Cancer metastasis database

Annotation category 5

Gene information

Gene ID 5898
Symbol

RALA

Synonymous

RAL

Full name

v-ral simian leukemia viral oncogene homolog A (ras related)

Gene description

RAS-like protein A|Ras family small GTP binding protein RALA|ras related GTP binding protein A|ras-related protein Ral-A

Cytoband

7p15-p13

Gene type

protein-coding

Synonymous

MIM:179550; HGNC:HGNC:9839; Ensembl:ENSG00000006451; HPRD:01549; Vega:OTTHUMG00000128775

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.334T>G; p.L112V; 7:39696695-39696695

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.245A>G; p.Y82C; 7:39690512-39690512

 skin; trunkmalignant_melanomaSubstitution - Missense

c.189G>T; p.Q63H; 7:39690456-39690456

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.439G>T; p.E147*; 7:39696800-39696800

 prostatecarcinoma; adenocarcinomaSubstitution - Nonsense

c.67G>A; p.G23S; 7:39686734-39686734

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.62G>C; p.G21A; 7:39686729-39686729

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.187C>T; p.Q63*; 7:39690454-39690454

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.503T>G; p.F168C; 7:39706127-39706127

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.526C>T; p.R176*; 7:39706150-39706150

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.526C>T; p.R176*; 7:39706150-39706150

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.526C>T; p.R176*; 7:39706150-39706150

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.526C>T; p.R176*; 7:39706150-39706150

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.526C>T; p.R176*; 7:39706150-39706150

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.526C>T; p.R176*; 7:39706150-39706150

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.188A>G; p.Q63R; 7:39690455-39690455

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.323G>T; p.R108M; 7:39690590-39690590

 large_intestineadenomaSubstitution - Missense

c.19A>G; p.K7E; 7:39686686-39686686

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.348A>T; p.E116D; 7:39696709-39696709

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.192C>T; p.I64I; 7:39690459-39690459

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.114+1G>T; p.?; 7:39686782-39686782

 central_nervous_system; braingliomaUnknown

c.593G>T; p.R198I; 7:39706217-39706217

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.115-2A>T; p.?; 7:39690380-39690380

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.115-2A>T; p.?; 7:39690380-39690380

 kidneycarcinoma; clear_cell_renal_cell_carcinomaUnknown

c.30T>G; p.N10K; 7:39686697-39686697

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.531G>T; p.A177A; 7:39706155-39706155

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.175G>T; p.G59W; 7:39690442-39690442

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.74T>A; p.V25E; 7:39686741-39686741

 salivary_glandcarcinoma; adenoid_cystic_carcinomaSubstitution - Missense

c.262G>T; p.G88W; 7:39690529-39690529

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.242A>G; p.N81S; 7:39690509-39690509

 breastcarcinomaSubstitution - Missense

c.115-5T>C; p.?; 7:39690377-39690377

 livercarcinomaUnknown

c.330G>C; p.Q110H; 7:39696691-39696691

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.54C>A; p.I18I; 7:39686721-39686721

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.146A>G; p.D49G; 7:39690413-39690413

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.115-1G>A; p.?; 7:39690381-39690381

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.189G>A; p.Q63Q; 7:39690456-39690456

 skinmalignant_melanomaSubstitution - coding silent

c.460G>A; p.V154M; 7:39696821-39696821

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.400A>G; p.K134E; 7:39696761-39696761

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.59T>C; p.V20A; 7:39686726-39686726

 livercarcinomaSubstitution - Missense

c.59T>C; p.V20A; 7:39686726-39686726

 livercarcinomaSubstitution - Missense

c.250C>T; p.R84*; 7:39690517-39690517

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.528A>T; p.R176R; 7:39706152-39706152

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.42A>C; p.L14F; 7:39686709-39686709

 NSNSSubstitution - Missense

c.577A>T; p.K193*; 7:39706201-39706201

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Nonsense

c.32C>A; p.S11Y; 7:39686699-39686699

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.68G>A; p.G23D; 7:39686735-39686735

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; Burkitt_lymphomaSubstitution - Missense

c.324-4_324-3CC>TT; p.?; 7:39696681-39696682

 skin; head_neckcarcinoma; squamous_cell_carcinomaUnknown

c.520G>T; p.E174*; 7:39706144-39706144

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.251G>A; p.R84Q; 7:39690518-39690518

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.95T>A; p.L32Q; 7:39686762-39686762

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.472G>T; p.A158S; 7:39696833-39696833

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.175G>A; p.G59R; 7:39690442-39690442

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense