lung cancer gene and literature database Home

Annotation category 5

Basic annotation
Ontology and pathways
Literature evidence
Curated literatures
Expression
Gene expression chart
Somatic mutation
COSMIC and TCGA mutations
Network
Gene interaction
ceRNA
Gene-related ceRNA

Gene information

Gene ID	3689
Symbol	ITGB2
Synonymous	CD18\|LAD\|LCAMB\|LFA-1\|MAC-1\|MF17\|MFI7
Full name	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
Gene description	cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor)\|complement receptor C3 beta-subunit\|integrin beta chain, beta 2\|integrin beta-2\|leukocyte cell adhesion molecule CD18\|leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C
Cytoband	21q22.3
Gene type	protein-coding
Synonymous	MIM:600065; HGNC:HGNC:6155; Ensembl:ENSG00000160255; HPRD:02506; Vega:OTTHUMG00000090257

COSMIC somatic mutation

Mutation (CDS; AA; Chr)	Site	Histology	Mutation Type
c.28G>A; p.A10T; 21:44910755-44910755	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.741G>T; p.P247P; 21:44901492-44901492	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.1237G>A; p.V413M; 21:44891984-44891984	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.700G>C; p.E234Q; 21:44901533-44901533	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2188A>G; p.S730G; 21:44886795-44886795	urinary_tract; bladder	carcinoma	Substitution - Missense
c.750C>T; p.I250I; 21:44900467-44900467	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1869C>G; p.G623G; 21:44889284-44889284	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.221C>T; p.A74V; 21:44907022-44907022	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.221C>T; p.A74V; 21:44907022-44907022	upper_aerodigestive_tract; mouth	carcinoma	Substitution - Missense
c.221C>T; p.A74V; 21:44907022-44907022	upper_aerodigestive_tract; mouth	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.892G>A; p.E298K; 21:44900325-44900325	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.178A>C; p.I60L; 21:44907065-44907065	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.2099A>G; p.N700S; 21:44886884-44886884	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2099A>G; p.N700S; 21:44886884-44886884	skin	malignant_melanoma	Substitution - Missense
c.2228T>G; p.L743R; 21:44886755-44886755	kidney	carcinoma; papillary_renal_cell_carcinoma	Substitution - Missense
c.362G>A; p.R121Q; 21:44903502-44903502	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.540_564del25; p.N181fs*20; 21:44901669-44901693	breast	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.1412+1G>A; p.?; 21:44891808-44891808	lung; right_upper_lobe	carcinoma; adenocarcinoma	Unknown
c.2078G>A; p.R693Q; 21:44888695-44888695	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.638A>G; p.N213S; 21:44901595-44901595	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.2240G>T; p.W747L; 21:44886743-44886743	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1756C>T; p.R586W; 21:44889397-44889397	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.333G>A; p.Q111Q; 21:44903531-44903531	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	Substitution - coding silent
c.194G>A; p.R65Q; 21:44907049-44907049	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.612C>T; p.F204F; 21:44901621-44901621	urinary_tract; bladder	carcinoma	Substitution - coding silent
c.829G>T; p.A277S; 21:44900388-44900388	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.905C>A; p.P302Q; 21:44899155-44899155	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.905C>A; p.P302Q; 21:44899155-44899155	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1880C>T; p.S627F; 21:44888893-44888893	breast	carcinoma	Substitution - Missense
c.897C>T; p.F299F; 21:44900320-44900320	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.708G>C; p.G236G; 21:44901525-44901525	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.818G>A; p.G273E; 21:44900399-44900399	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1903G>A; p.E635K; 21:44888870-44888870	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.537C>T; p.F179F; 21:44901696-44901696	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.603G>A; p.P201P; 21:44901630-44901630	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1903G>A; p.E635K; 21:44888870-44888870	skin	malignant_melanoma	Substitution - Missense
c.1227C>A; p.I409I; 21:44891994-44891994	breast	carcinoma	Substitution - coding silent
c.2024C>T; p.T675M; 21:44888749-44888749	pancreas	carcinoma	Substitution - Missense
c.488C>T; p.S163F; 21:44903376-44903376	skin	malignant_melanoma	Substitution - Missense
c.1586T>C; p.I529T; 21:44890049-44890049	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.663C>T; p.V221V; 21:44901570-44901570	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.994-1G>A; p.?; 21:44895061-44895061	skin; head_neck	carcinoma; squamous_cell_carcinoma	Unknown
c.2247+4A>C; p.?; 21:44886732-44886732	pancreas	carcinoma	Unknown
c.2241G>A; p.W747*; 21:44886742-44886742	skin	malignant_melanoma	Substitution - Nonsense
c.2129C>T; p.A710V; 21:44886854-44886854	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.22C>T; p.L8L; 21:44910761-44910761	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.769C>T; p.R257W; 21:44900448-44900448	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.807C>T; p.F269F; 21:44900410-44900410	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1788C>T; p.C596C; 21:44889365-44889365	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1011C>A; p.I337I; 21:44895043-44895043	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.311C>T; p.T104M; 21:44906932-44906932	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.659A>C; p.E220A; 21:44901574-44901574	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1935G>T; p.A645A; 21:44888838-44888838	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.659A>C; p.E220A; 21:44901574-44901574	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1813delT; p.S605fs*28; 21:44889340-44889340	skin; neck	malignant_melanoma	Deletion - Frameshift
c.2122A>T; p.T708S; 21:44886861-44886861	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1989G>A; p.K663K; 21:44888784-44888784	breast	carcinoma	Substitution - coding silent
c.169C>T; p.P57S; 21:44907074-44907074	skin	malignant_melanoma	Substitution - Missense
c.811G>A; p.G271S; 21:44900406-44900406	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.790G>T; p.D264Y; 21:44900427-44900427	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.285G>A; p.Q95Q; 21:44906958-44906958	skin	malignant_melanoma	Substitution - coding silent
c.770_772delGGC; p.R257delR; 21:44900445-44900447	endometrium	carcinoma; endometrioid_carcinoma	Deletion - In frame
c.522G>T; p.K174N; 21:44901711-44901711	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1697C>T; p.P566L; 21:44889456-44889456	skin; extremity	malignant_melanoma	Substitution - Missense
c.817G>A; p.G273R; 21:44900400-44900400	skin	malignant_melanoma	Substitution - Missense
c.1111C>T; p.H371Y; 21:44893517-44893517	skin	malignant_melanoma	Substitution - Missense
c.2141T>C; p.L714P; 21:44886842-44886842	skin	malignant_melanoma	Substitution - Missense
c.112G>A; p.E38K; 21:44910319-44910319	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1798G>T; p.V600L; 21:44889355-44889355	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.824T>C; p.L275P; 21:44900393-44900393	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.2203T>A; p.Y735N; 21:44886780-44886780	skin	malignant_melanoma	Substitution - Missense
c.1003G>A; p.E335K; 21:44895051-44895051	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.843delC; p.N282fs*41; 21:44900374-44900374	lung	carcinoma; small_cell_carcinoma	Deletion - Frameshift
c.2275A>G; p.T759A; 21:44886403-44886403	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.2275A>G; p.T759A; 21:44886403-44886403	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.909G>A; p.S303S; 21:44899151-44899151	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.1483G>A; p.G495R; 21:44890152-44890152	skin	malignant_melanoma	Substitution - Missense
c.1063C>A; p.L355I; 21:44894991-44894991	liver	carcinoma	Substitution - Missense
c.816C>T; p.D272D; 21:44900401-44900401	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.816C>T; p.D272D; 21:44900401-44900401	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.538G>A; p.V180M; 21:44901695-44901695	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.2200G>A; p.E734K; 21:44886783-44886783	skin; head_neck	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.563G>A; p.R188Q; 21:44901670-44901670	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.529C>T; p.L177L; 21:44901704-44901704	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.729C>G; p.V243V; 21:44901504-44901504	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - coding silent
c.2010C>T; p.C670C; 21:44888763-44888763	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.547C>T; p.H183Y; 21:44901686-44901686	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.547C>T; p.H183Y; 21:44901686-44901686	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.1809C>A; p.C603*; 21:44889344-44889344	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1571T>A; p.V524D; 21:44890064-44890064	breast	carcinoma	Substitution - Missense
c.899A>G; p.D300G; 21:44899161-44899161	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.248G>A; p.S83N; 21:44906995-44906995	skin	malignant_melanoma	Substitution - Missense
c.2070T>C; p.D690D; 21:44888703-44888703	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.539_563del25; p.V180fs*21; 21:44901670-44901694	breast	carcinoma; ductal_carcinoma	Deletion - Frameshift
c.29C>T; p.A10V; 21:44910754-44910754	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1285C>T; p.R429W; 21:44891936-44891936	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1975G>T; p.G659C; 21:44888798-44888798	lung	carcinoma; adenocarcinoma	Substitution - Missense
c.1039G>C; p.E347Q; 21:44895015-44895015	lung; right_upper_lobe	carcinoma; adenocarcinoma	Substitution - Missense
c.465G>C; p.R155R; 21:44903399-44903399	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1963A>C; p.N655H; 21:44888810-44888810	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>A; p.A85T; 21:44906990-44906990	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>A; p.A85T; 21:44906990-44906990	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.253G>A; p.A85T; 21:44906990-44906990	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2209C>T; p.R737C; 21:44886774-44886774	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.2209C>T; p.R737C; 21:44886774-44886774	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Missense
c.849C>T; p.D283D; 21:44900368-44900368	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1317G>A; p.V439V; 21:44891904-44891904	ovary	carcinoma; serous_carcinoma	Substitution - coding silent
c.1602C>T; p.C534C; 21:44890033-44890033	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1602C>T; p.C534C; 21:44890033-44890033	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1602C>T; p.C534C; 21:44890033-44890033	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1173G>A; p.T391T; 21:44893455-44893455	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.24G>T; p.L8L; 21:44910759-44910759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.24G>T; p.L8L; 21:44910759-44910759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1220T>C; p.V407A; 21:44893408-44893408	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.2220G>A; p.K740K; 21:44886763-44886763	skin	malignant_melanoma	Substitution - coding silent
c.24G>T; p.L8L; 21:44910759-44910759	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.793G>T; p.D265Y; 21:44900424-44900424	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1243G>A; p.V415I; 21:44891978-44891978	breast	carcinoma	Substitution - Missense
c.158G>T; p.G53V; 21:44907085-44907085	pancreas	carcinoma	Substitution - Missense
c.410A>G; p.Y137C; 21:44903454-44903454	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1286G>T; p.R429L; 21:44891935-44891935	skin	malignant_melanoma	Substitution - Missense
c.1267G>A; p.E423K; 21:44891954-44891954	skin; trunk	malignant_melanoma; nodular	Substitution - Missense
c.2268C>T; p.S756S; 21:44886410-44886410	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.2268C>T; p.S756S; 21:44886410-44886410	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2268C>T; p.S756S; 21:44886410-44886410	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.828C>T; p.G276G; 21:44900389-44900389	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.2025G>T; p.T675T; 21:44888748-44888748	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.740C>T; p.P247L; 21:44901493-44901493	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.1192G>T; p.G398C; 21:44893436-44893436	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.195G>A; p.R65R; 21:44907048-44907048	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.77C>T; p.T26M; 21:44910354-44910354	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.1545G>T; p.G515G; 21:44890090-44890090	lung	carcinoma; squamous_cell_carcinoma	Substitution - coding silent
c.77C>T; p.T26M; 21:44910354-44910354	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.937G>T; p.E313*; 21:44899123-44899123	breast	carcinoma	Substitution - Nonsense
c.1161C>T; p.S387S; 21:44893467-44893467	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.733G>A; p.A245T; 21:44901500-44901500	pancreas	carcinoma	Substitution - Missense
c.2004G>A; p.E668E; 21:44888769-44888769	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.454G>A; p.D152N; 21:44903410-44903410	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.2210G>A; p.R737H; 21:44886773-44886773	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.828C>A; p.G276G; 21:44900389-44900389	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1367G>A; p.R456H; 21:44891854-44891854	ovary	carcinoma; clear_cell_carcinoma	Substitution - Missense
c.1499A>G; p.D500G; 21:44890136-44890136	breast	carcinoma	Substitution - Missense
c.732C>T; p.A244A; 21:44901501-44901501	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1508C>T; p.S503F; 21:44890127-44890127	skin	malignant_melanoma	Substitution - Missense
c.1969G>A; p.V657M; 21:44888804-44888804	pancreas	carcinoma	Substitution - Missense
c.597G>A; p.Q199Q; 21:44901636-44901636	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.1024G>A; p.V342M; 21:44895030-44895030	urinary_tract; bladder	carcinoma	Substitution - Missense
c.1529G>A; p.G510E; 21:44890106-44890106	kidney	carcinoma; clear_cell_renal_cell_carcinoma	Substitution - Missense
c.967A>G; p.T323A; 21:44899093-44899093	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1548G>A; p.Q516Q; 21:44890087-44890087	skin	malignant_melanoma	Substitution - coding silent
c.2007C>A; p.G669G; 21:44888766-44888766	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.2123C>T; p.T708I; 21:44886860-44886860	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1835G>T; p.C612F; 21:44889318-44889318	lung	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.13C>T; p.R5C; 21:44910770-44910770	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - Missense
c.768G>A; p.T256T; 21:44900449-44900449	central_nervous_system; brain	glioma	Substitution - coding silent
c.528G>T; p.V176V; 21:44901705-44901705	lung	carcinoma; small_cell_carcinoma	Substitution - coding silent
c.1846C>T; p.P616S; 21:44889307-44889307	skin	malignant_melanoma	Substitution - Missense
c.411C>A; p.Y137*; 21:44903453-44903453	large_intestine; rectum	carcinoma; adenocarcinoma	Substitution - Nonsense
c.962C>T; p.A321V; 21:44899098-44899098	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.533C>T; p.P178L; 21:44901700-44901700	oesophagus	carcinoma; adenocarcinoma	Substitution - Missense
c.1757G>A; p.R586Q; 21:44889396-44889396	stomach	carcinoma; diffuse_adenocarcinoma	Substitution - Missense
c.1323T>C; p.V441V; 21:44891898-44891898	liver	carcinoma; hepatocellular_carcinoma	Substitution - coding silent
c.1757G>A; p.R586Q; 21:44889396-44889396	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1798G>A; p.V600I; 21:44889355-44889355	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1798G>A; p.V600I; 21:44889355-44889355	central_nervous_system; brain	glioma	Substitution - Missense
c.2112C>T; p.I704I; 21:44886871-44886871	breast	carcinoma	Substitution - coding silent
c.682G>A; p.G228R; 21:44901551-44901551	skin; scalp	carcinoma; squamous_cell_carcinoma	Substitution - Missense
c.1315G>A; p.V439M; 21:44891906-44891906	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1315G>A; p.V439M; 21:44891906-44891906	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1223C>T; p.P408L; 21:44893405-44893405	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1725C>T; p.C575C; 21:44889428-44889428	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.1143C>A; p.T381T; 21:44893485-44893485	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.898G>C; p.D300H; 21:44899162-44899162	ovary	carcinoma; serous_carcinoma	Substitution - Missense
c.1597T>C; p.Y533H; 21:44890038-44890038	large_intestine	carcinoma; adenocarcinoma	Substitution - Missense
c.829G>A; p.A277T; 21:44900388-44900388	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1493G>A; p.R498Q; 21:44890142-44890142	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1849G>A; p.G617S; 21:44889304-44889304	skin	malignant_melanoma	Substitution - Missense
c.489C>T; p.S163S; 21:44903375-44903375	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.39G>A; p.G13G; 21:44910744-44910744	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - coding silent
c.1289C>T; p.A430V; 21:44891932-44891932	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.846C>T; p.N282N; 21:44900371-44900371	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1958C>T; p.S653L; 21:44888815-44888815	oesophagus; lower_third	carcinoma; adenocarcinoma	Substitution - Missense
c.1289C>T; p.A430V; 21:44891932-44891932	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Substitution - Missense
c.1546C>T; p.Q516*; 21:44890089-44890089	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Nonsense
c.1546C>T; p.Q516*; 21:44890089-44890089	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Nonsense
c.1366C>T; p.R456C; 21:44891855-44891855	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.1037C>G; p.S346C; 21:44895017-44895017	liver	carcinoma	Substitution - Missense
c.1037C>G; p.S346C; 21:44895017-44895017	liver	carcinoma	Substitution - Missense
c.2132G>A; p.G711D; 21:44886851-44886851	urinary_tract; bladder	carcinoma	Substitution - Missense
c.897+1G>A; p.?; 21:44900319-44900319	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.897+1G>A; p.?; 21:44900319-44900319	large_intestine; rectum	carcinoma; adenocarcinoma	Unknown
c.897+1G>A; p.?; 21:44900319-44900319	central_nervous_system; brain	glioma; astrocytoma_Grade_IV	Unknown
c.187G>A; p.D63N; 21:44907056-44907056	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.808G>A; p.A270T; 21:44900409-44900409	stomach	carcinoma; adenocarcinoma	Substitution - Missense
c.1101C>A; p.V367V; 21:44893527-44893527	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - coding silent
c.2301T>A; p.A767A; 21:44886377-44886377	breast	carcinoma	Substitution - coding silent
c.1609G>A; p.D537N; 21:44890026-44890026	breast	carcinoma	Substitution - Missense
c.1686C>T; p.C562C; 21:44889467-44889467	large_intestine	carcinoma; adenocarcinoma	Substitution - coding silent
c.1635C>T; p.N545N; 21:44890000-44890000	large_intestine; caecum	carcinoma; adenocarcinoma	Substitution - coding silent
c.1635C>T; p.N545N; 21:44890000-44890000	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.1165G>A; p.G389R; 21:44893463-44893463	skin	malignant_melanoma	Substitution - Missense
c.1902C>T; p.F634F; 21:44888871-44888871	skin	malignant_melanoma	Substitution - coding silent
c.811G>T; p.G271C; 21:44900406-44900406	prostate	carcinoma; adenocarcinoma	Substitution - Missense
c.1627C>T; p.R543C; 21:44890008-44890008	endometrium	carcinoma; endometrioid_carcinoma	Substitution - Missense
c.575C>A; p.P192H; 21:44901658-44901658	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.1146C>T; p.Y382Y; 21:44893482-44893482	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.474C>T; p.N158N; 21:44903390-44903390	stomach	carcinoma; adenocarcinoma	Substitution - coding silent
c.78G>A; p.T26T; 21:44910353-44910353	endometrium	carcinoma; endometrioid_carcinoma	Substitution - coding silent
c.78G>A; p.T26T; 21:44910353-44910353	lung	carcinoma; adenocarcinoma	Substitution - coding silent
c.1778G>A; p.R593H; 21:44889375-44889375	large_intestine; colon	carcinoma; adenocarcinoma	Substitution - Missense
c.78G>A; p.T26T; 21:44910353-44910353	breast	carcinoma	Substitution - coding silent
c.306delA; p.V103fs*1; 21:44906937-44906937	large_intestine; caecum	carcinoma; adenocarcinoma	Deletion - Frameshift
c.1848delC; p.G617fs*16; 21:44889305-44889305	large_intestine	carcinoma; adenocarcinoma	Deletion - Frameshift
c.306delA; p.V103fs*1; 21:44906937-44906937	large_intestine; colon	carcinoma; adenocarcinoma	Deletion - Frameshift
c.2310G>T; p.*770Y; 21:44886368-44886368	breast	carcinoma	Nonstop extension
c.100C>T; p.R34W; 21:44910331-44910331	oesophagus	carcinoma	Substitution - Missense

Annotation category 5

Basic annotation

Literature evidence

Expression

Somatic mutation

Network

ceRNA

Gene information

COSMIC somatic mutation