Cancer metastasis database

Annotation category 5

Gene information

Gene ID 573
Symbol

BAG1

Synonymous

BAG-1|HAP|RAP46

Full name

BCL2-associated athanogene

Gene description

BAG family molecular chaperone regulator 1|Bcl-2 associating athanogene-1 protein|Bcl-2-binding protein|glucocortoid receptor-associated protein RAP46|receptor-associated protein, 46-KD

Cytoband

9p12

Gene type

protein-coding

Synonymous

MIM:601497; HGNC:HGNC:937; Ensembl:ENSG00000107262; HPRD:03292

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1031C>T; p.A344V; 9:33255226-33255226

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.823G>A; p.D275N; 9:33256863-33256863

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.374A>G; p.D125G; 9:33264301-33264301

 central_nervous_system; brainglioma; astrocytoma_Grade_IISubstitution - Missense

c.374A>G; p.D125G; 9:33264301-33264301

 central_nervous_system; brainglioma; astrocytoma_Grade_IISubstitution - Missense

c.643G>A; p.V215I; 9:33261107-33261107

 pancreascarcinomaSubstitution - Missense

c.263_280del18; p.R88_T93delRSEELT; 9:33264395-33264412

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaDeletion - In frame

c.220A>G; p.K74E; 9:33264455-33264455

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.675G>T; p.Q225H; 9:33259022-33259022

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.31_32insCC; p.R11fs*63; 9:33264643-33264644

 livercarcinomaInsertion - Frameshift

c.675G>T; p.Q225H; 9:33259022-33259022

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.133G>C; p.G45R; 9:33264542-33264542

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.133G>C; p.G45R; 9:33264542-33264542

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.789C>T; p.P263P; 9:33256897-33256897

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.703C>T; p.H235Y; 9:33258994-33258994

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.991C>T; p.Q331*; 9:33255266-33255266

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.32G>A; p.R11Q; 9:33264643-33264643

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.383C>T; p.S128L; 9:33264292-33264292

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.383C>T; p.S128L; 9:33264292-33264292

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.899A>T; p.N300I; 9:33255914-33255914

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.945T>C; p.V315V; 9:33255868-33255868

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.219G>A; p.K73K; 9:33264456-33264456

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.176C>T; p.P59L; 9:33264499-33264499

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.901T>G; p.F301V; 9:33255912-33255912

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.373G>A; p.D125N; 9:33264302-33264302

 central_nervous_system; brainglioma; astrocytoma_Grade_IISubstitution - Missense

c.373G>A; p.D125N; 9:33264302-33264302

 central_nervous_system; brainglioma; astrocytoma_Grade_IISubstitution - Missense

c.243C>T; p.T81T; 9:33264432-33264432

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.941_942insA; p.V315fs*9; 9:33255871-33255872

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.465C>T; p.H155H; 9:33262817-33262817

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.465C>T; p.H155H; 9:33262817-33262817

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.658A>G; p.K220E; 9:33261092-33261092

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.868G>A; p.E290K; 9:33256818-33256818

 pancreascarcinomaSubstitution - Missense

c.868G>A; p.E290K; 9:33256818-33256818

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.192C>T; p.A64A; 9:33264483-33264483

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.601G>A; p.E201K; 9:33261149-33261149

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.745G>C; p.E249Q; 9:33258952-33258952

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.745G>C; p.E249Q; 9:33258952-33258952

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.593_594AG>GA; p.K198R; 9:33261156-33261157

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.696G>T; p.K232N; 9:33259001-33259001

 ovaryother; neoplasmSubstitution - Missense

c.128C>T; p.P43L; 9:33264547-33264547

 skinmalignant_melanomaSubstitution - Missense

c.655G>A; p.G219R; 9:33261095-33261095

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.941delA; p.K314fs*6; 9:33255872-33255872

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.992A>G; p.Q331R; 9:33255265-33255265

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.280C>A; p.L94M; 9:33264395-33264395

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1003C>T; p.R335W; 9:33255254-33255254

 pancreascarcinomaSubstitution - Missense

c.1003C>T; p.R335W; 9:33255254-33255254

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.608C>T; p.P203L; 9:33261142-33261142

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.298T>G; p.W100G; 9:33264377-33264377

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.298T>G; p.W100G; 9:33264377-33264377

 upper_aerodigestive_tract; mouthcarcinomaSubstitution - Missense

c.1030G>A; p.A344T; 9:33255227-33255227

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1030G>A; p.A344T; 9:33255227-33255227

 large_intestine; coloncarcinomaSubstitution - Missense

c.1030G>A; p.A344T; 9:33255227-33255227

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.422C>T; p.A141V; 9:33264253-33264253

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.422C>T; p.A141V; 9:33264253-33264253

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.406A>T; p.R136W; 9:33264269-33264269

 thyroidother; neoplasmSubstitution - Missense

c.983A>G; p.N328S; 9:33255274-33255274

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.345G>A; p.E115E; 9:33264330-33264330

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.405C>A; p.T135T; 9:33264270-33264270

 thyroidother; neoplasmSubstitution - coding silent

c.711G>C; p.E237D; 9:33258986-33258986

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.711G>C; p.E237D; 9:33258986-33258986

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense