118893695

 skinmalignant_melanomaSubstitution - Missense

c.1089_1090delAG; p.N365fs*>8; 11:118894633-118894634

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.988C>T; p.R330C; 11:118894532-118894532

 pancreascarcinoma; acinar_carcinomaSubstitution - Missense

c.54C>T; p.F18F; 11:118893598-118893598

 breastcarcinomaSubstitution - coding silent

c.85G>A; p.D29N; 11:118893629-118893629

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.85G>A; p.D29N; 11:118893629-118893629

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.831C>T; p.I277I; 11:118894375-118894375

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.762G>A; p.R254R; 11:118894306-118894306

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.165C>T; p.P55P; 11:118893709-118893709

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.854C>T; p.A285V; 11:118894398-118894398

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.854C>T; p.A285V; 11:118894398-118894398

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.528_529GG>AA; p.G177S; 11:118894072-118894073

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1044G>A; p.L348L; 11:118894588-118894588

 pituitary; craniopharyngeal_ductcraniopharyngioma; adamantinomatousSubstitution - coding silent

c.1002G>A; p.S334S; 11:118894546-118894546

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.978C>T; p.G326G; 11:118894522-118894522

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.558C>A; p.L186L; 11:118894102-118894102

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.655C>T; p.R219*; 11:118894199-118894199

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.1119G>C; p.*373Y; 11:118894663-118894663

 kidneycarcinoma; clear_cell_renal_cell_carcinomaNonstop extension

c.117T>G; p.P39P; 11:118893661-118893661

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.562G>A; p.A188T; 11:118894106-118894106

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.578G>A; p.G193D; 11:118894122-118894122

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.126delG; p.L45fs*22; 11:118893670-118893670

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.635C>T; p.T212M; 11:118894179-118894179

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.747G>A; p.Q249Q; 11:118894291-118894291

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.885G>T; p.K295N; 11:118894429-118894429

 haematopoietic_and_lymphoid_tissue; lymph_nodelymphoid_neoplasm; diffuse_large_B_cell_lymphomaSubstitution - Missense

c.754C>T; p.P252S; 11:118894298-118894298

 skin; extremitymalignant_melanomaSubstitution - Missense

c.516C>T; p.T172T; 11:118894060-118894060

 skinmalignant_melanomaSubstitution - coding silent

c.665A>C; p.Y222S; 11:118894209-118894209

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; follicular_lymphomaSubstitution - Missense

c.609C>G; p.T203T; 11:118894153-118894153

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1014G>C; p.T338T; 11:118894558-118894558

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1014G>C; p.T338T; 11:118894558-118894558

 thyroidother; neoplasmSubstitution - coding silent

c.433G>A; p.V145M; 11:118893977-118893977

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.989G>A; p.R330H; 11:118894533-118894533

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.477C>T; p.R159R; 11:118894021-118894021

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.257C>T; p.T86M; 11:118893801-118893801

 prostatecarcinomaSubstitution - Missense

c.109C>T; p.L37F; 11:118893653-118893653

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.781G>T; p.A261S; 11:118894325-118894325

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.353G>A; p.G118E; 11:118893897-118893897

 skinmalignant_melanomaSubstitution - Missense

c.332G>A; p.G111D; 11:118893876-118893876

 skinmalignant_melanomaSubstitution - Missense

c.322G>A; p.V108M; 11:118893866-118893866

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1108A>T; p.T370S; 11:118894652-118894652

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.301G>A; p.V101I; 11:118893845-118893845

 skinmalignant_melanomaSubstitution - Missense

c.512G>A; p.G171E; 11:118894056-118894056

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.327C>T; p.A109A; 11:118893871-118893871

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.583C>T; p.H195Y; 11:118894127-118894127

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.127G>A; p.G43R; 11:118893671-118893671

 skinmalignant_melanomaSubstitution - Missense

c.297G>A; p.L99L; 11:118893841-118893841

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.282C>T; p.A94A; 11:118893826-118893826

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.587A>T; p.N196I; 11:118894131-118894131

 large_intestineNSSubstitution - Missense

c.751C>T; p.R251C; 11:118894295-118894295

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1119G>T; p.*373Y; 11:118894663-118894663

 lungcarcinoma; small_cell_carcinomaNonstop extension

c.100G>A; p.E34K; 11:118893644-118893644

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.976G>A; p.G326S; 11:118894520-118894520

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.387_388insA; p.V131fs*178; 11:118893931-118893932

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaInsertion - Frameshift

c.561C>T; p.F187F; 11:118894105-118894105

 pancreascarcinoma; ductal_carcinomaSubstitution - coding silent

c.475C>T; p.R159C; 11:118894019-118894019

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.36G>A; p.E12E; 11:118883977-118883977

 skinmalignant_melanomaSubstitution - coding silent

c.1108A>C; p.T370P; 11:118894652-118894652

 breastcarcinomaSubstitution - Missense