Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3820
Symbol

KLRB1

Synonymous

CD161|CLEC5B|NKR|NKR-P1|NKR-P1A|NKRP1A|hNKR-P1A

Full name

killer cell lectin-like receptor subfamily B, member 1

Gene description

C-type lectin domain family 5 member B|killer cell lectin-like receptor subfamily B member 1|natural killer cell surface protein P1A

Cytoband

12p13

Gene type

protein-coding

Synonymous

MIM:602890; HGNC:HGNC:6373; HPRD:04201

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.376G>T; p.E126*; 12:9598537-9598537

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.459G>A; p.W153*; 12:9598117-9598117

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Nonsense

c.582G>A; p.Q194Q; 12:9595370-9595370

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.582G>A; p.Q194Q; 12:9595370-9595370

 breastcarcinomaSubstitution - coding silent

c.388C>T; p.L130L; 12:9598525-9598525

 pancreascarcinomaSubstitution - coding silent

c.388C>T; p.L130L; 12:9598525-9598525

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.507C>T; p.N169N; 12:9598069-9598069

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.60T>G; p.S20R; 12:9607780-9607780

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.383G>C; p.S128T; 12:9598530-9598530

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.451_452delCT; p.L151fs*25; 12:9598124-9598125

 breastcarcinomaDeletion - Frameshift

c.304C>A; p.R102R; 12:9598609-9598609

 lungcarcinoma; adenocarcinomaSubstitution - coding silent

c.125A>G; p.K42R; 12:9601560-9601560

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.646C>A; p.P216T; 12:9595306-9595306

 kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - Missense

c.411A>G; p.E137E; 12:9598502-9598502

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.561C>T; p.N187N; 12:9595391-9595391

 livercarcinomaSubstitution - coding silent

c.561C>T; p.N187N; 12:9595391-9595391

 livercarcinomaSubstitution - coding silent

c.103C>G; p.P35A; 12:9601582-9601582

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.128T>A; p.L43H; 12:9601557-9601557

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.99T>C; p.G33G; 12:9601586-9601586

 large_intestinecarcinoma; adenocarcinomaSubstitution - coding silent

c.601T>C; p.Y201H; 12:9595351-9595351

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.307G>A; p.E103K; 12:9598606-9598606

 thyroidother; neoplasmSubstitution - Missense

c.573C>A; p.S191S; 12:9595379-9595379

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.500G>A; p.W167*; 12:9598076-9598076

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.441C>A; p.D147E; 12:9598135-9598135

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.55G>A; p.E19K; 12:9607785-9607785

 skinmalignant_melanomaSubstitution - Missense

c.112C>A; p.Q38K; 12:9601573-9601573

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.83G>A; p.R28Q; 12:9607757-9607757

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.337A>G; p.N113D; 12:9598576-9598576

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.380C>T; p.S127F; 12:9598533-9598533

 skinmalignant_melanomaSubstitution - Missense

c.82C>T; p.R28W; 12:9607758-9607758

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.674C>G; p.S225C; 12:9595278-9595278

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.674C>G; p.S225C; 12:9595278-9595278

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.128T>G; p.L43R; 12:9601557-9601557

 oesophagus; lower_thirdcarcinoma; adenocarcinomaSubstitution - Missense

c.128T>G; p.L43R; 12:9601557-9601557

 oesophaguscarcinoma; adenocarcinomaSubstitution - Missense

c.260-10_311del62; p.?; 12:9598602-9598663

 stomachcarcinoma; intestinal_adenocarcinomaUnknown

c.480A>T; p.L160F; 12:9598096-9598096

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.637G>T; p.E213*; 12:9595315-9595315

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Nonsense

c.637G>T; p.E213*; 12:9595315-9595315

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Nonsense

c.468A>T; p.L156F; 12:9598108-9598108

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.451C>T; p.L151L; 12:9598125-9598125

 thyroidother; neoplasmSubstitution - coding silent

c.243C>A; p.S81R; 12:9599783-9599783

 urinary_tract; bladdercarcinomaSubstitution - Missense

c.16A>G; p.I6V; 12:9607824-9607824

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.431T>C; p.L144P; 12:9598145-9598145

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.431T>C; p.L144P; 12:9598145-9598145

 urinary_tract; bladdercarcinomaSubstitution - Missense