lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4953
Symbol	ODC1
Synonymous	ODC
Full name	ornithine decarboxylase 1
Gene description	ornithine decarboxylase
Cytoband	2p25
Gene type	protein-coding
Synonymous	MIM:165640; HGNC:HGNC:8109; Ensembl:ENSG00000115758; HPRD:01324; Vega:OTTHUMG00000090450

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.382G>T; p.V128F; 2:10444162-10444162	central_nervous_system; brain	glioma; oligodendroglioma_Grade_III	Substitution - Missense
c.774G>T; p.A258A; 2:10442151-10442151	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.588C>T; p.F196F; 2:10443568-10443568	skin	malignant_melanoma	Substitution - coding silent
c.1023A>G; p.Q341Q; 2:10441820-10441820	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.213T>G; p.N71K; 2:10444537-10444537	skin	malignant_melanoma	Substitution - Missense
c.1186A>G; p.T396A; 2:10441564-10441564	pancreas	carcinoma	Substitution - Missense
c.1186A>G; p.T396A; 2:10441564-10441564	pancreas	carcinoma	Substitution - Missense
c.1186A>G; p.T396A; 2:10441564-10441564	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.1367C>T; p.S456L; 2:10440743-10440743	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1367C>T; p.S456L; 2:10440743-10440743	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.199G>A; p.A67T; 2:10444551-10444551	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.295C>T; p.Q99*; 2:10444249-10444249	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.171delA; p.A58fs*20; 2:10444579-10444579	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1269C>T; p.P423P; 2:10440841-10440841	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1106G>A; p.R369H; 2:10441644-10441644	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1142T>C; p.M381T; 2:10441608-10441608	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1142T>C; p.M381T; 2:10441608-10441608	stomach	adenocarcinoma	Substitution - Missense
c.57T>C; p.T19T; 2:10444976-10444976	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.706G>T; p.G236C; 2:10443274-10443274	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.567C>T; p.I189I; 2:10443719-10443719	skin	malignant_melanoma	Substitution - coding silent
c.20A>G; p.E7G; 2:10445013-10445013	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.547C>T; p.R183W; 2:10443739-10443739	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.915C>T; p.D305D; 2:10441928-10441928	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.773C>A; p.A258E; 2:10442152-10442152	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.316G>T; p.E106*; 2:10444228-10444228	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.650G>T; p.C217F; 2:10443506-10443506	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.758G>A; p.G253D; 2:10442167-10442167	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.790C>T; p.P264S; 2:10442135-10442135	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.791C>T; p.P264L; 2:10442134-10442134	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.568G>A; p.D190N; 2:10443718-10443718	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1231G>A; p.G411R; 2:10441519-10441519	skin; leg	malignant_melanoma	Substitution - Missense
c.1231G>A; p.G411R; 2:10441519-10441519	skin; leg	malignant_melanoma	Substitution - Missense
c.493C>T; p.R165C; 2:10443793-10443793	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.705C>T; p.G235G; 2:10443275-10443275	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1256A>G; p.Q419R; 2:10440854-10440854	skin	malignant_melanoma	Substitution - Missense
c.159G>A; p.L53L; 2:10444591-10444591	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1307C>T; p.T436I; 2:10440803-10440803	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.21A>C; p.E7D; 2:10445012-10445012	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.21A>C; p.E7D; 2:10445012-10445012	prostate	carcinoma	Substitution - Missense
c.29A>G; p.D10G; 2:10445004-10445004	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.29A>G; p.D10G; 2:10445004-10445004	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.29A>G; p.D10G; 2:10445004-10445004	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1378A>G; p.N460D; 2:10440732-10440732	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1282G>A; p.E428K; 2:10440828-10440828	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.417G>A; p.L139L; 2:10444127-10444127	breast	carcinoma	Substitution - coding silent
c.1270G>A; p.D424N; 2:10440840-10440840	ovary	other; neoplasm	Substitution - Missense
c.1270G>A; p.D424N; 2:10440840-10440840	ovary	other; neoplasm	Substitution - Missense
c.1270G>A; p.D424N; 2:10440840-10440840	ovary	other; neoplasm	Substitution - Missense
c.440C>T; p.P147L; 2:10444104-10444104	skin	malignant_melanoma	Substitution - Missense
c.826G>A; p.G276S; 2:10442099-10442099	soft_tissue; fat	liposarcoma; myxoid-round_cell	Substitution - Missense
c.108T>C; p.D36D; 2:10444642-10444642	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.270T>G; p.A90A; 2:10444480-10444480	liver	carcinoma	Substitution - coding silent
c.811A>G; p.I271V; 2:10442114-10442114	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1285G>A; p.V429I; 2:10440825-10440825	skin	malignant_melanoma	Substitution - Missense
c.460C>T; p.R154W; 2:10443826-10443826	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.460C>T; p.R154W; 2:10443826-10443826	pancreas	carcinoma	Substitution - Missense
c.666+5G>C; p.?; 2:10443485-10443485	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_T_cell_leukaemia	Unknown
c.394A>G; p.T132A; 2:10444150-10444150	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.654T>A; p.V218V; 2:10443502-10443502	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1276C>T; p.P426S; 2:10440834-10440834	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1276C>T; p.P426S; 2:10440834-10440834	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.999C>T; p.H333H; 2:10441844-10441844	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.10T>G; p.F4V; 2:10445023-10445023	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.889T>C; p.L297L; 2:10442036-10442036	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1071A>C; p.G357G; 2:10441679-10441679	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.510C>T; p.F170F; 2:10443776-10443776	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1105C>T; p.R369C; 2:10441645-10441645	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.845C>T; p.S282L; 2:10442080-10442080	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.963C>T; p.G321G; 2:10441880-10441880	central_nervous_system; brain	glioma	Substitution - coding silent
c.1319C>A; p.S440Y; 2:10440791-10440791	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.390G>T; p.M130I; 2:10444154-10444154	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.968A>G; p.Y323C; 2:10441875-10441875	urinary_tract; bladder	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation