lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	51339
Symbol	DACT1
Synonymous	DAPPER\|DAPPER1\|DPR1\|FRODO\|HDPR1\|THYEX3
Full name	dishevelled-binding antagonist of beta-catenin 1
Gene description	dapper antagonist of catenin 1\|dapper homolog 1\|dapper, antagonist of beta-catenin, homolog 1\|hepatocellular carcinoma novel gene 3 protein\|heptacellular carcinoma novel gene 3
Cytoband	14q23.1
Gene type	protein-coding
Synonymous	MIM:607861; HGNC:HGNC:17748; Ensembl:ENSG00000165617; HPRD:09709; Vega:OTTHUMG00000140324

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.253C>T; p.R85C; 14:58638455-58638455	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2470C>T; p.R824C; 14:58647093-58647093	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.688G>T; p.G230W; 14:58645311-58645311	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2171C>T; p.S724F; 14:58646794-58646794	skin	malignant_melanoma	Substitution - Missense
c.1534delA; p.N513fs*67; 14:58646157-58646157	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.268C>T; p.L90L; 14:58638470-58638470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.268C>T; p.L90L; 14:58638470-58638470	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.268C>T; p.L90L; 14:58638470-58638470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1648G>A; p.E550K; 14:58646271-58646271	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1505T>C; p.V502A; 14:58646128-58646128	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1359delA; p.T455fs*52; 14:58645982-58645982	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.2262C>T; p.F754F; 14:58646885-58646885	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1704G>T; p.R568S; 14:58646327-58646327	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2262C>T; p.F754F; 14:58646885-58646885	skin	malignant_melanoma	Substitution - coding silent
c.1042delA; p.T350fs*4; 14:58645665-58645665	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1732G>A; p.V578I; 14:58646355-58646355	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1732G>A; p.V578I; 14:58646355-58646355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1732G>A; p.V578I; 14:58646355-58646355	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1371G>A; p.K457K; 14:58645994-58645994	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2120C>T; p.A707V; 14:58646743-58646743	liver	carcinoma	Substitution - Missense
c.1656G>A; p.A552A; 14:58646279-58646279	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2120C>T; p.A707V; 14:58646743-58646743	liver	carcinoma	Substitution - Missense
c.1025T>A; p.I342N; 14:58645648-58645648	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1154C>T; p.S385L; 14:58645777-58645777	breast	carcinoma	Substitution - Missense
c.1445C>T; p.S482L; 14:58646068-58646068	skin	malignant_melanoma	Substitution - Missense
c.2286C>T; p.S762S; 14:58646909-58646909	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1154C>T; p.S385L; 14:58645777-58645777	liver	carcinoma	Substitution - Missense
c.2286C>T; p.S762S; 14:58646909-58646909	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1154C>T; p.S385L; 14:58645777-58645777	liver	carcinoma	Substitution - Missense
c.1541G>T; p.S514I; 14:58646164-58646164	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1158G>T; p.Q386H; 14:58645781-58645781	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1760G>A; p.R587H; 14:58646383-58646383	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1143G>T; p.P381P; 14:58645766-58645766	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1737G>A; p.V579V; 14:58646360-58646360	skin	malignant_melanoma	Substitution - coding silent
c.847T>C; p.F283L; 14:58645470-58645470	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1982G>A; p.G661E; 14:58646605-58646605	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2032_2033insG; p.W679fs*44; 14:58646655-58646656	skin	malignant_melanoma	Insertion - Frameshift
c.1551C>T; p.G517G; 14:58646174-58646174	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.709T>C; p.S237P; 14:58645332-58645332	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1906G>T; p.G636C; 14:58646529-58646529	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1551C>T; p.G517G; 14:58646174-58646174	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1472G>T; p.S491I; 14:58646095-58646095	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1551C>T; p.G517G; 14:58646174-58646174	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2390C>T; p.T797M; 14:58647013-58647013	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1264G>T; p.E422*; 14:58645887-58645887	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.938C>A; p.A313D; 14:58645561-58645561	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2384C>T; p.T795M; 14:58647007-58647007	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2384C>T; p.T795M; 14:58647007-58647007	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2385G>A; p.T795T; 14:58647008-58647008	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2384C>T; p.T795M; 14:58647007-58647007	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1571C>T; p.P524L; 14:58646194-58646194	skin	malignant_melanoma	Substitution - Missense
c.1179G>T; p.K393N; 14:58645802-58645802	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1213A>T; p.I405L; 14:58645836-58645836	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.738C>A; p.V246V; 14:58645361-58645361	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2245T>C; p.Y749H; 14:58646868-58646868	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1146C>T; p.G382G; 14:58645769-58645769	prostate	carcinoma	Substitution - coding silent
c.1938C>T; p.P646P; 14:58646561-58646561	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1469C>T; p.P490L; 14:58646092-58646092	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.803G>A; p.R268H; 14:58645426-58645426	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.803G>A; p.R268H; 14:58645426-58645426	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.803G>A; p.R268H; 14:58645426-58645426	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1269A>G; p.S423S; 14:58645892-58645892	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.721T>G; p.F241V; 14:58645344-58645344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2304G>A; p.G768G; 14:58646927-58646927	skin	malignant_melanoma	Substitution - coding silent
c.721T>C; p.F241L; 14:58645344-58645344	skin	malignant_melanoma	Substitution - Missense
c.758A>C; p.K253T; 14:58645381-58645381	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1985G>A; p.R662Q; 14:58646608-58646608	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.165G>A; p.L55L; 14:58638367-58638367	pancreas	carcinoma	Substitution - coding silent
c.1143G>A; p.P381P; 14:58645766-58645766	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.346-1G>T; p.?; 14:58640735-58640735	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1143G>A; p.P381P; 14:58645766-58645766	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1570C>T; p.P524S; 14:58646193-58646193	skin	malignant_melanoma	Substitution - Missense
c.916T>C; p.C306R; 14:58645539-58645539	biliary_tract; gallbladder	carcinoma; adenocarcinoma	Substitution - Missense
c.500G>T; p.G167V; 14:58641613-58641613	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.926C>T; p.S309F; 14:58645549-58645549	skin	malignant_melanoma	Substitution - Missense
c.816A>G; p.P272P; 14:58645439-58645439	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1554delC; p.P520fs*60; 14:58646177-58646177	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1554delC; p.P520fs*60; 14:58646177-58646177	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1554delC; p.P520fs*60; 14:58646177-58646177	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1554delC; p.P520fs*60; 14:58646177-58646177	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1554delC; p.P520fs*60; 14:58646177-58646177	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1554delC; p.P520fs*60; 14:58646177-58646177	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.917G>T; p.C306F; 14:58645540-58645540	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1554delC; p.P520fs*60; 14:58646177-58646177	oesophagus; lower_third	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2364C>T; p.V788V; 14:58646987-58646987	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2415C>T; p.P805P; 14:58647038-58647038	skin	malignant_melanoma	Substitution - coding silent
c.2045C>T; p.S682L; 14:58646668-58646668	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1142C>T; p.P381L; 14:58645765-58645765	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2038A>T; p.K680*; 14:58646661-58646661	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2395C>A; p.P799T; 14:58647018-58647018	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1833G>T; p.K611N; 14:58646456-58646456	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1414G>T; p.G472W; 14:58646037-58646037	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.372T>C; p.G124G; 14:58640762-58640762	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2392G>A; p.A798T; 14:58647015-58647015	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1402G>A; p.A468T; 14:58646025-58646025	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.282G>A; p.A94A; 14:58638484-58638484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1240_1241insC; p.P416fs*35; 14:58645863-58645864	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.2180C>A; p.S727*; 14:58646803-58646803	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1552G>A; p.V518I; 14:58646175-58646175	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1497G>A; p.E499E; 14:58646120-58646120	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.940G>A; p.V314I; 14:58645563-58645563	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2431A>G; p.K811E; 14:58647054-58647054	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.940G>A; p.V314I; 14:58645563-58645563	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.287G>A; p.R96H; 14:58638489-58638489	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2369C>T; p.T790I; 14:58646992-58646992	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1073C>T; p.P358L; 14:58645696-58645696	breast	carcinoma	Substitution - Missense
c.2007T>G; p.P669P; 14:58646630-58646630	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1326C>T; p.G442G; 14:58645949-58645949	pancreas	carcinoma	Substitution - coding silent
c.1326C>T; p.G442G; 14:58645949-58645949	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2017C>G; p.R673G; 14:58646640-58646640	liver	carcinoma	Substitution - Missense
c.2017C>G; p.R673G; 14:58646640-58646640	liver	carcinoma	Substitution - Missense
c.1817G>T; p.R606L; 14:58646440-58646440	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1557C>A; p.P519P; 14:58646180-58646180	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1284C>T; p.A428A; 14:58645907-58645907	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.508G>T; p.G170*; 14:58641621-58641621	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1708C>T; p.H570Y; 14:58646331-58646331	skin	malignant_melanoma	Substitution - Missense
c.297_299delGGA; p.E101delE; 14:58638499-58638501	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - In frame
c.2469C>G; p.L823L; 14:58647092-58647092	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1184C>T; p.S395L; 14:58645807-58645807	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.600C>G; p.T200T; 14:58641713-58641713	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2405A>T; p.H802L; 14:58647028-58647028	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1960G>A; p.G654R; 14:58646583-58646583	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2454C>T; p.L818L; 14:58647077-58647077	skin	malignant_melanoma	Substitution - coding silent
c.2119G>A; p.A707T; 14:58646742-58646742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2119G>A; p.A707T; 14:58646742-58646742	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2396C>A; p.P799Q; 14:58647019-58647019	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1892G>A; p.G631E; 14:58646515-58646515	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2139C>T; p.Y713Y; 14:58646762-58646762	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2139C>T; p.Y713Y; 14:58646762-58646762	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2139C>T; p.Y713Y; 14:58646762-58646762	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.1981G>A; p.G661R; 14:58646604-58646604	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1816C>T; p.R606W; 14:58646439-58646439	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1601A>G; p.E534G; 14:58646224-58646224	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1735G>A; p.V579M; 14:58646358-58646358	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2394C>T; p.A798A; 14:58647017-58647017	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1497G>C; p.E499D; 14:58646120-58646120	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2163T>C; p.A721A; 14:58646786-58646786	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.370G>T; p.G124C; 14:58640760-58640760	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1991C>T; p.A664V; 14:58646614-58646614	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2095C>T; p.R699W; 14:58646718-58646718	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2095C>T; p.R699W; 14:58646718-58646718	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2151C>T; p.Y717Y; 14:58646774-58646774	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2050G>A; p.E684K; 14:58646673-58646673	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1475G>A; p.R492K; 14:58646098-58646098	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1475G>A; p.R492K; 14:58646098-58646098	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2107G>C; p.G703R; 14:58646730-58646730	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.585C>A; p.S195R; 14:58641698-58641698	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1627G>T; p.E543*; 14:58646250-58646250	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1293G>A; p.K431K; 14:58645916-58645916	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.536T>C; p.V179A; 14:58641649-58641649	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2121G>A; p.A707A; 14:58646744-58646744	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2121G>A; p.A707A; 14:58646744-58646744	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2121G>A; p.A707A; 14:58646744-58646744	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1615G>T; p.D539Y; 14:58646238-58646238	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2191G>T; p.E731*; 14:58646814-58646814	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1410G>A; p.G470G; 14:58646033-58646033	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1815G>A; p.T605T; 14:58646438-58646438	pancreas	carcinoma	Substitution - coding silent
c.1815G>A; p.T605T; 14:58646438-58646438	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2247C>T; p.Y749Y; 14:58646870-58646870	breast	carcinoma	Substitution - coding silent
c.1719C>A; p.H573Q; 14:58646342-58646342	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1762G>A; p.G588S; 14:58646385-58646385	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.2172C>T; p.S724S; 14:58646795-58646795	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1011A>C; p.K337N; 14:58645634-58645634	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2046G>A; p.S682S; 14:58646669-58646669	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.786C>T; p.N262N; 14:58645409-58645409	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2048C>A; p.A683D; 14:58646671-58646671	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1087A>T; p.N363Y; 14:58645710-58645710	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1435G>A; p.A479T; 14:58646058-58646058	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.886G>T; p.D296Y; 14:58645509-58645509	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2089G>A; p.G697S; 14:58646712-58646712	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2457G>A; p.K819K; 14:58647080-58647080	skin	malignant_melanoma	Substitution - coding silent
c.2089G>A; p.G697S; 14:58646712-58646712	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2089G>A; p.G697S; 14:58646712-58646712	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1755G>A; p.K585K; 14:58646378-58646378	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.659A>C; p.K220T; 14:58645282-58645282	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2428G>T; p.V810F; 14:58647051-58647051	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2428G>T; p.V810F; 14:58647051-58647051	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1671C>T; p.A557A; 14:58646294-58646294	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.541_544delAGTG; p.E182fs*19; 14:58641654-58641657	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.493A>C; p.S165R; 14:58641606-58641606	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2144G>C; p.S715T; 14:58646767-58646767	kidney	other; neoplasm	Substitution - Missense
c.975T>G; p.S325R; 14:58645598-58645598	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.230G>T; p.G77V; 14:58638432-58638432	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.988T>G; p.S330A; 14:58645611-58645611	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.621C>G; p.C207W; 14:58641734-58641734	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1048A>G; p.T350A; 14:58645671-58645671	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.569G>T; p.S190I; 14:58641682-58641682	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1594G>A; p.V532M; 14:58646217-58646217	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1193C>T; p.A398V; 14:58645816-58645816	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.802C>T; p.R268C; 14:58645425-58645425	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1500C>T; p.N500N; 14:58646123-58646123	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.754C>A; p.P252T; 14:58645377-58645377	skin	malignant_melanoma	Substitution - Missense
c.2191G>A; p.E731K; 14:58646814-58646814	stomach	adenocarcinoma	Substitution - Missense
c.2258G>A; p.C753Y; 14:58646881-58646881	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1083C>T; p.S361S; 14:58645706-58645706	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1985G>C; p.R662P; 14:58646608-58646608	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1555C>T; p.P519S; 14:58646178-58646178	skin	malignant_melanoma	Substitution - Missense
c.1800C>T; p.T600T; 14:58646423-58646423	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2140G>T; p.A714S; 14:58646763-58646763	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1260G>A; p.S420S; 14:58645883-58645883	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1092T>A; p.A364A; 14:58645715-58645715	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1492C>A; p.Q498K; 14:58646115-58646115	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1684G>T; p.G562W; 14:58646307-58646307	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1136G>T; p.R379I; 14:58645759-58645759	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2429T>C; p.V810A; 14:58647052-58647052	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1134C>T; p.V378V; 14:58645757-58645757	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1134C>T; p.V378V; 14:58645757-58645757	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1777G>A; p.G593R; 14:58646400-58646400	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1615G>A; p.D539N; 14:58646238-58646238	lung	carcinoma; non_small_cell_carcinoma	Substitution - Missense
c.1327G>A; p.A443T; 14:58645950-58645950	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.691G>A; p.A231T; 14:58645314-58645314	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1163A>G; p.N388S; 14:58645786-58645786	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.387G>A; p.L129L; 14:58640777-58640777	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1682C>T; p.P561L; 14:58646305-58646305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2023G>A; p.D675N; 14:58646646-58646646	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1142C>A; p.P381Q; 14:58645765-58645765	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1142C>A; p.P381Q; 14:58645765-58645765	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1062G>T; p.R354S; 14:58645685-58645685	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2298C>T; p.F766F; 14:58646921-58646921	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2210_2211CC>TT; p.T737I; 14:58646833-58646834	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.483T>G; p.F161L; 14:58641596-58641596	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>T; p.A277V; 14:58645453-58645453	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.310T>A; p.L104M; 14:58638512-58638512	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1596G>T; p.V532V; 14:58646219-58646219	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2204A>G; p.H735R; 14:58646827-58646827	skin	malignant_melanoma	Substitution - Missense
c.1241C>A; p.S414Y; 14:58645864-58645864	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2029C>T; p.R677W; 14:58646652-58646652	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2029C>T; p.R677W; 14:58646652-58646652	skin	malignant_melanoma	Substitution - Missense
c.704delC; p.L236fs*15; 14:58645327-58645327	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2236C>T; p.Q746*; 14:58646859-58646859	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2236C>T; p.Q746*; 14:58646859-58646859	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation