lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	4109
Symbol	MAGEA10
Synonymous	CT1.10\|MAGE10
Full name	melanoma antigen family A10
Gene description	MAGE-10 antigen\|cancer/testis antigen 1.10\|cancer/testis antigen family 1, member 10\|melanoma antigen family A, 10\|melanoma-associated antigen 10
Cytoband	Xq28
Gene type	protein-coding
Synonymous	MIM:300343; HGNC:HGNC:6797; Ensembl:ENSG00000124260; HPRD:02280; Vega:OTTHUMG00000024180

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.579A>T; p.E193D; 23:152135042-152135042	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.462G>A; p.P154P; 23:152135159-152135159	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.20G>A; p.R7H; 23:152135601-152135601	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.20G>A; p.R7H; 23:152135601-152135601	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.664C>G; p.P222A; 23:152134957-152134957	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1037C>T; p.A346V; 23:152134584-152134584	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.606C>T; p.V202V; 23:152135015-152135015	skin	malignant_melanoma	Substitution - coding silent
c.198A>T; p.L66L; 23:152135423-152135423	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.235G>T; p.E79*; 23:152135386-152135386	oesophagus	carcinoma; adenocarcinoma	Substitution - Nonsense
c.248C>T; p.P83L; 23:152135373-152135373	skin	malignant_melanoma	Substitution - Missense
c.998C>T; p.A333V; 23:152134623-152134623	skin	malignant_melanoma	Substitution - Missense
c.862G>A; p.G288S; 23:152134759-152134759	urinary_tract; bladder	carcinoma	Substitution - Missense
c.825G>T; p.W275C; 23:152134796-152134796	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.947C>G; p.A316G; 23:152134674-152134674	kidney	other; neoplasm	Substitution - Missense
c.330C>A; p.S110R; 23:152135291-152135291	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.174C>T; p.S58S; 23:152135447-152135447	skin	malignant_melanoma	Substitution - coding silent
c.673G>T; p.G225C; 23:152134948-152134948	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.281C>T; p.P94L; 23:152135340-152135340	skin	malignant_melanoma	Substitution - Missense
c.580G>T; p.V194L; 23:152135041-152135041	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.778G>A; p.E260K; 23:152134843-152134843	skin	malignant_melanoma	Substitution - Missense
c.740G>T; p.W247L; 23:152134881-152134881	skin	malignant_melanoma	Substitution - Missense
c.497delG; p.R166fs*26; 23:152135124-152135124	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.497delG; p.R166fs*26; 23:152135124-152135124	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.577G>A; p.E193K; 23:152135044-152135044	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.798G>T; p.E266D; 23:152134823-152134823	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.497delG; p.R166fs*26; 23:152135124-152135124	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.249T>G; p.P83P; 23:152135372-152135372	skin	malignant_melanoma	Substitution - coding silent
c.756G>A; p.M252I; 23:152134865-152134865	skin	malignant_melanoma	Substitution - Missense
c.756G>A; p.M252I; 23:152134865-152134865	skin	malignant_melanoma	Substitution - Missense
c.583delG; p.D195fs*21; 23:152135038-152135038	breast	carcinoma	Deletion - Frameshift
c.1096T>C; p.S366P; 23:152134525-152134525	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.232G>A; p.D78N; 23:152135389-152135389	skin	malignant_melanoma	Substitution - Missense
c.229G>A; p.D77N; 23:152135392-152135392	skin	malignant_melanoma	Substitution - Missense
c.229G>A; p.D77N; 23:152135392-152135392	skin	malignant_melanoma	Substitution - Missense
c.212C>A; p.P71Q; 23:152135409-152135409	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.50A>G; p.Q17R; 23:152135571-152135571	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1018A>T; p.R340*; 23:152134603-152134603	stomach	carcinoma; adenocarcinoma	Substitution - Nonsense
c.310C>A; p.Q104K; 23:152135311-152135311	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.750G>T; p.L250L; 23:152134871-152134871	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.254A>T; p.Q85L; 23:152135367-152135367	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1102C>A; p.P368T; 23:152134519-152134519	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.7C>A; p.R3R; 23:152135614-152135614	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.855G>T; p.Q285H; 23:152134766-152134766	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.706A>T; p.I236L; 23:152134915-152134915	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.877C>T; p.R293W; 23:152134744-152134744	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.247C>T; p.P83S; 23:152135374-152135374	skin	malignant_melanoma	Substitution - Missense
c.351A>G; p.P117P; 23:152135270-152135270	autonomic_ganglia	neuroblastoma	Substitution - coding silent
c.68A>G; p.Q23R; 23:152135553-152135553	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.219G>T; p.E73D; 23:152135402-152135402	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.913G>A; p.E305K; 23:152134708-152134708	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.913G>A; p.E305K; 23:152134708-152134708	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.355A>C; p.T119P; 23:152135266-152135266	breast	carcinoma	Substitution - Missense
c.119C>T; p.S40L; 23:152135502-152135502	skin	malignant_melanoma	Substitution - Missense
c.832G>A; p.E278K; 23:152134789-152134789	skin	malignant_melanoma	Substitution - Missense
c.832G>A; p.E278K; 23:152134789-152134789	skin	malignant_melanoma	Substitution - Missense
c.832G>A; p.E278K; 23:152134789-152134789	skin	malignant_melanoma	Substitution - Missense
c.923A>C; p.K308T; 23:152134698-152134698	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.774G>A; p.G258G; 23:152134847-152134847	skin	malignant_melanoma	Substitution - coding silent
c.47T>G; p.L16R; 23:152135574-152135574	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.501T>A; p.N167K; 23:152135120-152135120	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.219G>A; p.E73E; 23:152135402-152135402	skin	malignant_melanoma	Substitution - coding silent
c.1105G>T; p.E369*; 23:152134516-152134516	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.123C>A; p.S41S; 23:152135498-152135498	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.486G>A; p.E162E; 23:152135135-152135135	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1002G>C; p.L334F; 23:152134619-152134619	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.210C>T; p.T70T; 23:152135411-152135411	skin	malignant_melanoma	Substitution - coding silent
c.1072A>T; p.S358C; 23:152134549-152134549	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.338A>G; p.K113R; 23:152135283-152135283	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.921G>A; p.R307R; 23:152134700-152134700	skin	malignant_melanoma	Substitution - coding silent
c.921G>A; p.R307R; 23:152134700-152134700	skin	malignant_melanoma	Substitution - coding silent
c.921G>A; p.R307R; 23:152134700-152134700	skin	malignant_melanoma	Substitution - coding silent
c.819A>C; p.Q273H; 23:152134802-152134802	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.819A>C; p.Q273H; 23:152134802-152134802	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.157_158CC>TT; p.P53F; 23:152135463-152135464	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.406G>A; p.E136K; 23:152135215-152135215	skin	malignant_melanoma	Substitution - Missense
c.157C>T; p.P53S; 23:152135464-152135464	skin	malignant_melanoma	Substitution - Missense
c.460C>A; p.P154T; 23:152135161-152135161	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.946G>T; p.A316S; 23:152134675-152134675	lung	carcinoma; small_cell_carcinoma	Substitution - Missense
c.157C>T; p.P53S; 23:152135464-152135464	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.42A>C; p.E14D; 23:152135579-152135579	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1076C>A; p.S359Y; 23:152134545-152134545	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.94C>T; p.L32L; 23:152135527-152135527	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.713G>A; p.G238D; 23:152134908-152134908	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.691C>T; p.L231L; 23:152134930-152134930	skin	malignant_melanoma	Substitution - coding silent
c.643C>T; p.L215L; 23:152134978-152134978	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.17A>C; p.K6T; 23:152135604-152135604	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; diffuse_large_B_cell_lymphoma	Substitution - Missense
c.569A>C; p.D190A; 23:152135052-152135052	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.250C>T; p.P84S; 23:152135371-152135371	skin	malignant_melanoma	Substitution - Missense
c.44A>G; p.D15G; 23:152135577-152135577	ovary	other; neoplasm	Substitution - Missense
c.26G>C; p.R9P; 23:152135595-152135595	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.301C>T; p.P101S; 23:152135320-152135320	skin	malignant_melanoma	Substitution - Missense
c.971G>T; p.R324I; 23:152134650-152134650	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.877C>A; p.R293R; 23:152134744-152134744	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.948C>G; p.A316A; 23:152134673-152134673	pancreas	carcinoma	Substitution - coding silent
c.1102C>T; p.P368S; 23:152134519-152134519	upper_aerodigestive_tract; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.746C>A; p.A249E; 23:152134875-152134875	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.373G>C; p.D125H; 23:152135248-152135248	prostate	carcinoma	Substitution - Missense
c.973T>G; p.S325A; 23:152134648-152134648	skin; mucosal	malignant_melanoma	Substitution - Missense
c.783C>G; p.H261Q; 23:152134838-152134838	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.783C>G; p.H261Q; 23:152134838-152134838	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.77A>G; p.E26G; 23:152135544-152135544	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.296C>T; p.S99F; 23:152135325-152135325	skin	malignant_melanoma	Substitution - Missense
c.46C>A; p.L16I; 23:152135575-152135575	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.780G>T; p.E260D; 23:152134841-152134841	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.372A>G; p.P124P; 23:152135249-152135249	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.648T>G; p.S216R; 23:152134973-152134973	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.116C>T; p.S39L; 23:152135505-152135505	skin	malignant_melanoma	Substitution - Missense
c.22C>T; p.Q8*; 23:152135599-152135599	skin	malignant_melanoma	Substitution - Nonsense
c.860C>A; p.P287H; 23:152134761-152134761	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.48T>C; p.L16L; 23:152135573-152135573	skin	malignant_melanoma	Substitution - coding silent
c.959G>A; p.G320E; 23:152134662-152134662	skin	malignant_melanoma	Substitution - Missense
c.1072A>G; p.S358G; 23:152134549-152134549	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.140C>T; p.S47F; 23:152135481-152135481	skin	malignant_melanoma	Substitution - Missense
c.645G>A; p.L215L; 23:152134976-152134976	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.936G>A; p.L312L; 23:152134685-152134685	skin	malignant_melanoma	Substitution - coding silent
c.936G>A; p.L312L; 23:152134685-152134685	skin	malignant_melanoma	Substitution - coding silent
c.624C>T; p.G208G; 23:152134997-152134997	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.76G>A; p.E26K; 23:152135545-152135545	stomach	adenocarcinoma	Substitution - Missense
c.206G>A; p.S69N; 23:152135415-152135415	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.438C>G; p.L146L; 23:152135183-152135183	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.280C>A; p.P94T; 23:152135341-152135341	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.816C>T; p.T272T; 23:152134805-152134805	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.343G>T; p.E115*; 23:152135278-152135278	breast	carcinoma	Substitution - Nonsense
c.355A>G; p.T119A; 23:152135266-152135266	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.783C>A; p.H261Q; 23:152134838-152134838	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.540C>T; p.S180S; 23:152135081-152135081	prostate	carcinoma	Substitution - coding silent
c.975C>A; p.S325S; 23:152134646-152134646	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1040C>A; p.T347N; 23:152134581-152134581	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.586C>T; p.P196S; 23:152135035-152135035	skin	malignant_melanoma	Substitution - Missense
c.586C>T; p.P196S; 23:152135035-152135035	skin	malignant_melanoma	Substitution - Missense
c.231T>C; p.D77D; 23:152135390-152135390	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.586C>T; p.P196S; 23:152135035-152135035	skin	malignant_melanoma	Substitution - Missense
c.171T>C; p.S57S; 23:152135450-152135450	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.862G>C; p.G288R; 23:152134759-152134759	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.448C>T; p.Q150*; 23:152135173-152135173	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.878G>A; p.R293Q; 23:152134743-152134743	urinary_tract; bladder	carcinoma	Substitution - Missense
c.878G>A; p.R293Q; 23:152134743-152134743	urinary_tract; bladder	carcinoma; transitional_cell_carcinoma	Substitution - Missense
c.168C>T; p.S56S; 23:152135453-152135453	skin	malignant_melanoma	Substitution - coding silent
c.25C>T; p.R9C; 23:152135596-152135596	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.168C>T; p.S56S; 23:152135453-152135453	skin	malignant_melanoma	Substitution - coding silent
c.1027G>A; p.D343N; 23:152134594-152134594	breast	carcinoma	Substitution - Missense
c.159C>T; p.P53P; 23:152135462-152135462	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1004A>G; p.K335R; 23:152134617-152134617	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.98C>T; p.A33V; 23:152135523-152135523	skin	malignant_melanoma	Substitution - Missense
c.871C>T; p.P291S; 23:152134750-152134750	skin	malignant_melanoma	Substitution - Missense
c.871C>T; p.P291S; 23:152134750-152134750	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.209C>G; p.T70S; 23:152135412-152135412	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.165C>T; p.S55S; 23:152135456-152135456	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation