lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5732
Symbol	PTGER2
Synonymous	EP2
Full name	prostaglandin E receptor 2 (subtype EP2), 53kDa
Gene description	PGE receptor EP2 subtype\|PGE2 receptor EP2 subtype\|prostaglandin E receptor 2 (subtype EP2), 53kD\|prostaglandin E2 receptor EP2 subtype\|prostanoid EP2 receptor
Cytoband	14q22
Gene type	protein-coding
Synonymous	MIM:176804; HGNC:HGNC:9594; Ensembl:ENSG00000125384; HPRD:08905; Vega:OTTHUMG00000140300

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.188C>T; p.S63F; 14:52314736-52314736	skin	malignant_melanoma	Substitution - Missense
c.108G>T; p.V36V; 14:52314656-52314656	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.939G>A; p.W313*; 14:52327316-52327316	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Nonsense
c.875G>A; p.R292Q; 14:52327252-52327252	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.939G>A; p.W313*; 14:52327316-52327316	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Nonsense
c.126A>G; p.A42A; 14:52314674-52314674	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.844-1G>A; p.?; 14:52327220-52327220	breast	carcinoma	Unknown
c.951C>T; p.I317I; 14:52327328-52327328	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.158A>G; p.D53G; 14:52314706-52314706	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.450C>T; p.R150R; 14:52314998-52314998	liver	carcinoma	Substitution - coding silent
c.895C>T; p.Q299*; 14:52327272-52327272	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.450C>T; p.R150R; 14:52314998-52314998	liver	carcinoma	Substitution - coding silent
c.42G>A; p.E14E; 14:52314590-52314590	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.47G>C; p.R16P; 14:52314595-52314595	skin	malignant_melanoma	Substitution - Missense
c.592C>G; p.Q198E; 14:52315140-52315140	urinary_tract; bladder	carcinoma	Substitution - Missense
c.980G>C; p.R327P; 14:52327357-52327357	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.854A>G; p.Y285C; 14:52327231-52327231	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.595C>A; p.L199M; 14:52315143-52315143	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.354C>A; p.F118L; 14:52314902-52314902	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.326G>A; p.C109Y; 14:52314874-52314874	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.216C>T; p.T72T; 14:52314764-52314764	skin	malignant_melanoma	Substitution - coding silent
c.33G>A; p.E11E; 14:52314581-52314581	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.16A>C; p.N6H; 14:52314564-52314564	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.507G>A; p.S169S; 14:52315055-52315055	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.703G>A; p.G235R; 14:52315251-52315251	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.507G>A; p.S169S; 14:52315055-52315055	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.880G>A; p.E294K; 14:52327257-52327257	skin	malignant_melanoma	Substitution - Missense
c.880G>A; p.E294K; 14:52327257-52327257	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.880G>A; p.E294K; 14:52327257-52327257	skin	malignant_melanoma	Substitution - Missense
c.402C>G; p.R134R; 14:52314950-52314950	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.225G>A; p.V75V; 14:52314773-52314773	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.165G>T; p.G55G; 14:52314713-52314713	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.485C>A; p.A162E; 14:52315033-52315033	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.485C>A; p.A162E; 14:52315033-52315033	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.246C>T; p.T82T; 14:52314794-52314794	skin	malignant_melanoma	Substitution - coding silent
c.463G>A; p.A155T; 14:52315011-52315011	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1072C>T; p.L358F; 14:52327449-52327449	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.283C>T; p.R95W; 14:52314831-52314831	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.847T>G; p.F283V; 14:52327224-52327224	breast	carcinoma	Substitution - Missense
c.102C>T; p.A34A; 14:52314650-52314650	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.496C>T; p.L166F; 14:52315044-52315044	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.729C>T; p.G243G; 14:52315277-52315277	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.304C>T; p.L102L; 14:52314852-52314852	breast	carcinoma; ER-PR-positive_carcinoma	Substitution - coding silent
c.31G>A; p.E11K; 14:52314579-52314579	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.369G>A; p.T123T; 14:52314917-52314917	skin	malignant_melanoma	Substitution - coding silent
c.858G>A; p.M286I; 14:52327235-52327235	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.876A>C; p.R292R; 14:52327253-52327253	breast	carcinoma	Substitution - coding silent
c.217G>A; p.E73K; 14:52314765-52314765	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.775G>A; p.E259K; 14:52315323-52315323	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.14C>G; p.S5C; 14:52314562-52314562	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1004C>T; p.S335L; 14:52327381-52327381	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.819C>T; p.F273F; 14:52315367-52315367	skin	malignant_melanoma	Substitution - coding silent
c.815C>T; p.T272I; 14:52315363-52315363	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.947C>T; p.A316V; 14:52327324-52327324	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.284G>T; p.R95L; 14:52314832-52314832	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.695G>A; p.S232N; 14:52315243-52315243	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.96C>A; p.F32L; 14:52314644-52314644	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.628T>A; p.S210T; 14:52315176-52315176	kidney	other; neoplasm	Substitution - Missense
c.753G>A; p.G251G; 14:52315301-52315301	skin	malignant_melanoma	Substitution - coding silent
c.704G>T; p.G235V; 14:52315252-52315252	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.995G>A; p.C332Y; 14:52327372-52327372	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1051G>A; p.D351N; 14:52327428-52327428	skin	malignant_melanoma	Substitution - Missense
c.411G>A; p.S137S; 14:52314959-52314959	skin	malignant_melanoma	Substitution - coding silent
c.631G>A; p.V211M; 14:52315179-52315179	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.67G>A; p.E23K; 14:52314615-52314615	skin	malignant_melanoma	Substitution - Missense
c.843G>A; p.T281T; 14:52315391-52315391	breast	carcinoma	Substitution - coding silent
c.404A>G; p.Y135C; 14:52314952-52314952	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.662A>G; p.N221S; 14:52315210-52315210	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation