lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	57107
Symbol	PDSS2
Synonymous	C6orf210\|COQ10D3\|DLP1\|bA59I9.3\|hDLP1
Full name	prenyl (decaprenyl) diphosphate synthase, subunit 2
Gene description	all-trans-decaprenyl-diphosphate synthase subunit 2\|decaprenyl pyrophosphate synthase subunit 2\|decaprenyl pyrophosphate synthetase subunit 2\|decaprenyl-diphosphate synthase subunit 2\|subunit 2 of decaprenyl diphosphate synthase
Cytoband	6q21
Gene type	protein-coding
Synonymous	MIM:610564; HGNC:HGNC:23041; Ensembl:ENSG00000164494; HPRD:12879; Vega:OTTHUMG00000059359

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.7T>C; p.F3L; 6:107459279-107459279	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1002C>T; p.I334I; 6:107210445-107210445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.595G>A; p.A199T; 6:107274064-107274064	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.586C>T; p.L196L; 6:107274073-107274073	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.877A>G; p.I293V; 6:107210570-107210570	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.667G>C; p.V223L; 6:107245583-107245583	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.88G>T; p.D30Y; 6:107459198-107459198	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.474T>C; p.A158A; 6:107274185-107274185	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.474T>C; p.A158A; 6:107274185-107274185	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.247C>G; p.Q83E; 6:107459039-107459039	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1127T>C; p.L376P; 6:107154692-107154692	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.392C>T; p.S131L; 6:107334237-107334237	skin	malignant_melanoma	Substitution - Missense
c.735G>C; p.S245S; 6:107212250-107212250	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.193T>C; p.S65P; 6:107459093-107459093	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.887A>T; p.D296V; 6:107210560-107210560	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.381C>T; p.S127S; 6:107334248-107334248	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.552A>C; p.G184G; 6:107274107-107274107	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.105G>A; p.V35V; 6:107459181-107459181	skin	malignant_melanoma	Substitution - coding silent
c.40C>T; p.L14F; 6:107459246-107459246	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.927G>C; p.M309I; 6:107210520-107210520	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.939A>G; p.L313L; 6:107210508-107210508	breast	carcinoma	Substitution - coding silent
c.208C>A; p.R70S; 6:107459078-107459078	urinary_tract; bladder	carcinoma	Substitution - Missense
c.418G>C; p.G140R; 6:107334211-107334211	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.668T>C; p.V223A; 6:107245582-107245582	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.668T>C; p.V223A; 6:107245582-107245582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.364G>T; p.A122S; 6:107334265-107334265	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.217C>T; p.L73L; 6:107459069-107459069	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.96C>A; p.I32I; 6:107459190-107459190	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.847T>C; p.Y283H; 6:107212138-107212138	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.504A>G; p.L168L; 6:107274155-107274155	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.177C>T; p.I59I; 6:107459109-107459109	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.81G>A; p.P27P; 6:107459205-107459205	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.925A>G; p.M309V; 6:107210522-107210522	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.219G>A; p.L73L; 6:107459067-107459067	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.33A>C; p.P11P; 6:107459253-107459253	breast	carcinoma	Substitution - coding silent
c.1097G>A; p.R366H; 6:107154722-107154722	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.772T>G; p.L258V; 6:107212213-107212213	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.856C>T; p.H286Y; 6:107212129-107212129	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.575G>A; p.G192E; 6:107274084-107274084	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.474T>G; p.A158A; 6:107274185-107274185	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.104T>C; p.V35A; 6:107459182-107459182	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.472G>T; p.A158S; 6:107274187-107274187	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.669A>T; p.V223V; 6:107245581-107245581	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.349C>T; p.L117F; 6:107334280-107334280	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.973C>A; p.L325I; 6:107210474-107210474	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.863C>T; p.A288V; 6:107212122-107212122	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.482T>A; p.V161E; 6:107274177-107274177	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.484C>T; p.H162Y; 6:107274175-107274175	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.626C>G; p.T209S; 6:107274033-107274033	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.950C>T; p.P317L; 6:107210497-107210497	skin	malignant_melanoma	Substitution - Missense
c.692C>A; p.S231Y; 6:107245558-107245558	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.11G>C; p.R4P; 6:107459275-107459275	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.11G>C; p.R4P; 6:107459275-107459275	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1051A>T; p.R351*; 6:107154768-107154768	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1056C>A; p.I352I; 6:107154763-107154763	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.833A>G; p.N278S; 6:107212152-107212152	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.815A>C; p.H272P; 6:107212170-107212170	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1125C>T; p.A375A; 6:107154694-107154694	skin	malignant_melanoma	Substitution - coding silent
c.446C>T; p.A149V; 6:107274213-107274213	breast	carcinoma	Substitution - Missense
c.473C>T; p.A158V; 6:107274186-107274186	pancreas	carcinoma	Substitution - Missense
c.139G>A; p.A47T; 6:107459147-107459147	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.44G>T; p.G15V; 6:107459242-107459242	lung	carcinoma; large_cell_carcinoma	Substitution - Missense
c.56C>T; p.S19F; 6:107459230-107459230	urinary_tract; bladder	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation