lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3916
Symbol	LAMP1
Synonymous	CD107a\|LAMPA\|LGP120
Full name	lysosomal-associated membrane protein 1
Gene description	CD107 antigen-like family member A\|LAMP-1\|lysosome-associated membrane glycoprotein 1\|lysosome-associated membrane protein 1
Cytoband	13q34
Gene type	protein-coding
Synonymous	MIM:153330; HGNC:HGNC:6499; Ensembl:ENSG00000185896; HPRD:01076; Vega:OTTHUMG00000017380

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.530C>T; p.A177V; 13:113310835-113310835	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.562+7C>T; p.?; 13:113310874-113310874	pancreas	carcinoma	Unknown
c.913C>T; p.Q305*; 13:113321440-113321440	skin	malignant_melanoma	Substitution - Nonsense
c.870C>T; p.F290F; 13:113320464-113320464	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.237C>T; p.S79S; 13:113309696-113309696	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - coding silent
c.1228A>C; p.S410R; 13:113322395-113322395	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.926T>C; p.I309T; 13:113321453-113321453	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.807C>T; p.C269C; 13:113320401-113320401	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.926T>C; p.I309T; 13:113321453-113321453	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - Missense
c.926T>C; p.I309T; 13:113321453-113321453	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.192C>A; p.T64T; 13:113309651-113309651	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.552C>T; p.F184F; 13:113310857-113310857	skin	malignant_melanoma	Substitution - coding silent
c.967G>A; p.G323S; 13:113321580-113321580	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.747_750+35del39; p.?; 13:113319653-113319691	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Unknown
c.1020G>A; p.A340A; 13:113321633-113321633	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.981G>A; p.A327A; 13:113321594-113321594	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1227G>T; p.R409S; 13:113322394-113322394	liver	carcinoma; hepatocellular_carcinoma	Substitution - Missense
c.183+6A>T; p.?; 13:113306612-113306612	pancreas	carcinoma	Unknown
c.897T>G; p.F299L; 13:113321424-113321424	stomach	carcinoma; intestinal_adenocarcinoma	Substitution - Missense
c.339C>A; p.V113V; 13:113309798-113309798	prostate	carcinoma	Substitution - coding silent
c.1195G>A; p.V399I; 13:113322362-113322362	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.112G>A; p.G38R; 13:113306535-113306535	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.386C>T; p.P129L; 13:113309845-113309845	NS	malignant_melanoma	Substitution - Missense
c.572G>T; p.C191F; 13:113319478-113319478	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1041G>A; p.T347T; 13:113321654-113321654	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - coding silent
c.236C>A; p.S79Y; 13:113309695-113309695	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.612G>A; p.A204A; 13:113319518-113319518	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.130G>A; p.A44T; 13:113306553-113306553	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.977G>A; p.R326Q; 13:113321590-113321590	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.935A>G; p.D312G; 13:113321462-113321462	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1046C>T; p.A349V; 13:113321659-113321659	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.163G>A; p.D55N; 13:113306586-113306586	NS	NS	Substitution - Missense
c.65T>C; p.L22P; 13:113306488-113306488	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.1021G>T; p.E341*; 13:113321634-113321634	lung; right_lower_lobe	carcinoma; adenocarcinoma	Substitution - Nonsense
c.611C>T; p.A204V; 13:113319517-113319517	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.853G>A; p.V285I; 13:113320447-113320447	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.611C>T; p.A204V; 13:113319517-113319517	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.349A>T; p.S117C; 13:113309808-113309808	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.996C>T; p.V332V; 13:113321609-113321609	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.314C>T; p.T105M; 13:113309773-113309773	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.535C>T; p.L179F; 13:113310840-113310840	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.205T>C; p.S69P; 13:113309664-113309664	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.507G>A; p.T169T; 13:113310812-113310812	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.507G>A; p.T169T; 13:113310812-113310812	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.29C>T; p.P10L; 13:113297463-113297463	bone; scapula	Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour	Substitution - Missense
c.1191C>T; p.L397L; 13:113322358-113322358	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.183G>T; p.K61N; 13:113306606-113306606	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1047G>A; p.A349A; 13:113321660-113321660	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1186G>A; p.V396I; 13:113322353-113322353	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.893G>T; p.R298L; 13:113321420-113321420	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1203C>T; p.I401I; 13:113322370-113322370	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - coding silent
c.337G>A; p.V113I; 13:113309796-113309796	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.178C>T; p.P60S; 13:113306601-113306601	skin	malignant_melanoma	Substitution - Missense
c.322G>A; p.A108T; 13:113309781-113309781	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.139T>C; p.S47P; 13:113306562-113306562	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.407T>G; p.I136S; 13:113310712-113310712	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.892C>T; p.R298W; 13:113321419-113321419	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.140C>G; p.S47C; 13:113306563-113306563	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.134A>G; p.N45S; 13:113306557-113306557	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma	Substitution - Missense
c.1169G>A; p.G390D; 13:113322336-113322336	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.236C>G; p.S79C; 13:113309695-113309695	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1019C>T; p.A340V; 13:113321632-113321632	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.947C>T; p.P316L; 13:113321560-113321560	urinary_tract; bladder	carcinoma	Substitution - Missense
c.966C>T; p.N322N; 13:113321579-113321579	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.966C>T; p.N322N; 13:113321579-113321579	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm; acute_myeloid_leukaemia	Substitution - coding silent
c.1033C>T; p.R345C; 13:113321646-113321646	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1033C>T; p.R345C; 13:113321646-113321646	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.744C>T; p.D248D; 13:113319650-113319650	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1003T>C; p.S335P; 13:113321616-113321616	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.1003T>C; p.S335P; 13:113321616-113321616	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.750+1G>A; p.?; 13:113319657-113319657	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.484C>A; p.H162N; 13:113310789-113310789	breast	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation