lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5294
Symbol	PIK3CG
Synonymous	PI3CG\|PI3K\|PI3Kgamma\|PIK3\|p110gamma\|p120-PI3K
Full name	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Gene description	1-phosphatidylinositol 3-kinase\|PI3-kinase subunit gamma\|phosphatidylinositol 3 kinase gamma, p110 gamma\|phosphatidylinositol 3-kinase catalytic 110-kD gamma\|phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform\|phosphatidylinosit
Cytoband	7q22.3
Gene type	protein-coding
Synonymous	MIM:601232; HGNC:HGNC:8978; Ensembl:ENSG00000105851; HPRD:03135; Vega:OTTHUMG00000157641

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.2233G>C; p.V745L; 7:106872884-106872884	prostate	carcinoma	Substitution - Missense
c.284A>T; p.H95L; 7:106867845-106867845	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.533G>A; p.R178H; 7:106868094-106868094	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2545C>T; p.R849*; 7:106882123-106882123	liver	carcinoma	Substitution - Nonsense
c.2545C>T; p.R849*; 7:106882123-106882123	liver	carcinoma	Substitution - Nonsense
c.2545C>T; p.R849*; 7:106882123-106882123	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.1346C>T; p.S449F; 7:106868907-106868907	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1333G>A; p.A445T; 7:106868894-106868894	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1325C>T; p.S442F; 7:106868886-106868886	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.388C>T; p.R130W; 7:106867949-106867949	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1005C>T; p.Y335Y; 7:106868566-106868566	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.901G>A; p.E301K; 7:106868462-106868462	skin	malignant_melanoma	Substitution - Missense
c.158G>A; p.S53N; 7:106867719-106867719	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2391+2T>G; p.?; 7:106874805-106874805	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.3129A>T; p.T1043T; 7:106905207-106905207	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1649A>T; p.Q550L; 7:106869210-106869210	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.29T>C; p.V10A; 7:106867590-106867590	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.425C>A; p.P142Q; 7:106867986-106867986	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.715G>A; p.D239N; 7:106868276-106868276	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.955A>T; p.R319W; 7:106868516-106868516	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1422C>T; p.L474L; 7:106868983-106868983	skin	malignant_melanoma	Substitution - coding silent
c.87G>A; p.A29A; 7:106867648-106867648	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1583C>T; p.A528V; 7:106869144-106869144	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1583C>T; p.A528V; 7:106869144-106869144	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2775G>A; p.V925V; 7:106884169-106884169	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3162C>T; p.A1054A; 7:106905240-106905240	lung	carcinoma; undifferentiated_carcinoma	Substitution - coding silent
c.928C>G; p.P310A; 7:106868489-106868489	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1734T>A; p.F578L; 7:106869295-106869295	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.167C>T; p.T56M; 7:106867728-106867728	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3139G>T; p.D1047Y; 7:106905217-106905217	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2918A>G; p.K973R; 7:106886180-106886180	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2936A>G; p.N979S; 7:106886198-106886198	skin; leg	malignant_melanoma	Substitution - Missense
c.2936A>G; p.N979S; 7:106886198-106886198	skin; leg	malignant_melanoma	Substitution - Missense
c.217C>T; p.Q73*; 7:106867778-106867778	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2658G>T; p.T886T; 7:106883061-106883061	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2515C>T; p.R839C; 7:106879642-106879642	pancreas	NS	Substitution - Missense
c.1809T>A; p.I603I; 7:106869370-106869370	kidney	other; neoplasm	Substitution - coding silent
c.2638G>A; p.E880K; 7:106883041-106883041	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2896G>T; p.G966W; 7:106886158-106886158	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2896G>T; p.G966W; 7:106886158-106886158	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2043G>A; p.L681L; 7:106872584-106872584	thyroid	carcinoma	Substitution - coding silent
c.33G>C; p.V11V; 7:106867594-106867594	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2413G>A; p.A805T; 7:106879540-106879540	skin	malignant_melanoma	Substitution - Missense
c.2121A>T; p.R707S; 7:106872772-106872772	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.170C>T; p.A57V; 7:106867731-106867731	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2456A>C; p.D819A; 7:106879583-106879583	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.198C>A; p.N66K; 7:106867759-106867759	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1471G>A; p.G491R; 7:106869032-106869032	skin	malignant_melanoma	Substitution - Missense
c.34C>A; p.L12M; 7:106867595-106867595	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.770C>A; p.S257Y; 7:106868331-106868331	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3152T>C; p.I1051T; 7:106905230-106905230	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1135C>A; p.L379I; 7:106868696-106868696	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3231C>T; p.D1077D; 7:106905309-106905309	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1135C>A; p.L379I; 7:106868696-106868696	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.624G>A; p.P208P; 7:106868185-106868185	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.181G>A; p.V61M; 7:106867742-106867742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.328T>C; p.Y110H; 7:106867889-106867889	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.154A>T; p.K52*; 7:106867715-106867715	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.624G>A; p.P208P; 7:106868185-106868185	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1508C>T; p.T503M; 7:106869069-106869069	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.2667C>A; p.A889A; 7:106883070-106883070	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1312G>T; p.A438S; 7:106868873-106868873	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.115C>A; p.P39T; 7:106867676-106867676	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1621G>A; p.D541N; 7:106869182-106869182	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.844G>C; p.V282L; 7:106868405-106868405	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1621G>A; p.D541N; 7:106869182-106869182	skin	malignant_melanoma	Substitution - Missense
c.2235C>A; p.V745V; 7:106872886-106872886	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.844G>C; p.V282L; 7:106868405-106868405	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.61C>T; p.R21W; 7:106867622-106867622	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.683C>A; p.T228N; 7:106868244-106868244	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.61C>T; p.R21W; 7:106867622-106867622	liver	carcinoma	Substitution - Missense
c.3010C>A; p.P1004T; 7:106886272-106886272	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.61C>T; p.R21W; 7:106867622-106867622	liver	carcinoma	Substitution - Missense
c.73C>T; p.P25S; 7:106867634-106867634	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2971T>G; p.F991V; 7:106886233-106886233	skin	malignant_melanoma	Substitution - Missense
c.533G>T; p.R178L; 7:106868094-106868094	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2802C>T; p.G934G; 7:106884196-106884196	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.516G>T; p.E172D; 7:106868077-106868077	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2022T>G; p.D674E; 7:106872563-106872563	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1905C>A; p.F635L; 7:106869466-106869466	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.146G>A; p.R49H; 7:106867707-106867707	salivary_gland	carcinoma; adenoid_cystic_carcinoma	Substitution - Missense
c.2137T>C; p.F713L; 7:106872788-106872788	skin	malignant_melanoma	Substitution - Missense
c.1054G>A; p.V352M; 7:106868615-106868615	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1630C>A; p.R544R; 7:106869191-106869191	liver	carcinoma	Substitution - coding silent
c.1054G>A; p.V352M; 7:106868615-106868615	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2743delT; p.S915fs*30; 7:106883146-106883146	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1170G>T; p.G390G; 7:106868731-106868731	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1429C>G; p.R477G; 7:106868990-106868990	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.850G>A; p.E284K; 7:106868411-106868411	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.850G>A; p.E284K; 7:106868411-106868411	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1396C>A; p.L466M; 7:106868957-106868957	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1741G>A; p.E581K; 7:106869302-106869302	skin	malignant_melanoma	Substitution - Missense
c.1041G>T; p.E347D; 7:106868602-106868602	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1396C>A; p.L466M; 7:106868957-106868957	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.368G>A; p.R123H; 7:106867929-106867929	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.255G>C; p.A85A; 7:106867816-106867816	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.484G>A; p.V162I; 7:106868045-106868045	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.484G>A; p.V162I; 7:106868045-106868045	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.484G>A; p.V162I; 7:106868045-106868045	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.484G>A; p.V162I; 7:106868045-106868045	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1543T>C; p.S515P; 7:106869104-106869104	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.367C>T; p.R123C; 7:106867928-106867928	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2895C>T; p.F965F; 7:106886157-106886157	endometrium	carcinoma; serous_carcinoma	Substitution - coding silent
c.2895C>T; p.F965F; 7:106886157-106886157	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2583T>A; p.D861E; 7:106882161-106882161	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1038C>T; p.H346H; 7:106868599-106868599	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2895C>T; p.F965F; 7:106886157-106886157	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2895C>T; p.F965F; 7:106886157-106886157	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2895C>T; p.F965F; 7:106886157-106886157	pancreas	carcinoma	Substitution - coding silent
c.3052C>G; p.L1018V; 7:106905130-106905130	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3070A>G; p.T1024A; 7:106905148-106905148	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1365G>A; p.K455K; 7:106868926-106868926	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.3052C>G; p.L1018V; 7:106905130-106905130	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3306C>T; p.A1102A; 7:106905384-106905384	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1842G>A; p.R614R; 7:106869403-106869403	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1365G>T; p.K455N; 7:106868926-106868926	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.3049T>C; p.Y1017H; 7:106905127-106905127	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.121G>A; p.E41K; 7:106867682-106867682	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1779T>C; p.F593F; 7:106869340-106869340	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.408C>G; p.H136Q; 7:106867969-106867969	pleura	pulmonary_blastoma	Substitution - Missense
c.1277G>A; p.G426E; 7:106868838-106868838	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1277G>A; p.G426E; 7:106868838-106868838	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.609G>A; p.T203T; 7:106868170-106868170	skin	malignant_melanoma	Substitution - coding silent
c.1277G>A; p.G426E; 7:106868838-106868838	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.820G>A; p.V274I; 7:106868381-106868381	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.820G>A; p.V274I; 7:106868381-106868381	pancreas	carcinoma	Substitution - Missense
c.1573C>A; p.H525N; 7:106869134-106869134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.820G>A; p.V274I; 7:106868381-106868381	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.820G>A; p.V274I; 7:106868381-106868381	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.549G>A; p.P183P; 7:106868110-106868110	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.76C>T; p.R26C; 7:106867637-106867637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2139C>T; p.F713F; 7:106872790-106872790	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2603G>A; p.G868D; 7:106882181-106882181	skin	malignant_melanoma	Substitution - Missense
c.153C>G; p.C51W; 7:106867714-106867714	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1663T>A; p.L555M; 7:106869224-106869224	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2398A>T; p.K800*; 7:106879525-106879525	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2697G>A; p.T899T; 7:106883100-106883100	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1095C>T; p.I365I; 7:106868656-106868656	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2569A>G; p.T857A; 7:106882147-106882147	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.885C>G; p.H295Q; 7:106868446-106868446	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.234G>A; p.A78A; 7:106867795-106867795	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1325C>A; p.S442Y; 7:106868886-106868886	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3274C>A; p.L1092I; 7:106905352-106905352	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1325C>A; p.S442Y; 7:106868886-106868886	thyroid	other; neoplasm	Substitution - Missense
c.59G>A; p.R20H; 7:106867620-106867620	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2280T>A; p.S760R; 7:106872931-106872931	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1906T>C; p.S636P; 7:106869467-106869467	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.53G>A; p.R18Q; 7:106867614-106867614	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2691C>A; p.G897G; 7:106883094-106883094	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1053C>T; p.T351T; 7:106868614-106868614	pancreas	carcinoma	Substitution - coding silent
c.2546G>A; p.R849Q; 7:106882124-106882124	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1053C>T; p.T351T; 7:106868614-106868614	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.861C>G; p.I287M; 7:106868422-106868422	urinary_tract; bladder	carcinoma	Substitution - Missense
c.465G>A; p.T155T; 7:106868026-106868026	pancreas	NS	Substitution - coding silent
c.2133G>A; p.Q711Q; 7:106872784-106872784	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.861C>G; p.I287M; 7:106868422-106868422	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.53G>A; p.R18Q; 7:106867614-106867614	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.814C>T; p.L272L; 7:106868375-106868375	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1429C>T; p.R477C; 7:106868990-106868990	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2836G>A; p.D946N; 7:106884230-106884230	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1942C>T; p.L648L; 7:106869503-106869503	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1037A>C; p.H346P; 7:106868598-106868598	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.990G>A; p.T330T; 7:106868551-106868551	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3062G>A; p.R1021H; 7:106905140-106905140	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1250G>T; p.S417I; 7:106868811-106868811	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.315G>A; p.Q105Q; 7:106867876-106867876	pancreas	carcinoma	Substitution - coding silent
c.2804A>G; p.Y935C; 7:106884198-106884198	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.3153C>T; p.I1051I; 7:106905231-106905231	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1633G>A; p.A545T; 7:106869194-106869194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.590C>T; p.A197V; 7:106868151-106868151	central_nervous_system; brain	glioma	Substitution - Missense
c.2806T>C; p.C936R; 7:106884200-106884200	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.384G>A; p.T128T; 7:106867945-106867945	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.254C>T; p.A85V; 7:106867815-106867815	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1688C>G; p.P563R; 7:106869249-106869249	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1793G>A; p.W598*; 7:106869354-106869354	skin	malignant_melanoma	Substitution - Nonsense
c.1092G>T; p.K364N; 7:106868653-106868653	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.669C>T; p.V223V; 7:106868230-106868230	skin	malignant_melanoma	Substitution - coding silent
c.1333G>T; p.A445S; 7:106868894-106868894	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1306G>A; p.G436S; 7:106868867-106868867	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.321C>T; p.Y107Y; 7:106867882-106867882	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.908T>G; p.I303S; 7:106868469-106868469	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1124G>A; p.R375Q; 7:106868685-106868685	skin	malignant_melanoma	Substitution - Missense
c.723C>T; p.P241P; 7:106868284-106868284	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.120C>T; p.I40I; 7:106867681-106867681	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.676C>T; p.R226C; 7:106868237-106868237	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.120C>T; p.I40I; 7:106867681-106867681	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.174G>A; p.L58L; 7:106867735-106867735	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1119G>T; p.L373L; 7:106868680-106868680	breast	carcinoma; ER-PR-positive_carcinoma	Substitution - coding silent
c.2288-2A>T; p.?; 7:106874698-106874698	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1168G>T; p.G390W; 7:106868729-106868729	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1230G>A; p.W410*; 7:106868791-106868791	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1168G>T; p.G390W; 7:106868729-106868729	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.160C>A; p.P54T; 7:106867721-106867721	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.258C>T; p.D86D; 7:106867819-106867819	liver	carcinoma	Substitution - coding silent
c.258C>T; p.D86D; 7:106867819-106867819	liver	carcinoma	Substitution - coding silent
c.1112C>T; p.P371L; 7:106868673-106868673	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1531G>A; p.E511K; 7:106869092-106869092	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1531G>A; p.E511K; 7:106869092-106869092	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1028G>A; p.G343D; 7:106868589-106868589	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.588C>T; p.Y196Y; 7:106868149-106868149	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.818G>A; p.R273H; 7:106868379-106868379	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.985T>C; p.C329R; 7:106868546-106868546	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.818G>A; p.R273H; 7:106868379-106868379	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2682C>T; p.S894S; 7:106883085-106883085	pancreas	carcinoid-endocrine_tumour	Substitution - coding silent
c.2471C>A; p.S824*; 7:106879598-106879598	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.2471C>A; p.S824*; 7:106879598-106879598	liver	carcinoma; hepatocellular_carcinoma	Substitution - Nonsense
c.75G>A; p.P25P; 7:106867636-106867636	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - coding silent
c.1190G>A; p.R397K; 7:106868751-106868751	skin	malignant_melanoma	Substitution - Missense
c.2103T>C; p.S701S; 7:106872754-106872754	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1132G>A; p.D378N; 7:106868693-106868693	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2190C>T; p.H730H; 7:106872841-106872841	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.3154C>T; p.R1052W; 7:106905232-106905232	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1335C>A; p.A445A; 7:106868896-106868896	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1647C>A; p.N549K; 7:106869208-106869208	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.389G>A; p.R130Q; 7:106867950-106867950	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.492C>T; p.D164D; 7:106868053-106868053	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2275G>A; p.V759I; 7:106872926-106872926	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2275G>A; p.V759I; 7:106872926-106872926	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1781G>A; p.S594N; 7:106869342-106869342	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2275G>A; p.V759I; 7:106872926-106872926	pancreas	carcinoma	Substitution - Missense
c.1538C>A; p.S513*; 7:106869099-106869099	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2275G>A; p.V759I; 7:106872926-106872926	pancreas	carcinoma	Substitution - Missense
c.2275G>A; p.V759I; 7:106872926-106872926	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2275G>A; p.V759I; 7:106872926-106872926	pancreas	carcinoma	Substitution - Missense
c.2017C>G; p.H673D; 7:106872558-106872558	skin	malignant_melanoma	Substitution - Missense
c.799G>A; p.E267K; 7:106868360-106868360	skin	malignant_melanoma	Substitution - Missense
c.799G>A; p.E267K; 7:106868360-106868360	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2074G>T; p.G692C; 7:106872725-106872725	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.530G>T; p.R177L; 7:106868091-106868091	pancreas	carcinoma	Substitution - Missense
c.799G>A; p.E267K; 7:106868360-106868360	skin	malignant_melanoma	Substitution - Missense
c.1624C>T; p.R542W; 7:106869185-106869185	breast	carcinoma; ER-PR-positive_carcinoma	Substitution - Missense
c.2653G>A; p.A885T; 7:106883056-106883056	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1631G>C; p.R544P; 7:106869192-106869192	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1631G>C; p.R544P; 7:106869192-106869192	breast	carcinoma	Substitution - Missense
c.2653G>A; p.A885T; 7:106883056-106883056	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.674A>C; p.H225P; 7:106868235-106868235	skin	malignant_melanoma	Substitution - Missense
c.1076G>T; p.R359L; 7:106868637-106868637	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.464C>T; p.T155M; 7:106868025-106868025	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.106G>A; p.E36K; 7:106867667-106867667	skin	malignant_melanoma	Substitution - Missense
c.464C>T; p.T155M; 7:106868025-106868025	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.501C>T; p.N167N; 7:106868062-106868062	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1472G>A; p.G491E; 7:106869033-106869033	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1472G>A; p.G491E; 7:106869033-106869033	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1898G>A; p.C633Y; 7:106869459-106869459	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2438T>C; p.L813P; 7:106879565-106879565	central_nervous_system; brain	glioma	Substitution - Missense
c.58C>T; p.R20C; 7:106867619-106867619	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1291C>A; p.L431I; 7:106868852-106868852	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.686C>A; p.T229N; 7:106868247-106868247	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1072G>A; p.D358N; 7:106868633-106868633	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.3028C>T; p.Q1010*; 7:106886290-106886290	skin	malignant_melanoma	Substitution - Nonsense
c.1995+2T>G; p.?; 7:106869558-106869558	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1532A>G; p.E511G; 7:106869093-106869093	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1533G>T; p.E511D; 7:106869094-106869094	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1559T>A; p.L520Q; 7:106869120-106869120	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.982G>A; p.D328N; 7:106868543-106868543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1058C>T; p.S353F; 7:106868619-106868619	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1926C>A; p.A642A; 7:106869487-106869487	liver	carcinoma	Substitution - coding silent
c.174G>T; p.L58L; 7:106867735-106867735	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.740G>C; p.S247T; 7:106868301-106868301	oesophagus	carcinoma	Substitution - Missense
c.849C>T; p.G283G; 7:106868410-106868410	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.174G>T; p.L58L; 7:106867735-106867735	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.849C>T; p.G283G; 7:106868410-106868410	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.573C>T; p.R191R; 7:106868134-106868134	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.849C>T; p.G283G; 7:106868410-106868410	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1306G>C; p.G436R; 7:106868867-106868867	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.573C>T; p.R191R; 7:106868134-106868134	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2060G>C; p.R687T; 7:106872601-106872601	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.1032_1033GG>AA; p.D345N; 7:106868593-106868594	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2069G>T; p.R690I; 7:106872720-106872720	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1321C>T; p.L441L; 7:106868882-106868882	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2069G>T; p.R690I; 7:106872720-106872720	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.777G>T; p.M259I; 7:106868338-106868338	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2157C>T; p.A719A; 7:106872808-106872808	skin	malignant_melanoma	Substitution - coding silent
c.426G>A; p.P142P; 7:106867987-106867987	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1020C>T; p.T340T; 7:106868581-106868581	skin	malignant_melanoma	Substitution - coding silent
c.426G>A; p.P142P; 7:106867987-106867987	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1020C>T; p.T340T; 7:106868581-106868581	skin	malignant_melanoma	Substitution - coding silent
c.897C>T; p.N299N; 7:106868458-106868458	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.426G>A; p.P142P; 7:106867987-106867987	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.575A>G; p.D192G; 7:106868136-106868136	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.502G>A; p.V168M; 7:106868063-106868063	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2850C>T; p.D950D; 7:106884244-106884244	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2252C>T; p.S751L; 7:106872903-106872903	skin	malignant_melanoma	Substitution - Missense
c.2850C>T; p.D950D; 7:106884244-106884244	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.575A>G; p.D192G; 7:106868136-106868136	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2850C>T; p.D950D; 7:106884244-106884244	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.511G>A; p.D171N; 7:106868072-106868072	skin	malignant_melanoma	Substitution - Missense
c.946G>C; p.D316H; 7:106868507-106868507	cervix	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1315C>T; p.P439S; 7:106868876-106868876	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.786C>T; p.P262P; 7:106868347-106868347	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3075C>T; p.N1025N; 7:106905153-106905153	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.292C>T; p.L98L; 7:106867853-106867853	skin	malignant_melanoma	Substitution - coding silent
c.65G>T; p.R22M; 7:106867626-106867626	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1997C>A; p.A666D; 7:106872538-106872538	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.565G>A; p.A189T; 7:106868126-106868126	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.870C>T; p.F290F; 7:106868431-106868431	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.816G>A; p.L272L; 7:106868377-106868377	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1276G>A; p.G426R; 7:106868837-106868837	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.455G>A; p.R152Q; 7:106868016-106868016	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1584C>A; p.A528A; 7:106869145-106869145	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.507C>T; p.H169H; 7:106868068-106868068	central_nervous_system; brain	glioma	Substitution - coding silent
c.507C>T; p.H169H; 7:106868068-106868068	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1551C>T; p.S517S; 7:106869112-106869112	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3071C>A; p.T1024K; 7:106905149-106905149	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2169C>A; p.G723G; 7:106872820-106872820	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2977T>A; p.F993I; 7:106886239-106886239	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2455G>A; p.D819N; 7:106879582-106879582	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.115C>T; p.P39S; 7:106867676-106867676	skin	malignant_melanoma	Substitution - Missense
c.99C>T; p.S33S; 7:106867660-106867660	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.3072A>T; p.T1024T; 7:106905150-106905150	pancreas	carcinoma	Substitution - coding silent
c.2050C>A; p.R684S; 7:106872591-106872591	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2873-1G>A; p.?; 7:106886134-106886134	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.831G>A; p.R277R; 7:106868392-106868392	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1358A>G; p.E453G; 7:106868919-106868919	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1605C>T; p.T535T; 7:106869166-106869166	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2072T>A; p.I691N; 7:106872723-106872723	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2873G>A; p.G958E; 7:106886135-106886135	skin	malignant_melanoma	Substitution - Missense
c.2116T>C; p.S706P; 7:106872767-106872767	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1079A>G; p.K360R; 7:106868640-106868640	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1861G>T; p.A621S; 7:106869422-106869422	stomach	carcinoma	Substitution - Missense
c.1043G>T; p.S348I; 7:106868604-106868604	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1620_1621GG>AA; p.D541N; 7:106869181-106869182	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.142C>A; p.Q48K; 7:106867703-106867703	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2341G>A; p.E781K; 7:106874753-106874753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1271C>T; p.P424L; 7:106868832-106868832	skin	malignant_melanoma	Substitution - Missense
c.2341G>A; p.E781K; 7:106874753-106874753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2407G>T; p.V803L; 7:106879534-106879534	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1550C>T; p.S517F; 7:106869111-106869111	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.27C>A; p.P9P; 7:106867588-106867588	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2421_2422insA; p.P810fs*5; 7:106879548-106879549	oesophagus; lower_third	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2827G>T; p.G943*; 7:106884221-106884221	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.418C>T; p.R140W; 7:106867979-106867979	pancreas	carcinoma; acinar_carcinoma	Substitution - Missense
c.2191G>A; p.D731N; 7:106872842-106872842	skin	malignant_melanoma	Substitution - Missense
c.2191G>A; p.D731N; 7:106872842-106872842	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2965C>T; p.P989S; 7:106886227-106886227	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2362G>A; p.D788N; 7:106874774-106874774	skin	malignant_melanoma	Substitution - Missense
c.468G>A; p.A156A; 7:106868029-106868029	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.876G>A; p.W292*; 7:106868437-106868437	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1440C>T; p.Y480Y; 7:106869001-106869001	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1440C>T; p.Y480Y; 7:106869001-106869001	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.1370A>C; p.K457T; 7:106868931-106868931	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.757G>A; p.A253T; 7:106868318-106868318	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.52C>T; p.R18*; 7:106867613-106867613	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2480C>G; p.T827R; 7:106879607-106879607	pancreas	carcinoma; adenocarcinoma	Substitution - Missense
c.145C>T; p.R49C; 7:106867706-106867706	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.502G>T; p.V168L; 7:106868063-106868063	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.745T>A; p.F249I; 7:106868306-106868306	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.667G>A; p.V223I; 7:106868228-106868228	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.667G>A; p.V223I; 7:106868228-106868228	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.667G>A; p.V223I; 7:106868228-106868228	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3308A>C; p.*1103S; 7:106905386-106905386	large_intestine; colon	carcinoma; adenocarcinoma	Nonstop extension
c.3061C>A; p.R1021S; 7:106905139-106905139	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2428C>A; p.P810T; 7:106879555-106879555	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.3089T>A; p.L1030Q; 7:106905167-106905167	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1614G>A; p.P538P; 7:106869175-106869175	breast	carcinoma	Substitution - coding silent
c.3061C>A; p.R1021S; 7:106905139-106905139	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2454C>T; p.A818A; 7:106879581-106879581	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.17A>G; p.Y6C; 7:106867578-106867578	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2522A>G; p.D841G; 7:106879649-106879649	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.532C>T; p.R178C; 7:106868093-106868093	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.98C>G; p.S33C; 7:106867659-106867659	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1576C>T; p.P526S; 7:106869137-106869137	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1576C>T; p.P526S; 7:106869137-106869137	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1472G>T; p.G491V; 7:106869033-106869033	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2385G>A; p.A795A; 7:106874797-106874797	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1245G>A; p.E415E; 7:106868806-106868806	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.3216C>T; p.I1072I; 7:106905294-106905294	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1339G>A; p.A447T; 7:106868900-106868900	breast	carcinoma	Substitution - Missense
c.1430G>A; p.R477H; 7:106868991-106868991	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1430G>A; p.R477H; 7:106868991-106868991	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2024G>A; p.S675N; 7:106872565-106872565	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1209C>T; p.P403P; 7:106868770-106868770	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1602C>T; p.P534P; 7:106869163-106869163	ovary	other; neoplasm	Substitution - coding silent
c.1701C>T; p.L567L; 7:106869262-106869262	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.3191C>T; p.A1064V; 7:106905269-106905269	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.233C>T; p.A78V; 7:106867794-106867794	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.191A>G; p.H64R; 7:106867752-106867752	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.571C>A; p.R191S; 7:106868132-106868132	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.483C>G; p.D161E; 7:106868044-106868044	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1337C>T; p.S446F; 7:106868898-106868898	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.551G>A; p.R184H; 7:106868112-106868112	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2026G>A; p.A676T; 7:106872567-106872567	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1337C>T; p.S446F; 7:106868898-106868898	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.508G>A; p.D170N; 7:106868069-106868069	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2722A>T; p.N908Y; 7:106883125-106883125	breast	carcinoma	Substitution - Missense
c.1091A>T; p.K364M; 7:106868652-106868652	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.551G>A; p.R184H; 7:106868112-106868112	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1805A>T; p.E602V; 7:106869366-106869366	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2696C>A; p.T899K; 7:106883099-106883099	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2505T>C; p.G835G; 7:106879632-106879632	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1085G>C; p.R362T; 7:106868646-106868646	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2807G>C; p.C936S; 7:106884201-106884201	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2807G>C; p.C936S; 7:106884201-106884201	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.235C>A; p.L79M; 7:106867796-106867796	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3020A>G; p.Q1007R; 7:106886282-106886282	skin	malignant_melanoma	Substitution - Missense
c.1330A>T; p.K444*; 7:106868891-106868891	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.493G>A; p.V165I; 7:106868054-106868054	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2897G>T; p.G966V; 7:106886159-106886159	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2921G>C; p.S974T; 7:106886183-106886183	breast	carcinoma	Substitution - Missense
c.1699C>G; p.L567V; 7:106869260-106869260	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1860T>C; p.S620S; 7:106869421-106869421	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.493G>A; p.V165I; 7:106868054-106868054	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.493G>A; p.V165I; 7:106868054-106868054	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1959C>T; p.D653D; 7:106869520-106869520	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2163G>T; p.L721L; 7:106872814-106872814	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1383C>G; p.L461L; 7:106868944-106868944	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2652C>T; p.D884D; 7:106883055-106883055	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3057C>T; p.A1019A; 7:106905135-106905135	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2996G>A; p.G999E; 7:106886258-106886258	skin	malignant_melanoma	Substitution - Missense
c.3030+1G>T; p.?; 7:106886293-106886293	lung	carcinoma; adenocarcinoma	Unknown
c.28G>A; p.V10M; 7:106867589-106867589	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2652C>T; p.D884D; 7:106883055-106883055	breast	carcinoma	Substitution - coding silent
c.1091A>C; p.K364T; 7:106868652-106868652	skin	malignant_melanoma	Substitution - Missense
c.1413C>A; p.H471Q; 7:106868974-106868974	thyroid	carcinoma	Substitution - Missense
c.1026C>T; p.H342H; 7:106868587-106868587	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.172C>A; p.L58M; 7:106867733-106867733	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.747C>T; p.F249F; 7:106868308-106868308	skin	malignant_melanoma	Substitution - coding silent
c.3052C>T; p.L1018L; 7:106905130-106905130	liver	carcinoma	Substitution - coding silent
c.3217G>A; p.E1073K; 7:106905295-106905295	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3052C>T; p.L1018L; 7:106905130-106905130	liver	carcinoma	Substitution - coding silent
c.251C>T; p.A84V; 7:106867812-106867812	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1859G>T; p.S620I; 7:106869420-106869420	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.251C>T; p.A84V; 7:106867812-106867812	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.251C>T; p.A84V; 7:106867812-106867812	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.251C>T; p.A84V; 7:106867812-106867812	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.251C>T; p.A84V; 7:106867812-106867812	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.819C>T; p.R273R; 7:106868380-106868380	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.819C>T; p.R273R; 7:106868380-106868380	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.819C>T; p.R273R; 7:106868380-106868380	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2925C>T; p.F975F; 7:106886187-106886187	breast	carcinoma	Substitution - coding silent
c.1945G>A; p.E649K; 7:106869506-106869506	skin	malignant_melanoma	Substitution - Missense
c.2658G>A; p.T886T; 7:106883061-106883061	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.330C>T; p.Y110Y; 7:106867891-106867891	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1655G>A; p.R552H; 7:106869216-106869216	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1960G>A; p.D654N; 7:106869521-106869521	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2274C>T; p.D758D; 7:106872925-106872925	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.712G>A; p.D238N; 7:106868273-106868273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.701A>G; p.K234R; 7:106868262-106868262	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.126C>T; p.F42F; 7:106867687-106867687	skin	malignant_melanoma	Substitution - coding silent
c.636G>T; p.W212C; 7:106868197-106868197	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2601T>G; p.Y867*; 7:106882179-106882179	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.126C>T; p.F42F; 7:106867687-106867687	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1473A>G; p.G491G; 7:106869034-106869034	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1671G>A; p.A557A; 7:106869232-106869232	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1671G>A; p.A557A; 7:106869232-106869232	breast	carcinoma; HER-positive_carcinoma	Substitution - coding silent
c.898G>A; p.G300R; 7:106868459-106868459	skin	malignant_melanoma	Substitution - Missense
c.1671G>A; p.A557A; 7:106869232-106869232	skin	malignant_melanoma	Substitution - coding silent
c.798C>T; p.S266S; 7:106868359-106868359	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1671G>A; p.A557A; 7:106869232-106869232	pancreas	NS	Substitution - coding silent
c.2224T>C; p.L742L; 7:106872875-106872875	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1441G>T; p.V481F; 7:106869002-106869002	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1613C>T; p.P538L; 7:106869174-106869174	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3235G>T; p.G1079*; 7:106905313-106905313	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1626G>A; p.R542R; 7:106869187-106869187	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2330C>T; p.S777F; 7:106874742-106874742	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; hairy_cell_leukaemia	Substitution - Missense
c.784C>T; p.P262S; 7:106868345-106868345	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1531G>T; p.E511*; 7:106869092-106869092	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.784C>T; p.P262S; 7:106868345-106868345	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.541G>T; p.V181L; 7:106868102-106868102	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2621A>T; p.D874V; 7:106882199-106882199	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.154A>G; p.K52E; 7:106867715-106867715	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.467C>T; p.A156V; 7:106868028-106868028	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2293T>C; p.S765P; 7:106874705-106874705	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.467C>T; p.A156V; 7:106868028-106868028	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.467C>T; p.A156V; 7:106868028-106868028	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.467C>T; p.A156V; 7:106868028-106868028	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.467C>T; p.A156V; 7:106868028-106868028	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.615G>T; p.K205N; 7:106868176-106868176	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.269G>A; p.R90Q; 7:106867830-106867830	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1717G>A; p.E573K; 7:106869278-106869278	skin	malignant_melanoma	Substitution - Missense
c.3011C>T; p.P1004L; 7:106886273-106886273	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.3023A>T; p.K1008I; 7:106886285-106886285	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3011C>T; p.P1004L; 7:106886273-106886273	skin; face	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.163G>A; p.E55K; 7:106867724-106867724	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2354T>G; p.V785G; 7:106874766-106874766	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1717G>A; p.E573K; 7:106869278-106869278	skin	malignant_melanoma	Substitution - Missense
c.3011C>T; p.P1004L; 7:106886273-106886273	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1273A>C; p.K425Q; 7:106868834-106868834	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2218G>A; p.E740K; 7:106872869-106872869	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.1847T>A; p.V616D; 7:106869408-106869408	breast	carcinoma	Substitution - Missense
c.990G>T; p.T330T; 7:106868551-106868551	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.695C>A; p.T232N; 7:106868256-106868256	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2828G>T; p.G943V; 7:106884222-106884222	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.949G>A; p.E317K; 7:106868510-106868510	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2810T>C; p.V937A; 7:106884204-106884204	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2625A>C; p.K875N; 7:106882203-106882203	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.268C>T; p.R90W; 7:106867829-106867829	stomach	carcinoma	Substitution - Missense
c.268C>T; p.R90W; 7:106867829-106867829	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2528T>A; p.L843H; 7:106879655-106879655	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1199G>T; p.S400I; 7:106868760-106868760	adrenal_gland; adrenal_gland	adrenal_cortical_carcinoma; functioning	Substitution - Missense
c.2528T>A; p.L843H; 7:106879655-106879655	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1039G>A; p.E347K; 7:106868600-106868600	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1203C>G; p.P401P; 7:106868764-106868764	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2107A>T; p.I703L; 7:106872758-106872758	skin	malignant_melanoma	Substitution - Missense
c.1039G>A; p.E347K; 7:106868600-106868600	pancreas	carcinoma	Substitution - Missense
c.212A>T; p.K71M; 7:106867773-106867773	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.727G>A; p.A243T; 7:106868288-106868288	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2988A>G; p.G996G; 7:106886250-106886250	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1334C>T; p.A445V; 7:106868895-106868895	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.527C>T; p.T176M; 7:106868088-106868088	pancreas	carcinoma	Substitution - Missense
c.1852G>A; p.D618N; 7:106869413-106869413	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.12G>T; p.E4D; 7:106867573-106867573	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2941G>C; p.E981Q; 7:106886203-106886203	breast	carcinoma	Substitution - Missense
c.1630C>T; p.R544*; 7:106869191-106869191	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.199G>A; p.V67M; 7:106867760-106867760	liver	carcinoma	Substitution - Missense
c.199G>A; p.V67M; 7:106867760-106867760	liver	carcinoma	Substitution - Missense
c.1076G>A; p.R359H; 7:106868637-106868637	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.617C>T; p.P206L; 7:106868178-106868178	skin	malignant_melanoma	Substitution - Missense
c.3244G>T; p.V1082L; 7:106905322-106905322	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2417C>T; p.S806F; 7:106879544-106879544	lung	carcinoma; small_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation