lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4772
Symbol	NFATC1
Synonymous	NF-ATC\|NFAT2\|NFATc
Full name	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Gene description	NFAT transcription complex cytosolic component\|nuclear factor of activated T-cells, cytoplasmic 1
Cytoband	18q23
Gene type	protein-coding
Synonymous	MIM:600489; HGNC:HGNC:7775; Ensembl:ENSG00000131196; HPRD:02729; Vega:OTTHUMG00000132897

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.826G>A; p.G276S; 18:79411140-79411140	thyroid	carcinoma	Substitution - Missense
c.1310C>G; p.A437G; 18:79433701-79433701	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1820A>T; p.N607I; 18:79451772-79451772	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2609G>A; p.R870H; 18:79486803-79486803	oesophagus; lower_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.616G>A; p.E206K; 18:79410930-79410930	skin	malignant_melanoma	Substitution - Missense
c.697G>A; p.V233I; 18:79411011-79411011	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1920+1G>T; p.?; 18:79461367-79461367	lung	carcinoma; adenocarcinoma	Unknown
c.1333C>A; p.H445N; 18:79433724-79433724	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2754A>G; p.I918M; 18:79527538-79527538	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.229G>A; p.G77R; 18:79410543-79410543	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.397C>T; p.P133S; 18:79410711-79410711	skin	malignant_melanoma	Substitution - Missense
c.1002G>A; p.A334A; 18:79411316-79411316	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.684G>T; p.S228S; 18:79410998-79410998	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1702G>T; p.A568S; 18:79451105-79451105	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.136C>T; p.P46S; 18:79410450-79410450	NS	malignant_melanoma	Substitution - Missense
c.1587C>T; p.S529S; 18:79450990-79450990	breast	carcinoma	Substitution - coding silent
c.554C>T; p.A185V; 18:79410868-79410868	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.981G>C; p.L327L; 18:79411295-79411295	pancreas	carcinoma	Substitution - coding silent
c.422C>T; p.T141M; 18:79410736-79410736	breast	carcinoma	Substitution - Missense
c.981G>C; p.L327L; 18:79411295-79411295	pancreas	carcinoma; ductal_carcinoma	Substitution - coding silent
c.981G>C; p.L327L; 18:79411295-79411295	pancreas	carcinoma	Substitution - coding silent
c.422C>T; p.T141M; 18:79410736-79410736	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1764G>A; p.Q588Q; 18:79451716-79451716	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.830C>T; p.S277F; 18:79411144-79411144	skin	malignant_melanoma	Substitution - Missense
c.774C>T; p.N258N; 18:79411088-79411088	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2743G>A; p.V915I; 18:79486937-79486937	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1430C>G; p.A477G; 18:79448864-79448864	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1887G>A; p.M629I; 18:79461333-79461333	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1368T>A; p.N456K; 18:79448802-79448802	liver	carcinoma	Substitution - Missense
c.1292C>T; p.T431M; 18:79433683-79433683	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1292C>T; p.T431M; 18:79433683-79433683	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.660C>T; p.S220S; 18:79410974-79410974	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.201C>T; p.I67I; 18:79410515-79410515	skin	malignant_melanoma	Substitution - coding silent
c.1052C>G; p.A351G; 18:79411366-79411366	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1302C>T; p.S434S; 18:79433693-79433693	stomach	adenocarcinoma	Substitution - coding silent
c.1662C>T; p.H554H; 18:79451065-79451065	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.2009G>T; p.R670I; 18:79467538-79467538	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.206C>T; p.P69L; 18:79410520-79410520	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.904G>A; p.A302T; 18:79411218-79411218	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.779G>T; p.R260L; 18:79411093-79411093	urinary_tract; bladder	carcinoma	Substitution - Missense
c.243C>T; p.D81D; 18:79410557-79410557	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2241G>A; p.A747A; 18:79486435-79486435	thyroid	other; neoplasm	Substitution - coding silent
c.2630C>A; p.A877D; 18:79486824-79486824	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.224G>T; p.G75V; 18:79410538-79410538	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.821C>T; p.P274L; 18:79411135-79411135	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1848C>T; p.F616F; 18:79451800-79451800	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1717G>T; p.E573*; 18:79451120-79451120	lung	carcinoma; small_cell_carcinoma	Substitution - Nonsense
c.2052C>T; p.N684N; 18:79467581-79467581	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1983C>T; p.V661V; 18:79467512-79467512	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.332C>T; p.S111L; 18:79410646-79410646	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1613C>T; p.T538M; 18:79451016-79451016	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1549G>A; p.V517I; 18:79448983-79448983	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.433A>C; p.S145R; 18:79410747-79410747	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.812C>T; p.T271M; 18:79411126-79411126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1905G>T; p.R635R; 18:79461351-79461351	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.836G>A; p.R279Q; 18:79411150-79411150	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1656C>T; p.R552R; 18:79451059-79451059	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1216_1217delCT; p.L406fs*8; 18:79433607-79433608	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.738C>T; p.P246P; 18:79411052-79411052	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2212T>G; p.C738G; 18:79486406-79486406	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1904G>A; p.R635Q; 18:79461350-79461350	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1800G>A; p.K600K; 18:79451752-79451752	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - coding silent
c.2212T>G; p.C738G; 18:79486406-79486406	breast	carcinoma	Substitution - Missense
c.2212T>G; p.C738G; 18:79486406-79486406	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1279G>A; p.A427T; 18:79433670-79433670	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2336A>G; p.Q779R; 18:79486530-79486530	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1136A>C; p.H379P; 18:79411450-79411450	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.747T>G; p.P249P; 18:79411061-79411061	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.776G>T; p.G259V; 18:79411090-79411090	liver	carcinoma	Substitution - Missense
c.1947A>G; p.P649P; 18:79467476-79467476	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.747T>G; p.P249P; 18:79411061-79411061	thyroid	other; neoplasm	Substitution - coding silent
c.1992C>T; p.Y664Y; 18:79467521-79467521	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.747T>G; p.P249P; 18:79411061-79411061	thyroid	other; neoplasm	Substitution - coding silent
c.776G>T; p.G259V; 18:79411090-79411090	liver	carcinoma	Substitution - Missense
c.481G>A; p.A161T; 18:79410795-79410795	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.602C>T; p.T201I; 18:79410916-79410916	skin; hand	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1920G>A; p.P640P; 18:79461366-79461366	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.807G>A; p.S269S; 18:79411121-79411121	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1543C>T; p.R515*; 18:79448977-79448977	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2208G>A; p.P736P; 18:79486402-79486402	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1483G>A; p.E495K; 18:79448917-79448917	skin	malignant_melanoma	Substitution - Missense
c.2346A>G; p.G782G; 18:79486540-79486540	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.2738A>G; p.D913G; 18:79486932-79486932	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2783C>T; p.T928I; 18:79527567-79527567	skin	malignant_melanoma	Substitution - Missense
c.161delC; p.P55fs*55; 18:79410475-79410475	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.2564G>T; p.C855F; 18:79486758-79486758	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1328G>A; p.G443E; 18:79433719-79433719	skin	malignant_melanoma	Substitution - Missense
c.284G>A; p.R95K; 18:79410598-79410598	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2164G>A; p.A722T; 18:79486358-79486358	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1221G>A; p.P407P; 18:79433612-79433612	pancreas	carcinoma	Substitution - coding silent
c.295G>A; p.A99T; 18:79410609-79410609	large_intestine; caecum	adenoma	Substitution - Missense
c.1247G>A; p.R416Q; 18:79433638-79433638	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2014C>T; p.R672*; 18:79467543-79467543	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.383T>A; p.V128E; 18:79410697-79410697	central_nervous_system; brain	glioma	Substitution - Missense
c.631G>A; p.G211R; 18:79410945-79410945	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2101A>C; p.T701P; 18:79486295-79486295	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1828C>T; p.Q610*; 18:79451780-79451780	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.685C>T; p.P229S; 18:79410999-79410999	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.154C>T; p.L52L; 18:79410468-79410468	skin	malignant_melanoma	Substitution - coding silent
c.203C>T; p.P68L; 18:79410517-79410517	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2193C>T; p.L731L; 18:79486387-79486387	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1190C>T; p.P397L; 18:79433581-79433581	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1053C>T; p.A351A; 18:79411367-79411367	prostate	carcinoma	Substitution - coding silent
c.1691C>T; p.S564F; 18:79451094-79451094	skin	malignant_melanoma	Substitution - Missense
c.1786G>A; p.V596M; 18:79451738-79451738	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1310C>T; p.A437V; 18:79433701-79433701	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.131C>T; p.P44L; 18:79410445-79410445	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.787C>G; p.P263A; 18:79411101-79411101	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.322G>A; p.E108K; 18:79410636-79410636	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.825C>T; p.H275H; 18:79411139-79411139	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2030G>A; p.R677H; 18:79467559-79467559	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1147T>G; p.W383G; 18:79411461-79411461	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.209C>T; p.A70V; 18:79410523-79410523	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2762A>G; p.N921S; 18:79527546-79527546	liver	carcinoma	Substitution - Missense
c.890C>T; p.S297L; 18:79411204-79411204	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.666G>T; p.R222R; 18:79410980-79410980	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1907A>T; p.D636V; 18:79461353-79461353	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2001C>T; p.N667N; 18:79467530-79467530	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.852C>T; p.D284D; 18:79411166-79411166	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2568G>A; p.P856P; 18:79486762-79486762	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2568G>A; p.P856P; 18:79486762-79486762	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1634C>T; p.T545I; 18:79451037-79451037	pancreas	carcinoma	Substitution - Missense
c.520T>G; p.S174A; 18:79410834-79410834	skin	malignant_melanoma	Substitution - Missense
c.219C>T; p.P73P; 18:79410533-79410533	skin	malignant_melanoma	Substitution - coding silent
c.1425G>A; p.P475P; 18:79448859-79448859	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.2041C>T; p.L681F; 18:79467570-79467570	skin	malignant_melanoma	Substitution - Missense
c.1323G>A; p.S441S; 18:79433714-79433714	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2239G>A; p.A747T; 18:79486433-79486433	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.169C>T; p.H57Y; 18:79410483-79410483	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.124delG; p.A42fs*68; 18:79410438-79410438	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Deletion - Frameshift
c.1620C>T; p.I540I; 18:79451023-79451023	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1620C>T; p.I540I; 18:79451023-79451023	skin	malignant_melanoma	Substitution - coding silent
c.298C>T; p.P100S; 18:79410612-79410612	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.132G>T; p.P44P; 18:79410446-79410446	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2125delT; p.L709fs*1; 18:79486319-79486319	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.2690C>T; p.P897L; 18:79486884-79486884	skin	malignant_melanoma	Substitution - Missense
c.1818C>A; p.H606Q; 18:79451770-79451770	breast	carcinoma	Substitution - Missense
c.664C>T; p.R222W; 18:79410978-79410978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1158_1159insA; p.P388fs*27; 18:79411472-79411473	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Insertion - Frameshift
c.460G>C; p.D154H; 18:79410774-79410774	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.870C>A; p.N290K; 18:79411184-79411184	endometrium	carcinoma; serous_carcinoma	Substitution - Missense
c.1476C>T; p.T492T; 18:79448910-79448910	prostate	carcinoma	Substitution - coding silent
c.2755A>T; p.I919L; 18:79527539-79527539	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.391G>A; p.V131I; 18:79410705-79410705	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2776A>G; p.T926A; 18:79527560-79527560	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.552C>T; p.Y184Y; 18:79410866-79410866	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1686G>A; p.T562T; 18:79451089-79451089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1812T>C; p.S604S; 18:79451764-79451764	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1808T>C; p.L603P; 18:79451760-79451760	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.115G>A; p.V39I; 18:79410429-79410429	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2269G>T; p.D757Y; 18:79486463-79486463	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1111G>A; p.D371N; 18:79411425-79411425	liver	carcinoma	Substitution - Missense
c.1111G>A; p.D371N; 18:79411425-79411425	liver	carcinoma	Substitution - Missense
c.1111G>A; p.D371N; 18:79411425-79411425	liver	carcinoma	Substitution - Missense
c.1716C>T; p.I572I; 18:79451119-79451119	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1474A>C; p.T492P; 18:79448908-79448908	breast	carcinoma	Substitution - Missense
c.2759G>A; p.R920Q; 18:79527543-79527543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.746C>T; p.P249L; 18:79411060-79411060	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.529G>A; p.E177K; 18:79410843-79410843	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2510C>G; p.P837R; 18:79486704-79486704	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.557delC; p.Q188fs*95; 18:79410871-79410871	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2759G>A; p.R920Q; 18:79527543-79527543	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.625C>T; p.P209S; 18:79410939-79410939	skin	malignant_melanoma	Substitution - Missense
c.149C>G; p.S50C; 18:79410463-79410463	parathyroid	carcinoma	Substitution - Missense
c.423G>A; p.T141T; 18:79410737-79410737	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.706G>T; p.E236*; 18:79411020-79411020	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1657G>A; p.V553I; 18:79451060-79451060	breast	carcinoma	Substitution - Missense
c.1093A>T; p.R365W; 18:79411407-79411407	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1614G>A; p.T538T; 18:79451017-79451017	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1112A>G; p.D371G; 18:79411426-79411426	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2165C>T; p.A722V; 18:79486359-79486359	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.628C>A; p.R210S; 18:79410942-79410942	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.686C>T; p.P229L; 18:79411000-79411000	skin	malignant_melanoma	Substitution - Missense
c.1813G>T; p.G605C; 18:79451765-79451765	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1164C>T; p.P388P; 18:79411478-79411478	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.951C>T; p.G317G; 18:79411265-79411265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.537C>A; p.N179K; 18:79410851-79410851	liver	carcinoma	Substitution - Missense
c.537C>A; p.N179K; 18:79410851-79410851	liver	carcinoma	Substitution - Missense
c.1536C>G; p.N512K; 18:79448970-79448970	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1189C>T; p.P397S; 18:79433580-79433580	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.258C>A; p.G86G; 18:79410572-79410572	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.553G>A; p.A185T; 18:79410867-79410867	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.952G>A; p.V318I; 18:79411266-79411266	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.952G>A; p.V318I; 18:79411266-79411266	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1400C>T; p.T467M; 18:79448834-79448834	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1400C>T; p.T467M; 18:79448834-79448834	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2199C>T; p.A733A; 18:79486393-79486393	prostate	carcinoma	Substitution - coding silent
c.2085T>G; p.D695E; 18:79486279-79486279	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.706G>A; p.E236K; 18:79411020-79411020	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.107C>T; p.S36F; 18:79410421-79410421	skin	malignant_melanoma	Substitution - Missense
c.1392C>A; p.F464L; 18:79448826-79448826	pancreas	carcinoid-endocrine_tumour	Substitution - Missense
c.1298G>A; p.G433D; 18:79433689-79433689	breast	carcinoma	Substitution - Missense
c.1730G>A; p.R577H; 18:79451682-79451682	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1893G>A; p.A631A; 18:79461339-79461339	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1420C>T; p.R474C; 18:79448854-79448854	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1246C>T; p.R416W; 18:79433637-79433637	liver	carcinoma	Substitution - Missense
c.1925C>A; p.S642Y; 18:79467454-79467454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1925C>A; p.S642Y; 18:79467454-79467454	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1925C>A; p.S642Y; 18:79467454-79467454	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1681C>T; p.R561C; 18:79451084-79451084	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1191G>A; p.P397P; 18:79433582-79433582	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1817A>G; p.H606R; 18:79451769-79451769	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1054G>A; p.D352N; 18:79411368-79411368	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.987G>A; p.Q329Q; 18:79411301-79411301	pancreas	carcinoma	Substitution - coding silent
c.684G>A; p.S228S; 18:79410998-79410998	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.684G>A; p.S228S; 18:79410998-79410998	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.136_137CC>TT; p.P46F; 18:79410450-79410451	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2029C>T; p.R677C; 18:79467558-79467558	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.549G>A; p.P183P; 18:79410863-79410863	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.549G>A; p.P183P; 18:79410863-79410863	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1470C>T; p.S490S; 18:79448904-79448904	skin	malignant_melanoma	Substitution - coding silent
c.1342G>A; p.V448M; 18:79433733-79433733	large_intestine; colon	adenoma	Substitution - Missense
c.2493C>T; p.P831P; 18:79486687-79486687	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1629G>T; p.K543N; 18:79451032-79451032	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.163C>T; p.P55S; 18:79410477-79410477	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1740G>T; p.Q580H; 18:79451692-79451692	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2036C>T; p.T679I; 18:79467565-79467565	pancreas	carcinoma	Substitution - Missense
c.1649T>G; p.V550G; 18:79451052-79451052	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2036C>T; p.T679I; 18:79467565-79467565	pancreas	carcinoma	Substitution - Missense
c.2036C>T; p.T679I; 18:79467565-79467565	pancreas	carcinoma	Substitution - Missense
c.1649T>G; p.V550G; 18:79451052-79451052	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1649T>G; p.V550G; 18:79451052-79451052	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2036C>T; p.T679I; 18:79467565-79467565	pancreas	carcinoma	Substitution - Missense
c.2036C>T; p.T679I; 18:79467565-79467565	pancreas	carcinoma	Substitution - Missense
c.2577G>A; p.T859T; 18:79486771-79486771	pancreas	carcinoma	Substitution - coding silent
c.2177A>G; p.D726G; 18:79486371-79486371	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - Missense
c.1304delG; p.A437fs*2; 18:79433695-79433695	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2058A>G; p.P686P; 18:79486252-79486252	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1825C>T; p.L609L; 18:79451777-79451777	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2186C>G; p.S729C; 18:79486380-79486380	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2134C>T; p.L712F; 18:79486328-79486328	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1171C>T; p.P391S; 18:79411485-79411485	skin	malignant_melanoma	Substitution - Missense
c.1066G>A; p.E356K; 18:79411380-79411380	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.990G>A; p.P330P; 18:79411304-79411304	soft_tissue; striated_muscle	rhabdoid_tumour	Substitution - coding silent
c.2175C>T; p.P725P; 18:79486369-79486369	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.2175C>T; p.P725P; 18:79486369-79486369	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.214C>T; p.H72Y; 18:79410528-79410528	skin	malignant_melanoma	Substitution - Missense
c.2250C>T; p.G750G; 18:79486444-79486444	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1301G>T; p.S434I; 18:79433692-79433692	liver	carcinoma	Substitution - Missense
c.1301G>T; p.S434I; 18:79433692-79433692	liver	carcinoma	Substitution - Missense
c.1320G>A; p.A440A; 18:79433711-79433711	breast	carcinoma	Substitution - coding silent
c.1744C>T; p.L582L; 18:79451696-79451696	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1212G>A; p.W404*; 18:79433603-79433603	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.2598G>A; p.P866P; 18:79486792-79486792	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2359G>A; p.V787I; 18:79486553-79486553	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1212G>A; p.W404*; 18:79433603-79433603	large_intestine	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1565G>C; p.G522A; 18:79450968-79450968	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1428C>T; p.H476H; 18:79448862-79448862	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2046C>T; p.P682P; 18:79467575-79467575	central_nervous_system; brain	glioma	Substitution - coding silent
c.1269C>G; p.S423S; 18:79433660-79433660	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1993G>A; p.V665I; 18:79467522-79467522	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1993G>A; p.V665I; 18:79467522-79467522	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2213G>A; p.C738Y; 18:79486407-79486407	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; acute_lymphoblastic_leukaemia	Substitution - Missense
c.2053+8C>A; p.?; 18:79467590-79467590	liver	carcinoma	Unknown
c.2053+8C>A; p.?; 18:79467590-79467590	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.1921-1G>C; p.?; 18:79467449-79467449	lung; right_lower_lobe	carcinoma; adenocarcinoma	Unknown
c.353A>G; p.N118S; 18:79410667-79410667	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.566C>T; p.T189M; 18:79410880-79410880	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1920+1G>A; p.?; 18:79461367-79461367	skin	malignant_melanoma	Unknown
c.1061C>T; p.A354V; 18:79411375-79411375	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation