lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4437
Symbol	MSH3
Synonymous	DUP\|MRP1
Full name	mutS homolog 3
Gene description	DNA mismatch repair protein Msh3\|divergent upstream protein\|hMSH3\|mismatch repair protein 1
Cytoband	5q11-q12
Gene type	protein-coding
Synonymous	MIM:600887; HGNC:HGNC:7326; Ensembl:ENSG00000113318; HPRD:02931; Vega:OTTHUMG00000162540

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1919A>C; p.K640T; 5:80767982-80767982	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2353C>T; p.Q785*; 5:80778781-80778781	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Nonsense
c.2433_2434insT; p.L812fs*3; 5:80787589-80787590	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Insertion - Frameshift
c.2192C>T; p.P731L; 5:80768969-80768969	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2146G>A; p.E716K; 5:80768923-80768923	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2020G>C; p.E674Q; 5:80768083-80768083	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2287G>A; p.G763R; 5:80775754-80775754	skin	malignant_melanoma	Substitution - Missense
c.1114_1115delAA; p.K374fs*20; 5:80675096-80675097	large_intestine; rectum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2551A>C; p.K851Q; 5:80792767-80792767	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2550delA; p.N852fs*6; 5:80792766-80792766	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.320C>T; p.S107F; 5:80656520-80656520	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.3285C>G; p.L1095L; 5:80875760-80875760	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2318C>T; p.S773F; 5:80778746-80778746	skin	malignant_melanoma	Substitution - Missense
c.2263A>C; p.I755L; 5:80775730-80775730	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2058A>T; p.K686N; 5:80768835-80768835	liver	carcinoma	Substitution - Missense
c.3308C>T; p.T1103M; 5:80875783-80875783	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2058A>T; p.K686N; 5:80768835-80768835	liver	carcinoma	Substitution - Missense
c.279G>T; p.K93N; 5:80656479-80656479	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.3103+1G>T; p.?; 5:80864943-80864943	lung	carcinoma; adenocarcinoma	Unknown
c.2311T>C; p.F771L; 5:80778739-80778739	ovary	carcinoma	Substitution - Missense
c.1334G>T; p.R445L; 5:80725473-80725473	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2367G>T; p.Q789H; 5:80778795-80778795	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1813C>T; p.H605Y; 5:80761622-80761622	skin	malignant_melanoma	Substitution - Missense
c.1813C>T; p.H605Y; 5:80761622-80761622	skin	malignant_melanoma	Substitution - Missense
c.181-4T>G; p.?; 5:80654931-80654931	thyroid	other; neoplasm	Unknown
c.181-4T>G; p.?; 5:80654931-80654931	liver	carcinoma	Unknown
c.1209A>G; p.S403S; 5:80678989-80678989	skin	malignant_melanoma	Substitution - coding silent
c.2862C>T; p.I954I; 5:80854205-80854205	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1712T>C; p.V571A; 5:80744591-80744591	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2981C>T; p.S994F; 5:80864820-80864820	skin	malignant_melanoma	Substitution - Missense
c.3371C>T; p.T1124I; 5:80875846-80875846	skin	malignant_melanoma	Substitution - Missense
c.47C>A; p.S16*; 5:80654774-80654774	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.847G>C; p.V283L; 5:80672325-80672325	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1017C>T; p.I339I; 5:80674999-80674999	skin	malignant_melanoma	Substitution - coding silent
c.666G>A; p.P222P; 5:80670210-80670210	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.666G>A; p.P222P; 5:80670210-80670210	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.2960A>G; p.Y987C; 5:80854303-80854303	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2787G>T; p.R929S; 5:80854130-80854130	breast	carcinoma	Substitution - Missense
c.447G>T; p.E149D; 5:80665258-80665258	breast	carcinoma	Substitution - Missense
c.883-1G>A; p.?; 5:80672740-80672740	lung	carcinoma; adenocarcinoma	Unknown
c.1370G>A; p.S457N; 5:80725509-80725509	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.724G>T; p.E242*; 5:80670268-80670268	lung	carcinoma; non_small_cell_carcinoma	Substitution - Nonsense
c.151_159delGCTGCAGCG; p.A54_A56delAAA; 5:80654878-80654886	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.1542-1G>A; p.?; 5:80741463-80741463	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Unknown
c.1542-1G>A; p.?; 5:80741463-80741463	urinary_tract; bladder	carcinoma	Unknown
c.2358C>G; p.L786L; 5:80778786-80778786	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.632C>A; p.S211*; 5:80670176-80670176	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1234C>G; p.L412V; 5:80679014-80679014	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.643C>T; p.R215W; 5:80670187-80670187	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2204A>C; p.Y735S; 5:80768981-80768981	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1704G>A; p.K568K; 5:80744583-80744583	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1848C>T; p.L616L; 5:80761657-80761657	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2261G>T; p.C754F; 5:80775728-80775728	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.180+10C>G; p.?; 5:80654917-80654917	stomach	carcinoma; diffuse_adenocarcinoma	Unknown
c.180+10C>G; p.?; 5:80654917-80654917	stomach	carcinoma; diffuse_adenocarcinoma	Unknown
c.849T>C; p.V283V; 5:80672327-80672327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.3312G>A; p.M1104I; 5:80875787-80875787	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2964C>T; p.F988F; 5:80854307-80854307	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.2131C>T; p.Q711*; 5:80768908-80768908	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.2394G>A; p.W798*; 5:80778822-80778822	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1208C>G; p.S403*; 5:80678988-80678988	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1841G>A; p.R614K; 5:80761650-80761650	skin; trunk	malignant_melanoma	Substitution - Missense
c.2956G>C; p.E986Q; 5:80854299-80854299	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1826T>G; p.L609W; 5:80761635-80761635	skin	malignant_melanoma	Substitution - Missense
c.2332G>A; p.E778K; 5:80778760-80778760	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2800G>A; p.D934N; 5:80854143-80854143	ovary	carcinoma	Substitution - Missense
c.33C>T; p.L11L; 5:80654760-80654760	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.33C>T; p.L11L; 5:80654760-80654760	breast	carcinoma	Substitution - coding silent
c.772G>A; p.A258T; 5:80672250-80672250	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2447T>C; p.V816A; 5:80787603-80787603	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.2944T>C; p.Y982H; 5:80854287-80854287	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1614C>T; p.I538I; 5:80741536-80741536	skin	malignant_melanoma	Substitution - coding silent
c.2191C>T; p.P731S; 5:80768968-80768968	skin	malignant_melanoma	Substitution - Missense
c.2659G>A; p.G887R; 5:80813614-80813614	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2659G>A; p.G887R; 5:80813614-80813614	breast	carcinoma	Substitution - Missense
c.747C>A; p.F249L; 5:80670291-80670291	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2668A>G; p.M890V; 5:80813623-80813623	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.2931A>G; p.G977G; 5:80854274-80854274	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2537G>T; p.R846I; 5:80792753-80792753	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1114_1115insA; p.N376fs*19; 5:80675096-80675097	pancreas	carcinoma; acinar_carcinoma	Insertion - Frameshift
c.3255A>T; p.E1085D; 5:80873267-80873267	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1626+1G>C; p.?; 5:80741549-80741549	kidney	carcinoma; papillary_renal_cell_carcinoma	Unknown
c.3255A>T; p.E1085D; 5:80873267-80873267	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.14A>C; p.K5T; 5:80654741-80654741	liver	carcinoma	Substitution - Missense
c.14A>C; p.K5T; 5:80654741-80654741	liver	carcinoma	Substitution - Missense
c.150C>G; p.G50G; 5:80654877-80654877	thyroid	other; neoplasm	Substitution - coding silent
c.721G>A; p.V241M; 5:80670265-80670265	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.388G>T; p.E130*; 5:80665199-80665199	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2470T>C; p.C824R; 5:80787626-80787626	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1068C>T; p.T356T; 5:80675050-80675050	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1884G>T; p.E628D; 5:80767947-80767947	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1628C>T; p.T543I; 5:80744507-80744507	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.779A>G; p.E260G; 5:80672257-80672257	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.662C>T; p.T221M; 5:80670206-80670206	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2868A>T; p.K956N; 5:80854211-80854211	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.348G>A; p.L116L; 5:80665159-80665159	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.348G>A; p.L116L; 5:80665159-80665159	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.2572A>G; p.I858V; 5:80792788-80792788	breast	carcinoma	Substitution - Missense
c.1870-8A>G; p.?; 5:80767925-80767925	liver	carcinoma	Unknown
c.1870-8A>G; p.?; 5:80767925-80767925	liver	carcinoma	Unknown
c.876A>T; p.G292G; 5:80672354-80672354	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2066A>G; p.D689G; 5:80768843-80768843	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2677A>C; p.K893Q; 5:80813632-80813632	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1868A>C; p.K623T; 5:80761677-80761677	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.3321A>G; p.A1107A; 5:80875796-80875796	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1507G>T; p.E503*; 5:80728931-80728931	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2410A>T; p.K804*; 5:80787566-80787566	NS	NS	Substitution - Nonsense
c.874G>T; p.G292*; 5:80672352-80672352	lung	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.1786T>C; p.S596P; 5:80761595-80761595	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.1786T>C; p.S596P; 5:80761595-80761595	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2005C>T; p.L669F; 5:80768068-80768068	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1714A>C; p.T572P; 5:80744593-80744593	liver	carcinoma	Substitution - Missense
c.2420A>G; p.E807G; 5:80787576-80787576	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.217G>C; p.E73Q; 5:80656417-80656417	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2040C>A; p.L680L; 5:80768103-80768103	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.111C>T; p.T37T; 5:80654838-80654838	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.111C>T; p.T37T; 5:80654838-80654838	bone; fibula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.3379C>T; p.L1127F; 5:80875854-80875854	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.111C>T; p.T37T; 5:80654838-80654838	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2357T>A; p.L786H; 5:80778785-80778785	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.3026delA; p.N1011fs*40; 5:80864865-80864865	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2357T>A; p.L786H; 5:80778785-80778785	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2517-1G>A; p.?; 5:80792732-80792732	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.3170G>A; p.R1057K; 5:80873182-80873182	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1730A>C; p.K577T; 5:80744609-80744609	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1113_1114insA; p.N376fs*19; 5:80675095-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Insertion - Frameshift
c.719G>A; p.C240Y; 5:80670263-80670263	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2482C>T; p.L828L; 5:80787638-80787638	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1893G>C; p.L631F; 5:80767956-80767956	urinary_tract; bladder	carcinoma	Substitution - Missense
c.2588G>A; p.G863E; 5:80792804-80792804	breast	carcinoma	Substitution - Missense
c.2063G>T; p.G688V; 5:80768840-80768840	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	stomach	adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	skin	malignant_melanoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2989_2990delCT; p.L997fs*10; 5:80864828-80864829	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1150G>A; p.V384M; 5:80678930-80678930	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1114delA; p.K374fs*32; 5:80675096-80675096	stomach	adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1114delA; p.K374fs*32; 5:80675096-80675096	stomach	carcinoma; intestinal_adenocarcinoma	Deletion - Frameshift
c.1214T>C; p.L405P; 5:80678994-80678994	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1338C>T; p.V446V; 5:80725477-80725477	skin	malignant_melanoma	Substitution - coding silent
c.215C>A; p.T72K; 5:80656415-80656415	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.3093A>G; p.K1031K; 5:80864932-80864932	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1503C>G; p.L501L; 5:80728927-80728927	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1503C>G; p.L501L; 5:80728927-80728927	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.1736+7G>T; p.?; 5:80744622-80744622	liver	carcinoma	Unknown
c.1736+7G>T; p.?; 5:80744622-80744622	liver	carcinoma	Unknown
c.731G>A; p.G244E; 5:80670275-80670275	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.2644G>T; p.V882L; 5:80813599-80813599	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.180+7C>G; p.?; 5:80654914-80654914	stomach	carcinoma; diffuse_adenocarcinoma	Unknown
c.2268A>T; p.P756P; 5:80775735-80775735	breast	carcinoma	Substitution - coding silent
c.2316_2317delCT; p.P774fs*19; 5:80778744-80778745	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Deletion - Frameshift
c.251A>C; p.N84T; 5:80656451-80656451	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2145C>T; p.D715D; 5:80768922-80768922	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2020G>T; p.E674*; 5:80768083-80768083	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1501C>T; p.L501F; 5:80728925-80728925	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1093A>C; p.N365H; 5:80675075-80675075	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2409-6C>T; p.?; 5:80787559-80787559	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.180C>T; p.P60P; 5:80654907-80654907	thyroid	other; neoplasm	Substitution - coding silent
c.2244G>T; p.K748N; 5:80775711-80775711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2244G>T; p.K748N; 5:80775711-80775711	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2588G>T; p.G863V; 5:80792804-80792804	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.427C>T; p.Q143*; 5:80665238-80665238	liver	carcinoma	Substitution - Nonsense
c.1408G>T; p.D470Y; 5:80725547-80725547	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.427C>T; p.Q143*; 5:80665238-80665238	liver	carcinoma	Substitution - Nonsense
c.1408G>T; p.D470Y; 5:80725547-80725547	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.777A>G; p.R259R; 5:80672255-80672255	liver	carcinoma	Substitution - coding silent
c.777A>G; p.R259R; 5:80672255-80672255	liver	carcinoma	Substitution - coding silent
c.1204C>T; p.R402C; 5:80678984-80678984	skin	malignant_melanoma	Substitution - Missense
c.2919C>T; p.S973S; 5:80854262-80854262	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1950T>G; p.V650V; 5:80768013-80768013	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.3105C>T; p.G1035G; 5:80873117-80873117	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; Burkitt_lymphoma	Substitution - coding silent
c.329C>G; p.S110C; 5:80656529-80656529	breast	carcinoma	Substitution - Missense
c.3219T>G; p.I1073M; 5:80873231-80873231	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2576A>G; p.D859G; 5:80792792-80792792	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2160T>A; p.H720Q; 5:80768937-80768937	breast	carcinoma	Substitution - Missense
c.967G>A; p.A323T; 5:80672825-80672825	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.339G>T; p.K113N; 5:80665150-80665150	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1432C>G; p.Q478E; 5:80728856-80728856	urinary_tract; bladder	carcinoma	Substitution - Missense
c.989T>A; p.L330H; 5:80672847-80672847	kidney	other; neoplasm	Substitution - Missense
c.1436T>C; p.I479T; 5:80728860-80728860	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1436T>C; p.I479T; 5:80728860-80728860	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.897G>A; p.K299K; 5:80672755-80672755	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2332G>C; p.E778Q; 5:80778760-80778760	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1127A>T; p.N376I; 5:80675109-80675109	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2621A>T; p.D874V; 5:80792837-80792837	pancreas	carcinoma	Substitution - Missense
c.1916T>C; p.L639P; 5:80767979-80767979	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.181-9C>G; p.?; 5:80654926-80654926	lung	carcinoma; adenocarcinoma	Unknown
c.181-9C>G; p.?; 5:80654926-80654926	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Unknown
c.3106G>A; p.A1036T; 5:80873118-80873118	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.502G>A; p.A168T; 5:80665313-80665313	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.57G>A; p.A19A; 5:80654784-80654784	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1223G>A; p.R408Q; 5:80679003-80679003	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.3103+2T>C; p.?; 5:80864944-80864944	oesophagus	carcinoma; adenocarcinoma	Unknown
c.59G>A; p.R20K; 5:80654786-80654786	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation