lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6288
Symbol	SAA1
Synonymous	PIG4\|SAA\|SAA2\|TP53I4
Full name	serum amyloid A1
Gene description	serum amyloid A protein\|serum amyloid A-1 protein\|tumor protein p53 inducible protein 4
Cytoband	11p15.1
Gene type	protein-coding
Synonymous	MIM:104750; HGNC:HGNC:10513; Ensembl:ENSG00000173432; HPRD:00097; Vega:OTTHUMG00000166147

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.162delC; p.H55fs*21; 11:18269265-18269265	liver	carcinoma; hepatocellular_carcinoma	Deletion - Frameshift
c.295G>A; p.A99T; 11:18269781-18269781	skin	malignant_melanoma	Substitution - Missense
c.121G>A; p.D41N; 11:18269224-18269224	skin	malignant_melanoma	Substitution - Missense
c.299C>T; p.A100V; 11:18269785-18269785	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.74T>A; p.L25H; 11:18266961-18266961	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.68C>T; p.S23L; 11:18266955-18266955	skin	malignant_melanoma	Substitution - Missense
c.68C>T; p.S23L; 11:18266955-18266955	skin	malignant_melanoma	Substitution - Missense
c.68C>T; p.S23L; 11:18266955-18266955	skin	malignant_melanoma	Substitution - Missense
c.282G>A; p.S94S; 11:18269768-18269768	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.308G>A; p.W103*; 11:18269794-18269794	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	thyroid	other; neoplasm	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.224T>C; p.V75A; 11:18269327-18269327	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.63C>A; p.F21L; 11:18266950-18266950	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.38T>C; p.V13A; 11:18266925-18266925	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.325G>C; p.D109H; 11:18269811-18269811	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.216T>C; p.A72A; 11:18269319-18269319	breast	carcinoma	Substitution - coding silent
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.216T>C; p.A72A; 11:18269319-18269319	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.216T>C; p.A72A; 11:18269319-18269319	thyroid	other; neoplasm	Substitution - coding silent
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.230C>G; p.T77S; 11:18269333-18269333	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.239G>A; p.R80K; 11:18269725-18269725	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.288T>C; p.A96A; 11:18269774-18269774	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	thyroid	other; neoplasm	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 11:18269312-18269312	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.249C>T; p.I83I; 11:18269735-18269735	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.273G>A; p.A91A; 11:18269759-18269759	bone; rib	chondrosarcoma	Substitution - coding silent
c.79G>A; p.E27K; 11:18266966-18266966	breast	carcinoma	Substitution - Missense
c.360G>T; p.E120D; 11:18269846-18269846	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.55C>T; p.R19*; 11:18266942-18266942	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.258C>A; p.F86L; 11:18269744-18269744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>A; p.D78N; 11:18269718-18269718	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.42G>A; p.L14L; 11:18266929-18266929	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.43G>A; p.G15S; 11:18266930-18266930	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.350G>A; p.G117D; 11:18269836-18269836	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation