lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	563
Symbol	AZGP1
Synonymous	ZA2G\|ZAG
Full name	alpha-2-glycoprotein 1, zinc-binding
Gene description	Alpha-2-glycoprotein, zinc\|Zn-alpha2-glycoprotein\|zinc-alpha-2-glycoprotein\|zn-alpha-2-GP\|zn-alpha-2-glycoprotein
Cytoband	7q22.1
Gene type	protein-coding
Synonymous	MIM:194460; HGNC:HGNC:910; Ensembl:ENSG00000160862; HPRD:01910; Vega:OTTHUMG00000023066

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.704T>G; p.I235S; 7:99967196-99967196	liver	carcinoma	Substitution - Missense
c.704T>G; p.I235S; 7:99967196-99967196	liver	carcinoma	Substitution - Missense
c.461G>C; p.W154S; 7:99968307-99968307	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.548A>G; p.E183G; 7:99968220-99968220	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.163G>T; p.D55Y; 7:99971920-99971920	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.338-10delG; p.?; 7:99968440-99968440	NS	malignant_melanoma	Unknown
c.12G>A; p.M4I; 7:99976009-99976009	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.386G>A; p.R129K; 7:99968382-99968382	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.703delA; p.I235fs*>64; 7:99967197-99967197	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.99C>A; p.I33I; 7:99971984-99971984	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.378G>T; p.E126D; 7:99968390-99968390	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.359G>A; p.R120K; 7:99968409-99968409	skin	malignant_melanoma	Substitution - Missense
c.337G>A; p.G113R; 7:99971746-99971746	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.337G>A; p.G113R; 7:99971746-99971746	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.820G>A; p.D274N; 7:99967080-99967080	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.18T>C; p.P6P; 7:99976003-99976003	breast	carcinoma	Substitution - coding silent
c.175T>G; p.F59V; 7:99971908-99971908	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.228G>T; p.Q76H; 7:99971855-99971855	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.76+10G>T; p.?; 7:99975935-99975935	ovary	other; neoplasm	Unknown
c.260G>A; p.S87N; 7:99971823-99971823	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.91A>T; p.T31S; 7:99971992-99971992	thyroid	other; neoplasm	Substitution - Missense
c.564G>A; p.A188A; 7:99968204-99968204	skin	malignant_melanoma	Substitution - coding silent
c.283G>A; p.D95N; 7:99971800-99971800	skin	malignant_melanoma	Substitution - Missense
c.80G>A; p.R27H; 7:99972003-99972003	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.755G>A; p.G252E; 7:99967145-99967145	skin	malignant_melanoma	Substitution - Missense
c.33G>A; p.L11L; 7:99975988-99975988	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.137C>T; p.A46V; 7:99971946-99971946	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.328G>A; p.D110N; 7:99971755-99971755	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.297G>T; p.E99D; 7:99971786-99971786	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.136G>A; p.A46T; 7:99971947-99971947	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.362T>G; p.F121C; 7:99968406-99968406	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.751C>T; p.R251W; 7:99967149-99967149	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.874G>C; p.V292L; 7:99967026-99967026	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.336C>T; p.N112N; 7:99971747-99971747	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.336C>T; p.N112N; 7:99971747-99971747	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.16C>T; p.P6S; 7:99976005-99976005	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.90G>C; p.L30L; 7:99971993-99971993	thyroid	other; neoplasm	Substitution - coding silent
c.81T>G; p.R27R; 7:99972002-99972002	oesophagus	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.613+1G>A; p.?; 7:99968154-99968154	stomach	carcinoma; adenocarcinoma	Unknown
c.613+1G>A; p.?; 7:99968154-99968154	stomach	carcinoma; adenocarcinoma	Unknown
c.288C>G; p.I96M; 7:99971795-99971795	thyroid	carcinoma	Substitution - Missense
c.725C>T; p.A242V; 7:99967175-99967175	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.790T>G; p.S264A; 7:99967110-99967110	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.533C>T; p.A178V; 7:99968235-99968235	breast	carcinoma	Substitution - Missense
c.772G>A; p.G258R; 7:99967128-99967128	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.161A>T; p.N54I; 7:99971922-99971922	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.397G>C; p.A133P; 7:99968371-99968371	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.327C>T; p.N109N; 7:99971756-99971756	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.327C>T; p.N109N; 7:99971756-99971756	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.621C>A; p.P207P; 7:99967279-99967279	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.582G>A; p.L194L; 7:99968186-99968186	skin	malignant_melanoma	Substitution - coding silent
c.397G>A; p.A133T; 7:99968371-99968371	prostate	carcinoma	Substitution - Missense
c.134C>T; p.P45L; 7:99971949-99971949	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.164A>G; p.D55G; 7:99971919-99971919	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.721C>T; p.R241W; 7:99967179-99967179	skin	malignant_melanoma	Substitution - Missense
c.418G>A; p.D140N; 7:99968350-99968350	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.418G>A; p.D140N; 7:99968350-99968350	skin	malignant_melanoma	Substitution - Missense
c.393C>T; p.S131S; 7:99968375-99968375	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.393C>T; p.S131S; 7:99968375-99968375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.837C>T; p.S279S; 7:99967063-99967063	skin	malignant_melanoma	Substitution - coding silent
c.832T>G; p.Y278D; 7:99967068-99967068	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.295G>A; p.E99K; 7:99971788-99971788	skin	malignant_melanoma	Substitution - Missense
c.761T>A; p.V254D; 7:99967139-99967139	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.375C>T; p.I125I; 7:99968393-99968393	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.21C>A; p.V7V; 7:99976000-99976000	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.462G>A; p.W154*; 7:99968306-99968306	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.462G>A; p.W154*; 7:99968306-99968306	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.341C>T; p.S114F; 7:99968427-99968427	skin	malignant_melanoma	Substitution - Missense
c.319T>C; p.Y107H; 7:99971764-99971764	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.292A>G; p.M98V; 7:99971791-99971791	central_nervous_system; temporoparietal	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.23T>A; p.L8Q; 7:99975998-99975998	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.563C>T; p.A188V; 7:99968205-99968205	oesophagus	carcinoma	Substitution - Missense
c.779G>A; p.G260D; 7:99967121-99967121	oesophagus	carcinoma	Substitution - Missense
c.294G>A; p.M98I; 7:99971789-99971789	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.61C>A; p.Q21K; 7:99975960-99975960	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.572G>A; p.R191Q; 7:99968196-99968196	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.467C>T; p.P156L; 7:99968301-99968301	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.394G>T; p.G132*; 7:99968374-99968374	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.757G>T; p.D253Y; 7:99967143-99967143	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.571C>T; p.R191W; 7:99968197-99968197	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.697G>A; p.G233R; 7:99967203-99967203	skin	malignant_melanoma	Substitution - Missense
c.465C>T; p.V155V; 7:99968303-99968303	skin	malignant_melanoma	Substitution - coding silent
c.131T>A; p.V44D; 7:99971952-99971952	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation