| Gene ID | 5320 |
| Symbol | PLA2G2A |
| Synonymous | MOM1|PLA2|PLA2B|PLA2L|PLA2S|PLAS1|sPLA2 |
| Full name | phospholipase A2, group IIA (platelets, synovial fluid) |
| Gene description | GIIC sPLA2|NPS-PLA2|group IIA phospholipase A2|non-pancreatic secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2A|phospholipase A2, membrane associated |
| Cytoband | 1p35 |
| Gene type | protein-coding |
| Synonymous | MIM:172411; HGNC:HGNC:9031; Ensembl:ENSG00000188257; HPRD:01397; Vega:OTTHUMG00000002699 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.55C>T; p.H19Y; 1:19978510-19978510 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.55C>T; p.H19Y; 1:19978510-19978510 |
haematopoietic_and_lymphoid_tissue | haematopoietic_neoplasm; acute_myeloid_leukaemia | Substitution - Missense |
c.101G>A; p.G34E; 1:19978464-19978464 |
skin | malignant_melanoma | Substitution - Missense |
c.385T>C; p.Y129H; 1:19975751-19975751 |
liver | carcinoma | Substitution - Missense |
c.385T>C; p.Y129H; 1:19975751-19975751 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - Missense |
c.112G>A; p.A38T; 1:19978453-19978453 |
liver | carcinoma | Substitution - Missense |
c.148G>A; p.V50M; 1:19978417-19978417 |
skin | malignant_melanoma | Substitution - Missense |
c.153T>G; p.G51G; 1:19978412-19978412 |
thyroid | other; neoplasm | Substitution - coding silent |
c.138C>T; p.C46C; 1:19978427-19978427 |
oesophagus | carcinoma; adenocarcinoma | Substitution - coding silent |
c.34A>T; p.I12F; 1:19978740-19978740 |
lung | carcinoma; small_cell_carcinoma | Substitution - Missense |
c.118A>G; p.S40G; 1:19978447-19978447 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.374A>G; p.Y125C; 1:19975762-19975762 |
thyroid | carcinoma | Substitution - Missense |
c.229C>T; p.R77C; 1:19978078-19978078 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.23C>T; p.A8V; 1:19978751-19978751 |
stomach | carcinoma; intestinal_adenocarcinoma | Substitution - Missense |
c.190T>C; p.C64R; 1:19978117-19978117 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.132C>T; p.Y44Y; 1:19978433-19978433 |
liver | carcinoma; hepatocellular_carcinoma | Substitution - coding silent |
c.132C>T; p.Y44Y; 1:19978433-19978433 |
central_nervous_system; brain | primitive_neuroectodermal_tumour-medulloblastoma; large_cell | Substitution - coding silent |
c.395A>G; p.Y132C; 1:19975741-19975741 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.184C>T; p.R62C; 1:19978381-19978381 |
skin | malignant_melanoma | Substitution - Missense |
c.90G>C; p.K30N; 1:19978475-19978475 |
prostate | carcinoma; adenocarcinoma | Substitution - Missense |
c.373T>A; p.Y125N; 1:19975763-19975763 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.311G>A; p.R104K; 1:19975825-19975825 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.421A>C; p.T141P; 1:19975715-19975715 |
breast | carcinoma | Substitution - Missense |
c.187T>A; p.C63S; 1:19978120-19978120 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.272C>T; p.S91L; 1:19978035-19978035 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.327G>T; p.E109D; 1:19975809-19975809 |
large_intestine; caecum | carcinoma; adenocarcinoma | Substitution - Missense |
c.290G>T; p.C97F; 1:19978017-19978017 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.413G>A; p.R138K; 1:19975723-19975723 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.279C>T; p.S93S; 1:19978028-19978028 |
pancreas | carcinoma; ductal_carcinoma | Substitution - coding silent |