lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5579
Symbol	PRKCB
Synonymous	PKC-beta\|PKCB\|PRKCB1\|PRKCB2
Full name	protein kinase C, beta
Gene description	PKC-B\|protein kinase C beta type\|protein kinase C, beta 1 polypeptide
Cytoband	16p11.2
Gene type	protein-coding
Synonymous	MIM:176970; HGNC:HGNC:9395; Ensembl:ENSG00000166501; HPRD:01499; Vega:OTTHUMG00000131615

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1805A>T; p.Y602F; 16:24191172-24191172	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1536A>G; p.I512M; 16:24185113-24185113	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1149C>T; p.D383D; 16:24154767-24154767	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1149C>T; p.D383D; 16:24154767-24154767	lung	carcinoid-endocrine_tumour; typical	Substitution - coding silent
c.1116C>T; p.I372I; 16:24154734-24154734	skin	malignant_melanoma	Substitution - coding silent
c.1708G>A; p.A570T; 16:24185553-24185553	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1455T>C; p.F485F; 16:24180850-24180850	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.149G>C; p.C50S; 16:23836324-23836324	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.199T>A; p.C67S; 16:23837400-23837400	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.785G>T; p.G262V; 16:24094261-24094261	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1724T>C; p.L575P; 16:24191091-24191091	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1417_1418AT>TA; p.M473*; 16:24180812-24180813	skin	malignant_melanoma	Substitution - Nonsense
c.1682C>A; p.P561H; 16:24185527-24185527	skin	malignant_melanoma	Substitution - Missense
c.1803G>T; p.R601R; 16:24191170-24191170	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1448C>T; p.A483V; 16:24180843-24180843	skin	malignant_melanoma	Substitution - Missense
c.450G>T; p.L150L; 16:24035468-24035468	liver	carcinoma	Substitution - coding silent
c.1947G>A; p.R649R; 16:24214741-24214741	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1314C>T; p.F438F; 16:24172344-24172344	skin	malignant_melanoma	Substitution - coding silent
c.970A>G; p.T324A; 16:24123886-24123886	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1126G>A; p.D376N; 16:24154744-24154744	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1082G>A; p.R361Q; 16:24154700-24154700	skin	malignant_melanoma	Substitution - Missense
c.1082G>A; p.R361Q; 16:24154700-24154700	skin	malignant_melanoma	Substitution - Missense
c.1332A>T; p.V444V; 16:24174518-24174518	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1082G>A; p.R361Q; 16:24154700-24154700	skin	malignant_melanoma	Substitution - Missense
c.1191T>C; p.P397P; 16:24154809-24154809	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.260C>A; p.P87H; 16:23988562-23988562	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1043T>A; p.L348Q; 16:24123959-24123959	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1144G>A; p.D382N; 16:24154762-24154762	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1356C>G; p.I452M; 16:24174542-24174542	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.265G>T; p.A89S; 16:23988567-23988567	oesophagus	carcinoma	Substitution - Missense
c.1065G>T; p.K355N; 16:24123981-24123981	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1771G>A; p.E591K; 16:24191138-24191138	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1771G>A; p.E591K; 16:24191138-24191138	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1582G>C; p.G528R; 16:24185159-24185159	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.431T>C; p.V144A; 16:24035449-24035449	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.469G>A; p.E157K; 16:24035487-24035487	skin	malignant_melanoma	Substitution - Missense
c.1818G>A; p.E606E; 16:24191185-24191185	skin	malignant_melanoma	Substitution - coding silent
c.585C>T; p.Y195Y; 16:24092846-24092846	pancreas	carcinoma	Substitution - coding silent
c.603T>C; p.I201I; 16:24092864-24092864	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1443G>A; p.K481K; 16:24180838-24180838	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1218C>A; p.L406L; 16:24154836-24154836	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - coding silent
c.60C>T; p.F20F; 16:23836235-23836235	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1218C>A; p.L406L; 16:24154836-24154836	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - coding silent
c.1218C>A; p.L406L; 16:24154836-24154836	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - coding silent
c.1987A>C; p.N663H; 16:24214781-24214781	liver	carcinoma	Substitution - Missense
c.1987A>C; p.N663H; 16:24214781-24214781	liver	carcinoma	Substitution - Missense
c.786G>T; p.G262G; 16:24094262-24094262	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.18G>T; p.A6A; 16:23836193-23836193	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1211C>T; p.T404I; 16:24154829-24154829	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.450G>A; p.L150L; 16:24035468-24035468	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1860A>G; p.K620K; 16:24191227-24191227	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.962C>T; p.T321M; 16:24123878-24123878	skin	malignant_melanoma	Substitution - Missense
c.756G>A; p.R252R; 16:24094232-24094232	skin	malignant_melanoma	Substitution - coding silent
c.1856C>A; p.P619Q; 16:24191223-24191223	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.530T>C; p.V177A; 16:24092791-24092791	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.965C>T; p.T322I; 16:24123881-24123881	skin	malignant_melanoma	Substitution - Missense
c.1752G>T; p.L584L; 16:24191119-24191119	oesophagus	carcinoma	Substitution - coding silent
c.541delA; p.N182fs*15; 16:24092802-24092802	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1032C>T; p.F344F; 16:24123948-24123948	skin	malignant_melanoma	Substitution - coding silent
c.1382G>C; p.G461A; 16:24174568-24174568	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1422C>T; p.L474L; 16:24180817-24180817	skin	malignant_melanoma	Substitution - coding silent
c.1055G>A; p.S352N; 16:24123971-24123971	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1143T>C; p.D381D; 16:24154761-24154761	liver	carcinoma	Substitution - coding silent
c.1802G>A; p.R601Q; 16:24191169-24191169	skin	malignant_melanoma	Substitution - Missense
c.959A>G; p.K320R; 16:24123875-24123875	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1544A>T; p.Y515F; 16:24185121-24185121	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.545A>T; p.N182I; 16:24092806-24092806	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.765C>T; p.F255F; 16:24094241-24094241	skin	malignant_melanoma	Substitution - coding silent
c.1186C>T; p.L396L; 16:24154804-24154804	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1255G>T; p.V419L; 16:24172285-24172285	liver	carcinoma	Substitution - Missense
c.1255G>T; p.V419L; 16:24172285-24172285	breast	carcinoma	Substitution - Missense
c.1255G>T; p.V419L; 16:24172285-24172285	liver	carcinoma	Substitution - Missense
c.1904G>T; p.R635L; 16:24214698-24214698	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1892G>A; p.R631Q; 16:24214686-24214686	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1892G>A; p.R631Q; 16:24214686-24214686	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1892G>A; p.R631Q; 16:24214686-24214686	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.430G>A; p.V144M; 16:24035448-24035448	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.430G>A; p.V144M; 16:24035448-24035448	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.107A>C; p.N36T; 16:23836282-23836282	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.264C>T; p.G88G; 16:23988566-23988566	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1834G>C; p.E612Q; 16:24191201-24191201	breast	carcinoma	Substitution - Missense
c.79C>A; p.R27R; 16:23836254-23836254	thyroid	other; neoplasm	Substitution - coding silent
c.18G>A; p.A6A; 16:23836193-23836193	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1199C>T; p.P400L; 16:24154817-24154817	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1238_1239TG>AT; p.M413N; 16:24154856-24154857	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.785G>A; p.G262E; 16:24094261-24094261	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1554T>C; p.Y518Y; 16:24185131-24185131	breast	carcinoma	Substitution - coding silent
c.79C>A; p.R27R; 16:23836254-23836254	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.79C>A; p.R27R; 16:23836254-23836254	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.79C>A; p.R27R; 16:23836254-23836254	breast	carcinoma	Substitution - coding silent
c.649T>C; p.C217R; 16:24092910-24092910	skin	malignant_melanoma	Substitution - Missense
c.580C>T; p.P194S; 16:24092841-24092841	skin	malignant_melanoma	Substitution - Missense
c.1394G>A; p.R465H; 16:24174580-24174580	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.78C>T; p.L26L; 16:23836253-23836253	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.78C>T; p.L26L; 16:23836253-23836253	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.586G>A; p.V196I; 16:24092847-24092847	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1741G>T; p.G581C; 16:24191108-24191108	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1671C>T; p.N557N; 16:24185516-24185516	liver	carcinoma	Substitution - coding silent
c.1671C>T; p.N557N; 16:24185516-24185516	liver	carcinoma	Substitution - coding silent
c.1119G>A; p.L373L; 16:24154737-24154737	skin	malignant_melanoma	Substitution - coding silent
c.290_291insC; p.R99fs*7; 16:24032137-24032138	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.606C>T; p.P202P; 16:24092867-24092867	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.528C>A; p.L176L; 16:24035546-24035546	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1690A>G; p.M564V; 16:24185535-24185535	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1295T>C; p.I432T; 16:24172325-24172325	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.408G>A; p.M136I; 16:24035426-24035426	skin	malignant_melanoma	Substitution - Missense
c.296G>A; p.R99H; 16:24032143-24032143	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.61G>A; p.A21T; 16:23836236-23836236	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1871G>A; p.R624Q; 16:24214665-24214665	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1021G>A; p.D341N; 16:24123937-24123937	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.189G>T; p.Q63H; 16:23837390-23837390	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1913C>T; p.P638L; 16:24214707-24214707	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.532A>C; p.R178R; 16:24092793-24092793	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1450G>A; p.D484N; 16:24180845-24180845	skin	malignant_melanoma	Substitution - Missense
c.163G>A; p.D55N; 16:23836338-23836338	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.336C>T; p.P112P; 16:24032183-24032183	skin	malignant_melanoma	Substitution - coding silent
c.1339G>A; p.A447T; 16:24174525-24174525	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1846C>A; p.P616T; 16:24191213-24191213	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1885T>A; p.F629I; 16:24214679-24214679	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1395-4A>T; p.?; 16:24180786-24180786	kidney	other; neoplasm	Unknown
c.544A>T; p.N182Y; 16:24092805-24092805	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.544A>T; p.N182Y; 16:24092805-24092805	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.623G>A; p.S208N; 16:24092884-24092884	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1200G>A; p.P400P; 16:24154818-24154818	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1200G>A; p.P400P; 16:24154818-24154818	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1789C>G; p.H597D; 16:24191156-24191156	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1200G>A; p.P400P; 16:24154818-24154818	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1200G>A; p.P400P; 16:24154818-24154818	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.725T>C; p.V242A; 16:24094201-24094201	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1200G>A; p.P400P; 16:24154818-24154818	central_nervous_system; brain	glioma	Substitution - coding silent
c.1200G>A; p.P400P; 16:24154818-24154818	central_nervous_system; brain	glioma	Substitution - coding silent
c.1485G>A; p.G495G; 16:24180880-24180880	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1188G>T; p.L396L; 16:24154806-24154806	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1188G>T; p.L396L; 16:24154806-24154806	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1480G>A; p.D494N; 16:24180875-24180875	skin	malignant_melanoma	Substitution - Missense
c.1480G>A; p.D494N; 16:24180875-24180875	skin	malignant_melanoma	Substitution - Missense
c.1362G>C; p.L454L; 16:24174548-24174548	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1406T>C; p.L469P; 16:24180801-24180801	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1406T>C; p.L469P; 16:24180801-24180801	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1279G>A; p.D427N; 16:24172309-24172309	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.938G>T; p.G313V; 16:24123854-24123854	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1870C>T; p.R624*; 16:24214664-24214664	pancreas	carcinoma	Substitution - Nonsense
c.653C>T; p.S218F; 16:24092914-24092914	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1493C>T; p.T498I; 16:24180888-24180888	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.920G>T; p.R307M; 16:24123836-24123836	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.232T>C; p.C78R; 16:23988534-23988534	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1557G>A; p.G519G; 16:24185134-24185134	skin	malignant_melanoma	Substitution - coding silent
c.1486G>A; p.V496M; 16:24180881-24180881	central_nervous_system; brain	glioma	Substitution - Missense
c.1486G>A; p.V496M; 16:24180881-24180881	central_nervous_system; brain	glioma	Substitution - Missense
c.745T>A; p.L249M; 16:24094221-24094221	kidney	other; neoplasm	Substitution - Missense
c.1428T>C; p.S476S; 16:24180823-24180823	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.922G>A; p.A308T; 16:24123838-24123838	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1636G>T; p.E546*; 16:24185481-24185481	liver	carcinoma	Substitution - Nonsense
c.834G>A; p.L278L; 16:24112985-24112985	skin	malignant_melanoma	Substitution - coding silent
c.1093G>A; p.D365N; 16:24154711-24154711	breast	carcinoma	Substitution - Missense
c.177C>T; p.G59G; 16:23837378-23837378	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1698G>A; p.K566K; 16:24185543-24185543	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1904G>A; p.R635H; 16:24214698-24214698	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.285C>T; p.S95S; 16:23988587-23988587	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.285C>T; p.S95S; 16:23988587-23988587	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.309G>T; p.K103N; 16:24032156-24032156	thyroid	other; neoplasm	Substitution - Missense
c.607G>A; p.D203N; 16:24092868-24092868	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1068C>T; p.V356V; 16:24154686-24154686	skin	malignant_melanoma	Substitution - coding silent
c.607G>A; p.D203N; 16:24092868-24092868	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.668G>A; p.W223*; 16:24092929-24092929	skin	malignant_melanoma	Substitution - Nonsense
c.1768G>T; p.G590C; 16:24191135-24191135	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.731T>C; p.I244T; 16:24094207-24094207	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1567G>A; p.D523N; 16:24185144-24185144	skin	malignant_melanoma	Substitution - Missense
c.545delA; p.N182fs*15; 16:24092806-24092806	large_intestine; colon	carcinoma	Deletion - Frameshift
c.960G>A; p.K320K; 16:24123876-24123876	skin	malignant_melanoma	Substitution - coding silent
c.1357G>A; p.G453S; 16:24174543-24174543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.533G>A; p.R178K; 16:24092794-24092794	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1206C>T; p.F402F; 16:24154824-24154824	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.157T>G; p.C53G; 16:23836332-23836332	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.475C>T; p.R159C; 16:24035493-24035493	peritoneum; appendix	other; pseudomyxoma_peritonei	Substitution - Missense
c.657C>G; p.L219L; 16:24092918-24092918	breast	carcinoma	Substitution - coding silent
c.1525G>A; p.A509T; 16:24180920-24180920	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1525G>A; p.A509T; 16:24180920-24180920	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1525G>A; p.A509T; 16:24180920-24180920	large_intestine; colon	carcinoma	Substitution - Missense
c.56G>T; p.R19L; 16:23836231-23836231	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1525G>A; p.A509T; 16:24180920-24180920	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1525G>A; p.A509T; 16:24180920-24180920	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.55C>T; p.R19C; 16:23836230-23836230	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.52G>A; p.V18M; 16:23836227-23836227	skin	malignant_melanoma	Substitution - Missense
c.1968C>T; p.F656F; 16:24214762-24214762	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.756G>T; p.R252S; 16:24094232-24094232	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.477C>T; p.R159R; 16:24035495-24035495	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.263G>A; p.G88D; 16:23988565-23988565	pancreas	carcinoma	Substitution - Missense
c.1224C>G; p.S408S; 16:24154842-24154842	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1304T>C; p.V435A; 16:24172334-24172334	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1753G>A; p.G585S; 16:24191120-24191120	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1224C>G; p.S408S; 16:24154842-24154842	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1618C>T; p.P540S; 16:24185463-24185463	skin	malignant_melanoma	Substitution - Missense
c.1615G>A; p.A539T; 16:24185460-24185460	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1156T>C; p.C386R; 16:24154774-24154774	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1156T>A; p.C386S; 16:24154774-24154774	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1526C>T; p.A509V; 16:24180921-24180921	breast	carcinoma	Substitution - Missense
c.403T>G; p.C135G; 16:24035421-24035421	liver	carcinoma	Substitution - Missense
c.173+8C>T; p.?; 16:23836356-23836356	pancreas	carcinoma	Unknown
c.318C>T; p.I106I; 16:24032165-24032165	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.403T>G; p.C135G; 16:24035421-24035421	liver	carcinoma	Substitution - Missense
c.403T>G; p.C135G; 16:24035421-24035421	liver	carcinoma	Substitution - Missense
c.533G>T; p.R178I; 16:24092794-24092794	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.895G>A; p.E299K; 16:24113046-24113046	skin	malignant_melanoma	Substitution - Missense
c.1433G>A; p.G478E; 16:24180828-24180828	skin	malignant_melanoma	Substitution - Missense
c.2018G>A; p.S673N; 16:24214812-24214812	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1663G>A; p.E555K; 16:24185508-24185508	skin	malignant_melanoma	Substitution - Missense
c.560A>G; p.D187G; 16:24092821-24092821	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1550C>A; p.P517H; 16:24185127-24185127	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.716G>T; p.R239I; 16:24094192-24094192	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1893_1894insT; p.T634fs*19; 16:24214687-24214688	large_intestine; caecum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1774C>T; p.R592C; 16:24191141-24191141	breast	carcinoma	Substitution - Missense
c.1656C>T; p.S552S; 16:24185501-24185501	skin	malignant_melanoma	Substitution - coding silent
c.1636G>A; p.E546K; 16:24185481-24185481	skin	malignant_melanoma	Substitution - Missense
c.610C>T; p.P204S; 16:24092871-24092871	skin	malignant_melanoma	Substitution - Missense
c.1318G>A; p.E440K; 16:24172348-24172348	skin	malignant_melanoma	Substitution - Missense
c.1723C>T; p.L575L; 16:24191090-24191090	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1155G>T; p.E385D; 16:24154773-24154773	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1168G>A; p.E390K; 16:24154786-24154786	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.827A>T; p.K276M; 16:24112978-24112978	breast	carcinoma	Substitution - Missense
c.238G>A; p.E80K; 16:23988540-23988540	skin	malignant_melanoma	Substitution - Missense
c.1503C>A; p.F501L; 16:24180898-24180898	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1202C>A; p.P401H; 16:24154820-24154820	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1887C>T; p.F629F; 16:24214681-24214681	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1336T>C; p.Y446H; 16:24174522-24174522	skin	malignant_melanoma	Substitution - Missense
c.423G>A; p.K141K; 16:24035441-24035441	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.482G>A; p.R161H; 16:24035500-24035500	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.884G>T; p.S295I; 16:24113035-24113035	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1334T>C; p.F445S; 16:24174520-24174520	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1563C>T; p.S521S; 16:24185140-24185140	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.1039G>A; p.V347M; 16:24123955-24123955	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.286G>A; p.D96N; 16:23988588-23988588	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1044G>A; p.L348L; 16:24123960-24123960	breast	carcinoma	Substitution - coding silent
c.1854G>T; p.K618N; 16:24191221-24191221	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1332-9T>A; p.?; 16:24174509-24174509	liver	carcinoma	Unknown
c.229C>T; p.R77W; 16:23988531-23988531	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1546C>T; p.Q516*; 16:24185123-24185123	skin	malignant_melanoma	Substitution - Nonsense
c.1007G>A; p.R336Q; 16:24123923-24123923	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1007G>A; p.R336Q; 16:24123923-24123923	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1132G>A; p.V378M; 16:24154750-24154750	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.784G>T; p.G262W; 16:24094260-24094260	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1829G>A; p.R610H; 16:24191196-24191196	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation