Cancer metastasis database

Annotation category 5

Gene information

Gene ID 396
Symbol

ARHGDIA

Synonymous

GDIA1|HEL-S-47e|NPHS8|RHOGDI|RHOGDI-1

Full name

Rho GDP dissociation inhibitor (GDI) alpha

Gene description

GDP-dissociation inhibitor, aplysia RAS-related 1|epididymis secretory sperm binding protein Li 47e|rho GDP-dissociation inhibitor 1

Cytoband

17q25.3

Gene type

protein-coding

Synonymous

MIM:601925; HGNC:HGNC:678; Ensembl:ENSG00000141522; HPRD:03565; Vega:OTTHUMG00000178352

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.495_496AC>TT; p.P166S; 17:81868995-81868996

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.505A>T; p.M169L; 17:81868986-81868986

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.412A>G; p.K138E; 17:81869176-81869176

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.118G>C; p.E40Q; 17:81869813-81869813

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.371C>T; p.S124F; 17:81869217-81869217

 skinmalignant_melanomaSubstitution - Missense

c.381G>A; p.K127K; 17:81869207-81869207

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.407G>A; p.G136D; 17:81869181-81869181

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.207C>T; p.N69N; 17:81869609-81869609

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.39G>A; p.Q13Q; 17:81869892-81869892

 skinmalignant_melanomaSubstitution - coding silent

c.253C>T; p.P85S; 17:81869563-81869563

 skinmalignant_melanomaSubstitution - Missense

c.600G>T; p.K200N; 17:81868891-81868891

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.477G>C; p.L159L; 17:81869014-81869014

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.406G>T; p.G136C; 17:81869182-81869182

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.199G>A; p.V67I; 17:81869617-81869617

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.337A>C; p.K113Q; 17:81869344-81869344

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.352-4G>A; p.?; 17:81869240-81869240

 prostatecarcinomaUnknown

c.587T>G; p.L196R; 17:81868904-81868904

 central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.514C>T; p.R172W; 17:81868977-81868977

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.21_22delAG; p.A8fs*14; 17:81869909-81869910

 oesophaguscarcinoma; adenocarcinomaDeletion - Frameshift

c.133G>A; p.D45N; 17:81869798-81869798

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.527delG; p.S176fs*>29; 17:81868964-81868964

 kidneycarcinoma; clear_cell_renal_cell_carcinomaDeletion - Frameshift

c.598A>G; p.K200E; 17:81868893-81868893

 livercarcinomaSubstitution - Missense

c.598A>G; p.K200E; 17:81868893-81868893

 livercarcinomaSubstitution - Missense

c.545C>G; p.T182R; 17:81868946-81868946

 livercarcinomaSubstitution - Missense

c.545C>G; p.T182R; 17:81868946-81868946

 livercarcinomaSubstitution - Missense

c.89delC; p.P30fs*43; 17:81869842-81869842

 livercarcinoma; hepatocellular_carcinomaDeletion - Frameshift

c.340A>G; p.I114V; 17:81869341-81869341

 livercarcinomaSubstitution - Missense

c.340A>G; p.I114V; 17:81869341-81869341

 livercarcinomaSubstitution - Missense

c.265G>A; p.D89N; 17:81869551-81869551

 breastcarcinomaSubstitution - Missense

c.409G>A; p.V137I; 17:81869179-81869179

 thyroidother; neoplasmSubstitution - Missense

c.357C>T; p.N119N; 17:81869231-81869231

 skinmalignant_melanomaSubstitution - coding silent

c.395C>T; p.T132M; 17:81869193-81869193

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.89C>A; p.P30Q; 17:81869842-81869842

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.468C>T; p.Y156Y; 17:81869023-81869023

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.597G>A; p.K199K; 17:81868894-81868894

 oesophagus; middle_thirdcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.48G>T; p.A16A; 17:81869883-81869883

 soft_tissue; striated_musclerhabdomyosarcomaSubstitution - coding silent