Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3630
Symbol

INS

Synonymous

IDDM|IDDM1|IDDM2|ILPR|IRDN|MODY10

Full name

insulin

Gene description

preproinsulin|proinsulin

Cytoband

11p15.5

Gene type

protein-coding

Synonymous

MIM:176730; HGNC:HGNC:6081; Ensembl:ENSG00000254647; HPRD:01455; Vega:OTTHUMG00000009558

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.280C>A; p.Q94K; 11:2159905-2159905

kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - Missense

c.86A>C; p.H29P; 11:2160886-2160886

breastcarcinomaSubstitution - Missense

c.16C>T; p.R6C; 11:2160956-2160956

urinary_tract; bladdercarcinomaSubstitution - Missense

c.133G>A; p.E45K; 11:2160839-2160839

skinmalignant_melanomaSubstitution - Missense

c.333G>A; p.*111*; 11:2159852-2159852

central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - coding silent

c.129C>T; p.C43C; 11:2160843-2160843

kidneycarcinoma; clear_cell_renal_cell_carcinomaSubstitution - coding silent

c.129C>T; p.C43C; 11:2160843-2160843

haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - coding silent

c.129C>T; p.C43C; 11:2160843-2160843

haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemia_therapy_relatedSubstitution - coding silent

c.159G>A; p.K53K; 11:2160813-2160813

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.94G>C; p.G32R; 11:2160878-2160878

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.175G>A; p.E59K; 11:2160797-2160797

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.318G>T; p.E106D; 11:2159867-2159867

endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.228C>G; p.S76R; 11:2159957-2159957

central_nervous_system; brainglioma; astrocytoma_Grade_IVSubstitution - Missense

c.246G>T; p.L82L; 11:2159939-2159939

lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.34G>T; p.A12S; 11:2160938-2160938

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.105G>A; p.L35L; 11:2160867-2160867

skinmalignant_melanomaSubstitution - coding silent

c.276G>A; p.V92V; 11:2159909-2159909

endometriumcarcinoma; endometrioid_carcinomaSubstitution - coding silent

c.277G>A; p.E93K; 11:2159908-2159908

lungcarcinoma; adenocarcinomaSubstitution - Missense

c.121C>T; p.L41L; 11:2160851-2160851

prostatecarcinoma; adenocarcinomaSubstitution - coding silent

c.255C>T; p.S85S; 11:2159930-2159930

skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.217G>T; p.G73C; 11:2159968-2159968

large_intestinecarcinoma; adenocarcinomaSubstitution - Missense