Cancer metastasis database

Annotation category 5

Gene information

Gene ID 6386
Symbol

SDCBP

Synonymous

MDA-9|MDA9|ST1|SYCL|TACIP18

Full name

syndecan binding protein (syntenin)

Gene description

melanoma differentiation associated protein-9|melanoma differentiation-associated protein 9|pro-TGF-alpha cytoplasmic domain-interacting protein 18|scaffold protein Pbp1|syndecan-binding protein 1|syntenin-1

Cytoband

8q12

Gene type

protein-coding

Synonymous

MIM:602217; HGNC:HGNC:10662; Ensembl:ENSG00000137575; HPRD:03741; Vega:OTTHUMG00000164303

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.115A>C; p.I39L; 8:58570950-58570950

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.199C>T; p.R67C; 8:58572273-58572273

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.750G>A; p.K250K; 8:58579794-58579794

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.750G>A; p.K250K; 8:58579794-58579794

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.221C>T; p.S74F; 8:58572295-58572295

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.559A>G; p.T187A; 8:58578189-58578189

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.764C>T; p.A255V; 8:58580530-58580530

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.426G>A; p.Q142Q; 8:58578056-58578056

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.609G>A; p.K203K; 8:58579653-58579653

 breastcarcinomaSubstitution - coding silent

c.305G>A; p.G102E; 8:58575964-58575964

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.531G>T; p.V177V; 8:58578161-58578161

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.531G>T; p.V177V; 8:58578161-58578161

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.787A>G; p.T263A; 8:58580553-58580553

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.787A>G; p.T263A; 8:58580553-58580553

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.839A>C; p.K280T; 8:58580605-58580605

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; acute_lymphoblastic_leukaemiaSubstitution - Missense

c.65T>G; p.F22C; 8:58570900-58570900

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.408A>G; p.I136M; 8:58578038-58578038

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.408A>G; p.I136M; 8:58578038-58578038

 large_intestine; coloncarcinomaSubstitution - Missense

c.528G>T; p.K176N; 8:58578158-58578158

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.527A>T; p.K176M; 8:58578157-58578157

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.677C>A; p.S226Y; 8:58579721-58579721

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.378A>T; p.G126G; 8:58576037-58576037

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.841C>T; p.R281W; 8:58580607-58580607

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.833T>C; p.I278T; 8:58580599-58580599

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.473T>C; p.V158A; 8:58578103-58578103

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.541G>A; p.A181T; 8:58578171-58578171

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.514G>C; p.D172H; 8:58578144-58578144

 cervixcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.478C>T; p.Q160*; 8:58578108-58578108

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.386T>C; p.L129P; 8:58576045-58576045

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.89C>A; p.A30E; 8:58570924-58570924

 livercarcinomaSubstitution - Missense

c.392C>G; p.S131*; 8:58576051-58576051

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.783T>A; p.S261S; 8:58580549-58580549

 bone; pelvisEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.564G>T; p.M188I; 8:58578194-58578194

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.579-6T>C; p.?; 8:58579617-58579617

 skin; head_neckmalignant_melanoma; superficial_spreadingUnknown

c.117C>T; p.I39I; 8:58570952-58570952

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - coding silent

c.843G>C; p.R281R; 8:58581686-58581686

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.26A>C; p.D9A; 8:58565059-58565059

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.311G>A; p.R104H; 8:58575970-58575970

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.654A>G; p.I218M; 8:58579698-58579698

 skinmalignant_melanomaSubstitution - Missense

c.133C>A; p.L45I; 8:58572207-58572207

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.560_561CC>TT; p.T187I; 8:58578190-58578191

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense