lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4311
Symbol	MME
Synonymous	CALLA\|CD10\|NEP\|SFE
Full name	membrane metallo-endopeptidase
Gene description	atriopeptidase\|common acute lymphocytic leukemia antigen\|enkephalinase\|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase)\|membrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, CD10)\|membrane metallo-endopeptidase
Cytoband	3q25.2
Gene type	protein-coding
Synonymous	MIM:120520; HGNC:HGNC:7154; Ensembl:ENSG00000196549; HPRD:00392; Vega:OTTHUMG00000158455

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.2247T>C; p.V749V; 3:155180453-155180453	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1164G>T; p.K388N; 3:155142306-155142306	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1712A>C; p.N571T; 3:155166953-155166953	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1440C>T; p.I480I; 3:155147167-155147167	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1893G>A; p.W631*; 3:155168604-155168604	urinary_tract; bladder	carcinoma	Substitution - Nonsense
c.1915-1G>A; p.?; 3:155168731-155168731	skin	malignant_melanoma	Unknown
c.1524C>T; p.F508F; 3:155148576-155148576	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1099C>A; p.L367I; 3:155142241-155142241	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.907A>G; p.M303V; 3:155140242-155140242	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2216C>T; p.S739L; 3:155180422-155180422	skin	malignant_melanoma	Substitution - Missense
c.1602-1G>T; p.?; 3:155160389-155160389	lung	carcinoma; adenocarcinoma	Unknown
c.573G>A; p.L191L; 3:155116905-155116905	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1184G>A; p.R395H; 3:155142326-155142326	prostate	carcinoma	Substitution - Missense
c.1184G>A; p.R395H; 3:155142326-155142326	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; NK-T_cell_lymphoma	Substitution - Missense
c.381T>A; p.T127T; 3:155116501-155116501	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1272G>A; p.G424G; 3:155143526-155143526	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1781G>T; p.G594V; 3:155168492-155168492	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.679C>T; p.P227S; 3:155118770-155118770	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1075C>A; p.L359I; 3:155142108-155142108	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.850G>T; p.A284S; 3:155138231-155138231	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.971T>A; p.L324*; 3:155142004-155142004	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Nonsense
c.885T>G; p.D295E; 3:155140220-155140220	liver	carcinoma	Substitution - Missense
c.1516G>T; p.E506*; 3:155148568-155148568	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Nonsense
c.645T>C; p.H215H; 3:155116977-155116977	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - coding silent
c.2243G>A; p.R748Q; 3:155180449-155180449	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.645T>C; p.H215H; 3:155116977-155116977	soft_tissue; striated_muscle	rhabdomyosarcoma	Substitution - coding silent
c.645T>C; p.H215H; 3:155116977-155116977	soft_tissue; striated_muscle	rhabdomyosarcoma; embryonal	Substitution - coding silent
c.1388C>A; p.A463D; 3:155144429-155144429	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1178C>A; p.A393D; 3:155142320-155142320	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.303C>G; p.S101R; 3:155115100-155115100	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1686C>T; p.P562P; 3:155166927-155166927	skin	malignant_melanoma	Substitution - coding silent
c.909G>A; p.M303I; 3:155140244-155140244	prostate	adenoma	Substitution - Missense
c.612T>C; p.F204F; 3:155116944-155116944	skin	malignant_melanoma	Substitution - coding silent
c.2061C>T; p.F687F; 3:155172197-155172197	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.348C>T; p.V116V; 3:155115145-155115145	skin	malignant_melanoma	Substitution - coding silent
c.2024delT; p.P676fs*5; 3:155172160-155172160	bone; femur	chondrosarcoma	Deletion - Frameshift
c.1605G>A; p.W535*; 3:155160393-155160393	skin	malignant_melanoma	Substitution - Nonsense
c.1095-1G>A; p.?; 3:155142236-155142236	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Unknown
c.286G>A; p.V96I; 3:155115083-155115083	haematopoietic_and_lymphoid_tissue; central_nervous_system	lymphoid_neoplasm; primary_central_nervous_system_lymphoma	Substitution - Missense
c.653A>C; p.H218P; 3:155116985-155116985	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1466A>G; p.N489S; 3:155147193-155147193	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.667C>T; p.R223*; 3:155118758-155118758	skin	malignant_melanoma	Substitution - Nonsense
c.1318G>A; p.V440I; 3:155144359-155144359	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2044C>T; p.H682Y; 3:155172180-155172180	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.87_88CA>AG; p.S30G; 3:155084254-155084255	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.362T>C; p.V121A; 3:155116482-155116482	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2110G>T; p.V704F; 3:155172569-155172569	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.362T>C; p.V121A; 3:155116482-155116482	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.1124T>G; p.F375C; 3:155142266-155142266	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.736G>A; p.V246M; 3:155138117-155138117	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1590G>T; p.V530V; 3:155148642-155148642	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.2230G>C; p.E744Q; 3:155180436-155180436	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.160+1G>A; p.?; 3:155084328-155084328	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.1700C>T; p.A567V; 3:155166941-155166941	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.844G>A; p.E282K; 3:155138225-155138225	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1684delC; p.F564fs*10; 3:155166925-155166925	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1809C>T; p.L603L; 3:155168520-155168520	skin	malignant_melanoma	Substitution - coding silent
c.831_832GG>AA; p.M277_E278>IK; 3:155138212-155138213	skin; head_neck	carcinoma; squamous_cell_carcinoma	Complex - compound substitution
c.197-2A>T; p.?; 3:155114992-155114992	kidney	other; neoplasm	Unknown
c.93C>A; p.L31L; 3:155084260-155084260	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1228C>T; p.R410C; 3:155143482-155143482	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1228C>T; p.R410C; 3:155143482-155143482	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1362T>C; p.T454T; 3:155144403-155144403	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1096G>T; p.D366Y; 3:155142238-155142238	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.963C>G; p.F321L; 3:155141996-155141996	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.167T>A; p.I56N; 3:155085065-155085065	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.385G>C; p.D129H; 3:155116505-155116505	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.294C>T; p.P98P; 3:155115091-155115091	oesophagus	carcinoma	Substitution - coding silent
c.1857C>T; p.S619S; 3:155168568-155168568	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.878G>A; p.R293Q; 3:155140213-155140213	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.878G>A; p.R293Q; 3:155140213-155140213	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.433A>C; p.N145H; 3:155116553-155116553	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.691T>G; p.Y231D; 3:155118782-155118782	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.761G>C; p.R254T; 3:155138142-155138142	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.152delC; p.Y52fs*12; 3:155084319-155084319	lung	carcinoma; squamous_cell_carcinoma	Deletion - Frameshift
c.1390G>C; p.E464Q; 3:155144431-155144431	breast	carcinoma	Substitution - Missense
c.1447C>G; p.P483A; 3:155147174-155147174	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.668G>A; p.R223Q; 3:155118759-155118759	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1165G>A; p.E389K; 3:155142307-155142307	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.997A>T; p.T333S; 3:155142030-155142030	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.56A>T; p.K19M; 3:155084223-155084223	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.589A>G; p.K197E; 3:155116921-155116921	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2118C>T; p.S706S; 3:155172577-155172577	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.589A>G; p.K197E; 3:155116921-155116921	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.2016A>C; p.E672D; 3:155172152-155172152	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1804G>C; p.D602H; 3:155168515-155168515	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1320C>A; p.V440V; 3:155144361-155144361	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.358+1G>A; p.?; 3:155115156-155115156	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.912A>G; p.T304T; 3:155140247-155140247	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.2144G>C; p.G715A; 3:155172603-155172603	autonomic_ganglia	neuroblastoma	Substitution - Missense
c.958C>G; p.P320A; 3:155141991-155141991	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1607T>C; p.I536T; 3:155160395-155160395	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1751A>G; p.H584R; 3:155166992-155166992	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.654+1G>A; p.?; 3:155116987-155116987	large_intestine; colon	carcinoma; adenocarcinoma	Unknown
c.426T>G; p.S142S; 3:155116546-155116546	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1154G>A; p.R385Q; 3:155142296-155142296	skin	malignant_melanoma	Substitution - Missense
c.1154G>A; p.R385Q; 3:155142296-155142296	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.109C>T; p.L37F; 3:155084276-155084276	skin	malignant_melanoma	Substitution - Missense
c.985G>A; p.E329K; 3:155142018-155142018	skin	malignant_melanoma	Substitution - Missense
c.985G>A; p.E329K; 3:155142018-155142018	skin	malignant_melanoma	Substitution - Missense
c.309T>C; p.R103R; 3:155115106-155115106	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1545G>A; p.L515L; 3:155148597-155148597	skin	malignant_melanoma	Substitution - coding silent
c.1309A>G; p.K437E; 3:155143563-155143563	skin	malignant_melanoma	Substitution - Missense
c.1357C>G; p.Q453E; 3:155144398-155144398	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1147C>A; p.L383I; 3:155142289-155142289	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.769C>T; p.R257C; 3:155138150-155138150	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.769C>T; p.R257C; 3:155138150-155138150	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1753G>A; p.E585K; 3:155166994-155166994	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.1753G>A; p.E585K; 3:155166994-155166994	prostate	carcinoma	Substitution - Missense
c.1838G>A; p.S613N; 3:155168549-155168549	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1363T>A; p.L455I; 3:155144404-155144404	pancreas	carcinoma	Substitution - Missense
c.334G>C; p.D112H; 3:155115131-155115131	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.934T>C; p.F312L; 3:155140269-155140269	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.264C>A; p.C88*; 3:155115061-155115061	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.739G>T; p.D247Y; 3:155138120-155138120	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1781-3T>G; p.?; 3:155168489-155168489	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Unknown
c.739G>T; p.D247Y; 3:155138120-155138120	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.739G>T; p.D247Y; 3:155138120-155138120	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1558A>C; p.S520R; 3:155148610-155148610	skin	malignant_melanoma	Substitution - Missense
c.412G>A; p.A138T; 3:155116532-155116532	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.952G>T; p.G318W; 3:155140287-155140287	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.851C>G; p.A284G; 3:155138232-155138232	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.196+2T>A; p.?; 3:155085096-155085096	ovary	other; neoplasm	Unknown
c.1317G>T; p.V439V; 3:155143571-155143571	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.402G>C; p.Q134H; 3:155116522-155116522	urinary_tract; bladder	carcinoma	Substitution - Missense
c.402G>C; p.Q134H; 3:155116522-155116522	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.308G>A; p.R103H; 3:155115105-155115105	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.308G>A; p.R103H; 3:155115105-155115105	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.308G>A; p.R103H; 3:155115105-155115105	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1131G>T; p.M377I; 3:155142273-155142273	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1726G>T; p.G576W; 3:155166967-155166967	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1944C>T; p.N648N; 3:155168761-155168761	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1944C>T; p.N648N; 3:155168761-155168761	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1944C>T; p.N648N; 3:155168761-155168761	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.157G>A; p.D53N; 3:155084324-155084324	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.91C>T; p.L31F; 3:155084258-155084258	skin	malignant_melanoma	Substitution - Missense
c.1146C>A; p.S382R; 3:155142288-155142288	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1889C>T; p.S630F; 3:155168600-155168600	skin	malignant_melanoma	Substitution - Missense
c.1771G>A; p.D591N; 3:155167012-155167012	pancreas	carcinoma	Substitution - Missense
c.1771G>A; p.D591N; 3:155167012-155167012	pancreas	carcinoma; ductal_carcinoma	Substitution - Missense
c.814G>A; p.E272K; 3:155138195-155138195	skin	malignant_melanoma	Substitution - Missense
c.814G>A; p.E272K; 3:155138195-155138195	skin	malignant_melanoma	Substitution - Missense
c.1423G>A; p.A475T; 3:155147150-155147150	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1771G>A; p.D591N; 3:155167012-155167012	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1538A>G; p.Q513R; 3:155148590-155148590	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.288C>G; p.V96V; 3:155115085-155115085	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.844G>T; p.E282*; 3:155138225-155138225	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.838G>A; p.E280K; 3:155138219-155138219	skin	malignant_melanoma	Substitution - Missense
c.831G>A; p.M277I; 3:155138212-155138212	skin	malignant_melanoma	Substitution - Missense
c.414A>G; p.A138A; 3:155116534-155116534	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.838G>A; p.E280K; 3:155138219-155138219	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2020T>G; p.L674V; 3:155172156-155172156	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1802G>A; p.G601E; 3:155168513-155168513	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.361G>A; p.V121I; 3:155116481-155116481	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.34G>A; p.D12N; 3:155084201-155084201	skin	malignant_melanoma	Substitution - Missense
c.506T>A; p.V169E; 3:155116730-155116730	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.930T>C; p.N310N; 3:155140265-155140265	breast	carcinoma	Substitution - coding silent
c.318C>A; p.N106K; 3:155115115-155115115	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.862G>A; p.A288T; 3:155140197-155140197	skin	malignant_melanoma	Substitution - Missense
c.1076T>G; p.L359R; 3:155142109-155142109	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.921G>T; p.Q307H; 3:155140256-155140256	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.824A>C; p.K275T; 3:155138205-155138205	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.697G>A; p.E233K; 3:155118788-155118788	skin	malignant_melanoma	Substitution - Missense
c.2014G>C; p.E672Q; 3:155172150-155172150	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1070C>T; p.P357L; 3:155142103-155142103	skin	malignant_melanoma	Substitution - Missense
c.2010C>T; p.G670G; 3:155172146-155172146	breast	carcinoma	Substitution - coding silent
c.623A>G; p.D208G; 3:155116955-155116955	liver	carcinoma	Substitution - Missense
c.623A>G; p.D208G; 3:155116955-155116955	liver	carcinoma	Substitution - Missense
c.972G>T; p.L324F; 3:155142005-155142005	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1914C>T; p.H638H; 3:155168625-155168625	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.268G>T; p.G90C; 3:155115065-155115065	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1780+2T>A; p.?; 3:155167023-155167023	lung	carcinoma; squamous_cell_carcinoma	Unknown
c.67C>T; p.R23*; 3:155084234-155084234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.67C>T; p.R23*; 3:155084234-155084234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.2102A>T; p.E701V; 3:155172561-155172561	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.67C>T; p.R23*; 3:155084234-155084234	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1771G>T; p.D591Y; 3:155167012-155167012	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.112C>A; p.L38I; 3:155084279-155084279	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.597C>G; p.V199V; 3:155116929-155116929	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.68G>A; p.R23Q; 3:155084235-155084235	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1305G>A; p.E435E; 3:155143559-155143559	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.884A>T; p.D295V; 3:155140219-155140219	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1761C>T; p.T587T; 3:155167002-155167002	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.776A>T; p.E259V; 3:155138157-155138157	skin	malignant_melanoma	Substitution - Missense
c.1090G>A; p.A364T; 3:155142123-155142123	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.553G>A; p.E185K; 3:155116885-155116885	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1390G>A; p.E464K; 3:155144431-155144431	liver	carcinoma	Substitution - Missense
c.1390G>A; p.E464K; 3:155144431-155144431	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1125C>T; p.F375F; 3:155142267-155142267	skin	malignant_melanoma	Substitution - coding silent
c.224C>T; p.A75V; 3:155115021-155115021	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1287A>G; p.E429E; 3:155143541-155143541	prostate	carcinoma; adenocarcinoma	Substitution - coding silent
c.1765G>T; p.G589C; 3:155167006-155167006	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.2235G>A; p.K745K; 3:155180441-155180441	skin	malignant_melanoma	Substitution - coding silent
c.1000G>T; p.V334L; 3:155142033-155142033	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.5G>A; p.G2D; 3:155084172-155084172	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.720+9delA; p.?; 3:155118820-155118820	liver	carcinoma; hepatocellular_carcinoma	Unknown
c.427T>C; p.C143R; 3:155116547-155116547	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.427T>C; p.C143R; 3:155116547-155116547	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1729G>A; p.G577S; 3:155166970-155166970	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1856C>G; p.S619C; 3:155168567-155168567	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.1343G>T; p.R448L; 3:155144384-155144384	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1671C>A; p.A557A; 3:155166912-155166912	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2172G>A; p.Q724Q; 3:155180378-155180378	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - coding silent
c.610T>C; p.F204L; 3:155116942-155116942	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1683G>T; p.Q561H; 3:155166924-155166924	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.829A>G; p.M277V; 3:155138210-155138210	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.308G>T; p.R103L; 3:155115105-155115105	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1905T>G; p.G635G; 3:155168616-155168616	breast	carcinoma	Substitution - coding silent
c.138C>T; p.I46I; 3:155084305-155084305	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.934T>G; p.F312V; 3:155140269-155140269	liver	carcinoma	Substitution - Missense
c.934T>G; p.F312V; 3:155140269-155140269	liver	carcinoma	Substitution - Missense
c.934T>G; p.F312V; 3:155140269-155140269	liver	carcinoma	Substitution - Missense
c.2025T>A; p.L675L; 3:155172161-155172161	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1914+1G>A; p.?; 3:155168626-155168626	endometrium	carcinoma; endometrioid_carcinoma	Unknown
c.1816T>G; p.W606G; 3:155168527-155168527	central_nervous_system; brain	primitive_neuroectodermal_tumour-medulloblastoma	Substitution - Missense
c.139G>A; p.A47T; 3:155084306-155084306	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1320C>T; p.V440V; 3:155144361-155144361	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1312C>T; p.H438Y; 3:155143566-155143566	liver	carcinoma	Substitution - Missense
c.908T>C; p.M303T; 3:155140243-155140243	liver	carcinoma	Substitution - Missense
c.1320C>T; p.V440V; 3:155144361-155144361	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1312C>T; p.H438Y; 3:155143566-155143566	liver	carcinoma	Substitution - Missense
c.1312C>T; p.H438Y; 3:155143566-155143566	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.76C>T; p.P26S; 3:155084243-155084243	skin	malignant_melanoma	Substitution - Missense
c.1320C>T; p.V440V; 3:155144361-155144361	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1320C>T; p.V440V; 3:155144361-155144361	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.908T>C; p.M303T; 3:155140243-155140243	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.281G>A; p.R94H; 3:155115078-155115078	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1661-7C>T; p.?; 3:155166895-155166895	skin; leg	malignant_melanoma	Unknown
c.1661-7C>T; p.?; 3:155166895-155166895	skin; leg	malignant_melanoma	Unknown
c.1276C>T; p.L426F; 3:155143530-155143530	skin	malignant_melanoma	Substitution - Missense
c.1541A>C; p.N514T; 3:155148593-155148593	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1276C>T; p.L426F; 3:155143530-155143530	skin	malignant_melanoma	Substitution - Missense
c.6C>A; p.G2G; 3:155084173-155084173	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.280C>T; p.R94C; 3:155115077-155115077	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1447C>T; p.P483S; 3:155147174-155147174	skin	malignant_melanoma	Substitution - Missense
c.354G>A; p.L118L; 3:155115151-155115151	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.280C>T; p.R94C; 3:155115077-155115077	oesophagus	carcinoma	Substitution - Missense
c.280C>T; p.R94C; 3:155115077-155115077	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1623A>G; p.V541V; 3:155160411-155160411	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.819G>C; p.M273I; 3:155138200-155138200	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1999A>T; p.K667*; 3:155172135-155172135	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.514G>A; p.E172K; 3:155116738-155116738	skin	malignant_melanoma	Substitution - Missense
c.346G>T; p.V116F; 3:155115143-155115143	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.346G>T; p.V116F; 3:155115143-155115143	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.346G>T; p.V116F; 3:155115143-155115143	large_intestine; colon	carcinoma	Substitution - Missense
c.346G>T; p.V116F; 3:155115143-155115143	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1921G>A; p.G641R; 3:155168738-155168738	skin	malignant_melanoma	Substitution - Missense
c.1113G>A; p.M371I; 3:155142255-155142255	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.312C>T; p.Y104Y; 3:155115109-155115109	pancreas	carcinoma	Substitution - coding silent
c.312C>T; p.Y104Y; 3:155115109-155115109	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1541A>T; p.N514I; 3:155148593-155148593	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.182A>T; p.D61V; 3:155085080-155085080	liver	carcinoma	Substitution - Missense
c.2211G>A; p.K737K; 3:155180417-155180417	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.723T>A; p.A241A; 3:155138104-155138104	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.219G>A; p.M73I; 3:155115016-155115016	skin	malignant_melanoma	Substitution - Missense
c.1781-1G>A; p.?; 3:155168491-155168491	liver	carcinoma	Unknown
c.488A>G; p.D163G; 3:155116712-155116712	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1781-1G>A; p.?; 3:155168491-155168491	liver	carcinoma	Unknown
c.958C>T; p.P320S; 3:155141991-155141991	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.156C>T; p.Y52Y; 3:155084323-155084323	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.521G>A; p.W174*; 3:155116745-155116745	skin	malignant_melanoma	Substitution - Nonsense
c.578C>A; p.S193Y; 3:155116910-155116910	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1890C>T; p.S630S; 3:155168601-155168601	skin	malignant_melanoma	Substitution - coding silent
c.1640C>A; p.S547Y; 3:155160428-155160428	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.82G>A; p.E28K; 3:155084249-155084249	skin	malignant_melanoma	Substitution - Missense
c.1250G>A; p.G417E; 3:155143504-155143504	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.870T>C; p.P290P; 3:155140205-155140205	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.376A>G; p.K126E; 3:155116496-155116496	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.971T>C; p.L324S; 3:155142004-155142004	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.856G>A; p.A286T; 3:155140191-155140191	skin	malignant_melanoma	Substitution - Missense
c.856G>A; p.A286T; 3:155140191-155140191	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation