lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	51284
Symbol	TLR7
Synonymous	TLR7-like
Full name	toll-like receptor 7
Gene description	toll-like receptor 7-like
Cytoband	Xp22.3
Gene type	protein-coding
Synonymous	MIM:300365; HGNC:HGNC:15631; Ensembl:ENSG00000196664; HPRD:02295; Vega:OTTHUMG00000021137

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.644A>G; p.N215S; 23:12886152-12886152	breast	carcinoma	Substitution - Missense
c.1791T>A; p.V597V; 23:12887299-12887299	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1210C>A; p.L404I; 23:12886718-12886718	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.562C>T; p.P188S; 23:12886070-12886070	skin	malignant_melanoma	Substitution - Missense
c.2590T>C; p.F864L; 23:12888098-12888098	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2248C>T; p.R750*; 23:12887756-12887756	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2248C>T; p.R750*; 23:12887756-12887756	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2590T>C; p.F864L; 23:12888098-12888098	kidney	Wilms_tumour	Substitution - Missense
c.3056C>T; p.P1019L; 23:12888564-12888564	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1210C>T; p.L404F; 23:12886718-12886718	breast	carcinoma	Substitution - Missense
c.660T>C; p.P220P; 23:12886168-12886168	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.435C>T; p.G145G; 23:12885943-12885943	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.435C>T; p.G145G; 23:12885943-12885943	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.2795A>G; p.D932G; 23:12888303-12888303	stomach	carcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiable	Substitution - Missense
c.480C>T; p.I160I; 23:12885988-12885988	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.694C>A; p.L232I; 23:12886202-12886202	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.694C>A; p.L232I; 23:12886202-12886202	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1249T>G; p.F417V; 23:12886757-12886757	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.694C>A; p.L232I; 23:12886202-12886202	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>A; p.S277Y; 23:12886338-12886338	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.830C>A; p.S277Y; 23:12886338-12886338	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1750G>A; p.G584R; 23:12887258-12887258	skin	malignant_melanoma	Substitution - Missense
c.2426C>A; p.A809D; 23:12887934-12887934	haematopoietic_and_lymphoid_tissue; lymph_node	lymphoid_neoplasm; follicular_lymphoma	Substitution - Missense
c.208C>T; p.L70F; 23:12885716-12885716	breast	carcinoma	Substitution - Missense
c.194C>T; p.T65M; 23:12885702-12885702	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.194C>T; p.T65M; 23:12885702-12885702	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.961C>T; p.L321L; 23:12886469-12886469	skin	malignant_melanoma	Substitution - coding silent
c.184G>T; p.G62C; 23:12885692-12885692	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.961C>T; p.L321L; 23:12886469-12886469	skin	malignant_melanoma	Substitution - coding silent
c.908A>C; p.Q303P; 23:12886416-12886416	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3040G>C; p.E1014Q; 23:12888548-12888548	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.2478C>A; p.I826I; 23:12887986-12887986	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2294C>T; p.T765I; 23:12887802-12887802	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.723A>G; p.Q241Q; 23:12886231-12886231	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2449C>T; p.P817S; 23:12887957-12887957	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2449C>T; p.P817S; 23:12887957-12887957	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.274G>A; p.V92I; 23:12885782-12885782	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2997G>T; p.K999N; 23:12888505-12888505	skin	malignant_melanoma	Substitution - Missense
c.2603G>T; p.W868L; 23:12888111-12888111	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1204C>A; p.L402I; 23:12886712-12886712	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.813G>A; p.A271A; 23:12886321-12886321	pancreas	carcinoma	Substitution - coding silent
c.616T>C; p.L206L; 23:12886124-12886124	skin	malignant_melanoma	Substitution - coding silent
c.392C>T; p.S131F; 23:12885900-12885900	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2860G>A; p.V954M; 23:12888368-12888368	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.282C>A; p.I94I; 23:12885790-12885790	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.282C>A; p.I94I; 23:12885790-12885790	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.282C>A; p.I94I; 23:12885790-12885790	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1645T>A; p.F549I; 23:12887153-12887153	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1377C>T; p.V459V; 23:12886885-12886885	skin	malignant_melanoma	Substitution - coding silent
c.556C>T; p.R186*; 23:12886064-12886064	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.556C>T; p.R186*; 23:12886064-12886064	skin	malignant_melanoma	Substitution - Nonsense
c.761T>C; p.L254P; 23:12886269-12886269	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2769T>G; p.H923Q; 23:12888277-12888277	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2539A>G; p.I847V; 23:12888047-12888047	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.694C>G; p.L232V; 23:12886202-12886202	lung; middle_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2403G>A; p.T801T; 23:12887911-12887911	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3074T>A; p.F1025Y; 23:12888582-12888582	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1577G>A; p.G526E; 23:12887085-12887085	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2403G>A; p.T801T; 23:12887911-12887911	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2579delG; p.S860fs*19; 23:12888087-12888087	endometrium	carcinoma; serous_carcinoma	Deletion - Frameshift
c.1262A>G; p.K421R; 23:12886770-12886770	liver	carcinoma	Substitution - Missense
c.2614C>T; p.H872Y; 23:12888122-12888122	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1262A>G; p.K421R; 23:12886770-12886770	liver	carcinoma	Substitution - Missense
c.1510A>T; p.S504C; 23:12887018-12887018	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2417C>T; p.P806L; 23:12887925-12887925	skin	malignant_melanoma	Substitution - Missense
c.2015G>A; p.G672D; 23:12887523-12887523	breast	carcinoma	Substitution - Missense
c.1069C>T; p.R357C; 23:12886577-12886577	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.66C>A; p.S22S; 23:12885574-12885574	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2648G>A; p.R883H; 23:12888156-12888156	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.2463G>A; p.K821K; 23:12887971-12887971	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.566G>C; p.C189S; 23:12886074-12886074	central_nervous_system; brain	glioma	Substitution - Missense
c.658C>G; p.P220A; 23:12886166-12886166	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2471G>T; p.S824I; 23:12887979-12887979	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1242C>A; p.L414L; 23:12886750-12886750	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1369C>T; p.P457S; 23:12886877-12886877	skin	malignant_melanoma	Substitution - Missense
c.2810A>T; p.Q937L; 23:12888318-12888318	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2644C>T; p.Q882*; 23:12888152-12888152	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.417A>G; p.L139L; 23:12885925-12885925	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.551A>T; p.Y184F; 23:12886059-12886059	skin	malignant_melanoma	Substitution - Missense
c.2704C>A; p.P902T; 23:12888212-12888212	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1960G>A; p.E654K; 23:12887468-12887468	skin	malignant_melanoma	Substitution - Missense
c.2026A>T; p.N676Y; 23:12887534-12887534	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1998T>C; p.P666P; 23:12887506-12887506	skin	malignant_melanoma	Substitution - coding silent
c.2371G>T; p.A791S; 23:12887879-12887879	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.887G>A; p.R296H; 23:12886395-12886395	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.887G>A; p.R296H; 23:12886395-12886395	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.887G>A; p.R296H; 23:12886395-12886395	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.887G>A; p.R296H; 23:12886395-12886395	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.381T>C; p.T127T; 23:12885889-12885889	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.887G>A; p.R296H; 23:12886395-12886395	pancreas	carcinoma	Substitution - Missense
c.2524C>T; p.L842L; 23:12888032-12888032	skin	malignant_melanoma	Substitution - coding silent
c.1345A>C; p.R449R; 23:12886853-12886853	skin	malignant_melanoma	Substitution - coding silent
c.1507A>T; p.N503Y; 23:12887015-12887015	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2216C>T; p.T739M; 23:12887724-12887724	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1988G>A; p.S663N; 23:12887496-12887496	skin	malignant_melanoma	Substitution - Missense
c.2226T>C; p.F742F; 23:12887734-12887734	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2895A>C; p.E965D; 23:12888403-12888403	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.655G>A; p.V219I; 23:12886163-12886163	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1155G>C; p.L385F; 23:12886663-12886663	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.557G>A; p.R186Q; 23:12886065-12886065	skin	malignant_melanoma	Substitution - Missense
c.557G>A; p.R186Q; 23:12886065-12886065	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2344C>T; p.H782Y; 23:12887852-12887852	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.440C>T; p.P147L; 23:12885948-12885948	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2637G>A; p.K879K; 23:12888145-12888145	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1740T>C; p.F580F; 23:12887248-12887248	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2788G>A; p.E930K; 23:12888296-12888296	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2596G>A; p.D866N; 23:12888104-12888104	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1379T>C; p.L460P; 23:12886887-12886887	liver	carcinoma	Substitution - Missense
c.2184G>A; p.L728L; 23:12887692-12887692	skin	malignant_melanoma	Substitution - coding silent
c.805C>T; p.P269S; 23:12886313-12886313	skin	malignant_melanoma	Substitution - Missense
c.429G>A; p.P143P; 23:12885937-12885937	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1378C>A; p.L460M; 23:12886886-12886886	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.864G>A; p.A288A; 23:12886372-12886372	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2219A>T; p.K740M; 23:12887727-12887727	ovary	other; neoplasm	Substitution - Missense
c.864G>A; p.A288A; 23:12886372-12886372	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1582C>A; p.L528I; 23:12887090-12887090	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2538C>T; p.S846S; 23:12888046-12888046	skin	malignant_melanoma	Substitution - coding silent
c.1729A>C; p.S577R; 23:12887237-12887237	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.271C>A; p.L91M; 23:12885779-12885779	breast	carcinoma	Substitution - Missense
c.2763G>T; p.E921D; 23:12888271-12888271	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1450T>G; p.F484V; 23:12886958-12886958	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1212T>C; p.L404L; 23:12886720-12886720	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.975C>A; p.F325L; 23:12886483-12886483	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.378C>T; p.L126L; 23:12885886-12885886	pancreas	carcinoma	Substitution - coding silent
c.1032A>G; p.Q344Q; 23:12886540-12886540	liver	carcinoma	Substitution - coding silent
c.1168C>T; p.L390F; 23:12886676-12886676	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1032A>G; p.Q344Q; 23:12886540-12886540	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1619C>A; p.P540H; 23:12887127-12887127	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1555C>A; p.L519I; 23:12887063-12887063	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1941G>T; p.K647N; 23:12887449-12887449	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.708G>A; p.M236I; 23:12886216-12886216	breast	carcinoma	Substitution - Missense
c.248C>A; p.A83E; 23:12885756-12885756	urinary_tract; bladder	carcinoma	Substitution - Missense
c.708G>A; p.M236I; 23:12886216-12886216	skin	malignant_melanoma	Substitution - Missense
c.1524C>T; p.V508V; 23:12887032-12887032	pancreas	carcinoma	Substitution - coding silent
c.1524C>T; p.V508V; 23:12887032-12887032	pancreas	carcinoma	Substitution - coding silent
c.1524C>T; p.V508V; 23:12887032-12887032	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.32A>T; p.Q11L; 23:12885540-12885540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1133G>C; p.R378T; 23:12886641-12886641	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1813G>A; p.D605N; 23:12887321-12887321	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.2678C>A; p.A893D; 23:12888186-12888186	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.633G>A; p.L211L; 23:12886141-12886141	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1014T>A; p.F338L; 23:12886522-12886522	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1550C>T; p.S517F; 23:12887058-12887058	NS	malignant_melanoma	Substitution - Missense
c.719T>C; p.I240T; 23:12886227-12886227	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1518T>G; p.F506L; 23:12887026-12887026	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3093C>T; p.N1031N; 23:12888601-12888601	central_nervous_system; brain	glioma	Substitution - coding silent
c.832C>T; p.P278S; 23:12886340-12886340	skin	malignant_melanoma	Substitution - Missense
c.2974G>A; p.E992K; 23:12888482-12888482	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.171A>G; p.T57T; 23:12885679-12885679	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2476A>G; p.I826V; 23:12887984-12887984	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.812C>T; p.A271V; 23:12886320-12886320	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.400C>A; p.L134M; 23:12885908-12885908	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2520G>A; p.L840L; 23:12888028-12888028	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.834C>T; p.P278P; 23:12886342-12886342	skin	malignant_melanoma	Substitution - coding silent
c.654C>T; p.A218A; 23:12886162-12886162	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.2782C>A; p.L928I; 23:12888290-12888290	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2782C>A; p.L928I; 23:12888290-12888290	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1594A>G; p.T532A; 23:12887102-12887102	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.91C>T; p.P31S; 23:12885599-12885599	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.811G>A; p.A271T; 23:12886319-12886319	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2941G>A; p.E981K; 23:12888449-12888449	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.249G>T; p.A83A; 23:12885757-12885757	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2726T>C; p.L909S; 23:12888234-12888234	skin	malignant_melanoma	Substitution - Missense
c.1731C>T; p.S577S; 23:12887239-12887239	pancreas	carcinoma	Substitution - coding silent
c.2402C>T; p.T801M; 23:12887910-12887910	breast	carcinoma	Substitution - Missense
c.685G>T; p.E229*; 23:12886193-12886193	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.508G>T; p.E170*; 23:12886016-12886016	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.3003C>T; p.L1001L; 23:12888511-12888511	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2446G>T; p.G816W; 23:12887954-12887954	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2168G>A; p.R723K; 23:12887676-12887676	skin	malignant_melanoma	Substitution - Missense
c.2252A>C; p.Y751S; 23:12887760-12887760	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2956A>G; p.I986V; 23:12888464-12888464	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1100C>A; p.S367Y; 23:12886608-12886608	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1643A>T; p.D548V; 23:12887151-12887151	urinary_tract; bladder	carcinoma	Substitution - Missense
c.3054C>A; p.N1018K; 23:12888562-12888562	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.3123T>C; p.Y1041Y; 23:12888631-12888631	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.3104C>G; p.T1035R; 23:12888612-12888612	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2217G>A; p.T739T; 23:12887725-12887725	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2214G>A; p.L738L; 23:12887722-12887722	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1372C>A; p.Q458K; 23:12886880-12886880	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1127G>A; p.R376Q; 23:12886635-12886635	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.305C>G; p.P102R; 23:12885813-12885813	skin	malignant_melanoma	Substitution - Missense
c.213C>T; p.T71T; 23:12885721-12885721	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1038_1052del15; p.L347_F351delLSFNF; 23:12886546-12886560	breast	carcinoma	Deletion - In frame
c.760C>A; p.L254I; 23:12886268-12886268	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1245C>A; p.S415R; 23:12886753-12886753	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2229A>T; p.L743L; 23:12887737-12887737	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2362A>G; p.T788A; 23:12887870-12887870	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.43C>T; p.L15F; 23:12885551-12885551	skin; leg	malignant_melanoma	Substitution - Missense
c.43C>T; p.L15F; 23:12885551-12885551	skin; leg	malignant_melanoma	Substitution - Missense
c.2328G>T; p.K776N; 23:12887836-12887836	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1516delT; p.F507fs*16; 23:12887024-12887024	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1516delT; p.F507fs*16; 23:12887024-12887024	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1516delT; p.F507fs*16; 23:12887024-12887024	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2006delT; p.F670fs*8; 23:12887514-12887514	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2204T>G; p.I735S; 23:12887712-12887712	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.457C>T; p.L153F; 23:12885965-12885965	breast	carcinoma	Substitution - Missense
c.2586C>G; p.L862L; 23:12888094-12888094	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2674G>C; p.D892H; 23:12888182-12888182	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1203T>G; p.V401V; 23:12886711-12886711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.103C>T; p.P35S; 23:12885611-12885611	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.89T>A; p.F30Y; 23:12885597-12885597	bone	osteosarcoma	Substitution - Missense
c.86delG; p.W29fs*19; 23:12885594-12885594	meninges	meningioma	Deletion - Frameshift
c.2938G>A; p.D980N; 23:12888446-12888446	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2531C>A; p.S844*; 23:12888039-12888039	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2785G>A; p.E929K; 23:12888293-12888293	skin	malignant_melanoma	Substitution - Missense
c.1019C>A; p.P340H; 23:12886527-12886527	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2934C>T; p.L978L; 23:12888442-12888442	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1806G>A; p.M602I; 23:12887314-12887314	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.44_45delTT; p.F16fs*1; 23:12885552-12885553	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2242C>T; p.Q748*; 23:12887750-12887750	breast	carcinoma	Substitution - Nonsense
c.1457C>A; p.S486Y; 23:12886965-12886965	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.735T>G; p.F245L; 23:12886243-12886243	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation