Cancer metastasis database

Annotation category 5

Gene information

Gene ID 390
Symbol

RND3

Synonymous

ARHE|Rho8|RhoE|memB

Full name

Rho family GTPase 3

Gene description

protein MemB|ras homolog gene family, member E|rho-related GTP-binding protein Rho8|rho-related GTP-binding protein RhoE|small GTP binding protein Rho8

Cytoband

2q23.3

Gene type

protein-coding

Synonymous

MIM:602924; HGNC:HGNC:671; Ensembl:ENSG00000115963; HPRD:04233; Vega:OTTHUMG00000131859

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.629C>T; p.S210L; 2:150470093-150470093

 central_nervous_system; braingliomaSubstitution - Missense

c.214G>T; p.E72*; 2:150486718-150486718

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.126C>G; p.V42V; 2:150487292-150487292

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.349-9delC; p.?; 2:150471770-150471770

 stomachcarcinoma; diffuse_adenocarcinomaUnknown

c.242C>A; p.S81Y; 2:150474981-150474981

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.637G>C; p.A213P; 2:150470085-150470085

 pancreaspancreatic_intraepithelial_neoplasia_(PanIN)Substitution - Missense

c.637G>C; p.A213P; 2:150470085-150470085

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.497C>T; p.A166V; 2:150470225-150470225

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.132C>T; p.A44A; 2:150487286-150487286

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.719G>T; p.S240I; 2:150470003-150470003

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.546G>A; p.S182S; 2:150470176-150470176

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - coding silent

c.306T>C; p.F102F; 2:150474917-150474917

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.588A>C; p.A196A; 2:150470134-150470134

 ovaryother; neoplasmSubstitution - coding silent

c.478G>A; p.D160N; 2:150471632-150471632

 prostatecarcinomaSubstitution - Missense

c.574G>A; p.V192I; 2:150470148-150470148

 boneEwings_sarcoma-peripheral_primitive_neuroectodermal_tumourSubstitution - Missense

c.144C>T; p.F48F; 2:150487274-150487274

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.194A>T; p.E65V; 2:150486738-150486738

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.284C>T; p.S95L; 2:150474939-150474939

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.284C>T; p.S95L; 2:150474939-150474939

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.284C>T; p.S95L; 2:150474939-150474939

 breastcarcinomaSubstitution - Missense

c.304T>A; p.F102I; 2:150474919-150474919

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.464C>T; p.T155M; 2:150471646-150471646

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.464C>T; p.T155M; 2:150471646-150471646

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.633G>A; p.Q211Q; 2:150470089-150470089

 breastcarcinomaSubstitution - coding silent

c.419G>A; p.R140Q; 2:150471691-150471691

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.71G>A; p.C24Y; 2:150487347-150487347

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.667A>G; p.R223G; 2:150470055-150470055

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.667A>G; p.R223G; 2:150470055-150470055

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.668G>T; p.R223I; 2:150470054-150470054

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.251A>G; p.Y84C; 2:150474972-150474972

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.520T>G; p.Y174D; 2:150470202-150470202

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.473C>T; p.S158F; 2:150471637-150471637

 skinmalignant_melanomaSubstitution - Missense

c.526G>A; p.E176K; 2:150470196-150470196

 breastcarcinomaSubstitution - Missense

c.28T>G; p.L10V; 2:150487390-150487390

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.347delA; p.K116fs*31; 2:150474876-150474876

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - Frameshift

c.194A>G; p.E65G; 2:150486738-150486738

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.194A>G; p.E65G; 2:150486738-150486738

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.693_694GG>TT; p.D232Y; 2:150470028-150470029

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.44T>G; p.I15S; 2:150487374-150487374

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.228G>T; p.W76C; 2:150486704-150486704

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.638C>T; p.A213V; 2:150470084-150470084

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.614T>G; p.V205G; 2:150470108-150470108

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.646C>T; p.R216W; 2:150470076-150470076

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.570T>C; p.F190F; 2:150470152-150470152

 skinmalignant_melanomaSubstitution - coding silent

c.415C>A; p.L139M; 2:150471695-150471695

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.681G>A; p.S227S; 2:150470041-150470041

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.697T>G; p.L233V; 2:150470025-150470025

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.199G>A; p.D67N; 2:150486733-150486733

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.388delA; p.M130fs*17; 2:150471722-150471722

 upper_aerodigestive_tract; head_neckcarcinoma; squamous_cell_carcinomaDeletion - Frameshift

c.419G>T; p.R140L; 2:150471691-150471691

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.198C>T; p.I66I; 2:150486734-150486734

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.198C>T; p.I66I; 2:150486734-150486734

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.555C>T; p.S185S; 2:150470167-150470167

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.377C>T; p.P126L; 2:150471733-150471733

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.268C>A; p.L90I; 2:150474955-150474955

 breastcarcinomaSubstitution - Missense