lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5529
Symbol	PPP2R5E
Synonymous	-
Full name	protein phosphatase 2, regulatory subunit B', epsilon isoform
Gene description	PP2A B subunit isoform B'-epsilon\|PP2A B subunit isoform B56-epsilon\|PP2A B subunit isoform PR61-epsilon\|PP2A B subunit isoform R5-epsilon\|PP2A, B subunit, B' epsilon\|PP2A, B subunit, B56 epsilon\|PP2A, B subunit, PR61 epsilon\|PP2A, B subunit, R5 epsilon\|e
Cytoband	14q23.1
Gene type	protein-coding
Synonymous	MIM:601647; HGNC:HGNC:9313; Ensembl:ENSG00000154001; HPRD:09040

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1215G>A; p.A405A; 14:63382145-63382145	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.160G>A; p.V54I; 14:63453883-63453883	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.440C>T; p.S147L; 14:63422009-63422009	skin	malignant_melanoma	Substitution - Missense
c.1155C>T; p.P385P; 14:63384491-63384491	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.237G>A; p.T79T; 14:63453806-63453806	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1008A>G; p.Q336Q; 14:63389678-63389678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.574G>T; p.D192Y; 14:63396692-63396692	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.862A>G; p.I288V; 14:63392013-63392013	pancreas	carcinoma	Substitution - Missense
c.158A>G; p.D53G; 14:63453885-63453885	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1169G>T; p.S390I; 14:63384477-63384477	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.986T>C; p.L329S; 14:63389700-63389700	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1362G>A; p.E454E; 14:63376051-63376051	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1201C>T; p.P401S; 14:63384445-63384445	skin	malignant_melanoma	Substitution - Missense
c.631C>T; p.L211F; 14:63396635-63396635	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.614G>T; p.R205I; 14:63396652-63396652	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.740+8C>T; p.?; 14:63395218-63395218	prostate	carcinoma	Unknown
c.934A>G; p.K312E; 14:63391837-63391837	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.8C>G; p.S3*; 14:63539678-63539678	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1377T>C; p.L459L; 14:63376036-63376036	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.89C>T; p.S30L; 14:63539597-63539597	skin	malignant_melanoma	Substitution - Missense
c.1139C>T; p.S380F; 14:63384507-63384507	skin	malignant_melanoma	Substitution - Missense
c.601delA; p.T201fs*26; 14:63396665-63396665	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1310A>T; p.K437I; 14:63376103-63376103	skin; arm	malignant_melanoma	Substitution - Missense
c.90G>A; p.S30S; 14:63539596-63539596	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1318G>C; p.E440Q; 14:63376095-63376095	skin	malignant_melanoma	Substitution - Missense
c.1139C>G; p.S380C; 14:63384507-63384507	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1220T>C; p.V407A; 14:63382140-63382140	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.24_26delTCC; p.P9delP; 14:63539660-63539662	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.28T>C; p.S10P; 14:63539658-63539658	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.28T>C; p.S10P; 14:63539658-63539658	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.215T>C; p.V72A; 14:63453828-63453828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1077G>T; p.V359V; 14:63384569-63384569	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.726G>T; p.L242L; 14:63395240-63395240	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.238C>G; p.L80V; 14:63453805-63453805	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.467A>C; p.E156A; 14:63415222-63415222	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.379C>T; p.L127F; 14:63422070-63422070	urinary_tract; bladder	carcinoma	Substitution - Missense
c.465T>C; p.Y155Y; 14:63415224-63415224	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1189G>T; p.E397*; 14:63384457-63384457	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1024G>T; p.E342*; 14:63389662-63389662	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.808C>A; p.P270T; 14:63393861-63393861	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1330G>A; p.E444K; 14:63376083-63376083	breast	carcinoma	Substitution - Missense
c.887C>T; p.P296L; 14:63391988-63391988	skin	malignant_melanoma	Substitution - Missense
c.681-6T>C; p.?; 14:63395291-63395291	pancreas	carcinoma; adenocarcinoma	Unknown
c.46G>A; p.G16R; 14:63539640-63539640	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1202+1G>A; p.?; 14:63384443-63384443	soft_tissue; striated_muscle	rhabdoid_tumour	Unknown
c.1202+1G>A; p.?; 14:63384443-63384443	stomach	carcinoma; adenocarcinoma	Unknown
c.402A>C; p.E134D; 14:63422047-63422047	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.973C>T; p.L325L; 14:63389713-63389713	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.355G>C; p.V119L; 14:63422094-63422094	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.379C>G; p.L127V; 14:63422070-63422070	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.479G>A; p.R160Q; 14:63415210-63415210	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.641G>T; p.R214I; 14:63396625-63396625	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.571G>A; p.E191K; 14:63396695-63396695	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.53C>G; p.S18C; 14:63539633-63539633	ovary	other; neoplasm	Substitution - Missense
c.269G>A; p.R90H; 14:63453774-63453774	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1314G>T; p.K438N; 14:63376099-63376099	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1045G>A; p.A349T; 14:63389641-63389641	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.545T>C; p.L182S; 14:63415144-63415144	pancreas	carcinoma	Substitution - Missense
c.270C>T; p.R90R; 14:63453773-63453773	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.729A>C; p.E243D; 14:63395237-63395237	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.234C>A; p.D78E; 14:63453809-63453809	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.823A>T; p.R275W; 14:63393846-63393846	prostate	carcinoma	Substitution - Missense
c.7T>C; p.S3P; 14:63539679-63539679	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.228C>G; p.F76L; 14:63453815-63453815	breast	carcinoma	Substitution - Missense
c.444G>A; p.W148*; 14:63422005-63422005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.98C>T; p.S33F; 14:63539588-63539588	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.580C>G; p.R194G; 14:63396686-63396686	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.66C>T; p.V22V; 14:63539620-63539620	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1214C>T; p.A405V; 14:63382146-63382146	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.10G>A; p.A4T; 14:63539676-63539676	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation