Cancer metastasis database

Annotation category 5

Gene information

Gene ID 5893
Symbol

RAD52

Synonymous

-

Full name

RAD52 homolog (S. cerevisiae)

Gene description

DNA repair protein RAD52 homolog|recombination protein RAD52|rhabdomyosarcoma antigen MU-RMS-40.23

Cytoband

12p13-p12.2

Gene type

protein-coding

Synonymous

MIM:600392; HGNC:HGNC:9824; Ensembl:ENSG00000002016; HPRD:11855; Vega:OTTHUMG00000090361

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.387T>C; p.S129S; 12:927225-927225

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.702G>A; p.P234P; 12:916662-916662

 ovaryother; neoplasmSubstitution - coding silent

c.175G>A; p.G59R; 12:931231-931231

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.480T>C; p.N160N; 12:925513-925513

 bone; extraskeletalEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.846G>A; p.P282P; 12:916363-916363

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.846G>A; p.P282P; 12:916363-916363

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.971C>T; p.T324I; 12:914118-914118

 livercarcinomaSubstitution - Missense

c.971C>T; p.T324I; 12:914118-914118

 livercarcinomaSubstitution - Missense

c.933A>G; p.K311K; 12:914465-914465

 livercarcinomaSubstitution - coding silent

c.1208C>G; p.S403C; 12:913440-913440

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.475G>T; p.G159W; 12:925518-925518

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.1087C>A; p.Q363K; 12:914002-914002

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.1156T>C; p.W386R; 12:913933-913933

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.297C>G; p.N99K; 12:929870-929870

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1061C>T; p.T354I; 12:914028-914028

 ovaryother; neoplasmSubstitution - Missense

c.1019A>C; p.D340A; 12:914070-914070

 central_nervous_system; braingliomaSubstitution - Missense

c.1009G>A; p.D337N; 12:914080-914080

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.333G>T; p.V111V; 12:929834-929834

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.829G>A; p.V277I; 12:916380-916380

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.540C>T; p.R180R; 12:925453-925453

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.348+2T>G; p.?; 12:929817-929817

 breastcarcinomaUnknown

c.915A>T; p.S305S; 12:914483-914483

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.958G>T; p.E320*; 12:914440-914440

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.1170T>G; p.T390T; 12:913919-913919

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.33A>G; p.G11G; 12:933026-933026

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1073T>A; p.L358*; 12:914016-914016

 central_nervous_system; braingliomaSubstitution - Nonsense

c.617A>C; p.N206T; 12:916747-916747

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.354T>C; p.G118G; 12:927258-927258

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.43C>A; p.H15N; 12:933016-933016

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1037C>A; p.S346*; 12:914052-914052

 thyroidother; neoplasmSubstitution - Nonsense

c.593C>T; p.P198L; 12:916771-916771

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1130A>T; p.Q377L; 12:913959-913959

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.1048G>A; p.D350N; 12:914041-914041

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.853G>C; p.E285Q; 12:916356-916356

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.950T>C; p.V317A; 12:914448-914448

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1037C>T; p.S346L; 12:914052-914052

 large_intestine; colonNSSubstitution - Missense

c.164G>A; p.R55H; 12:931242-931242

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.925C>T; p.L309L; 12:914473-914473

 skinmalignant_melanomaSubstitution - coding silent

c.700C>A; p.P234T; 12:916664-916664

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.467+9G>A; p.?; 12:927136-927136

 pancreascarcinomaUnknown

c.1185A>G; p.Q395Q; 12:913904-913904

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.209G>T; p.R70L; 12:930122-930122

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.343C>T; p.L115L; 12:929824-929824

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.137G>A; p.R46K; 12:931269-931269

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.646C>T; p.H216Y; 12:916718-916718

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.146C>T; p.P49L; 12:931260-931260

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.805C>T; p.R269W; 12:916404-916404

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.242A>G; p.Y81C; 12:930089-930089

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.373G>T; p.G125C; 12:927239-927239

 skinmalignant_melanomaSubstitution - Missense

c.378T>C; p.Y126Y; 12:927234-927234

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.891G>A; p.T297T; 12:914507-914507

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.891G>A; p.T297T; 12:914507-914507

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1210C>G; p.H404D; 12:913438-913438

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.859A>G; p.S287G; 12:916350-916350

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.313delG; p.V105fs*7; 12:929854-929854

 endometriumcarcinoma; endometrioid_carcinomaDeletion - Frameshift

c.475G>A; p.G159R; 12:925518-925518

 skinmalignant_melanomaSubstitution - Missense