lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5920
Symbol	RARRES3
Synonymous	HRASLS4\|HRSL4\|PLA1/2-3\|RIG1\|TIG3
Full name	retinoic acid receptor responder (tazarotene induced) 3
Gene description	HRAS-like suppressor 4\|RAR-responsive protein TIG3\|retinoic acid receptor responder protein 3\|retinoic acid-inducible gene 1\|retinoid-inducible gene 1 protein\|tazarotene-induced gene 3 protein
Cytoband	11q23
Gene type	protein-coding
Synonymous	MIM:605092; HGNC:HGNC:9869; Ensembl:ENSG00000133321; HPRD:05479; Vega:OTTHUMG00000167850

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.264C>T; p.P88P; 11:63544766-63544766	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.396G>A; p.K132K; 11:63546157-63546157	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.191G>A; p.R64H; 11:63544693-63544693	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.191G>A; p.R64H; 11:63544693-63544693	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.413G>A; p.G138D; 11:63546174-63546174	skin	malignant_melanoma	Substitution - Missense
c.329G>T; p.S110I; 11:63544831-63544831	urinary_tract; bladder	carcinoma	Substitution - Missense
c.162G>A; p.L54L; 11:63544664-63544664	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.152T>A; p.F51Y; 11:63544654-63544654	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.109G>T; p.A37S; 11:63539615-63539615	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.21G>T; p.E7D; 11:63539527-63539527	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.21G>T; p.E7D; 11:63539527-63539527	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.476delA; p.A162fs*>3; 11:63546237-63546237	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.276C>T; p.I92I; 11:63544778-63544778	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.389T>G; p.V130G; 11:63546150-63546150	breast	carcinoma	Substitution - Missense
c.319A>G; p.S107G; 11:63544821-63544821	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.257C>T; p.P86L; 11:63544759-63544759	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.190C>T; p.R64C; 11:63544692-63544692	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.431G>A; p.G144E; 11:63546192-63546192	skin	malignant_melanoma	Substitution - Missense
c.34G>A; p.D12N; 11:63539540-63539540	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.236G>A; p.S79N; 11:63544738-63544738	skin	malignant_melanoma	Substitution - Missense
c.20A>G; p.E7G; 11:63539526-63539526	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.20A>G; p.E7G; 11:63539526-63539526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.20A>G; p.E7G; 11:63539526-63539526	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.45G>T; p.E15D; 11:63539551-63539551	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.86G>C; p.G29A; 11:63539592-63539592	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.462G>A; p.A154A; 11:63546223-63546223	skin	malignant_melanoma	Substitution - coding silent
c.96C>T; p.Y32Y; 11:63539602-63539602	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.223C>T; p.R75W; 11:63544725-63544725	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.52C>T; p.R18C; 11:63539558-63539558	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.327G>A; p.V109V; 11:63544829-63544829	breast	carcinoma	Substitution - coding silent
c.88G>T; p.D30Y; 11:63539594-63539594	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.475C>A; p.Q159K; 11:63546236-63546236	skin	malignant_melanoma	Substitution - Missense
c.397G>A; p.A133T; 11:63546158-63546158	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.292G>A; p.E98K; 11:63544794-63544794	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.120T>A; p.S40R; 11:63544622-63544622	thyroid	other; neoplasm	Substitution - Missense
c.129C>T; p.P43P; 11:63544631-63544631	skin	malignant_melanoma	Substitution - coding silent
c.122A>G; p.E41G; 11:63544624-63544624	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.122A>G; p.E41G; 11:63544624-63544624	liver	carcinoma	Substitution - Missense
c.122A>G; p.E41G; 11:63544624-63544624	liver	carcinoma	Substitution - Missense
c.422C>T; p.T141M; 11:63546183-63546183	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.470G>A; p.R157K; 11:63546231-63546231	skin	malignant_melanoma	Substitution - Missense
c.492C>T; p.A164A; 11:63546253-63546253	skin	malignant_melanoma	Substitution - coding silent
c.180G>A; p.V60V; 11:63544682-63544682	breast	carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation