Cancer metastasis database

Annotation category 5

Gene information

Gene ID 383
Symbol

ARG1

Synonymous

-

Full name

arginase 1

Gene description

arginase, liver|arginase-1|liver-type arginase|type I arginase

Cytoband

6q23

Gene type

protein-coding

Synonymous

MIM:608313; HGNC:HGNC:663; Ensembl:ENSG00000118520; HPRD:01947; Vega:OTTHUMG00000015566

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.270C>T; p.N90N; 6:131579250-131579250

 livercarcinoma; hepatocellular_carcinomaSubstitution - coding silent

c.270C>T; p.N90N; 6:131579250-131579250

 breastcarcinomaSubstitution - coding silent

c.620G>A; p.G207E; 6:131583119-131583119

 skin; legmalignant_melanomaSubstitution - Missense

c.892G>T; p.A298S; 6:131583831-131583831

 kidneycarcinoma; renal_cell_carcinomaSubstitution - Missense

c.646C>A; p.L216I; 6:131583145-131583145

 lungcarcinoma; small_cell_carcinomaSubstitution - Missense

c.669G>A; p.K223K; 6:131583358-131583358

 skinmalignant_melanomaSubstitution - coding silent

c.875C>T; p.T292I; 6:131583814-131583814

 skinmalignant_melanomaSubstitution - Missense

c.50A>C; p.K17T; 6:131573332-131573332

 livercarcinomaSubstitution - Missense

c.26G>A; p.G9E; 6:131573308-131573308

 skin; scalpcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.451G>A; p.E151K; 6:131581364-131581364

 skinmalignant_melanomaSubstitution - Missense

c.212G>T; p.R71M; 6:131579192-131579192

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.709G>A; p.D237N; 6:131583398-131583398

 NSmalignant_melanomaSubstitution - Missense

c.306-4A>G; p.?; 6:131581215-131581215

 central_nervous_system; brainglioma; astrocytoma_Grade_IVUnknown

c.7G>A; p.A3T; 6:131573289-131573289

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.7G>A; p.A3T; 6:131573289-131573289

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.7G>A; p.A3T; 6:131573289-131573289

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.769G>A; p.G257S; 6:131583458-131583458

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.486C>G; p.F162L; 6:131582641-131582641

 breastcarcinomaSubstitution - Missense

c.215C>A; p.S72Y; 6:131579195-131579195

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.630G>A; p.K210K; 6:131583129-131583129

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.465+1G>T; p.?; 6:131581379-131581379

 endometriumcarcinoma; endometrioid_carcinomaUnknown

c.73G>A; p.E25K; 6:131576678-131576678

 pancreascarcinoma; ductal_carcinomaSubstitution - Missense

c.73G>A; p.E25K; 6:131576678-131576678

 pancreascarcinomaSubstitution - Missense

c.47C>G; p.S16*; 6:131573329-131573329

 lungcarcinoma; adenocarcinomaSubstitution - Nonsense

c.45C>A; p.F15L; 6:131573327-131573327

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.45C>A; p.F15L; 6:131573327-131573327

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; chronic_lymphocytic_leukaemia-small_lymphocytic_lymphomaSubstitution - Missense

c.330C>T; p.G110G; 6:131581243-131581243

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.231C>T; p.S77S; 6:131579211-131579211

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.612C>A; p.D204E; 6:131583111-131583111

 livercarcinomaSubstitution - Missense

c.612C>A; p.D204E; 6:131583111-131583111

 livercarcinomaSubstitution - Missense

c.603T>C; p.T201T; 6:131583102-131583102

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.431C>T; p.P144L; 6:131581344-131581344

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.533G>A; p.G178D; 6:131582688-131582688

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.283C>A; p.L95M; 6:131579263-131579263

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.124G>T; p.E42*; 6:131576729-131576729

 large_intestinecarcinoma; adenocarcinomaSubstitution - Nonsense

c.57G>A; p.Q19Q; 6:131573339-131573339

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.340G>A; p.V114I; 6:131581253-131581253

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.446T>A; p.L149Q; 6:131581359-131581359

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.335C>T; p.A112V; 6:131581248-131581248

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.134G>A; p.C45Y; 6:131579114-131579114

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.751G>A; p.G251S; 6:131583440-131583440

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.905C>T; p.A302V; 6:131583844-131583844

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.295G>A; p.G99R; 6:131579275-131579275

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.609G>A; p.V203V; 6:131583108-131583108

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.849G>A; p.G283G; 6:131583788-131583788

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.685C>A; p.L229I; 6:131583374-131583374

 breastcarcinomaSubstitution - Missense

c.271G>A; p.G91R; 6:131579251-131579251

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.360C>A; p.V120V; 6:131581273-131581273

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.360C>A; p.V120V; 6:131581273-131581273

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.58C>T; p.P20S; 6:131576663-131576663

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.251T>A; p.V84E; 6:131579231-131579231

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.913G>A; p.G305R; 6:131583852-131583852

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.32T>C; p.I11T; 6:131573314-131573314

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.62G>A; p.R21Q; 6:131576667-131576667

 breastcarcinomaSubstitution - Missense

c.12G>A; p.K4K; 6:131573294-131573294

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - coding silent

c.497C>T; p.T166I; 6:131582652-131582652

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.632T>G; p.V211G; 6:131583131-131583131

 breastcarcinomaSubstitution - Missense

c.70G>T; p.V24L; 6:131576675-131576675

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.774C>G; p.L258L; 6:131583463-131583463

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - coding silent

c.774C>G; p.L258L; 6:131583463-131583463

 urinary_tract; bladdercarcinomaSubstitution - coding silent

c.70G>T; p.V24L; 6:131576675-131576675

 ovarycarcinoma; serous_carcinomaSubstitution - Missense

c.703G>A; p.G235R; 6:131583392-131583392

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.949T>G; p.Y317D; 6:131583888-131583888

 large_intestinecarcinoma; adenocarcinomaSubstitution - Missense

c.475G>A; p.V159M; 6:131582630-131582630

 central_nervous_system; brainprimitive_neuroectodermal_tumour-medulloblastomaSubstitution - Missense

c.425G>A; p.G142E; 6:131581338-131581338

 skinmalignant_melanomaSubstitution - Missense