Cancer metastasis database

Annotation category 5

Gene information

Gene ID 4326
Symbol

MMP17

Synonymous

MT4-MMP

Full name

matrix metallopeptidase 17 (membrane-inserted)

Gene description

MMP-17|MT-MMP 4|MT4MMP|MTMMP4|matrix metalloproteinase 17 (membrane-inserted)|matrix metalloproteinase-17|membrane-type matrix metalloproteinase 4|membrane-type-4 matrix metalloproteinase

Cytoband

12q24.3

Gene type

protein-coding

Synonymous

MIM:602285; HGNC:HGNC:7163; Ensembl:ENSG00000198598; HPRD:03793; Vega:OTTHUMG00000168050

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.1510G>T; p.V504L; 12:131850972-131850972

 lung; middle_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.617_618insT; p.G207fs*22; 12:131840767-131840768

 breastcarcinomaInsertion - Frameshift

c.1092G>T; p.R364R; 12:131845337-131845337

 central_nervous_system; braingliomaSubstitution - coding silent

c.780C>T; p.S260S; 12:131841697-131841697

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1075C>T; p.R359W; 12:131845320-131845320

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1383G>T; p.T461T; 12:131849980-131849980

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1357C>T; p.L453L; 12:131849954-131849954

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1357C>T; p.L453L; 12:131849954-131849954

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1357C>T; p.L453L; 12:131849954-131849954

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.1317C>A; p.S439S; 12:131849914-131849914

 ovaryother; neoplasmSubstitution - coding silent

c.981C>T; p.P327P; 12:131845130-131845130

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.1712C>T; p.S571F; 12:131851174-131851174

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.1162G>A; p.V388M; 12:131845407-131845407

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1237G>A; p.D413N; 12:131849834-131849834

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.990C>T; p.D330D; 12:131845139-131845139

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.486C>T; p.L162L; 12:131840636-131840636

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.1440C>A; p.S480R; 12:131850037-131850037

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.1161C>T; p.S387S; 12:131845406-131845406

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1806G>A; p.Q602Q; 12:131851268-131851268

 pancreascarcinomaSubstitution - coding silent

c.373C>T; p.R125C; 12:131838692-131838692

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.R125C; 12:131838692-131838692

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.R125C; 12:131838692-131838692

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.373C>T; p.R125C; 12:131838692-131838692

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.1158C>T; p.D386D; 12:131845403-131845403

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.612C>T; p.D204D; 12:131840762-131840762

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.612C>T; p.D204D; 12:131840762-131840762

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.502A>G; p.K168E; 12:131840652-131840652

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.1397C>T; p.P466L; 12:131849994-131849994

 skinmalignant_melanomaSubstitution - Missense

c.77T>C; p.L26P; 12:131828571-131828571

 livercarcinomaSubstitution - Missense

c.77T>C; p.L26P; 12:131828571-131828571

 livercarcinomaSubstitution - Missense

c.657C>T; p.H219H; 12:131840807-131840807

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.544G>A; p.A182T; 12:131840694-131840694

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.544G>A; p.A182T; 12:131840694-131840694

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.544G>A; p.A182T; 12:131840694-131840694

 thyroidother; neoplasmSubstitution - Missense

c.544G>A; p.A182T; 12:131840694-131840694

 thyroidother; neoplasmSubstitution - Missense

c.1561C>A; p.R521R; 12:131851023-131851023

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.911C>T; p.S304F; 12:131844024-131844024

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.547G>A; p.G183S; 12:131840697-131840697

 breastcarcinomaSubstitution - Missense

c.594C>T; p.N198N; 12:131840744-131840744

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.1294G>A; p.G432S; 12:131849891-131849891

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.1260C>T; p.Y420Y; 12:131849857-131849857

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent