lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4353
Symbol	MPO
Synonymous	-
Full name	myeloperoxidase
Gene description	-
Cytoband	17q23.1
Gene type	protein-coding
Synonymous	MIM:606989; HGNC:HGNC:7218; Ensembl:ENSG00000005381; HPRD:06102; Vega:OTTHUMG00000178922

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.1382A>G; p.D461G; 17:58273653-58273653	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1231G>A; p.E411K; 17:58275676-58275676	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.65delG; p.G22fs*6; 17:58280694-58280694	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2225G>A; p.R742K; 17:58270669-58270669	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2031-6A>C; p.?; 17:58270869-58270869	stomach	carcinoma; adenocarcinoma	Unknown
c.1053G>A; p.R351R; 17:58277978-58277978	skin	malignant_melanoma	Substitution - coding silent
c.1053G>A; p.R351R; 17:58277978-58277978	skin	malignant_melanoma	Substitution - coding silent
c.1175G>A; p.R392H; 17:58277856-58277856	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1937G>T; p.G646V; 17:58271748-58271748	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.157G>T; p.V53F; 17:58280457-58280457	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.1995C>T; p.I665I; 17:58271690-58271690	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.2017C>T; p.R673W; 17:58271668-58271668	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1543C>T; p.R515W; 17:58273492-58273492	skin	malignant_melanoma	Substitution - Missense
c.1466G>A; p.R489H; 17:58273569-58273569	pancreas	carcinoma	Substitution - Missense
c.1015G>A; p.A339T; 17:58278016-58278016	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.890C>T; p.P297L; 17:58278141-58278141	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1866G>A; p.R622R; 17:58271819-58271819	skin	malignant_melanoma	Substitution - coding silent
c.1772G>A; p.S591N; 17:58272768-58272768	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1262G>T; p.R421L; 17:58275645-58275645	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1730T>A; p.M577K; 17:58272810-58272810	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2114A>G; p.D705G; 17:58270780-58270780	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1339C>T; p.R447W; 17:58275568-58275568	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1531C>T; p.R511C; 17:58273504-58273504	skin	malignant_melanoma	Substitution - Missense
c.1470C>T; p.I490I; 17:58273565-58273565	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2232C>T; p.A744A; 17:58270662-58270662	ovary	other; neoplasm	Substitution - coding silent
c.886-1G>A; p.?; 17:58278146-58278146	breast	carcinoma	Unknown
c.1501G>A; p.G501S; 17:58273534-58273534	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.403C>T; p.R135*; 17:58279860-58279860	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.403C>T; p.R135*; 17:58279860-58279860	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1281C>A; p.A427A; 17:58275626-58275626	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.1281C>A; p.A427A; 17:58275626-58275626	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - coding silent
c.1347C>T; p.I449I; 17:58275560-58275560	skin	malignant_melanoma	Substitution - coding silent
c.1347C>T; p.I449I; 17:58275560-58275560	skin	malignant_melanoma	Substitution - coding silent
c.1347C>T; p.I449I; 17:58275560-58275560	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1536G>A; p.L512L; 17:58273499-58273499	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.706C>T; p.R236C; 17:58279187-58279187	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.243G>A; p.R81R; 17:58280371-58280371	skin	malignant_melanoma	Substitution - coding silent
c.1567C>T; p.P523S; 17:58273468-58273468	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1896G>A; p.E632E; 17:58271789-58271789	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.435G>A; p.T145T; 17:58279636-58279636	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2041G>C; p.E681Q; 17:58270853-58270853	skin	malignant_melanoma	Substitution - Missense
c.2041G>C; p.E681Q; 17:58270853-58270853	skin	malignant_melanoma	Substitution - Missense
c.100G>T; p.A34S; 17:58280659-58280659	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.404G>A; p.R135Q; 17:58279859-58279859	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1005C>T; p.S335S; 17:58278026-58278026	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1144C>A; p.L382M; 17:58277887-58277887	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1066A>G; p.M356V; 17:58277965-58277965	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.195C>T; p.S65S; 17:58280419-58280419	skin	malignant_melanoma	Substitution - coding silent
c.1411G>A; p.A471T; 17:58273624-58273624	skin	malignant_melanoma	Substitution - Missense
c.1157C>G; p.P386R; 17:58277874-58277874	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.2055G>A; p.V685V; 17:58270839-58270839	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.118C>G; p.L40V; 17:58280641-58280641	urinary_tract; bladder	carcinoma	Substitution - Missense
c.594G>A; p.W198*; 17:58279381-58279381	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.118C>G; p.L40V; 17:58280641-58280641	urinary_tract; bladder	carcinoma	Substitution - Missense
c.118C>G; p.L40V; 17:58280641-58280641	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1815C>A; p.F605L; 17:58271870-58271870	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.118C>G; p.L40V; 17:58280641-58280641	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.118C>G; p.L40V; 17:58280641-58280641	breast	carcinoma	Substitution - Missense
c.546C>G; p.N182K; 17:58279525-58279525	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1971G>A; p.V657V; 17:58271714-58271714	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1640T>C; p.L547P; 17:58272900-58272900	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1518A>G; p.Q506Q; 17:58273517-58273517	skin	malignant_melanoma	Substitution - coding silent
c.1520C>T; p.P507L; 17:58273515-58273515	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2056T>C; p.F686L; 17:58270838-58270838	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1618G>A; p.E540K; 17:58273417-58273417	skin	malignant_melanoma	Substitution - Missense
c.1939G>T; p.V647L; 17:58271746-58271746	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1149C>T; p.H383H; 17:58277882-58277882	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2030G>T; p.R677L; 17:58271655-58271655	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1639C>T; p.L547F; 17:58272901-58272901	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1594T>G; p.F532V; 17:58273441-58273441	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1768C>T; p.R590C; 17:58272772-58272772	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.633C>T; p.Y211Y; 17:58279342-58279342	pancreas	NS	Substitution - coding silent
c.951G>A; p.P317P; 17:58278080-58278080	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1786C>T; p.L596F; 17:58272754-58272754	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1808G>T; p.R603M; 17:58271877-58271877	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1008C>T; p.F336F; 17:58278023-58278023	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.475G>A; p.A159T; 17:58279596-58279596	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1008C>T; p.F336F; 17:58278023-58278023	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.1246C>A; p.H416N; 17:58275661-58275661	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.475G>A; p.A159T; 17:58279596-58279596	liver	carcinoma	Substitution - Missense
c.475G>A; p.A159T; 17:58279596-58279596	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1853G>A; p.G618D; 17:58271832-58271832	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.2179T>G; p.F727V; 17:58270715-58270715	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2085C>A; p.A695A; 17:58270809-58270809	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.2170C>T; p.P724S; 17:58270724-58270724	skin	malignant_melanoma	Substitution - Missense
c.1103G>A; p.R368H; 17:58277928-58277928	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.994G>A; p.A332T; 17:58278037-58278037	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1103G>A; p.R368H; 17:58277928-58277928	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1828C>T; p.Q610*; 17:58271857-58271857	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1283C>G; p.T428R; 17:58275624-58275624	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1283C>G; p.T428R; 17:58275624-58275624	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2226G>A; p.R742R; 17:58270668-58270668	skin; leg	malignant_melanoma	Substitution - coding silent
c.1817G>A; p.C606Y; 17:58271868-58271868	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2226G>A; p.R742R; 17:58270668-58270668	skin; leg	malignant_melanoma	Substitution - coding silent
c.2226G>A; p.R742R; 17:58270668-58270668	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1092C>T; p.A364A; 17:58277939-58277939	skin	malignant_melanoma	Substitution - coding silent
c.1019G>C; p.S340T; 17:58278012-58278012	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1340G>A; p.R447Q; 17:58275567-58275567	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1340G>A; p.R447Q; 17:58275567-58275567	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2067G>A; p.Q689Q; 17:58270827-58270827	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2067G>A; p.Q689Q; 17:58270827-58270827	upper_aerodigestive_tract; mouth	carcinoma	Substitution - coding silent
c.789C>G; p.L263L; 17:58279104-58279104	breast	carcinoma	Substitution - coding silent
c.1827G>A; p.P609P; 17:58271858-58271858	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1827G>A; p.P609P; 17:58271858-58271858	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.225G>T; p.K75N; 17:58280389-58280389	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1783G>A; p.G595S; 17:58272757-58272757	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1754C>A; p.A585D; 17:58272786-58272786	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2030G>A; p.R677Q; 17:58271655-58271655	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1636A>G; p.I546V; 17:58272904-58272904	breast	carcinoma	Substitution - Missense
c.1793G>A; p.G598E; 17:58271892-58271892	skin	malignant_melanoma	Substitution - Missense
c.442C>A; p.Q148K; 17:58279629-58279629	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.872G>A; p.C291Y; 17:58279021-58279021	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1043C>T; p.P348L; 17:58277988-58277988	skin	malignant_melanoma	Substitution - Missense
c.1772G>T; p.S591I; 17:58272768-58272768	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.888C>T; p.I296I; 17:58278143-58278143	skin	malignant_melanoma	Substitution - coding silent
c.315G>A; p.P105P; 17:58279948-58279948	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.315G>A; p.P105P; 17:58279948-58279948	bone	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.922G>A; p.D308N; 17:58278109-58278109	central_nervous_system; brain	glioma	Substitution - Missense
c.1837A>C; p.T613P; 17:58271848-58271848	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1174C>T; p.R392C; 17:58277857-58277857	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1174C>T; p.R392C; 17:58277857-58277857	biliary_tract; bile_duct	carcinoma; adenocarcinoma	Substitution - Missense
c.589C>T; p.R197C; 17:58279386-58279386	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2224A>G; p.R742G; 17:58270670-58270670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.392G>T; p.R131L; 17:58279871-58279871	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.2224A>G; p.R742G; 17:58270670-58270670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2224A>G; p.R742G; 17:58270670-58270670	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.879G>A; p.P293P; 17:58279014-58279014	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1921G>A; p.D641N; 17:58271764-58271764	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1387C>T; p.L463L; 17:58273648-58273648	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1921G>A; p.D641N; 17:58271764-58271764	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1117G>A; p.G373S; 17:58277914-58277914	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1117G>A; p.G373S; 17:58277914-58277914	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1236C>T; p.L412L; 17:58275671-58275671	breast	carcinoma	Substitution - coding silent
c.180G>A; p.S60S; 17:58280434-58280434	bone; tibia	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - coding silent
c.1744G>C; p.D582H; 17:58272796-58272796	urinary_tract; bladder	carcinoma	Substitution - Missense
c.752T>C; p.M251T; 17:58279141-58279141	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.470G>A; p.G157D; 17:58279601-58279601	stomach	adenocarcinoma	Substitution - Missense
c.1371C>T; p.I457I; 17:58273664-58273664	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.265C>T; p.R89C; 17:58279998-58279998	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.591C>T; p.R197R; 17:58279384-58279384	breast	carcinoma	Substitution - coding silent
c.1275G>A; p.R425R; 17:58275632-58275632	stomach	adenocarcinoma	Substitution - coding silent
c.1086G>T; p.L362L; 17:58277945-58277945	lung; left_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1956G>T; p.K652N; 17:58271729-58271729	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1618G>C; p.E540Q; 17:58273417-58273417	breast	carcinoma; HER-positive_carcinoma	Substitution - Missense
c.271G>A; p.G91S; 17:58279992-58279992	soft_tissue; striated_muscle	rhabdoid_tumour	Substitution - Missense
c.1880C>T; p.A627V; 17:58271805-58271805	pancreas	carcinoma	Substitution - Missense
c.165G>A; p.G55G; 17:58280449-58280449	skin	malignant_melanoma	Substitution - coding silent
c.168G>A; p.E56E; 17:58280446-58280446	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1379G>A; p.R460Q; 17:58273656-58273656	skin	malignant_melanoma	Substitution - Missense
c.1495C>T; p.R499C; 17:58273540-58273540	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.963delG; p.S322fs*112; 17:58278068-58278068	lung	carcinoma; adenocarcinoma	Deletion - Frameshift
c.391C>T; p.R131W; 17:58279872-58279872	skin	malignant_melanoma	Substitution - Missense
c.583T>A; p.F195I; 17:58279392-58279392	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1302C>A; p.N434K; 17:58275605-58275605	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.333G>T; p.T111T; 17:58279930-58279930	upper_aerodigestive_tract; larynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1599C>T; p.A533A; 17:58273436-58273436	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.18C>A; p.F6L; 17:58280741-58280741	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.18C>A; p.F6L; 17:58280741-58280741	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2100C>A; p.P700P; 17:58270794-58270794	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.18C>A; p.F6L; 17:58280741-58280741	pancreas	carcinoma	Substitution - Missense
c.1641C>T; p.L547L; 17:58272899-58272899	skin	malignant_melanoma	Substitution - coding silent
c.2174G>A; p.R725Q; 17:58270720-58270720	breast	carcinoma	Substitution - Missense
c.1899G>T; p.Q633H; 17:58271786-58271786	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.1769G>A; p.R590H; 17:58272771-58272771	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1197C>T; p.F399F; 17:58277834-58277834	pancreas	carcinoma	Substitution - coding silent
c.1769G>A; p.R590H; 17:58272771-58272771	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.345C>T; p.A115A; 17:58279918-58279918	oesophagus	carcinoma; adenocarcinoma	Substitution - coding silent
c.767G>A; p.G256D; 17:58279126-58279126	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.345C>T; p.A115A; 17:58279918-58279918	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1205-7C>T; p.?; 17:58275709-58275709	skin; head_neck	malignant_melanoma; superficial_spreading	Unknown
c.2225G>T; p.R742M; 17:58270669-58270669	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1860G>T; p.V620V; 17:58271825-58271825	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2127C>T; p.I709I; 17:58270767-58270767	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2018G>T; p.R673L; 17:58271667-58271667	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.936C>A; p.F312L; 17:58278095-58278095	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1061G>A; p.R354H; 17:58277970-58277970	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1561C>A; p.P521T; 17:58273474-58273474	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.1076A>T; p.Q359L; 17:58277955-58277955	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.2092T>A; p.S698T; 17:58270802-58270802	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.2013G>T; p.K671N; 17:58271672-58271672	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1645G>A; p.G549S; 17:58272895-58272895	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.833G>C; p.G278A; 17:58279060-58279060	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1840G>C; p.V614L; 17:58271845-58271845	breast	carcinoma	Substitution - Missense
c.909C>G; p.I303M; 17:58278122-58278122	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.909C>G; p.I303M; 17:58278122-58278122	urinary_tract; bladder	carcinoma	Substitution - Missense
c.909C>G; p.I303M; 17:58278122-58278122	urinary_tract; bladder	carcinoma	Substitution - Missense
c.332C>T; p.T111M; 17:58279931-58279931	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.135C>T; p.P45P; 17:58280624-58280624	central_nervous_system; brain	glioma	Substitution - coding silent
c.50C>A; p.P17H; 17:58280709-58280709	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1432A>T; p.T478S; 17:58273603-58273603	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1073A>G; p.N358S; 17:58277958-58277958	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1590C>A; p.V530V; 17:58273445-58273445	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1545G>A; p.R515R; 17:58273490-58273490	skin; head_neck	malignant_melanoma; superficial_spreading	Substitution - coding silent
c.192C>T; p.S64S; 17:58280422-58280422	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1966C>T; p.R656C; 17:58271719-58271719	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1530C>T; p.F510F; 17:58273505-58273505	skin	malignant_melanoma	Substitution - coding silent
c.1857G>A; p.T619T; 17:58271828-58271828	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1036G>A; p.E346K; 17:58277995-58277995	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1184G>A; p.R395H; 17:58277847-58277847	breast	carcinoma	Substitution - Missense
c.789C>T; p.L263L; 17:58279104-58279104	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1184G>A; p.R395H; 17:58277847-58277847	central_nervous_system; brain	glioma	Substitution - Missense
c.1967G>A; p.R656H; 17:58271718-58271718	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.1070C>T; p.S357F; 17:58277961-58277961	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.179C>T; p.S60L; 17:58280435-58280435	skin	malignant_melanoma	Substitution - Missense
c.1603T>A; p.W535R; 17:58273432-58273432	breast	carcinoma; basal_(triple-negative)_carcinoma	Substitution - Missense
c.1070C>T; p.S357F; 17:58277961-58277961	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1967G>A; p.R656H; 17:58271718-58271718	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation