lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	55750
Symbol	AGK
Synonymous	CATC5\|CTRCT38\|MTDPS10\|MULK
Full name	acylglycerol kinase
Gene description	acylglycerol kinase, mitochondrial\|hAGK\|hsMuLK\|multi-substrate lipid kinase\|multiple substrate lipid kinase
Cytoband	7q34
Gene type	protein-coding
Synonymous	MIM:610345; HGNC:HGNC:21869; HPRD:08554

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.556G>C; p.E186Q; 7:141621769-141621769	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1088C>T; p.T363M; 7:141651566-141651566	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1088C>T; p.T363M; 7:141651566-141651566	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.154C>G; p.Q52E; 7:141596574-141596574	breast	carcinoma	Substitution - Missense
c.469A>G; p.T157A; 7:141615516-141615516	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1055A>C; p.K352T; 7:141651533-141651533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.598G>C; p.E200Q; 7:141633910-141633910	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.352G>A; p.V118M; 7:141611249-141611249	breast	carcinoma	Substitution - Missense
c.1253C>G; p.T418R; 7:141652908-141652908	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.853T>C; p.S285P; 7:141641374-141641374	prostate	carcinoma	Substitution - Missense
c.775G>T; p.E259*; 7:141641296-141641296	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.499_500GA>TT; p.E167L; 7:141615546-141615547	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.851C>T; p.A284V; 7:141641372-141641372	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.851C>T; p.A284V; 7:141641372-141641372	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.821_840del20; p.L275fs*31; 7:141641342-141641361	breast	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.724A>T; p.K242*; 7:141637015-141637015	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.911A>G; p.K304R; 7:141641844-141641844	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.841C>T; p.R281*; 7:141641362-141641362	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.588+7C>G; p.?; 7:141621808-141621808	liver	carcinoma	Unknown
c.588+7C>G; p.?; 7:141621808-141621808	liver	carcinoma	Unknown
c.463G>A; p.G155R; 7:141615510-141615510	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.706C>T; p.H236Y; 7:141636997-141636997	skin	malignant_melanoma	Substitution - Missense
c.499G>A; p.E167K; 7:141615546-141615546	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.616A>G; p.M206V; 7:141633928-141633928	ovary	other; neoplasm	Substitution - Missense
c.616A>G; p.M206V; 7:141633928-141633928	ovary	other; neoplasm	Substitution - Missense
c.481A>C; p.S161R; 7:141615528-141615528	skin	malignant_melanoma	Substitution - Missense
c.975+1G>A; p.?; 7:141641909-141641909	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.732G>A; p.W244*; 7:141641253-141641253	skin	malignant_melanoma	Substitution - Nonsense
c.1094G>A; p.C365Y; 7:141651572-141651572	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.242_243insA; p.N83fs*17; 7:141601225-141601226	stomach	adenocarcinoma	Insertion - Frameshift
c.1110G>A; p.Q370Q; 7:141651588-141651588	thyroid	other; neoplasm	Substitution - coding silent
c.1138G>T; p.G380W; 7:141652793-141652793	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1171G>A; p.E391K; 7:141652826-141652826	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1180C>T; p.P394S; 7:141652835-141652835	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.637T>C; p.S213P; 7:141633949-141633949	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.500A>T; p.E167V; 7:141615547-141615547	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.716G>A; p.S239N; 7:141637007-141637007	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.488C>T; p.T163I; 7:141615535-141615535	skin	malignant_melanoma	Substitution - Missense
c.848T>C; p.L283P; 7:141641369-141641369	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.348G>A; p.T116T; 7:141611245-141611245	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.209C>T; p.A70V; 7:141596629-141596629	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.982G>A; p.E328K; 7:141649269-141649269	skin	malignant_melanoma	Substitution - Missense
c.242A>C; p.E81A; 7:141601225-141601225	central_nervous_system; brain	glioma	Substitution - Missense
c.17A>T; p.K6I; 7:141555483-141555483	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.19A>C; p.T7P; 7:141555485-141555485	skin	malignant_melanoma	Substitution - Missense
c.446T>A; p.I149N; 7:141615493-141615493	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1142G>C; p.G381A; 7:141652797-141652797	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.478T>G; p.L160V; 7:141615525-141615525	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.456C>T; p.I152I; 7:141615503-141615503	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.21G>A; p.T7T; 7:141555487-141555487	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.64C>T; p.L22L; 7:141555530-141555530	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.589G>T; p.G197C; 7:141633901-141633901	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.585C>A; p.I195I; 7:141621798-141621798	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.185A>T; p.K62M; 7:141596605-141596605	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.976-3T>C; p.?; 7:141649260-141649260	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Unknown
c.297+1G>A; p.?; 7:141601281-141601281	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.5C>T; p.T2M; 7:141555471-141555471	skin	malignant_melanoma	Substitution - Missense
c.26G>A; p.R9Q; 7:141555492-141555492	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.26G>A; p.R9Q; 7:141555492-141555492	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.26G>A; p.R9Q; 7:141555492-141555492	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.26G>A; p.R9Q; 7:141555492-141555492	breast	carcinoma	Substitution - Missense
c.751T>C; p.S251P; 7:141641272-141641272	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.26G>A; p.R9Q; 7:141555492-141555492	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.26G>A; p.R9Q; 7:141555492-141555492	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1051C>T; p.R351*; 7:141651529-141651529	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.655G>A; p.V219I; 7:141633967-141633967	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1089G>A; p.T363T; 7:141651567-141651567	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.630A>G; p.R210R; 7:141633942-141633942	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.152A>G; p.N51S; 7:141596572-141596572	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1058T>C; p.V353A; 7:141651536-141651536	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.368G>A; p.G123E; 7:141611265-141611265	pancreas	other; adenoma	Substitution - Missense
c.465A>G; p.G155G; 7:141615512-141615512	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.465A>G; p.G155G; 7:141615512-141615512	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.370G>A; p.G124R; 7:141611267-141611267	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.464G>T; p.G155V; 7:141615511-141615511	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.711T>G; p.F237L; 7:141637002-141637002	breast	carcinoma	Substitution - Missense
c.803C>A; p.T268N; 7:141641324-141641324	skin	malignant_melanoma	Substitution - Missense
c.96A>C; p.K32N; 7:141555562-141555562	thyroid	other; neoplasm	Substitution - Missense
c.1226A>G; p.D409G; 7:141652881-141652881	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.499G>T; p.E167*; 7:141615546-141615546	prostate	carcinoma; adenocarcinoma	Substitution - Nonsense
c.255C>A; p.A85A; 7:141601238-141601238	skin	malignant_melanoma	Substitution - coding silent
c.13T>C; p.F5L; 7:141555479-141555479	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.413G>A; p.R138Q; 7:141614168-141614168	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.784C>A; p.P262T; 7:141641305-141641305	skin	malignant_melanoma	Substitution - Missense
c.163C>T; p.P55S; 7:141596583-141596583	skin	malignant_melanoma	Substitution - Missense
c.686C>G; p.P229R; 7:141636977-141636977	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; mantle_cell_lymphoma	Substitution - Missense
c.347C>T; p.T116M; 7:141611244-141611244	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation