lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4919
Symbol	ROR1
Synonymous	NTRKR1\|dJ537F10.1
Full name	receptor tyrosine kinase-like orphan receptor 1
Gene description	neurotrophic tyrosine kinase, receptor-related 1\|tyrosine-protein kinase transmembrane receptor ROR1
Cytoband	1p31.3
Gene type	protein-coding
Synonymous	MIM:602336; HGNC:HGNC:10256; Ensembl:ENSG00000185483; HPRD:03821; Vega:OTTHUMG00000009022

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.349C>T; p.R117W; 1:64049876-64049876	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2764G>A; p.D922N; 1:64178805-64178805	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.351G>T; p.R117R; 1:64049878-64049878	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1768G>A; p.G590R; 1:64177809-64177809	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1335C>T; p.H445H; 1:64159141-64159141	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1521C>A; p.T507T; 1:64177562-64177562	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1768G>A; p.G590R; 1:64177809-64177809	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1098G>A; p.G366G; 1:64142574-64142574	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.442G>A; p.V148I; 1:64049969-64049969	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1579A>C; p.M527L; 1:64177620-64177620	breast	carcinoma	Substitution - Missense
c.1603A>G; p.I535V; 1:64177644-64177644	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.393C>T; p.C131C; 1:64049920-64049920	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.352A>G; p.I118V; 1:64049879-64049879	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1955C>T; p.S652F; 1:64177996-64177996	skin	malignant_melanoma	Substitution - Missense
c.393C>T; p.C131C; 1:64049920-64049920	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.751G>A; p.E251K; 1:64140249-64140249	skin; trunk	malignant_melanoma	Substitution - Missense
c.393C>T; p.C131C; 1:64049920-64049920	central_nervous_system; brain	glioma	Substitution - coding silent
c.2370G>A; p.M790I; 1:64178411-64178411	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1890G>T; p.K630N; 1:64177931-64177931	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2100A>C; p.E700D; 1:64178141-64178141	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1550G>A; p.W517*; 1:64177591-64177591	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.901A>G; p.I301V; 1:64140399-64140399	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.901A>G; p.I301V; 1:64140399-64140399	kidney	carcinoma; renal_cell_carcinoma	Substitution - Missense
c.964C>A; p.R322R; 1:64142440-64142440	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2115G>A; p.V705V; 1:64178156-64178156	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1773delT; p.L593fs*30; 1:64177814-64177814	oesophagus	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2621C>T; p.S874L; 1:64178662-64178662	skin	malignant_melanoma	Substitution - Missense
c.554G>A; p.R185H; 1:64137440-64137440	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.554G>A; p.R185H; 1:64137440-64137440	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.709G>A; p.E237K; 1:64140207-64140207	skin	malignant_melanoma	Substitution - Missense
c.2290G>A; p.G764R; 1:64178331-64178331	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2731A>C; p.K911Q; 1:64178772-64178772	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2423C>T; p.P808L; 1:64178464-64178464	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.565A>G; p.M189V; 1:64137451-64137451	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2590A>G; p.S864G; 1:64178631-64178631	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.14G>C; p.R5P; 1:63774431-63774431	thyroid	other; neoplasm	Substitution - Missense
c.2452C>T; p.P818S; 1:64178493-64178493	skin	malignant_melanoma	Substitution - Missense
c.214G>T; p.G72C; 1:64049741-64049741	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1675delG; p.D559fs*8; 1:64177716-64177716	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1675delG; p.D559fs*8; 1:64177716-64177716	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2148C>T; p.D716D; 1:64178189-64178189	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1251C>T; p.A417A; 1:64159057-64159057	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1080C>T; p.S360S; 1:64142556-64142556	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2197C>T; p.P733S; 1:64178238-64178238	skin	malignant_melanoma	Substitution - Missense
c.893G>A; p.R298Q; 1:64140391-64140391	skin	malignant_melanoma	Substitution - Missense
c.1581G>A; p.M527I; 1:64177622-64177622	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.452G>T; p.G151V; 1:64050686-64050686	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1037C>T; p.T346I; 1:64142513-64142513	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1076A>G; p.H359R; 1:64142552-64142552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1640C>T; p.P547L; 1:64177681-64177681	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2007C>T; p.F669F; 1:64178048-64178048	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2503C>A; p.H835N; 1:64178544-64178544	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.720C>T; p.S240S; 1:64140218-64140218	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1686G>T; p.E562D; 1:64177727-64177727	breast	carcinoma; ductal_carcinoma	Substitution - Missense
c.1684G>A; p.E562K; 1:64177725-64177725	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.482+1G>A; p.?; 1:64050717-64050717	breast	carcinoma	Unknown
c.164-9_182del28; p.?; 1:64049682-64049709	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.572C>A; p.S191Y; 1:64137458-64137458	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.308G>A; p.R103Q; 1:64049835-64049835	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1810G>A; p.E604K; 1:64177851-64177851	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.745C>T; p.R249C; 1:64140243-64140243	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.696C>T; p.F232F; 1:64140194-64140194	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1301C>T; p.S434L; 1:64159107-64159107	breast	carcinoma	Substitution - Missense
c.1158T>A; p.C386*; 1:64142634-64142634	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.264C>T; p.T88T; 1:64049791-64049791	skin	malignant_melanoma	Substitution - coding silent
c.1689C>T; p.F563F; 1:64177730-64177730	skin	malignant_melanoma	Substitution - coding silent
c.2325C>T; p.A775A; 1:64178366-64178366	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.205A>T; p.T69S; 1:64049732-64049732	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1178C>G; p.S393*; 1:64158984-64158984	breast	carcinoma	Substitution - Nonsense
c.994C>T; p.R332C; 1:64142470-64142470	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2240G>A; p.R747Q; 1:64178281-64178281	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.268C>G; p.R90G; 1:64049795-64049795	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2480G>A; p.G827E; 1:64178521-64178521	liver	carcinoma	Substitution - Missense
c.2480G>A; p.G827E; 1:64178521-64178521	liver	carcinoma	Substitution - Missense
c.648T>C; p.S216S; 1:64140146-64140146	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.344G>A; p.R115Q; 1:64049871-64049871	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2181G>A; p.E727E; 1:64178222-64178222	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2181G>A; p.E727E; 1:64178222-64178222	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.547G>A; p.G183S; 1:64137433-64137433	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.748G>C; p.D250H; 1:64140246-64140246	breast	carcinoma	Substitution - Missense
c.2315C>A; p.S772Y; 1:64178356-64178356	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1538A>C; p.N513T; 1:64177579-64177579	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1307C>T; p.S436L; 1:64159113-64159113	breast	carcinoma	Substitution - Missense
c.2766C>T; p.D922D; 1:64178807-64178807	prostate	carcinoma	Substitution - coding silent
c.2490G>A; p.A830A; 1:64178531-64178531	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.557C>T; p.T186I; 1:64137443-64137443	skin	malignant_melanoma	Substitution - Missense
c.1979C>T; p.P660L; 1:64178020-64178020	skin	malignant_melanoma	Substitution - Missense
c.2627C>T; p.S876F; 1:64178668-64178668	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2172C>T; p.L724L; 1:64178213-64178213	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1956C>T; p.S652S; 1:64177997-64177997	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1173C>T; p.C391C; 1:64142649-64142649	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1720G>A; p.G574S; 1:64177761-64177761	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1173C>T; p.C391C; 1:64142649-64142649	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.1429G>A; p.E477K; 1:64177470-64177470	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1051C>T; p.R351C; 1:64142527-64142527	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1051C>T; p.R351C; 1:64142527-64142527	skin; trunk	malignant_melanoma	Substitution - Missense
c.1429G>A; p.E477K; 1:64177470-64177470	skin; trunk	malignant_melanoma	Substitution - Missense
c.547G>T; p.G183C; 1:64137433-64137433	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2098G>T; p.E700*; 1:64178139-64178139	skin	malignant_melanoma	Substitution - Nonsense
c.2812T>A; p.*938K; 1:64178853-64178853	lung	carcinoma; adenocarcinoma	Nonstop extension
c.2348A>C; p.N783T; 1:64178389-64178389	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1004A>G; p.Q335R; 1:64142480-64142480	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2511G>A; p.Q837Q; 1:64178552-64178552	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2327G>A; p.S776N; 1:64178368-64178368	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2327G>A; p.S776N; 1:64178368-64178368	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1608C>A; p.V536V; 1:64177649-64177649	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2229C>T; p.H743H; 1:64178270-64178270	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.450T>G; p.F150L; 1:64049977-64049977	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.448T>C; p.F150L; 1:64049975-64049975	ovary	carcinoma; mucinous_carcinoma	Substitution - Missense
c.448T>C; p.F150L; 1:64049975-64049975	ovary	carcinoma; mucinous_carcinoma	Substitution - Missense
c.1700G>T; p.R567I; 1:64177741-64177741	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1700G>T; p.R567I; 1:64177741-64177741	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1981C>T; p.P661S; 1:64178022-64178022	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1912A>G; p.R638G; 1:64177953-64177953	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1912A>G; p.R638G; 1:64177953-64177953	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.2397G>T; p.Q799H; 1:64178438-64178438	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.762C>T; p.I254I; 1:64140260-64140260	skin	malignant_melanoma	Substitution - coding silent
c.2628C>G; p.S876S; 1:64178669-64178669	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.2236C>A; p.L746I; 1:64178277-64178277	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; plasma_cell_myeloma	Substitution - Missense
c.166T>C; p.S56P; 1:64049693-64049693	skin	malignant_melanoma	Substitution - Missense
c.449T>G; p.F150C; 1:64049976-64049976	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.175A>T; p.T59S; 1:64049702-64049702	breast	carcinoma	Substitution - Missense
c.164-1G>A; p.?; 1:64049690-64049690	skin	malignant_melanoma	Unknown
c.2609G>T; p.S870I; 1:64178650-64178650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2609G>T; p.S870I; 1:64178650-64178650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.706G>A; p.D236N; 1:64140204-64140204	skin	malignant_melanoma	Substitution - Missense
c.2609G>T; p.S870I; 1:64178650-64178650	large_intestine; colon	carcinoma	Substitution - Missense
c.2609G>T; p.S870I; 1:64178650-64178650	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1353A>G; p.V451V; 1:64159159-64159159	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.180C>T; p.L60L; 1:64049707-64049707	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1915G>A; p.E639K; 1:64177956-64177956	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1353A>G; p.V451V; 1:64159159-64159159	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1353A>G; p.V451V; 1:64159159-64159159	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2500G>T; p.A834S; 1:64178541-64178541	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.2500G>T; p.A834S; 1:64178541-64178541	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1692C>T; p.L564L; 1:64177733-64177733	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2381A>G; p.Q794R; 1:64178422-64178422	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.960C>A; p.D320E; 1:64142436-64142436	central_nervous_system; posterior_fossa	glioma; ependymoma	Substitution - Missense
c.425C>T; p.S142F; 1:64049952-64049952	stomach	carcinoma	Substitution - Missense
c.2585C>T; p.S862L; 1:64178626-64178626	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2585C>T; p.S862L; 1:64178626-64178626	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.92-1G>A; p.?; 1:64009304-64009304	skin	malignant_melanoma	Unknown
c.272G>A; p.W91*; 1:64049799-64049799	skin	malignant_melanoma	Substitution - Nonsense
c.1701A>G; p.R567R; 1:64177742-64177742	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.190A>G; p.M64V; 1:64049717-64049717	prostate	adenoma	Substitution - Missense
c.1420C>T; p.R474C; 1:64177461-64177461	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1420C>T; p.R474C; 1:64177461-64177461	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1304C>T; p.S435L; 1:64159110-64159110	skin	malignant_melanoma	Substitution - Missense
c.2007C>A; p.F669L; 1:64178048-64178048	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1170G>T; p.A390A; 1:64142646-64142646	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1492G>A; p.D498N; 1:64177533-64177533	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1037C>G; p.T346S; 1:64142513-64142513	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2373C>T; p.F791F; 1:64178414-64178414	skin	malignant_melanoma	Substitution - coding silent
c.405C>T; p.N135N; 1:64049932-64049932	bone; humerus	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.768G>A; p.E256E; 1:64140266-64140266	skin	malignant_melanoma	Substitution - coding silent
c.2767G>T; p.A923S; 1:64178808-64178808	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1624G>A; p.V542I; 1:64177665-64177665	breast	carcinoma	Substitution - Missense
c.206C>T; p.T69M; 1:64049733-64049733	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.206C>T; p.T69M; 1:64049733-64049733	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.206C>T; p.T69M; 1:64049733-64049733	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.206C>T; p.T69M; 1:64049733-64049733	breast	carcinoma	Substitution - Missense
c.2577C>G; p.A859A; 1:64178618-64178618	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.431G>A; p.G144E; 1:64049958-64049958	skin	malignant_melanoma	Substitution - Missense
c.431G>A; p.G144E; 1:64049958-64049958	skin	malignant_melanoma	Substitution - Missense
c.2667A>G; p.S889S; 1:64178708-64178708	ovary	carcinoma; mucinous_carcinoma	Substitution - coding silent
c.2667A>G; p.S889S; 1:64178708-64178708	ovary	carcinoma; mucinous_carcinoma	Substitution - coding silent
c.323G>A; p.R108Q; 1:64049850-64049850	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.807A>G; p.S269S; 1:64140305-64140305	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1229C>T; p.P410L; 1:64159035-64159035	skin; ear	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2126A>C; p.Q709P; 1:64178167-64178167	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.865G>C; p.E289Q; 1:64140363-64140363	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1969C>T; p.R657C; 1:64178010-64178010	breast	carcinoma	Substitution - Missense
c.261C>A; p.P87P; 1:64049788-64049788	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2326A>G; p.S776G; 1:64178367-64178367	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1724G>A; p.C575Y; 1:64177765-64177765	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.350G>T; p.R117L; 1:64049877-64049877	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2665T>C; p.S889P; 1:64178706-64178706	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2665T>C; p.S889P; 1:64178706-64178706	liver	carcinoma	Substitution - Missense
c.2765A>G; p.D922G; 1:64178806-64178806	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.427A>G; p.T143A; 1:64049954-64049954	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2665T>C; p.S889P; 1:64178706-64178706	liver	carcinoma	Substitution - Missense
c.322C>T; p.R108W; 1:64049849-64049849	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1699A>G; p.R567G; 1:64177740-64177740	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1699A>G; p.R567G; 1:64177740-64177740	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1278C>T; p.C426C; 1:64159084-64159084	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1073G>A; p.G358D; 1:64142549-64142549	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.989C>T; p.S330L; 1:64142465-64142465	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2322T>G; p.S774R; 1:64178363-64178363	pancreas	carcinoma	Substitution - Missense
c.1855C>T; p.R619C; 1:64177896-64177896	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1217A>G; p.Y406C; 1:64159023-64159023	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1553C>T; p.T518M; 1:64177594-64177594	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1553C>T; p.T518M; 1:64177594-64177594	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1553C>T; p.T518M; 1:64177594-64177594	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.973G>A; p.V325I; 1:64142449-64142449	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.103T>G; p.S35A; 1:64009316-64009316	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.673C>T; p.P225S; 1:64140171-64140171	skin	malignant_melanoma	Substitution - Missense
c.1368G>A; p.L456L; 1:64159174-64159174	breast	carcinoma; HER-positive_carcinoma	Substitution - coding silent
c.748G>A; p.D250N; 1:64140246-64140246	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2616C>T; p.P872P; 1:64178657-64178657	skin	malignant_melanoma	Substitution - coding silent
c.1887A>G; p.V629V; 1:64177928-64177928	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2021_2022delAT; p.I675fs*23; 1:64178062-64178063	breast	carcinoma; basal_(triple-negative)_carcinoma	Deletion - Frameshift
c.993G>A; p.G331G; 1:64142469-64142469	skin	malignant_melanoma	Substitution - coding silent
c.1361C>T; p.S454L; 1:64159167-64159167	skin	malignant_melanoma	Substitution - Missense
c.2210C>T; p.P737L; 1:64178251-64178251	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2088C>T; p.F696F; 1:64178129-64178129	breast	carcinoma	Substitution - coding silent
c.1468G>A; p.G490S; 1:64177509-64177509	central_nervous_system; medulla	primitive_neuroectodermal_tumour-medulloblastoma; classic	Substitution - Missense
c.2127G>T; p.Q709H; 1:64178168-64178168	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.589G>A; p.E197K; 1:64137475-64137475	skin; mucosal	malignant_melanoma	Substitution - Missense
c.781C>T; p.Q261*; 1:64140279-64140279	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.2420G>T; p.G807V; 1:64178461-64178461	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2666C>T; p.S889L; 1:64178707-64178707	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2796G>A; p.M932I; 1:64178837-64178837	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1208A>G; p.E403G; 1:64159014-64159014	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2204G>A; p.R735K; 1:64178245-64178245	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1174G>A; p.D392N; 1:64142650-64142650	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.226G>T; p.E76*; 1:64049753-64049753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1634A>T; p.E545V; 1:64177675-64177675	liver	carcinoma	Substitution - Missense
c.1927G>A; p.A643T; 1:64177968-64177968	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation