Cancer metastasis database

Annotation category 5

Gene information

Gene ID 4922
Symbol

NTS

Synonymous

NMN-125|NN|NT|NT/N|NTS1

Full name

neurotensin

Gene description

neurotensin/neuromedin N|pro-neurotensin/neuromedin

Cytoband

12q21

Gene type

protein-coding

Synonymous

MIM:162650; HGNC:HGNC:8038; Ensembl:ENSG00000133636; HPRD:08878; Vega:OTTHUMG00000169832

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.152T>C; p.V51A; 12:85878361-85878361

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.229G>T; p.E77*; 12:85878438-85878438

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.185G>T; p.C62F; 12:85878394-85878394

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.473G>T; p.R158I; 12:85882335-85882335

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.473G>T; p.R158I; 12:85882335-85882335

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.473G>T; p.R158I; 12:85882335-85882335

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.358G>A; p.E120K; 12:85878567-85878567

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.327A>C; p.K109N; 12:85878536-85878536

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.425G>T; p.R142I; 12:85882287-85882287

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.425G>T; p.R142I; 12:85882287-85882287

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.302T>A; p.M101K; 12:85878511-85878511

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.434C>T; p.P145L; 12:85882296-85882296

 skinmalignant_melanomaSubstitution - Missense

c.494G>T; p.R165I; 12:85882356-85882356

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.494G>T; p.R165I; 12:85882356-85882356

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.494G>T; p.R165I; 12:85882356-85882356

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.496G>T; p.D166Y; 12:85882358-85882358

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.366C>T; p.I122I; 12:85882228-85882228

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.73G>T; p.D25Y; 12:85874476-85874476

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.73G>T; p.D25Y; 12:85874476-85874476

 soft_tissue; striated_musclerhabdomyosarcoma; embryonalSubstitution - Missense

c.73G>T; p.D25Y; 12:85874476-85874476

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - Missense

c.450G>A; p.R150R; 12:85882312-85882312

 skinmalignant_melanomaSubstitution - coding silent

c.280G>T; p.D94Y; 12:85878489-85878489

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.417C>A; p.V139V; 12:85882279-85882279

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.172C>G; p.L58V; 12:85878381-85878381

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.425_426insA; p.I144fs*11; 12:85882287-85882288

 large_intestine; coloncarcinoma; adenocarcinomaInsertion - Frameshift

c.343G>C; p.A115P; 12:85878552-85878552

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.454C>A; p.L152M; 12:85882316-85882316

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.111C>A; p.F37L; 12:85876677-85876677

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.188G>T; p.S63I; 12:85878397-85878397

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.66G>T; p.L22L; 12:85874469-85874469

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.311T>C; p.I104T; 12:85878520-85878520

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.471C>T; p.P157P; 12:85882333-85882333

 NSmalignant_melanomaSubstitution - coding silent

c.471C>T; p.P157P; 12:85882333-85882333

 NSmalignant_melanomaSubstitution - coding silent

c.232G>A; p.V78I; 12:85878441-85878441

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.449G>T; p.R150L; 12:85882311-85882311

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.462G>T; p.E154D; 12:85882324-85882324

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.423G>T; p.K141N; 12:85882285-85882285

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense