lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	5284
Symbol	PIGR
Synonymous	-
Full name	polymeric immunoglobulin receptor
Gene description	hepatocellular carcinoma associated protein TB6\|hepatocellular carcinoma-associated protein TB6\|poly-Ig receptor
Cytoband	1q31-q41
Gene type	protein-coding
Synonymous	MIM:173880; HGNC:HGNC:8968; Ensembl:ENSG00000162896; HPRD:01436; Vega:OTTHUMG00000036581

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1562A>C; p.D521A; 1:206934563-206934563	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.857T>C; p.L286P; 1:206937283-206937283	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2131_2132GG>AA; p.G711K; 1:206931679-206931680	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1374C>T; p.I458I; 1:206935490-206935490	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.799G>A; p.A267T; 1:206937341-206937341	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.777G>A; p.L259L; 1:206937363-206937363	liver	carcinoma	Substitution - coding silent
c.1035C>T; p.F345F; 1:206937105-206937105	skin	malignant_melanoma	Substitution - coding silent
c.2209G>A; p.E737K; 1:206930404-206930404	skin	malignant_melanoma	Substitution - Missense
c.777G>A; p.L259L; 1:206937363-206937363	liver	carcinoma	Substitution - coding silent
c.324C>A; p.Y108*; 1:206939183-206939183	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1073_1074delTG; p.V358fs*18; 1:206935790-206935791	stomach	carcinoma; diffuse_adenocarcinoma	Deletion - Frameshift
c.2198G>C; p.R733T; 1:206931498-206931498	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2218G>A; p.E740K; 1:206930395-206930395	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.1061G>A; p.R354H; 1:206935803-206935803	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.1855G>A; p.D619N; 1:206933017-206933017	skin	malignant_melanoma	Substitution - Missense
c.1058C>T; p.P353L; 1:206935806-206935806	skin	malignant_melanoma	Substitution - Missense
c.1774C>T; p.R592W; 1:206933098-206933098	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1774C>T; p.R592W; 1:206933098-206933098	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.683G>T; p.S228I; 1:206937457-206937457	pancreas	pancreatic_intraepithelial_neoplasia_(PanIN)	Substitution - Missense
c.829G>A; p.E277K; 1:206937311-206937311	skin	malignant_melanoma	Substitution - Missense
c.829G>A; p.E277K; 1:206937311-206937311	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.2098G>A; p.A700T; 1:206931713-206931713	skin	malignant_melanoma	Substitution - Missense
c.2249C>T; p.S750F; 1:206930364-206930364	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1963G>T; p.A655S; 1:206932501-206932501	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.721G>A; p.E241K; 1:206937419-206937419	skin	malignant_melanoma	Substitution - Missense
c.1336G>A; p.D446N; 1:206935528-206935528	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1045+1G>T; p.?; 1:206937094-206937094	liver	carcinoma	Unknown
c.1107G>C; p.V369V; 1:206935757-206935757	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.13G>A; p.V5M; 1:206940519-206940519	central_nervous_system; brain	glioma	Substitution - Missense
c.1894G>A; p.E632K; 1:206932570-206932570	skin	malignant_melanoma	Substitution - Missense
c.841G>A; p.V281M; 1:206937299-206937299	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1917G>A; p.A639A; 1:206932547-206932547	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.137C>T; p.S46F; 1:206939370-206939370	breast	carcinoma	Substitution - Missense
c.895C>T; p.L299F; 1:206937245-206937245	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.907G>A; p.D303N; 1:206937233-206937233	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1909T>C; p.S637P; 1:206932555-206932555	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.75C>A; p.P25P; 1:206939432-206939432	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1509C>A; p.C503*; 1:206934616-206934616	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1766C>T; p.S589F; 1:206933106-206933106	oesophagus	carcinoma	Substitution - Missense
c.2285A>G; p.Q762R; 1:206930328-206930328	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.116C>A; p.T39K; 1:206939391-206939391	breast	carcinoma	Substitution - Missense
c.101_102insAA; p.N34fs*33; 1:206939405-206939406	large_intestine	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1747G>C; p.D583H; 1:206933125-206933125	breast	carcinoma	Substitution - Missense
c.569G>A; p.R190K; 1:206937571-206937571	skin	malignant_melanoma	Substitution - Missense
c.569G>A; p.R190K; 1:206937571-206937571	skin	malignant_melanoma	Substitution - Missense
c.184G>A; p.G62S; 1:206939323-206939323	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2051C>T; p.S684L; 1:206931760-206931760	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1731G>T; p.K577N; 1:206933141-206933141	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1395G>T; p.K465N; 1:206934730-206934730	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.262C>T; p.P88S; 1:206939245-206939245	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.613G>A; p.V205I; 1:206937527-206937527	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2124C>T; p.S708S; 1:206931687-206931687	skin	malignant_melanoma	Substitution - coding silent
c.1044G>A; p.E348E; 1:206937096-206937096	liver	carcinoma	Substitution - coding silent
c.1880C>T; p.S627F; 1:206932992-206932992	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2264C>T; p.A755V; 1:206930349-206930349	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1205A>G; p.E402G; 1:206935659-206935659	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.733G>A; p.V245I; 1:206937407-206937407	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2043T>A; p.I681I; 1:206931768-206931768	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1055T>A; p.I352N; 1:206935809-206935809	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.323A>G; p.Y108C; 1:206939184-206939184	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.837_838delTG; p.C279fs*1; 1:206937302-206937303	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1672G>A; p.V558I; 1:206934453-206934453	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1045+10T>A; p.?; 1:206937085-206937085	ovary	other; neoplasm	Unknown
c.1060C>T; p.R354C; 1:206935804-206935804	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2205C>T; p.S735S; 1:206930408-206930408	skin	malignant_melanoma	Substitution - coding silent
c.565G>A; p.G189R; 1:206937575-206937575	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.376G>A; p.E126K; 1:206939131-206939131	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1547C>T; p.A516V; 1:206934578-206934578	skin	malignant_melanoma	Substitution - Missense
c.440C>T; p.T147M; 1:206937700-206937700	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.206C>T; p.S69F; 1:206939301-206939301	skin	malignant_melanoma	Substitution - Missense
c.809T>A; p.L270Q; 1:206937331-206937331	urinary_tract; bladder	carcinoma	Substitution - Missense
c.809T>A; p.L270Q; 1:206937331-206937331	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.146G>A; p.R49Q; 1:206939361-206939361	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2008G>A; p.D670N; 1:206932456-206932456	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.264G>A; p.P88P; 1:206939243-206939243	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1344C>G; p.L448L; 1:206935520-206935520	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2176A>G; p.K726E; 1:206931520-206931520	breast	carcinoma	Substitution - Missense
c.2008G>A; p.D670N; 1:206932456-206932456	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1112G>A; p.C371Y; 1:206935752-206935752	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1334G>A; p.G445D; 1:206935530-206935530	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.597C>T; p.G199G; 1:206937543-206937543	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.829_830insG; p.E277fs*4; 1:206937310-206937311	large_intestine; rectum	carcinoma; adenocarcinoma	Insertion - Frameshift
c.1773T>C; p.F591F; 1:206933099-206933099	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.44-2A>T; p.?; 1:206939465-206939465	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.1773T>C; p.F591F; 1:206933099-206933099	thyroid	other; neoplasm	Substitution - coding silent
c.1992G>C; p.R664R; 1:206932472-206932472	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1513G>T; p.A505S; 1:206934612-206934612	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.870C>T; p.A290A; 1:206937270-206937270	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.406G>T; p.D136Y; 1:206937734-206937734	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2238C>T; p.F746F; 1:206930375-206930375	skin	malignant_melanoma	Substitution - coding silent
c.156G>A; p.R52R; 1:206939351-206939351	skin	malignant_melanoma	Substitution - coding silent
c.1481A>G; p.Y494C; 1:206934644-206934644	breast	carcinoma	Substitution - Missense
c.1587G>T; p.L529L; 1:206934538-206934538	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.197C>T; p.T66I; 1:206939310-206939310	skin	malignant_melanoma	Substitution - Missense
c.1235G>A; p.R412H; 1:206935629-206935629	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.315C>T; p.S105S; 1:206939192-206939192	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1596C>T; p.N532N; 1:206934529-206934529	skin	malignant_melanoma	Substitution - coding silent
c.1165_1166GG>AA; p.G389K; 1:206935698-206935699	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1596C>T; p.N532N; 1:206934529-206934529	skin	malignant_melanoma	Substitution - coding silent
c.624C>G; p.N208K; 1:206937516-206937516	skin	malignant_melanoma	Substitution - Missense
c.486G>A; p.R162R; 1:206937654-206937654	skin	malignant_melanoma	Substitution - coding silent
c.486G>A; p.R162R; 1:206937654-206937654	skin	malignant_melanoma	Substitution - coding silent
c.486G>A; p.R162R; 1:206937654-206937654	skin	malignant_melanoma	Substitution - coding silent
c.1007G>A; p.G336D; 1:206937133-206937133	liver	carcinoma	Substitution - Missense
c.1007G>A; p.G336D; 1:206937133-206937133	liver	carcinoma	Substitution - Missense
c.482A>G; p.K161R; 1:206937658-206937658	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.496T>C; p.Y166H; 1:206937644-206937644	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.2071G>A; p.E691K; 1:206931740-206931740	skin	malignant_melanoma	Substitution - Missense
c.2058C>T; p.F686F; 1:206931753-206931753	pancreas	carcinoma	Substitution - coding silent
c.689A>C; p.K230T; 1:206937451-206937451	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2058C>T; p.F686F; 1:206931753-206931753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2058C>T; p.F686F; 1:206931753-206931753	pancreas	carcinoma	Substitution - coding silent
c.1605C>A; p.T535T; 1:206934520-206934520	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2058C>T; p.F686F; 1:206931753-206931753	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.437G>A; p.R146K; 1:206937703-206937703	skin	malignant_melanoma	Substitution - Missense
c.2216C>T; p.A739V; 1:206930397-206930397	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.168C>T; p.C56C; 1:206939339-206939339	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.860G>A; p.G287E; 1:206937280-206937280	breast	carcinoma	Substitution - Missense
c.815G>A; p.R272Q; 1:206937325-206937325	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1903G>T; p.G635*; 1:206932561-206932561	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Nonsense
c.1053G>A; p.T351T; 1:206935811-206935811	skin	malignant_melanoma	Substitution - coding silent
c.264G>T; p.P88P; 1:206939243-206939243	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1093G>A; p.G365S; 1:206935771-206935771	breast	carcinoma	Substitution - Missense
c.1093G>A; p.G365S; 1:206935771-206935771	thyroid	other; neoplasm	Substitution - Missense
c.117G>A; p.T39T; 1:206939390-206939390	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1859G>A; p.G620E; 1:206933013-206933013	skin	malignant_melanoma	Substitution - Missense
c.948G>A; p.R316R; 1:206937192-206937192	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.742G>C; p.D248H; 1:206937398-206937398	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1185C>T; p.C395C; 1:206935679-206935679	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1357G>A; p.V453M; 1:206935507-206935507	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1595A>T; p.N532I; 1:206934530-206934530	large_intestine; caecum	adenoma	Substitution - Missense
c.1551C>T; p.F517F; 1:206934574-206934574	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2070G>A; p.R690R; 1:206931741-206931741	skin	malignant_melanoma	Substitution - coding silent
c.154C>A; p.R52R; 1:206939353-206939353	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1474G>T; p.E492*; 1:206934651-206934651	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.73C>T; p.P25S; 1:206939434-206939434	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.79G>A; p.E27K; 1:206939428-206939428	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.79G>A; p.E27K; 1:206939428-206939428	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.588G>A; p.Q196Q; 1:206937552-206937552	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.616G>A; p.V206I; 1:206937524-206937524	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.962G>A; p.G321E; 1:206937178-206937178	skin	malignant_melanoma	Substitution - Missense
c.1318T>C; p.W440R; 1:206935546-206935546	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.265G>A; p.E89K; 1:206939242-206939242	skin	malignant_melanoma	Substitution - Missense
c.1981G>A; p.A661T; 1:206932483-206932483	skin	malignant_melanoma	Substitution - Missense
c.145C>T; p.R49W; 1:206939362-206939362	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1981G>A; p.A661T; 1:206932483-206932483	skin	malignant_melanoma	Substitution - Missense
c.2147T>C; p.V716A; 1:206931549-206931549	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1474G>A; p.E492K; 1:206934651-206934651	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1194G>A; p.L398L; 1:206935670-206935670	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1893G>T; p.E631D; 1:206932571-206932571	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.986C>T; p.S329L; 1:206937154-206937154	skin	malignant_melanoma	Substitution - Missense
c.1395G>A; p.K465K; 1:206934730-206934730	skin	malignant_melanoma	Substitution - coding silent
c.1530C>T; p.D510D; 1:206934595-206934595	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2233G>A; p.D745N; 1:206930380-206930380	breast	carcinoma	Substitution - Missense
c.1618G>C; p.G540R; 1:206934507-206934507	eye; uveal_tract	malignant_melanoma; mixed	Substitution - Missense
c.1738G>A; p.A580T; 1:206933134-206933134	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1738G>A; p.A580T; 1:206933134-206933134	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1939_1940insC; p.L647fs*36; 1:206932524-206932525	stomach	carcinoma; diffuse_adenocarcinoma	Insertion - Frameshift
c.1738G>A; p.A580T; 1:206933134-206933134	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.808C>T; p.L270L; 1:206937332-206937332	skin	malignant_melanoma	Substitution - coding silent
c.562_584del23; p.T188fs*30; 1:206937556-206937578	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.2159A>G; p.E720G; 1:206931537-206931537	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1132A>T; p.S378C; 1:206935732-206935732	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.586C>T; p.Q196*; 1:206937554-206937554	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.270C>T; p.N90N; 1:206939237-206939237	stomach	adenocarcinoma	Substitution - coding silent
c.12C>T; p.F4F; 1:206940520-206940520	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2061G>A; p.E687E; 1:206931750-206931750	skin	malignant_melanoma	Substitution - coding silent
c.116C>T; p.T39M; 1:206939391-206939391	prostate	carcinoma	Substitution - Missense
c.1746T>C; p.P582P; 1:206933126-206933126	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1995C>T; p.H665H; 1:206932469-206932469	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.229A>T; p.K77*; 1:206939278-206939278	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1130A>G; p.E377G; 1:206935734-206935734	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2105C>T; p.S702L; 1:206931706-206931706	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1542C>A; p.S514R; 1:206934583-206934583	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1880_1881CC>TT; p.S627F; 1:206932991-206932992	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1189delC; p.L397fs*46; 1:206935675-206935675	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.141C>T; p.V47V; 1:206939366-206939366	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - coding silent
c.569G>T; p.R190I; 1:206937571-206937571	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1473C>G; p.Y491*; 1:206934652-206934652	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.659G>T; p.C220F; 1:206937481-206937481	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.113T>C; p.I38T; 1:206939394-206939394	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1356C>T; p.T452T; 1:206935508-206935508	skin	malignant_melanoma	Substitution - coding silent
c.43+2T>C; p.?; 1:206940487-206940487	ovary	other; neoplasm	Unknown
c.366T>C; p.D122D; 1:206939141-206939141	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1759C>A; p.L587I; 1:206933113-206933113	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1470G>A; p.S490S; 1:206934655-206934655	pancreas	carcinoma; adenocarcinoma	Substitution - coding silent
c.542G>A; p.G181D; 1:206937598-206937598	skin	malignant_melanoma	Substitution - Missense
c.1531G>A; p.E511K; 1:206934594-206934594	skin	malignant_melanoma	Substitution - Missense
c.53C>T; p.T18M; 1:206939454-206939454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1508G>A; p.C503Y; 1:206934617-206934617	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1662G>A; p.E554E; 1:206934463-206934463	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.515A>G; p.Y172C; 1:206937625-206937625	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1375G>A; p.E459K; 1:206935489-206935489	skin	malignant_melanoma	Substitution - Missense
c.1375G>A; p.E459K; 1:206935489-206935489	skin; leg	malignant_melanoma; nodular	Substitution - Missense
c.1801G>A; p.D601N; 1:206933071-206933071	skin	malignant_melanoma	Substitution - Missense
c.1375G>A; p.E459K; 1:206935489-206935489	pancreas	carcinoma	Substitution - Missense
c.2125C>A; p.L709I; 1:206931686-206931686	liver	carcinoma	Substitution - Missense
c.322T>C; p.Y108H; 1:206939185-206939185	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1739C>T; p.A580V; 1:206933133-206933133	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1739C>T; p.A580V; 1:206933133-206933133	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.902C>T; p.P301L; 1:206937238-206937238	skin	malignant_melanoma	Substitution - Missense
c.1739C>T; p.A580V; 1:206933133-206933133	thyroid	other; neoplasm	Substitution - Missense
c.1510C>T; p.Q504*; 1:206934615-206934615	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1810C>T; p.L604F; 1:206933062-206933062	thyroid	carcinoma; papillary_carcinoma	Substitution - Missense
c.1510C>T; p.Q504*; 1:206934615-206934615	lung	carcinoma; adenocarcinoma	Substitution - Nonsense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation