Cancer metastasis database

Annotation category 5

Gene information

Gene ID 51400
Symbol

PPME1

Synonymous

PME-1

Full name

protein phosphatase methylesterase 1

Gene description

protein phosphatase methylesterase-1

Cytoband

11q13.4

Gene type

protein-coding

Synonymous

MIM:611117; HGNC:HGNC:30178; Ensembl:ENSG00000214517; HPRD:17864; Vega:OTTHUMG00000168115

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.403G>A; p.V135I; 11:74230249-74230249

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.157A>T; p.M53L; 11:74203783-74203783

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.1106G>A; p.R369Q; 11:74251679-74251679

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.285C>A; p.F95L; 11:74204442-74204442

 breastcarcinoma; ductal_carcinomaSubstitution - Missense

c.486A>T; p.A162A; 11:74230332-74230332

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.225G>T; p.E75D; 11:74204382-74204382

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.311A>G; p.Q104R; 11:74222334-74222334

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.288G>A; p.T96T; 11:74204445-74204445

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.960G>T; p.L320F; 11:74246201-74246201

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.423C>T; p.A141A; 11:74230269-74230269

 skinmalignant_melanomaSubstitution - coding silent

c.5C>G; p.S2W; 11:74171426-74171426

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.828C>T; p.D276D; 11:74239250-74239250

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.827A>G; p.D276G; 11:74239249-74239249

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.156C>T; p.S52S; 11:74203782-74203782

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.143A>G; p.Q48R; 11:74203769-74203769

 breastcarcinomaSubstitution - Missense

c.28C>A; p.L10I; 11:74171449-74171449

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.1158T>C; p.C386C; 11:74253507-74253507

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.330G>A; p.L110L; 11:74222353-74222353

 livercarcinomaSubstitution - coding silent

c.330G>A; p.L110L; 11:74222353-74222353

 livercarcinomaSubstitution - coding silent

c.337C>T; p.R113*; 11:74222360-74222360

 pancreascarcinomaSubstitution - Nonsense

c.935G>A; p.C312Y; 11:74246176-74246176

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.236T>C; p.L79P; 11:74204393-74204393

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.398+2T>C; p.?; 11:74225258-74225258

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.95G>C; p.R32P; 11:74171516-74171516

 breastcarcinomaSubstitution - Missense

c.338G>A; p.R113Q; 11:74222361-74222361

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.338G>A; p.R113Q; 11:74222361-74222361

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.102-5C>T; p.?; 11:74203723-74203723

 livercarcinomaUnknown

c.369T>C; p.P123P; 11:74225227-74225227

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.485C>T; p.A162V; 11:74230331-74230331

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.116G>A; p.R39Q; 11:74203742-74203742

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.589T>A; p.F197I; 11:74230947-74230947

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1129G>A; p.G377S; 11:74251702-74251702

 pancreascarcinomaSubstitution - Missense

c.1129G>A; p.G377S; 11:74251702-74251702

 pancreascarcinomaSubstitution - Missense

c.1129G>A; p.G377S; 11:74251702-74251702

 pancreascarcinomaSubstitution - Missense

c.287C>T; p.T96M; 11:74204444-74204444

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.214A>T; p.S72C; 11:74204371-74204371

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.975A>G; p.R325R; 11:74247089-74247089

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.1105C>T; p.R369W; 11:74251678-74251678

 pancreascarcinomaSubstitution - Missense

c.733G>A; p.E245K; 11:74239155-74239155

 skinmalignant_melanomaSubstitution - Missense

c.764T>A; p.I255K; 11:74239186-74239186

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.898G>A; p.G300S; 11:74246139-74246139

 pancreascarcinomaSubstitution - Missense

c.898G>A; p.G300S; 11:74246139-74246139

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense