lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	6146
Symbol	RPL22
Synonymous	EAP\|HBP15\|HBP15/L22\|L22
Full name	ribosomal protein L22
Gene description	60S ribosomal protein L22\|EBER-associated protein\|Epstein-Barr virus small RNA-associated protein\|Epstein-Barr-encoded RNA-associated protein\|heparin-binding protein 15\|heparin-binding protein HBp15
Cytoband	1p36.31
Gene type	protein-coding
Synonymous	MIM:180474; HGNC:HGNC:10315; Ensembl:ENSG00000116251; HPRD:01602; Vega:OTTHUMG00000000953

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.301C>T; p.R101C; 1:6186758-6186758	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.83C>A; p.P28H; 1:6197686-6197686	pancreas	carcinoma	Substitution - Missense
c.243-1G>T; p.?; 1:6186817-6186817	liver	carcinoma	Unknown
c.243-1G>T; p.?; 1:6186817-6186817	liver	carcinoma	Unknown
c.116T>A; p.F39Y; 1:6197653-6197653	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.166C>T; p.L56F; 1:6193006-6193006	skin	malignant_melanoma	Substitution - Missense
c.264A>C; p.K88N; 1:6186795-6186795	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.151G>A; p.G51R; 1:6193021-6193021	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.302G>A; p.R101H; 1:6186757-6186757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.13-10A>G; p.?; 1:6197766-6197766	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.1A>C; p.M1L; 1:6199573-6199573	skin; trunk	malignant_melanoma	Substitution - Missense
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.43_44delAA; p.K15fs*9; 1:6197725-6197726	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.43_44delAA; p.K15fs*9; 1:6197725-6197726	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	skin	malignant_melanoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.43_44delAA; p.K15fs*9; 1:6197725-6197726	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.44delA; p.K15fs*5; 1:6197725-6197725	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.254A>G; p.Y85C; 1:6186805-6186805	liver	carcinoma	Substitution - Missense
c.141C>G; p.I47M; 1:6193031-6193031	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1A>T; p.M1L; 1:6199573-6199573	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.45_46insA; p.Q17fs*8; 1:6197723-6197724	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Insertion - Frameshift
c.289C>T; p.R97C; 1:6186770-6186770	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.268T>C; p.Y90H; 1:6186791-6186791	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.44_45insA; p.K16fs*9; 1:6197724-6197725	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.44_45insA; p.K16fs*9; 1:6197724-6197725	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.266A>C; p.K89T; 1:6186793-6186793	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.12+1G>A; p.?; 1:6199561-6199561	liver	carcinoma	Unknown
c.101T>G; p.M34R; 1:6197668-6197668	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.246T>A; p.Y82*; 1:6186813-6186813	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.311C>A; p.A104D; 1:6186748-6186748	liver	carcinoma	Substitution - Missense
c.311C>A; p.A104D; 1:6186748-6186748	liver	carcinoma	Substitution - Missense
c.288A>C; p.L96L; 1:6186771-6186771	breast	carcinoma	Substitution - coding silent
c.257T>C; p.L86P; 1:6186802-6186802	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.125T>C; p.F42S; 1:6193047-6193047	skin	malignant_melanoma	Substitution - Missense
c.267delA; p.K89fs*3; 1:6186792-6186792	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.267delA; p.K89fs*3; 1:6186792-6186792	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.267delA; p.K89fs*3; 1:6186792-6186792	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.304G>A; p.V102I; 1:6186755-6186755	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.223G>T; p.E75*; 1:6192949-6192949	skin	malignant_melanoma	Substitution - Nonsense
c.103G>A; p.D35N; 1:6197666-6197666	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation