lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	56937
Symbol	PMEPA1
Synonymous	STAG1\|TMEPAI
Full name	prostate transmembrane protein, androgen induced 1
Gene description	prostate transmembrane protein androgen induced 1\|protein TMEPAI\|solid tumor-associated 1 protein\|transmembrane, prostate androgen induced RNA
Cytoband	20q13.31-q13.33
Gene type	protein-coding
Synonymous	MIM:606564; HGNC:HGNC:14107; Ensembl:ENSG00000124225; HPRD:09415; Vega:OTTHUMG00000032831

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.680G>A; p.G227E; 20:57652237-57652237	skin	malignant_melanoma	Substitution - Missense
c.436C>T; p.L146L; 20:57652481-57652481	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.552C>T; p.R184R; 20:57652365-57652365	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.552C>T; p.R184R; 20:57652365-57652365	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.459A>G; p.S153S; 20:57652458-57652458	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - coding silent
c.459A>G; p.S153S; 20:57652458-57652458	thyroid	other; neoplasm	Substitution - coding silent
c.174C>T; p.I58I; 20:57659633-57659633	skin	malignant_melanoma	Substitution - coding silent
c.357G>A; p.L119L; 20:57652560-57652560	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.515C>T; p.P172L; 20:57652402-57652402	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.286G>C; p.E96Q; 20:57653065-57653065	breast	carcinoma	Substitution - Missense
c.413C>T; p.P138L; 20:57652504-57652504	skin	malignant_melanoma	Substitution - Missense
c.148G>A; p.V50M; 20:57659659-57659659	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.412C>T; p.P138S; 20:57652505-57652505	skin	malignant_melanoma	Substitution - Missense
c.336G>A; p.P112P; 20:57652581-57652581	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - coding silent
c.791C>G; p.T264R; 20:57652126-57652126	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.632A>C; p.N211T; 20:57652285-57652285	prostate	carcinoma	Substitution - Missense
c.593A>T; p.D198V; 20:57652324-57652324	breast	carcinoma	Substitution - Missense
c.655T>C; p.Y219H; 20:57652262-57652262	liver	carcinoma	Substitution - Missense
c.655T>C; p.Y219H; 20:57652262-57652262	liver	carcinoma	Substitution - Missense
c.553G>A; p.A185T; 20:57652364-57652364	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.177G>A; p.T59T; 20:57659630-57659630	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.801G>A; p.A267A; 20:57652116-57652116	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.801G>A; p.A267A; 20:57652116-57652116	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.801G>A; p.A267A; 20:57652116-57652116	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.484C>T; p.Q162*; 20:57652433-57652433	skin	malignant_melanoma	Substitution - Nonsense
c.59T>C; p.V20A; 20:57709524-57709524	central_nervous_system; brain	glioma	Substitution - Missense
c.837G>C; p.K279N; 20:57652080-57652080	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.671G>A; p.R224H; 20:57652246-57652246	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.492C>A; p.P164P; 20:57652425-57652425	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.850G>A; p.G284R; 20:57652067-57652067	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.479C>A; p.P160H; 20:57652438-57652438	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.384G>C; p.E128D; 20:57652533-57652533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.789_790insCCAC; p.T264fs*19; 20:57652127-57652128	peritoneum; appendix	other; pseudomyxoma_peritonei	Insertion - Frameshift
c.132C>T; p.I44I; 20:57659675-57659675	skin	malignant_melanoma	Substitution - coding silent
c.390C>T; p.F130F; 20:57652527-57652527	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.390C>T; p.F130F; 20:57652527-57652527	skin	malignant_melanoma	Substitution - coding silent
c.769G>T; p.E257*; 20:57652148-57652148	breast	carcinoma	Substitution - Nonsense
c.580_585delAGTGAC; p.S194_D195delSD; 20:57652332-57652337	breast	carcinoma	Deletion - In frame
c.650C>T; p.T217M; 20:57652267-57652267	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.501C>T; p.L167L; 20:57652416-57652416	skin	malignant_melanoma	Substitution - coding silent
c.488G>A; p.G163D; 20:57652429-57652429	skin	malignant_melanoma	Substitution - Missense
c.501C>T; p.L167L; 20:57652416-57652416	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.441A>G; p.P147P; 20:57652476-57652476	thyroid	other; neoplasm	Substitution - coding silent
c.441A>G; p.P147P; 20:57652476-57652476	thyroid	other; neoplasm	Substitution - coding silent
c.441A>G; p.P147P; 20:57652476-57652476	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.141C>T; p.I47I; 20:57659666-57659666	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.43G>A; p.A15T; 20:57709540-57709540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.349G>A; p.D117N; 20:57652568-57652568	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.367C>A; p.P123T; 20:57652550-57652550	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.795_796delCA; p.I266fs*15; 20:57652121-57652122	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.828C>T; p.S276S; 20:57652089-57652089	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.296T>C; p.V99A; 20:57653055-57653055	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.480C>T; p.P160P; 20:57652437-57652437	skin	malignant_melanoma	Substitution - coding silent
c.372C>T; p.F124F; 20:57652545-57652545	skin	malignant_melanoma	Substitution - coding silent
c.497C>T; p.T166I; 20:57652420-57652420	pancreas	NS	Substitution - Missense
c.464G>C; p.G155A; 20:57652453-57652453	skin	malignant_melanoma	Substitution - Missense
c.573C>G; p.I191M; 20:57652344-57652344	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.264A>G; p.S88S; 20:57659543-57659543	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.772G>A; p.G258R; 20:57652145-57652145	skin	malignant_melanoma	Substitution - Missense
c.605T>G; p.L202R; 20:57652312-57652312	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.508C>T; p.R170W; 20:57652409-57652409	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.670C>T; p.R224C; 20:57652247-57652247	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.852A>G; p.G284G; 20:57652065-57652065	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.624_625insC; p.S209fs*3; 20:57652292-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.624_625insC; p.S209fs*3; 20:57652292-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.624_625insC; p.S209fs*3; 20:57652292-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.624_625insC; p.S209fs*3; 20:57652292-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.522G>A; p.Q174Q; 20:57652395-57652395	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.814G>A; p.A272T; 20:57652103-57652103	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.624delC; p.S209fs*61; 20:57652293-57652293	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.624delC; p.S209fs*61; 20:57652293-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.624delC; p.S209fs*61; 20:57652293-57652293	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.624delC; p.S209fs*61; 20:57652293-57652293	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.636G>A; p.S212S; 20:57652281-57652281	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.624delC; p.S209fs*61; 20:57652293-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.624delC; p.S209fs*61; 20:57652293-57652293	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.624delC; p.S209fs*61; 20:57652293-57652293	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.386G>A; p.R129H; 20:57652531-57652531	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.698G>A; p.S233N; 20:57652219-57652219	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.433G>A; p.D145N; 20:57652484-57652484	skin	malignant_melanoma	Substitution - Missense
c.433G>A; p.D145N; 20:57652484-57652484	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation