Cancer metastasis database

Annotation category 5

Gene information

Gene ID 397
Symbol

ARHGDIB

Synonymous

D4|GDIA2|GDID4|LYGDI|Ly-GDI|RAP1GN1|RhoGDI2

Full name

Rho GDP dissociation inhibitor (GDI) beta

Gene description

Rho GDI 2|rho GDP-dissociation inhibitor 2|rho-GDI beta

Cytoband

12p12.3

Gene type

protein-coding

Synonymous

MIM:602843; HGNC:HGNC:679; Ensembl:ENSG00000111348; HPRD:04162; Vega:OTTHUMG00000168742

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.504G>T; p.A168A; 12:14942624-14942624

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.343G>A; p.V115M; 12:14944839-14944839

 skinmalignant_melanomaSubstitution - Missense

c.416C>A; p.A139E; 12:14942712-14942712

 autonomic_ganglianeuroblastomaSubstitution - Missense

c.540C>T; p.D180D; 12:14942588-14942588

 central_nervous_system; braingliomaSubstitution - coding silent

c.540C>T; p.D180D; 12:14942588-14942588

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.92C>T; p.S31F; 12:14950621-14950621

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.323G>T; p.R108I; 12:14947892-14947892

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.136A>C; p.I46L; 12:14950577-14950577

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.185C>T; p.P62L; 12:14949882-14949882

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.512C>G; p.T171R; 12:14942616-14942616

 breastcarcinoma; basal_(triple-negative)_carcinomaSubstitution - Missense

c.514T>C; p.Y172H; 12:14942614-14942614

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.113T>C; p.M38T; 12:14950600-14950600

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.430G>T; p.G144C; 12:14942698-14942698

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.152C>T; p.T51M; 12:14950561-14950561

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.239C>T; p.P80L; 12:14949828-14949828

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.581C>T; p.S194L; 12:14942547-14942547

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.581C>T; p.S194L; 12:14942547-14942547

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.501G>T; p.L167L; 12:14942627-14942627

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.147G>T; p.K49N; 12:14950566-14950566

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.147G>T; p.K49N; 12:14950566-14950566

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.216C>A; p.L72L; 12:14949851-14949851

 livercarcinomaSubstitution - coding silent

c.216C>A; p.L72L; 12:14949851-14949851

 livercarcinomaSubstitution - coding silent

c.500T>C; p.L167P; 12:14942628-14942628

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.342+2T>G; p.?; 12:14947871-14947871

 livercarcinomaUnknown

c.593A>G; p.E198G; 12:14942535-14942535

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.153G>A; p.T51T; 12:14950560-14950560

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.582G>A; p.S194S; 12:14942546-14942546

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.355A>T; p.I119F; 12:14944827-14944827

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.256G>T; p.D86Y; 12:14949811-14949811

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; hairy_cell_leukaemiaSubstitution - Missense

c.23C>G; p.P8R; 12:14950690-14950690

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.515A>G; p.Y172C; 12:14942613-14942613

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.145A>G; p.K49E; 12:14950568-14950568

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.492G>T; p.K164N; 12:14942636-14942636

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.18A>G; p.P6P; 12:14950695-14950695

 skinmalignant_melanomaSubstitution - coding silent

c.201C>T; p.V67V; 12:14949866-14949866

 skinmalignant_melanomaSubstitution - coding silent

c.29T>G; p.V10G; 12:14950684-14950684

 livercarcinomaSubstitution - Missense

c.29T>G; p.V10G; 12:14950684-14950684

 livercarcinomaSubstitution - Missense

c.541G>A; p.D181N; 12:14942587-14942587

 skinmalignant_melanomaSubstitution - Missense

c.485C>A; p.A162D; 12:14942643-14942643

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.444T>C; p.P148P; 12:14942684-14942684

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.463T>C; p.F155L; 12:14942665-14942665

 livercarcinomaSubstitution - Missense

c.453G>A; p.E151E; 12:14942675-14942675

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.464T>C; p.F155S; 12:14942664-14942664

 oesophagus; lower_thirdcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.333T>G; p.I111M; 12:14947882-14947882

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.43G>A; p.D15N; 12:14950670-14950670

 central_nervous_system; braingliomaSubstitution - Missense

c.462G>T; p.E154D; 12:14942666-14942666

 breastcarcinomaSubstitution - Missense

c.544G>A; p.D182N; 12:14942584-14942584

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.561C>T; p.L187L; 12:14942567-14942567

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.130A>T; p.S44C; 12:14950583-14950583

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.274G>A; p.E92K; 12:14947941-14947941

 skin; mucosalmalignant_melanomaSubstitution - Missense

c.109G>A; p.E37K; 12:14950604-14950604

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.506G>A; p.R169Q; 12:14942622-14942622

 skinmalignant_melanomaSubstitution - Missense

c.506G>A; p.R169Q; 12:14942622-14942622

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.330A>G; p.K110K; 12:14947885-14947885

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.184C>T; p.P62S; 12:14949883-14949883

 skinmalignant_melanomaSubstitution - Missense

c.564C>T; p.S188S; 12:14942564-14942564

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.445C>A; p.R149R; 12:14942683-14942683

 livercarcinomaSubstitution - coding silent

c.445C>A; p.R149R; 12:14942683-14942683

 livercarcinomaSubstitution - coding silent

c.504G>C; p.A168A; 12:14942624-14942624

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - coding silent

c.372A>T; p.K124N; 12:14944810-14944810

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.597G>A; p.W199*; 12:14942531-14942531

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense