lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5469
Symbol	MED1
Synonymous	CRSP1\|CRSP200\|DRIP205\|DRIP230\|PBP\|PPARBP\|PPARGBP\|RB18A\|TRAP220\|TRIP2
Full name	mediator complex subunit 1
Gene description	ARC205\|PPAR binding protein\|PPAR-binding protein\|PPARG binding protein\|TR-interacting protein 2\|TRIP-2\|activator-recruited cofactor 205 kDa component\|mediator of RNA polymerase II transcription subunit 1\|p53 regulatory protein RB18A\|peroxisome proliferato
Cytoband	17q12
Gene type	protein-coding
Synonymous	MIM:604311; HGNC:HGNC:9234; Ensembl:ENSG00000125686; HPRD:05055; Vega:OTTHUMG00000133216

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.942T>A; p.S314S; 17:39423731-39423731	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.65G>A; p.R22Q; 17:39447865-39447865	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.805C>T; p.P269S; 17:39424673-39424673	skin	malignant_melanoma	Substitution - Missense
c.4157G>C; p.S1386T; 17:39408064-39408064	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2939A>G; p.N980S; 17:39409282-39409282	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2595C>T; p.F865F; 17:39409626-39409626	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.48G>A; p.M16I; 17:39447882-39447882	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2595C>T; p.F865F; 17:39409626-39409626	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3910A>G; p.T1304A; 17:39408311-39408311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3918C>T; p.V1306V; 17:39408303-39408303	breast	carcinoma	Substitution - coding silent
c.4004C>G; p.S1335C; 17:39408217-39408217	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.205C>A; p.L69I; 17:39443556-39443556	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1118G>A; p.C373Y; 17:39419896-39419896	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2141C>T; p.S714L; 17:39410080-39410080	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.632T>G; p.L211R; 17:39431132-39431132	prostate	adenoma	Substitution - Missense
c.4683C>A; p.S1561R; 17:39407538-39407538	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.2447C>A; p.S816Y; 17:39409774-39409774	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.4683C>A; p.S1561R; 17:39407538-39407538	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3653C>G; p.S1218C; 17:39408568-39408568	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4342C>G; p.P1448A; 17:39407879-39407879	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3203C>T; p.P1068L; 17:39409018-39409018	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1354G>A; p.V452I; 17:39415283-39415283	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3019G>C; p.D1007H; 17:39409202-39409202	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1077C>T; p.H359H; 17:39423345-39423345	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1233C>T; p.I411I; 17:39419781-39419781	skin	malignant_melanoma	Substitution - coding silent
c.3019G>C; p.D1007H; 17:39409202-39409202	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2612A>G; p.N871S; 17:39409609-39409609	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1355T>C; p.V452A; 17:39415282-39415282	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2164C>A; p.P722T; 17:39410057-39410057	skin	malignant_melanoma	Substitution - Missense
c.2613C>T; p.N871N; 17:39409608-39409608	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3806C>T; p.S1269F; 17:39408415-39408415	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2057A>C; p.K686T; 17:39410164-39410164	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1160G>C; p.S387T; 17:39419854-39419854	urinary_tract; bladder	carcinoma	Substitution - Missense
c.435A>C; p.K145N; 17:39434314-39434314	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.730G>A; p.E244K; 17:39427710-39427710	skin	malignant_melanoma	Substitution - Missense
c.3962delG; p.G1321fs*11; 17:39408259-39408259	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.4579A>G; p.S1527G; 17:39407642-39407642	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2429C>A; p.S810Y; 17:39409792-39409792	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2374A>C; p.K792Q; 17:39409847-39409847	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4224G>T; p.V1408V; 17:39407997-39407997	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.440T>C; p.F147S; 17:39434309-39434309	breast	carcinoma	Substitution - Missense
c.2012C>A; p.S671Y; 17:39410209-39410209	breast	carcinoma	Substitution - Missense
c.3800C>T; p.T1267M; 17:39408421-39408421	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2964A>C; p.L988F; 17:39409257-39409257	skin	malignant_melanoma	Substitution - Missense
c.4503A>C; p.K1501N; 17:39407718-39407718	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.861_864delCTTC; p.F288fs*17; 17:39423809-39423812	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1827A>G; p.Q609Q; 17:39410394-39410394	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2813G>A; p.G938D; 17:39409408-39409408	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.965A>G; p.Q322R; 17:39423708-39423708	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2937T>G; p.S979R; 17:39409284-39409284	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2246C>T; p.P749L; 17:39409975-39409975	liver	carcinoma	Substitution - Missense
c.2246C>T; p.P749L; 17:39409975-39409975	liver	carcinoma	Substitution - Missense
c.2508T>C; p.T836T; 17:39409713-39409713	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1841G>A; p.G614E; 17:39410380-39410380	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1704G>A; p.P568P; 17:39410517-39410517	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.4419G>C; p.E1473D; 17:39407802-39407802	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.4148A>T; p.N1383I; 17:39408073-39408073	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1687C>T; p.P563S; 17:39410534-39410534	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4120T>C; p.S1374P; 17:39408101-39408101	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.2098C>A; p.P700T; 17:39410123-39410123	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3283A>G; p.K1095E; 17:39408938-39408938	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1687C>A; p.P563T; 17:39410534-39410534	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.4574C>T; p.S1525F; 17:39407647-39407647	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1377T>C; p.N459N; 17:39415260-39415260	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1625C>A; p.P542Q; 17:39410596-39410596	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3641G>A; p.G1214E; 17:39408580-39408580	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4136C>T; p.S1379L; 17:39408085-39408085	urinary_tract; bladder	carcinoma	Substitution - Missense
c.4473A>G; p.E1491E; 17:39407748-39407748	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2123T>G; p.F708C; 17:39410098-39410098	skin	malignant_melanoma	Substitution - Missense
c.2521C>G; p.L841V; 17:39409700-39409700	ovary	other; neoplasm	Substitution - Missense
c.2230delC; p.Q744fs*36; 17:39409991-39409991	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.572A>G; p.Y191C; 17:39431945-39431945	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1437C>A; p.L479L; 17:39415088-39415088	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.856C>T; p.P286S; 17:39423817-39423817	skin	malignant_melanoma	Substitution - Missense
c.3680C>T; p.S1227L; 17:39408541-39408541	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2061C>A; p.T687T; 17:39410160-39410160	thyroid	other; neoplasm	Substitution - coding silent
c.4728G>T; p.V1576V; 17:39407493-39407493	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.16delG; p.E6fs*8; 17:39451047-39451047	skin; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.4148delA; p.N1383fs*26; 17:39408073-39408073	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2486A>G; p.N829S; 17:39409735-39409735	skin	malignant_melanoma	Substitution - Missense
c.2375A>G; p.K792R; 17:39409846-39409846	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4148delA; p.N1383fs*26; 17:39408073-39408073	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1304C>T; p.P435L; 17:39415333-39415333	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.4205C>G; p.P1402R; 17:39408016-39408016	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4222G>A; p.V1408M; 17:39407999-39407999	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3034C>T; p.R1012W; 17:39409187-39409187	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4493A>C; p.K1498T; 17:39407728-39407728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.606G>T; p.K202N; 17:39431158-39431158	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2376A>G; p.K792K; 17:39409845-39409845	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1423G>A; p.V475M; 17:39415102-39415102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3154C>T; p.P1052S; 17:39409067-39409067	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.388G>T; p.E130*; 17:39440397-39440397	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3148C>T; p.Q1050*; 17:39409073-39409073	oesophagus	carcinoma	Substitution - Nonsense
c.740-3C>T; p.?; 17:39424741-39424741	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.606G>C; p.K202N; 17:39431158-39431158	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3671C>T; p.P1224L; 17:39408550-39408550	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3881C>G; p.S1294C; 17:39408340-39408340	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.4533T>C; p.D1511D; 17:39407688-39407688	skin	malignant_melanoma	Substitution - coding silent
c.4536G>T; p.R1512S; 17:39407685-39407685	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2978G>A; p.G993E; 17:39409243-39409243	skin; upper_back	malignant_melanoma	Substitution - Missense
c.3977A>G; p.D1326G; 17:39408244-39408244	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.4546C>T; p.R1516W; 17:39407675-39407675	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4576C>G; p.H1526D; 17:39407645-39407645	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3384T>C; p.S1128S; 17:39408837-39408837	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2728A>T; p.M910L; 17:39409493-39409493	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3177C>G; p.P1059P; 17:39409044-39409044	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1568C>A; p.P523Q; 17:39410653-39410653	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2214C>T; p.I738I; 17:39410007-39410007	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3930G>A; p.L1310L; 17:39408291-39408291	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.3154_3155CC>TT; p.P1052F; 17:39409066-39409067	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3683G>A; p.G1228D; 17:39408538-39408538	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3342G>A; p.M1114I; 17:39408879-39408879	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4495A>T; p.K1499*; 17:39407726-39407726	thyroid	carcinoma	Substitution - Nonsense
c.362G>A; p.C121Y; 17:39440423-39440423	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3795C>A; p.S1265S; 17:39408426-39408426	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2863G>A; p.G955S; 17:39409358-39409358	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1754G>A; p.R585Q; 17:39410467-39410467	pancreas	carcinoma	Substitution - Missense
c.3065C>A; p.P1022Q; 17:39409156-39409156	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2863G>A; p.G955S; 17:39409358-39409358	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.626G>T; p.G209V; 17:39431138-39431138	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2429C>G; p.S810C; 17:39409792-39409792	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3536C>A; p.S1179*; 17:39408685-39408685	breast	carcinoma; ductal_carcinoma	Substitution - Nonsense
c.1763C>T; p.S588L; 17:39410458-39410458	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.4341T>C; p.S1447S; 17:39407880-39407880	liver	carcinoma	Substitution - coding silent
c.745C>T; p.R249*; 17:39424733-39424733	skin	malignant_melanoma	Substitution - Nonsense
c.1057G>C; p.D353H; 17:39423365-39423365	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.881C>T; p.A294V; 17:39423792-39423792	skin	malignant_melanoma	Substitution - Missense
c.3070C>T; p.H1024Y; 17:39409151-39409151	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.955C>T; p.Q319*; 17:39423718-39423718	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.30A>T; p.S10S; 17:39447900-39447900	thyroid	other; neoplasm	Substitution - coding silent
c.3146C>G; p.S1049C; 17:39409075-39409075	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2920G>T; p.E974*; 17:39409301-39409301	NS	NS	Substitution - Nonsense
c.1321G>A; p.E441K; 17:39415316-39415316	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4629C>T; p.S1543S; 17:39407592-39407592	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1963C>G; p.Q655E; 17:39410258-39410258	liver	carcinoma	Substitution - Missense
c.2290C>A; p.Q764K; 17:39409931-39409931	liver	carcinoma	Substitution - Missense
c.1592C>T; p.T531I; 17:39410629-39410629	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2290C>A; p.Q764K; 17:39409931-39409931	liver	carcinoma	Substitution - Missense
c.3991G>T; p.V1331L; 17:39408230-39408230	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1592C>T; p.T531I; 17:39410629-39410629	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1963C>G; p.Q655E; 17:39410258-39410258	liver	carcinoma	Substitution - Missense
c.1721_1722CC>TT; p.T574I; 17:39410499-39410500	skin	malignant_melanoma	Substitution - Missense
c.487C>A; p.L163I; 17:39434262-39434262	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.4576C>T; p.H1526Y; 17:39407645-39407645	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4738G>T; p.G1580W; 17:39407483-39407483	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1561G>A; p.D521N; 17:39410660-39410660	breast	carcinoma; ER-PR-positive_carcinoma	Substitution - Missense
c.1782C>T; p.D594D; 17:39410439-39410439	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3968A>G; p.D1323G; 17:39408253-39408253	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.4235A>G; p.K1412R; 17:39407986-39407986	liver	carcinoma	Substitution - Missense
c.4235A>G; p.K1412R; 17:39407986-39407986	liver	carcinoma	Substitution - Missense
c.3583C>T; p.H1195Y; 17:39408638-39408638	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2539G>A; p.G847R; 17:39409682-39409682	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3716C>T; p.S1239L; 17:39408505-39408505	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1839C>T; p.N613N; 17:39410382-39410382	ovary	other; neoplasm	Substitution - coding silent
c.685T>G; p.S229A; 17:39427755-39427755	liver	carcinoma	Substitution - Missense
c.688G>A; p.D230N; 17:39427752-39427752	breast	carcinoma	Substitution - Missense
c.3061_3064delTCTC; p.S1021fs*51; 17:39409157-39409160	large_intestine; colon	carcinoma	Deletion - Frameshift
c.2030G>A; p.R677H; 17:39410191-39410191	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3061_3064delTCTC; p.S1021fs*51; 17:39409157-39409160	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2030G>A; p.R677H; 17:39410191-39410191	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.407C>T; p.P136L; 17:39439186-39439186	skin; extremity	malignant_melanoma	Substitution - Missense
c.1709_1710insG; p.P571fs*7; 17:39410511-39410512	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.407C>T; p.P136L; 17:39439186-39439186	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1625delC; p.P542fs*9; 17:39410596-39410596	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3370A>C; p.S1124R; 17:39408851-39408851	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2018C>T; p.S673F; 17:39410203-39410203	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1575G>A; p.L525L; 17:39410646-39410646	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2018C>T; p.S673F; 17:39410203-39410203	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.828G>T; p.G276G; 17:39424650-39424650	liver	carcinoma	Substitution - coding silent
c.2018C>T; p.S673F; 17:39410203-39410203	urinary_tract; bladder	carcinoma	Substitution - Missense
c.413T>C; p.L138P; 17:39439180-39439180	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.3461G>A; p.G1154D; 17:39408760-39408760	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1384C>A; p.L462M; 17:39415253-39415253	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2365G>T; p.E789*; 17:39409856-39409856	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2799T>G; p.I933M; 17:39409422-39409422	stomach	adenocarcinoma	Substitution - Missense
c.3229C>T; p.P1077S; 17:39408992-39408992	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1019A>G; p.Y340C; 17:39423403-39423403	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.909C>T; p.F303F; 17:39423764-39423764	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.437delA; p.N146fs*24; 17:39434312-39434312	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.3469C>G; p.P1157A; 17:39408752-39408752	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4362A>T; p.P1454P; 17:39407859-39407859	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.4527C>A; p.D1509E; 17:39407694-39407694	kidney	other; neoplasm	Substitution - Missense
c.1873C>G; p.P625A; 17:39410348-39410348	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.4081G>C; p.D1361H; 17:39408140-39408140	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1784T>C; p.F595S; 17:39410437-39410437	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2521C>T; p.L841F; 17:39409700-39409700	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3869C>A; p.S1290Y; 17:39408352-39408352	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2502A>T; p.P834P; 17:39409719-39409719	central_nervous_system; brain	glioma	Substitution - coding silent
c.4121C>T; p.S1374F; 17:39408100-39408100	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3750A>T; p.G1250G; 17:39408471-39408471	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1280G>T; p.R427I; 17:39419734-39419734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2666G>C; p.S889T; 17:39409555-39409555	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1901C>T; p.S634L; 17:39410320-39410320	skin	malignant_melanoma	Substitution - Missense
c.4179C>T; p.I1393I; 17:39408042-39408042	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1394T>C; p.V465A; 17:39415131-39415131	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.4483G>T; p.E1495*; 17:39407738-39407738	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.678C>G; p.V226V; 17:39427762-39427762	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2798_2808del11; p.I933fs*17; 17:39409413-39409423	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1415C>G; p.S472*; 17:39415110-39415110	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.3265G>A; p.V1089M; 17:39408956-39408956	central_nervous_system; brain	glioma	Substitution - Missense
c.2798_2808del11; p.I933fs*17; 17:39409413-39409423	stomach	adenocarcinoma	Deletion - Frameshift
c.2965G>T; p.D989Y; 17:39409256-39409256	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2865T>C; p.G955G; 17:39409356-39409356	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2865T>C; p.G955G; 17:39409356-39409356	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1156C>T; p.R386*; 17:39419858-39419858	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2959G>A; p.G987R; 17:39409262-39409262	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3744G>A; p.G1248G; 17:39408477-39408477	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2444A>G; p.H815R; 17:39409777-39409777	lung	carcinoma; undifferentiated_carcinoma	Substitution - Missense
c.514A>T; p.K172*; 17:39432003-39432003	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2993C>T; p.T998I; 17:39409228-39409228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3815C>T; p.S1272F; 17:39408406-39408406	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2951C>T; p.S984L; 17:39409270-39409270	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4308C>G; p.I1436M; 17:39407913-39407913	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.4270C>T; p.Q1424*; 17:39407951-39407951	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.73G>A; p.A25T; 17:39447857-39447857	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3192T>C; p.T1064T; 17:39409029-39409029	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.536C>T; p.S179F; 17:39431981-39431981	skin; trunk	malignant_melanoma	Substitution - Missense
c.1410G>T; p.Q470H; 17:39415115-39415115	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3832T>G; p.S1278A; 17:39408389-39408389	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1709delG; p.G570fs*9; 17:39410512-39410512	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1114C>T; p.H372Y; 17:39419900-39419900	liver	carcinoma	Substitution - Missense
c.652C>T; p.H218Y; 17:39427788-39427788	skin	malignant_melanoma	Substitution - Missense
c.4500C>A; p.H1500Q; 17:39407721-39407721	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.3221T>C; p.V1074A; 17:39409000-39409000	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2169C>T; p.I723I; 17:39410052-39410052	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2938A>G; p.N980D; 17:39409283-39409283	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2026C>T; p.P676S; 17:39410195-39410195	NS	NS	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation