Cancer metastasis database

Annotation category 5

Gene information

Gene ID 5888
Symbol

RAD51

Synonymous

BRCC5|HRAD51|HsRad51|HsT16930|MRMV2|RAD51A|RECA

Full name

RAD51 recombinase

Gene description

BRCA1/BRCA2-containing complex, subunit 5|DNA repair protein RAD51 homolog 1|RAD51 homolog A|RecA, E. coli, homolog of|RecA-like protein|recombination protein A

Cytoband

15q15.1

Gene type

protein-coding

Synonymous

MIM:179617; HGNC:HGNC:9817; Ensembl:ENSG00000051180; HPRD:01557; Vega:OTTHUMG00000130067

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.832A>C; p.M278L; 15:40729910-40729910

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.663A>G; p.V221V; 15:40729523-40729523

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.815A>T; p.Q272L; 15:40729893-40729893

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.644G>A; p.R215K; 15:40728824-40728824

 skinmalignant_melanomaSubstitution - Missense

c.981C>T; p.F327F; 15:40731139-40731139

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.168A>T; p.P56P; 15:40701144-40701144

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.200G>T; p.S67I; 15:40701176-40701176

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.449G>A; p.R150Q; 15:40718818-40718818

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.159_160insG; p.Y54fs*11; 15:40701135-40701136

 livercarcinoma; hepatocellular_carcinomaInsertion - Frameshift

c.774G>T; p.E258D; 15:40729634-40729634

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.774G>T; p.E258D; 15:40729634-40729634

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.774G>T; p.E258D; 15:40729634-40729634

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.774G>T; p.E258D; 15:40729634-40729634

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.774G>T; p.E258D; 15:40729634-40729634

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.810A>G; p.V270V; 15:40729888-40729888

 breastcarcinomaSubstitution - coding silent

c.543T>C; p.S181S; 15:40728723-40728723

 skinmalignant_melanomaSubstitution - coding silent

c.171G>T; p.K57N; 15:40701147-40701147

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.258C>A; p.F86L; 15:40706209-40706209

 breastcarcinomaSubstitution - Missense

c.477C>T; p.Y159Y; 15:40718846-40718846

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.486T>A; p.T162T; 15:40718855-40718855

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.626C>T; p.A209V; 15:40728806-40728806

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.803A>C; p.Q268P; 15:40729881-40729881

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.581C>T; p.A194V; 15:40728761-40728761

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.849_850insA; p.P286fs*37; 15:40729927-40729928

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.582G>A; p.A194A; 15:40728762-40728762

 autonomic_ganglianeuroblastomaSubstitution - coding silent

c.328G>C; p.D110H; 15:40706279-40706279

 stomachcarcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiableSubstitution - Missense

c.945C>T; p.Y315Y; 15:40731103-40731103

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.945C>T; p.Y315Y; 15:40731103-40731103

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - coding silent

c.936C>T; p.C312C; 15:40731094-40731094

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.530+9C>A; p.?; 15:40718908-40718908

 lungcarcinoma; squamous_cell_carcinomaUnknown

c.476A>C; p.Y159S; 15:40718845-40718845

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; essential_thrombocythaemiaSubstitution - Missense

c.826G>A; p.A276T; 15:40729904-40729904

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.109G>A; p.D37N; 15:40701085-40701085

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.698C>T; p.S233L; 15:40729558-40729558

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.375G>A; p.M125I; 15:40709056-40709056

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.653T>G; p.L218R; 15:40729513-40729513

 breastcarcinomaSubstitution - Missense

c.935G>A; p.C312Y; 15:40731093-40731093

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.370G>T; p.E124*; 15:40709051-40709051

 urinary_tract; bladdercarcinomaSubstitution - Nonsense

c.433C>T; p.Q145*; 15:40709114-40709114

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.616C>G; p.Q206E; 15:40728796-40728796

 urinary_tract; bladdercarcinomaSubstitution - Missense