Cancer metastasis database

Annotation category 5

Gene information

Gene ID 4171
Symbol

MCM2

Synonymous

BM28|CCNL1|CDCL1|D3S3194|MITOTIN|cdc19

Full name

minichromosome maintenance complex component 2

Gene description

DNA replication licensing factor MCM2|MCM2 minichromosome maintenance deficient 2, mitotin|cell devision cycle-like 1|cyclin-like 1|minichromosome maintenance deficient 2 (mitotin)|minichromosome maintenance protein 2 homolog|nuclear protein BM28

Cytoband

3q21

Gene type

protein-coding

Synonymous

MIM:116945; HGNC:HGNC:6944; Ensembl:ENSG00000073111; HPRD:00303; Vega:OTTHUMG00000159637

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.2368G>A; p.D790N; 3:127620800-127620800

ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.805G>A; p.A269T; 3:127606249-127606249

skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.2473C>T; p.R825W; 3:127621097-127621097

skinmalignant_melanomaSubstitution - Missense

c.2473C>T; p.R825W; 3:127621097-127621097

skinmalignant_melanomaSubstitution - Missense

c.789C>A; p.A263A; 3:127606233-127606233

ovarycarcinoma; serous_carcinomaSubstitution - coding silent

c.1999G>A; p.V667M; 3:127618067-127618067

stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.499A>G; p.M167V; 3:127604982-127604982

ovarycarcinoma; serous_carcinomaSubstitution - Missense