lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3960
Symbol	LGALS4
Synonymous	GAL4\|L36LBP
Full name	lectin, galactoside-binding, soluble, 4
Gene description	L-36 lactose-binding protein\|antigen NY-CO-27\|gal-4\|galectin 4\|galectin-4\|lactose-binding lectin 4
Cytoband	19q13.2
Gene type	protein-coding
Synonymous	MIM:602518; HGNC:HGNC:6565; Ensembl:ENSG00000171747; HPRD:03949; Vega:OTTHUMG00000182608

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.592C>T; p.L198L; 19:38802383-38802383	skin	malignant_melanoma	Substitution - coding silent
c.905C>T; p.S302L; 19:38801831-38801831	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.905C>T; p.S302L; 19:38801831-38801831	urinary_tract; bladder	carcinoma	Substitution - Missense
c.905C>T; p.S302L; 19:38801831-38801831	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.590G>A; p.R197K; 19:38802385-38802385	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.219G>T; p.K73N; 19:38808864-38808864	breast	carcinoma	Substitution - Missense
c.69C>G; p.I23M; 19:38812496-38812496	pancreas	carcinoma	Substitution - Missense
c.121G>A; p.E41K; 19:38812444-38812444	skin	malignant_melanoma	Substitution - Missense
c.69C>G; p.I23M; 19:38812496-38812496	pancreas	carcinoma	Substitution - Missense
c.197C>T; p.P66L; 19:38808886-38808886	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.474+2T>A; p.?; 19:38806459-38806459	large_intestine; caecum	carcinoma; adenocarcinoma	Unknown
c.724G>A; p.G242S; 19:38802093-38802093	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.462C>T; p.P154P; 19:38806473-38806473	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.777G>A; p.E259E; 19:38802040-38802040	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.785A>C; p.K262T; 19:38802032-38802032	skin	malignant_melanoma	Substitution - Missense
c.369G>A; p.E123E; 19:38806566-38806566	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.568C>T; p.P190S; 19:38803524-38803524	skin	malignant_melanoma	Substitution - Missense
c.501T>G; p.P167P; 19:38803869-38803869	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - coding silent
c.199C>T; p.R67W; 19:38808884-38808884	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.439A>C; p.I147L; 19:38806496-38806496	liver	carcinoma	Substitution - Missense
c.835C>G; p.R279G; 19:38801901-38801901	urinary_tract; bladder	carcinoma	Substitution - Missense
c.439A>C; p.I147L; 19:38806496-38806496	liver	carcinoma	Substitution - Missense
c.920T>G; p.V307G; 19:38801816-38801816	skin; upper_leg	malignant_melanoma	Substitution - Missense
c.811G>A; p.G271R; 19:38802006-38802006	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.409C>T; p.Q137*; 19:38806526-38806526	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.297C>T; p.A99A; 19:38808786-38808786	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.843C>T; p.G281G; 19:38801893-38801893	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.648C>T; p.P216P; 19:38802327-38802327	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.669C>A; p.I223I; 19:38802148-38802148	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.564C>G; p.F188L; 19:38803528-38803528	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.892G>T; p.A298S; 19:38801844-38801844	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.633G>A; p.K211K; 19:38802342-38802342	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.585C>T; p.F195F; 19:38802390-38802390	skin	malignant_melanoma	Substitution - coding silent
c.80T>C; p.L27P; 19:38812485-38812485	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.462_463CC>TT; p.L155F; 19:38806472-38806473	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.115G>A; p.A39T; 19:38812450-38812450	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.657G>C; p.K219N; 19:38802318-38802318	urinary_tract; bladder	carcinoma	Substitution - Missense
c.363C>A; p.F121L; 19:38806572-38806572	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.141C>T; p.F47F; 19:38808942-38808942	central_nervous_system; brain	glioma	Substitution - coding silent
c.922G>T; p.D308Y; 19:38801814-38801814	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.750C>T; p.S250S; 19:38802067-38802067	breast	carcinoma	Substitution - coding silent
c.542C>T; p.T181I; 19:38803550-38803550	skin	malignant_melanoma	Substitution - Missense
c.969C>T; p.I323I; 19:38801767-38801767	upper_aerodigestive_tract; pharynx	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.706C>T; p.H236Y; 19:38802111-38802111	ovary	other; neoplasm	Substitution - Missense
c.211T>C; p.W71R; 19:38808872-38808872	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.610G>A; p.A204T; 19:38802365-38802365	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.880C>G; p.L294V; 19:38801856-38801856	oesophagus; middle_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.81C>G; p.L27L; 19:38812484-38812484	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.244G>A; p.G82R; 19:38808839-38808839	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.244G>A; p.G82R; 19:38808839-38808839	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.898C>T; p.R300C; 19:38801838-38801838	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.345_347delGGT; p.V116delV; 19:38806588-38806590	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - In frame
c.656A>G; p.K219R; 19:38802319-38802319	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.691G>T; p.G231W; 19:38802126-38802126	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.246G>A; p.G82G; 19:38808837-38808837	skin	malignant_melanoma	Substitution - coding silent
c.819C>A; p.F273L; 19:38801998-38801998	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.864C>T; p.Y288Y; 19:38801872-38801872	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.556C>A; p.P186T; 19:38803536-38803536	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.703C>A; p.L235M; 19:38802114-38802114	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.719G>A; p.R240H; 19:38802098-38802098	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.719G>A; p.R240H; 19:38802098-38802098	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.719G>A; p.R240H; 19:38802098-38802098	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.477A>G; p.G159G; 19:38803893-38803893	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.578C>G; p.P193R; 19:38802397-38802397	oesophagus; upper_third	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.180C>T; p.V60V; 19:38808903-38808903	skin	malignant_melanoma	Substitution - coding silent
c.729C>T; p.N243N; 19:38802088-38802088	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.836G>A; p.R279H; 19:38801900-38801900	breast	carcinoma	Substitution - Missense
c.75C>T; p.G25G; 19:38812490-38812490	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.466C>T; p.R156W; 19:38806469-38806469	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.367G>T; p.E123*; 19:38806568-38806568	lung	carcinoma; adenocarcinoma	Substitution - Nonsense
c.461C>T; p.P154L; 19:38806474-38806474	skin	malignant_melanoma	Substitution - Missense
c.366T>A; p.Y122*; 19:38806569-38806569	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Nonsense
c.76G>A; p.G26R; 19:38812489-38812489	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.451G>A; p.G151R; 19:38806484-38806484	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.451G>A; p.G151R; 19:38806484-38806484	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.166_167CC>TT; p.P56L; 19:38808916-38808917	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.835C>T; p.R279C; 19:38801901-38801901	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.71C>A; p.P24Q; 19:38812494-38812494	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.605T>G; p.L202R; 19:38802370-38802370	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.245G>A; p.G82E; 19:38808838-38808838	skin	malignant_melanoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation