lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5883
Symbol	RAD9A
Synonymous	RAD9
Full name	RAD9 homolog A (S. pombe)
Gene description	DNA repair exonuclease rad9 homolog A\|cell cycle checkpoint control protein RAD9A\|hRAD9
Cytoband	11q13.1-q13.2
Gene type	protein-coding
Synonymous	MIM:603761; HGNC:HGNC:9827; Ensembl:ENSG00000172613; HPRD:04788; Vega:OTTHUMG00000167670

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1093T>C; p.F365L; 11:67397476-67397476	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1093T>C; p.F365L; 11:67397476-67397476	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.640G>A; p.A214T; 11:67395992-67395992	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1010C>T; p.P337L; 11:67397316-67397316	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.70G>T; p.G24W; 11:67392196-67392196	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.311G>A; p.R104Q; 11:67393572-67393572	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.437G>A; p.R146H; 11:67393778-67393778	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.56C>T; p.S19F; 11:67392182-67392182	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.56C>T; p.S19F; 11:67392182-67392182	skin	malignant_melanoma	Substitution - Missense
c.485C>G; p.A162G; 11:67395751-67395751	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.198T>G; p.P66P; 11:67392746-67392746	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.299C>T; p.S100F; 11:67393560-67393560	skin	malignant_melanoma	Substitution - Missense
c.677T>G; p.L226R; 11:67396118-67396118	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.546C>T; p.H182H; 11:67395812-67395812	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.546C>T; p.H182H; 11:67395812-67395812	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.993C>A; p.P331P; 11:67397299-67397299	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.931G>A; p.E311K; 11:67397237-67397237	skin	malignant_melanoma	Substitution - Missense
c.333G>T; p.Q111H; 11:67393594-67393594	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.264G>A; p.A88A; 11:67393525-67393525	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.456delG; p.E154fs*13; 11:67395722-67395722	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.547_549delGAG; p.E183delE; 11:67395813-67395815	breast	carcinoma	Deletion - In frame
c.491C>A; p.A164D; 11:67395757-67395757	pancreas	carcinoma	Substitution - Missense
c.1014T>C; p.G338G; 11:67397320-67397320	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.927C>A; p.A309A; 11:67397233-67397233	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1014T>C; p.G338G; 11:67397320-67397320	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.687A>G; p.A229A; 11:67396128-67396128	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.253C>T; p.R85C; 11:67393514-67393514	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.707_708delTT; p.L236fs*5; 11:67396148-67396149	endometrium	carcinoma; endometrioid_carcinoma	Deletion - Frameshift
c.419C>T; p.S140L; 11:67393760-67393760	skin	malignant_melanoma	Substitution - Missense
c.1089A>C; p.S363S; 11:67397472-67397472	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.872G>A; p.S291N; 11:67396400-67396400	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.448C>T; p.R150W; 11:67393789-67393789	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.392C>T; p.S131F; 11:67393733-67393733	skin	malignant_melanoma	Substitution - Missense
c.235-6A>G; p.?; 11:67393490-67393490	soft_tissue; striated_muscle	rhabdomyosarcoma; alveolar	Unknown
c.660G>A; p.K220K; 11:67396012-67396012	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.387T>A; p.C129*; 11:67393728-67393728	breast	carcinoma	Substitution - Nonsense
c.403G>A; p.V135I; 11:67393744-67393744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.112C>T; p.L38F; 11:67392660-67392660	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.930G>A; p.M310I; 11:67397236-67397236	skin	malignant_melanoma	Substitution - Missense
c.300C>T; p.S100S; 11:67393561-67393561	skin	malignant_melanoma	Substitution - coding silent
c.21C>T; p.G7G; 11:67392065-67392065	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.535C>T; p.R179C; 11:67395801-67395801	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.71G>T; p.G24V; 11:67392197-67392197	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.268C>T; p.L90L; 11:67393529-67393529	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.420G>A; p.S140S; 11:67393761-67393761	urinary_tract; bladder	carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation