| Gene ID | 4082 |
| Symbol | MARCKS |
| Synonymous | 80K-L|MACS|PKCSL|PRKCSL |
| Full name | myristoylated alanine-rich protein kinase C substrate |
| Gene description | myristoylated alanine-rich C-kinase substrate|myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)|phosphomyristin|protein kinase C substrate, 80 kDa protein, light chain |
| Cytoband | 6q22.2 |
| Gene type | protein-coding |
| Synonymous | MIM:177061; HGNC:HGNC:6759; Ensembl:ENSG00000277443; HPRD:07519; Vega:OTTHUMG00000188327 |
Mutation (CDS; AA; Chr) | Site | Histology | Mutation Type |
|---|---|---|---|
c.453_454insA; p.K156fs*28; 6:113860033-113860034 |
large_intestine | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.453_454insA; p.K156fs*28; 6:113860033-113860034 |
large_intestine | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.86C>T; p.S29F; 6:113857831-113857831 |
skin | malignant_melanoma | Substitution - Missense |
c.499A>T; p.S167C; 6:113860079-113860079 |
lung | carcinoma; squamous_cell_carcinoma | Substitution - Missense |
c.93G>A; p.A31A; 6:113857838-113857838 |
oesophagus | carcinoma; adenocarcinoma | Substitution - coding silent |
c.582C>T; p.D194D; 6:113860162-113860162 |
stomach | carcinoma; adenocarcinoma | Substitution - coding silent |
c.974delC; p.P327fs*>6; 6:113860554-113860554 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.553G>A; p.E185K; 6:113860133-113860133 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.913G>A; p.A305T; 6:113860493-113860493 |
lung; right_upper_lobe | carcinoma; adenocarcinoma | Substitution - Missense |
c.923C>T; p.S308L; 6:113860503-113860503 |
lung | carcinoma; adenocarcinoma | Substitution - Missense |
c.202G>A; p.D68N; 6:113859782-113859782 |
ovary | other; neoplasm | Substitution - Missense |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
pancreas | pancreatic_intraepithelial_neoplasia_(PanIN) | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
liver | carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.454delA; p.K155fs*12; 6:113860034-113860034 |
upper_aerodigestive_tract; head_neck | carcinoma; squamous_cell_carcinoma | Deletion - Frameshift |
c.994G>C; p.E332Q; 6:113860574-113860574 |
urinary_tract; bladder | carcinoma | Substitution - Missense |
c.811G>T; p.E271*; 6:113860391-113860391 |
lung | carcinoma; adenocarcinoma | Substitution - Nonsense |
c.492C>T; p.F164F; 6:113860072-113860072 |
urinary_tract; bladder | carcinoma; transitional_cell_carcinoma | Substitution - coding silent |
c.492C>T; p.F164F; 6:113860072-113860072 |
urinary_tract; bladder | carcinoma | Substitution - coding silent |
c.872C>T; p.P291L; 6:113860452-113860452 |
stomach | carcinoma; adenocarcinoma | Substitution - Missense |
c.453_454insAA; p.K156fs*12; 6:113860033-113860034 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.54G>C; p.R18S; 6:113857799-113857799 |
kidney | carcinoma; clear_cell_renal_cell_carcinoma | Substitution - Missense |
c.973_974insC; p.A328fs*>6; 6:113860553-113860554 |
large_intestine; caecum | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.973_974insC; p.A328fs*>6; 6:113860553-113860554 |
large_intestine; colon | carcinoma; adenocarcinoma | Insertion - Frameshift |
c.454_455delAA; p.K155fs*28; 6:113860034-113860035 |
large_intestine; colon | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.454_455delAA; p.K155fs*28; 6:113860034-113860035 |
large_intestine | carcinoma; adenocarcinoma | Deletion - Frameshift |
c.941C>T; p.S314L; 6:113860521-113860521 |
breast | carcinoma | Substitution - Missense |