Cancer metastasis database

Annotation category 5

Gene information

Gene ID 3626
Symbol

INHBC

Synonymous

IHBC

Full name

inhibin, beta C

Gene description

activin beta-C chain|inhibin beta C chain

Cytoband

12q13.1

Gene type

protein-coding

Synonymous

MIM:601233; HGNC:HGNC:6068; HPRD:03136

COSMIC somatic mutation

Mutation (CDS; AA; Chr)

Site

Histology

Mutation Type

c.814G>A; p.A272T; 12:57449777-57449777

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - Missense

c.814G>A; p.A272T; 12:57449777-57449777

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.745C>T; p.R249*; 12:57449708-57449708

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.299G>A; p.S100N; 12:57435185-57435185

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.843A>G; p.P281P; 12:57449806-57449806

 lungcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.466G>T; p.G156C; 12:57449429-57449429

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.277G>A; p.E93K; 12:57435163-57435163

 skinmalignant_melanomaSubstitution - Missense

c.950_951GT>AG; p.C317*; 12:57449913-57449914

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.879C>T; p.S293S; 12:57449842-57449842

 skinmalignant_melanomaSubstitution - coding silent

c.733A>G; p.R245G; 12:57449696-57449696

 thyroidcarcinomaSubstitution - Missense

c.811T>C; p.Y271H; 12:57449774-57449774

 livercarcinomaSubstitution - Missense

c.498T>C; p.T166T; 12:57449461-57449461

 breastcarcinoma; ductal_carcinomaSubstitution - coding silent

c.498T>C; p.T166T; 12:57449461-57449461

 breastcarcinoma; ductal_carcinomaSubstitution - coding silent

c.405G>A; p.M135I; 12:57449368-57449368

 ovaryother; neoplasmSubstitution - Missense

c.204C>T; p.S68S; 12:57435090-57435090

 skinmalignant_melanomaSubstitution - coding silent

c.795C>T; p.I265I; 12:57449758-57449758

 skinmalignant_melanomaSubstitution - coding silent

c.408C>A; p.F136L; 12:57449371-57449371

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.986A>G; p.Y329C; 12:57449949-57449949

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.838T>C; p.C280R; 12:57449801-57449801

 oesophaguscarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.986A>G; p.Y329C; 12:57449949-57449949

 livercarcinoma; hepatocellular_carcinomaSubstitution - Missense

c.927C>A; p.G309G; 12:57449890-57449890

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; essential_thrombocythaemiaSubstitution - coding silent

c.829A>T; p.I277L; 12:57449792-57449792

 lungcarcinoma; squamous_cell_carcinomaSubstitution - Missense

c.855A>C; p.A285A; 12:57449818-57449818

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.337C>A; p.R113S; 12:57449300-57449300

 lung; right_lower_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.105A>G; p.E35E; 12:57434991-57434991

 skinmalignant_melanomaSubstitution - coding silent

c.421C>T; p.P141S; 12:57449384-57449384

 skinmalignant_melanomaSubstitution - Missense

c.792G>A; p.W264*; 12:57449755-57449755

 skinmalignant_melanomaSubstitution - Nonsense

c.588C>A; p.T196T; 12:57449551-57449551

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.40C>T; p.P14S; 12:57434926-57434926

 skinmalignant_melanomaSubstitution - Missense

c.959C>T; p.T320M; 12:57449922-57449922

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.959C>T; p.T320M; 12:57449922-57449922

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.959C>T; p.T320M; 12:57449922-57449922

 stomachcarcinoma; intestinal_adenocarcinomaSubstitution - Missense

c.959C>T; p.T320M; 12:57449922-57449922

 stomachadenocarcinomaSubstitution - Missense

c.875C>A; p.A292D; 12:57449838-57449838

 urinary_tract; bladdercarcinoma; transitional_cell_carcinomaSubstitution - Missense

c.574C>T; p.Q192*; 12:57449537-57449537

 breastcarcinomaSubstitution - Nonsense

c.813C>T; p.Y271Y; 12:57449776-57449776

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.813C>T; p.Y271Y; 12:57449776-57449776

 large_intestine; caecumcarcinoma; adenocarcinomaSubstitution - coding silent

c.813C>T; p.Y271Y; 12:57449776-57449776

 stomachcarcinoma; adenocarcinomaSubstitution - coding silent

c.815C>T; p.A272V; 12:57449778-57449778

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.832G>T; p.G278W; 12:57449795-57449795

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.734G>A; p.R245K; 12:57449697-57449697

 skinmalignant_melanomaSubstitution - Missense

c.862C>T; p.P288S; 12:57449825-57449825

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.69C>T; p.G23G; 12:57434955-57434955

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - coding silent

c.835C>T; p.Q279*; 12:57449798-57449798

 stomachcarcinoma; adenocarcinomaSubstitution - Nonsense

c.488C>T; p.T163I; 12:57449451-57449451

 skinmalignant_melanomaSubstitution - Missense

c.705A>T; p.R235R; 12:57449668-57449668

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - coding silent

c.431_432CC>GA; p.T144R; 12:57449394-57449395

 lung; right_upper_lobecarcinoma; adenocarcinomaSubstitution - Missense

c.510G>A; p.L170L; 12:57449473-57449473

 skin; head_neckcarcinoma; squamous_cell_carcinomaSubstitution - coding silent

c.961G>A; p.A321T; 12:57449924-57449924

 skinmalignant_melanomaSubstitution - Missense

c.787G>A; p.D263N; 12:57449750-57449750

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.521C>T; p.A174V; 12:57449484-57449484

 prostatecarcinoma; adenocarcinomaSubstitution - Missense

c.564T>C; p.A188A; 12:57449527-57449527

 stomachadenocarcinomaSubstitution - coding silent

c.1014G>T; p.K338N; 12:57449977-57449977

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.608G>A; p.G203D; 12:57449571-57449571

 skinmalignant_melanomaSubstitution - Missense

c.642A>T; p.G214G; 12:57449605-57449605

 haematopoietic_and_lymphoid_tissuelymphoid_neoplasm; mantle_cell_lymphomaSubstitution - coding silent

c.81A>C; p.P27P; 12:57434967-57434967

 kidneycarcinoma; papillary_renal_cell_carcinomaSubstitution - coding silent

c.1005C>G; p.N335K; 12:57449968-57449968

 stomachcarcinoma; adenocarcinomaSubstitution - Missense

c.715G>A; p.D239N; 12:57449678-57449678

 skinmalignant_melanomaSubstitution - Missense

c.616G>A; p.A206T; 12:57449579-57449579

 endometriumcarcinoma; endometrioid_carcinomaSubstitution - Missense

c.24C>T; p.A8A; 12:57434910-57434910

 skinmalignant_melanomaSubstitution - coding silent

c.24C>T; p.A8A; 12:57434910-57434910

 skinmalignant_melanomaSubstitution - coding silent

c.216G>C; p.L72F; 12:57435102-57435102

 lungcarcinoma; adenocarcinomaSubstitution - Missense

c.157G>A; p.D53N; 12:57435043-57435043

 skinmalignant_melanomaSubstitution - Missense

c.948C>A; p.C316*; 12:57449911-57449911

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Nonsense

c.819G>A; p.M273I; 12:57449782-57449782

 skinmalignant_melanomaSubstitution - Missense

c.746G>A; p.R249Q; 12:57449709-57449709

 large_intestine; rectumcarcinoma; adenocarcinomaSubstitution - Missense

c.486C>T; p.L162L; 12:57449449-57449449

 skinmalignant_melanomaSubstitution - coding silent

c.769C>T; p.R257C; 12:57449732-57449732

 skinmalignant_melanomaSubstitution - Missense

c.965G>A; p.R322Q; 12:57449928-57449928

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense

c.965G>A; p.R322Q; 12:57449928-57449928

 large_intestine; coloncarcinoma; adenocarcinomaSubstitution - Missense

c.965G>A; p.R322Q; 12:57449928-57449928

 haematopoietic_and_lymphoid_tissuehaematopoietic_neoplasm; acute_myeloid_leukaemiaSubstitution - Missense