Cancer metastasis database

Annotation category 5

Gene information

Gene ID 4350
Symbol

MPG

Synonymous

AAG|ADPG|APNG|CRA36.1|MDG|Mid1|PIG11|PIG16|anpg

Full name

N-methylpurine-DNA glycosylase

Gene description

3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p|3-alkyladenine DNA glycosylase|3-methyladenine DNA glycosidase|CRA36.1 (3-methyl-adenine DNA glycosylase)|DNA-3-methyladenine glycosylase|N-methylpurine-DNA glycosylase, MP

Cytoband

16p13.3

Gene type

protein-coding

Synonymous

MIM:156565; HGNC:HGNC:7211; Ensembl:ENSG00000103152; HPRD:06766; Vega:OTTHUMG00000047887

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.194C>T; p.P65L; 16:79579-79579

 ovaryother; neoplasmSubstitution - Missense

c.194C>T; p.P65L; 16:79579-79579

 ovaryother; neoplasmSubstitution - Missense

c.112G>A; p.A38T; 16:79497-79497

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.353G>A; p.R118Q; 16:83089-83089

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.353G>A; p.R118Q; 16:83089-83089

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.82G>A; p.A28T; 16:79467-79467

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.109G>A; p.A37T; 16:79494-79494

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.846C>T; p.S282S; 16:85726-85726

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.846C>T; p.S282S; 16:85726-85726

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.428delC; p.R145fs*7; 16:83164-83164

 large_intestine; caecumcarcinoma; adenocarcinomaDeletion - Frameshift

c.7_8insC; p.A5fs*23; 16:79299-79300

 salivary_glandcarcinoma; adenoid_cystic_carcinomaInsertion - Frameshift

c.583C>T; p.Q195*; 16:85463-85463

 breastcarcinomaSubstitution - Nonsense

c.614C>A; p.A205D; 16:85494-85494

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.841G>T; p.G281C; 16:85721-85721

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.298C>T; p.R100W; 16:79683-79683

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.298C>T; p.R100W; 16:79683-79683

 stomachcarcinoma; diffuse_adenocarcinomaSubstitution - Missense

c.102G>A; p.S34S; 16:79487-79487

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.267G>C; p.E89D; 16:79652-79652

 stomachcarcinoma; mixed_intestinal_and_diffuse_adenocarcinoma-unclassifiableSubstitution - Missense

c.49C>T; p.R17W; 16:79434-79434

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.472G>A; p.V158M; 16:83208-83208

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.589C>T; p.R197C; 16:85469-85469

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.359G>A; p.R120H; 16:83095-83095

 skinmalignant_melanomaSubstitution - Missense

c.782G>A; p.R261Q; 16:85662-85662

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.270C>T; p.F90F; 16:79655-79655

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.668A>C; p.Q223P; 16:85548-85548

 thyroidother; neoplasmSubstitution - Missense

c.434G>A; p.R145H; 16:83170-83170

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.434G>A; p.R145H; 16:83170-83170

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.281C>T; p.P94L; 16:79666-79666

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.523G>A; p.D175N; 16:85403-85403

 meningesmeningiomaSubstitution - Missense

c.681C>T; p.I227I; 16:85561-85561

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.154G>T; p.A52S; 16:79539-79539

 lungcarcinoma; non_small_cell_carcinomaSubstitution - Missense

c.191C>T; p.P64L; 16:79576-79576

 upper_aerodigestive_tract; mouthcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.816G>A; p.R272R; 16:85696-85696

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.275A>C; p.D92A; 16:79660-79660

 breastcarcinomaSubstitution - Missense

c.805G>A; p.E269K; 16:85685-85685

 skinmalignant_melanomaSubstitution - Missense

c.805G>A; p.E269K; 16:85685-85685

 skinmalignant_melanomaSubstitution - Missense

c.805G>A; p.E269K; 16:85685-85685

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.140G>C; p.S47T; 16:79525-79525

 breastcarcinomaSubstitution - Missense

c.627C>G; p.L209L; 16:85507-85507

 ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.631G>T; p.D211Y; 16:85511-85511

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.464delC; p.L156fs*13; 16:83200-83200

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - Frameshift

c.13G>A; p.A5T; 16:79305-79305

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.635G>A; p.R212H; 16:85515-85515

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.640C>T; p.L214F; 16:85520-85520

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.450C>T; p.F150F; 16:83186-83186

 breastcarcinomaSubstitution - coding silent

c.632A>G; p.D211G; 16:85512-85512

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.307C>T; p.L103L; 16:79692-79692

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.442G>A; p.G148S; 16:83178-83178

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.435C>A; p.R145R; 16:83171-83171

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.178C>T; p.R60C; 16:79563-79563

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.143C>T; p.S48L; 16:79528-79528

 skinmalignant_melanomaSubstitution - Missense