| Gene ID | 4192 |
| Symbol | MDK |
| Synonymous | ARAP|MK|NEGF2 |
| Full name | midkine (neurite growth-promoting factor 2) |
| Gene description | amphiregulin-associated protein|midgestation and kidney protein|midkine|neurite outgrowth-promoting factor 2|retinoic acid inducible factor |
| Cytoband | 11p11.2 |
| Gene type | protein-coding |
| Synonymous | MIM:162096; HGNC:HGNC:6972; Ensembl:ENSG00000110492; HPRD:01200; Vega:OTTHUMG00000150315 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.29C>T; p.T10I; 11:46382086-46382086 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - Missense |
c.66_67insA; p.K25fs*3; 11:46382123-46382124 |
large_intestine | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.420G>A; p.K140K; 11:46383482-46383482 |
skin | malignant_melanoma | Substitution - coding silent |
c.324G>A; p.K108K; 11:46382666-46382666 |
lung | carcinoma; adenocarcinoma | Substitution - coding silent |
c.42G>A; p.L14L; 11:46382099-46382099 |
large_intestine; colon | carcinoma; adenocarcinoma | Substitution - coding silent |
c.42G>A; p.L14L; 11:46382099-46382099 |
thyroid | other; neoplasm | Substitution - coding silent |
c.245C>T; p.A82V; 11:46382587-46382587 |
central_nervous_system; brain | glioma; astrocytoma_Grade_IV | Substitution - Missense |
c.298A>C; p.T100P; 11:46382640-46382640 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.256T>C; p.Y86H; 11:46382598-46382598 |
large_intestine | carcinoma; adenocarcinoma | Substitution - Missense |
c.411G>T; p.K137N; 11:46383473-46383473 |
endometrium | carcinoma; endometrioid_carcinoma | Substitution - Missense |
c.343C>T; p.Q115*; 11:46382685-46382685 |
lung | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.128G>A; p.G43E; 11:46382345-46382345 |
skin | malignant_melanoma | Substitution - Missense |