Cancer metastasis database

Annotation category 5

Gene information

Gene ID 51208
Symbol

CLDN18

Synonymous

SFTA5|SFTPJ

Full name

claudin 18

Gene description

claudin-18|surfactant associated 5|surfactant associated protein J|surfactant, pulmonary associated protein J

Cytoband

3q22.3

Gene type

protein-coding

Synonymous

MIM:609210; HGNC:HGNC:2039; Ensembl:ENSG00000066405; HPRD:13066; Vega:OTTHUMG00000159762

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.262G>T; p.V88F; 3:138023699-138023699

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.58G>A; p.G20S; 3:138010283-138010283

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.697T>A; p.S233T; 3:138031052-138031052

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.697T>A; p.S233T; 3:138031052-138031052

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.232G>A; p.A78T; 3:138023669-138023669

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.145C>T; p.L49F; 3:138010370-138010370

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.162G>A; p.V54V; 3:138010387-138010387

 breastcarcinomaSubstitution - coding silent

c.388C>A; p.L130I; 3:138024609-138024609

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.679G>A; p.A227T; 3:138031034-138031034

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.660C>T; p.Y220Y; 3:138031015-138031015

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.283C>T; p.L95L; 3:138023720-138023720

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.750G>T; p.E250D; 3:138031105-138031105

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.366G>A; p.G122G; 3:138023803-138023803

 skinmalignant_melanomaSubstitution - coding silent

c.750G>T; p.E250D; 3:138031105-138031105

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.391T>G; p.C131G; 3:138024612-138024612

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.45C>T; p.I15I; 3:138010270-138010270

 oesophaguscarcinoma; adenocarcinomaSubstitution - coding silent

c.427C>A; p.L143M; 3:138024648-138024648

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.240A>G; p.R80R; 3:138023677-138023677

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.13A>G; p.T5A; 3:138010238-138010238

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.637G>A; p.A213T; 3:138030992-138030992

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.479G>A; p.G160E; 3:138024700-138024700

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.347A>T; p.N116I; 3:138023784-138023784

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.199T>G; p.F67V; 3:138010424-138010424

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.314G>A; p.R105H; 3:138023751-138023751

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.239G>A; p.R80Q; 3:138023676-138023676

 skinmalignant_melanomaSubstitution - Missense

c.239G>A; p.R80Q; 3:138023676-138023676

 skinmalignant_melanomaSubstitution - Missense

c.704C>A; p.T235N; 3:138031059-138031059

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.657C>A; p.A219A; 3:138031012-138031012

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.238C>T; p.R80*; 3:138023675-138023675

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.238C>T; p.R80*; 3:138023675-138023675

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.273C>T; p.A91A; 3:138023710-138023710

 pancreascarcinomaSubstitution - coding silent

c.393T>C; p.C131C; 3:138024614-138024614

 skinmalignant_melanomaSubstitution - coding silent

c.573G>A; p.M191I; 3:138029866-138029866

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.774C>A; p.H258Q; 3:138031129-138031129

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.664C>A; p.P222T; 3:138031019-138031019

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.504-8C>A; p.?; 3:138029789-138029789

 livercarcinomaUnknown

c.109G>T; p.D37Y; 3:138010334-138010334

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.238C>A; p.R80R; 3:138023675-138023675

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.59G>T; p.G20V; 3:138010284-138010284

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.82G>A; p.D28N; 3:138010307-138010307

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.420C>A; p.A140A; 3:138024641-138024641

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.775G>A; p.D259N; 3:138031130-138031130

 skinmalignant_melanomaSubstitution - Missense

c.689G>A; p.G230D; 3:138031044-138031044

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.672C>T; p.G224G; 3:138031027-138031027

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.748G>A; p.E250K; 3:138031103-138031103

 skinmalignant_melanomaSubstitution - Missense

c.50G>A; p.G17E; 3:138010275-138010275

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.593G>A; p.G198D; 3:138029886-138029886

 breastcarcinomaSubstitution - Missense

c.247A>G; p.M83V; 3:138023684-138023684

 skinmalignant_melanomaSubstitution - Missense

c.629C>A; p.S210Y; 3:138030984-138030984

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.81G>A; p.M27I; 3:138010306-138010306

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.401C>T; p.A134V; 3:138024622-138024622

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.503G>A; p.R168K; 3:138024724-138024724

 skinmalignant_melanomaSubstitution - Missense

c.160G>A; p.V54M; 3:138010385-138010385

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.296T>G; p.F99C; 3:138023733-138023733

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense