Cancer metastasis database

Annotation category 5

Gene information

Gene ID 4831
Symbol

NME2

Synonymous

NDKB|NDPK-B|NDPKB|NM23-H2|NM23B|PUF

Full name

NME/NM23 nucleoside diphosphate kinase 2

Gene description

HEL-S-155an|NDP kinase B|c-myc purine-binding transcription factor PUF|c-myc transcription factor|epididymis secretory sperm binding protein Li 155an|histidine protein kinase NDKB|non-metastatic cells 2, protein (NM23) expressed in|non-metastatic cells 2,

Cytoband

17q21.3

Gene type

protein-coding

Synonymous

MIM:156491; HGNC:HGNC:7850; Ensembl:ENSG00000011052; Ensembl:ENSG00000243678; HPRD:01132; Vega:OTTHUMG00000154062

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.150G>A; p.Q50Q; 17:51168265-51168265

lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.210A>G; p.S70S; 17:51168325-51168325

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.313C>T; p.R105C; 17:51170021-51170021

oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.436G>T; p.A146S; 17:51171581-51171581

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.412G>T; p.E138*; 17:51171557-51171557

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.173G>A; p.R58Q; 17:51168288-51168288

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.229G>A; p.V77I; 17:51169937-51169937

skin; trunkmalignant_melanomaSubstitution - Missense

c.437C>T; p.A146V; 17:51171582-51171582

haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.314G>A; p.R105H; 17:51170022-51170022

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.342-2A>G; p.?; 17:51171485-51171485

livercarcinomaUnknown

c.246C>T; p.N82N; 17:51169954-51169954

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.2T>C; p.M1T; 17:51166832-51166832

large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.139C>A; p.H47N; 17:51168254-51168254

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.385G>T; p.E129*; 17:51171530-51171530

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.17G>T; p.R6L; 17:51166847-51166847

upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.247G>A; p.V83M; 17:51169955-51169955

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.247G>A; p.V83M; 17:51169955-51169955

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense