Cancer metastasis database

Annotation category 5

Gene information

Gene ID 384
Symbol

ARG2

Synonymous

-

Full name

arginase 2

Gene description

L-arginine amidinohydrolase|L-arginine ureahydrolase|arginase, type II|arginase-2, mitochondrial|kidney arginase|kidney-type arginase|non-hepatic arginase|nonhepatic arginase|type II arginase

Cytoband

14q24.1

Gene type

protein-coding

Synonymous

MIM:107830; HGNC:HGNC:664; Ensembl:ENSG00000081181; HPRD:00143; Vega:OTTHUMG00000171807

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.101C>T; p.S34L; 14:67620078-67620078

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.821G>A; p.R274Q; 14:67648145-67648145

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.71A>C; p.H24P; 14:67620048-67620048

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.890T>C; p.V297A; 14:67650745-67650745

 breastcarcinomaSubstitution - Missense

c.251A>T; p.N84I; 14:67642252-67642252

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.661G>T; p.D221Y; 14:67646964-67646964

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.18C>T; p.S6S; 14:67619995-67619995

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.1044T>C; p.N348N; 14:67650899-67650899

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.543T>G; p.F181L; 14:67646664-67646664

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.781C>T; p.P261S; 14:67648105-67648105

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.33C>G; p.L11L; 14:67620010-67620010

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.208G>T; p.D70Y; 14:67642209-67642209

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.296T>C; p.L99P; 14:67642297-67642297

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.116G>T; p.R39I; 14:67620898-67620898

 pancreascarcinomaSubstitution - Missense

c.586A>G; p.I196V; 14:67646707-67646707

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.1018C>T; p.P340S; 14:67650873-67650873

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.952G>T; p.V318L; 14:67650807-67650807

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.601G>A; p.V201M; 14:67646722-67646722

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.571G>C; p.A191P; 14:67646692-67646692

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.982G>T; p.E328*; 14:67650837-67650837

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.444C>T; p.I148I; 14:67645724-67645724

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.444C>T; p.I148I; 14:67645724-67645724

 livercarcinomaSubstitution - coding silent

c.618-10C>T; p.?; 14:67646911-67646911

 ovaryother; neoplasmUnknown

c.618-10C>T; p.?; 14:67646911-67646911

 ovaryother; neoplasmUnknown

c.618-10C>T; p.?; 14:67646911-67646911

 ovaryother; neoplasmUnknown

c.527C>A; p.P176Q; 14:67646648-67646648

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.162G>A; p.L54L; 14:67620944-67620944

 breastcarcinomaSubstitution - coding silent

c.151G>T; p.E51*; 14:67620933-67620933

 breastcarcinomaSubstitution - Nonsense

c.844G>A; p.E282K; 14:67648168-67648168

 skinmalignant_melanomaSubstitution - Missense

c.223C>G; p.P75A; 14:67642224-67642224

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.431C>T; p.A144V; 14:67645711-67645711

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.33C>T; p.L11L; 14:67620010-67620010

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.33C>T; p.L11L; 14:67620010-67620010

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.33C>T; p.L11L; 14:67620010-67620010

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.349_351delGGA; p.G117delG; 14:67642350-67642352

 large_intestine; coloncarcinoma; adenocarcinomaDeletion - In frame

c.432C>A; p.A144A; 14:67645712-67645712

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.613G>T; p.E205*; 14:67646734-67646734

 ovarycarcinoma; serous_carcinomaSubstitution - Nonsense

c.861G>C; p.G287G; 14:67650716-67650716

 skinmalignant_melanomaSubstitution - coding silent